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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
9.5 DPC

26 matching records from 26 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Fn1  fibronectin 1   (Synonyms: Fn, Fn-1)
Results  Reference
1J:73415 Arthur HM, Ure J, Smith AJ, Renforth G, Wilson DI, Torsney E, Charlton R, Parums DV, Jowett T, Marchuk DA, Burn J, Diamond AG, Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development. Dev Biol. 2000 Jan 1;217(1):42-53
1J:126737 Astrof S, Crowley D, Hynes RO, Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin. Dev Biol. 2007 Nov 1;311(1):11-24
1J:227058 Chen D, Wang X, Liang D, Gordon J, Mittal A, Manley N, Degenhardt K, Astrof S, Fibronectin signals through integrin alpha5beta1 to regulate cardiovascular development in a cell type-specific manner. Dev Biol. 2015 Nov 15;407(2):195-210
1*J:100586 Chuva de Sousa Lopes SM, van den Driesche S, Carvalho RL, Larsson J, Eggen B, Surani MA, Mummery CL, Altered primordial germ cell migration in the absence of transforming growth factor beta signaling via ALK5. Dev Biol. 2005 Aug 1;284(1):194-203
1J:219045 Dai X, Jiang W, Zhang Q, Xu L, Geng P, Zhuang S, Petrich BG, Jiang C, Peng L, Bhattacharya S, Evans SM, Sun Y, Chen J, Liang X, Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis. BMC Biol. 2013;11:107
1J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445
1J:168569 Garita B, Jenkins MW, Han M, Zhou C, Vanauker M, Rollins AM, Watanabe M, Fujimoto JG, Linask KK, Blood flow dynamics of one cardiac cycle and relationship to mechanotransduction and trabeculation during heart looping. Am J Physiol Heart Circ Physiol. 2011 Mar;300(3):H879-91
1J:221408 Garriock RJ, Chalamalasetty RB, Kennedy MW, Canizales LC, Lewandoski M, Yamaguchi TP, Lineage tracing of neuromesodermal progenitors reveals novel Wnt-dependent roles in trunk progenitor cell maintenance and differentiation. Development. 2015 May 1;142(9):1628-38
1J:220469 Grego-Bessa J, Hildebrand J, Anderson KV, Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development. 2015 Apr 1;142(7):1305-14
1J:242026 Heim JB, Squirewell EJ, Neu A, Zocher G, Sominidi-Damodaran S, Wyles SP, Nikolova E, Behrendt N, Saunte DM, Lock-Andersen J, Gaonkar KS, Yan H, Sarkaria JN, Krendel M, van Deursen J, Sprangers R, Stehle T, Bottcher RT, Lee JH, Ordog T, Meves A, Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3933-3938
1J:119566 Ishimura A, Ng JK, Taira M, Young SG, Osada S, Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor beta signaling. Development. 2006 Oct;133(19):3919-28
1J:93842 Marutani T, Yamamoto A, Nagai N, Kubota H, Nagata K, Accumulation of type IV collagen in dilated ER leads to apoptosis in Hsp47-knockout mouse embryos via induction of CHOP. J Cell Sci. 2004 Nov 15;117(Pt 24):5913-22
1*J:165711 Mittal A, Pulina M, Hou SY, Astrof S, Fibronectin and integrin alpha 5 play essential roles in the development of the cardiac neural crest. Mech Dev. 2010 Sep-Dec;127(9-12):472-84
1J:273907 Nandadasa S, Kraft CM, Wang LW, O'Donnell A, Patel R, Gee HY, Grobe K, Cox TC, Hildebrandt F, Apte SS, Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis. Nat Commun. 2019 Feb 27;10(1):953
1J:48254 Ohh M, Yauch RL, Lonergan KM, Whaley JM, Stemmer-Rachamimov AO, Louis DN, Gavin BJ, Kley N, Kaelin WG Jr, Iliopoulos O, The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix. Mol Cell. 1998 Jun;1(7):959-68
1*J:36691 Peters JH, Hynes RO, Fibronectin isoform distribution in the mouse. I. The alternatively spliced EIIIB, EIIIA, and V segments show widespread codistribution in the developing mouse embryo. Cell Adhes Commun. 1996 Aug;4(2):103-25
1J:228847 Ramsbottom SA, Sharma V, Rhee HJ, Eley L, Phillips HM, Rigby HF, Dean C, Chaudhry B, Henderson DJ, Vangl2-regulated polarisation of second heart field-derived cells is required for outflow tract lengthening during cardiac development. PLoS Genet. 2014 Dec;10(12):e1004871
1J:240158 Ray HJ, Niswander LA, Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure. Development. 2016 Apr 01;143(7):1192-204
1*J:18811 Sheppard AM, Onken MD, Rosen GD, Noakes PG, Dean DC, Expanding roles for alpha 4 integrin and its ligands in development. Cell Adhes Commun. 1994 Apr;2(1):27-43
1J:94926 Shiojiri N, Sugiyama Y, Immunolocalization of extracellular matrix components and integrins during mouse liver development. Hepatology. 2004 Aug;40(2):346-55
1J:235626 Sun J, Ting MC, Ishii M, Maxson R, Msx1 and Msx2 function together in the regulation of primordial germ cell migration in the mouse. Dev Biol. 2016 Sep 1;417(1):11-24
1J:177821 Takahashi S, Leiss M, Moser M, Ohashi T, Kitao T, Heckmann D, Pfeifer A, Kessler H, Takagi J, Erickson HP, Fassler R, The RGD motif in fibronectin is essential for development but dispensable for fibril assembly. J Cell Biol. 2007 Jul 2;178(1):167-78
1J:138721 Trindade A, Ram Kumar S, Scehnet JS, Lopes-da-Costa L, Becker J, Jiang W, Liu R, Gill PS, Duarte A, Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos. Blood. 2008 Sep 1;112(5):1720-9
1J:82903 Wendler CC, Schmoldt A, Flentke GR, Case LC, Quadro L, Blaner WS, Lough J, Smith SM, Increased fibronectin deposition in embryonic hearts of retinol-binding protein-null mice. Circ Res. 2003 May 2;92(8):920-8
1J:177837 Xiao Z, Patrakka J, Nukui M, Chi L, Niu D, Betsholtz C, Pikkarainen T, Vainio S, Tryggvason K, Deficiency in crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice. Dev Dyn. 2011 Dec;240(12):2646-56
1*J:16248 Yang JT, Rayburn H, Hynes RO, Embryonic mesodermal defects in alpha 5 integrin-deficient mice. Development. 1993 Dec;119(4):1093-105

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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory