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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
8.5 DPC

14 matching records from 14 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
En2  engrailed 2   (Synonyms: En-2)
Results  Reference
1J:69637 Alavizadeh A, Kiernan AE, Nolan P, Lo C, Steel KP, Bucan M, The wheels mutation in the mouse causes vascular, hindbrain, and inner ear defects. Dev Biol. 2001 Jun 1;234(1):244-60
1J:108723 Andersson O, Reissmann E, Jornvall H, Ibanez CF, Synergistic interaction between Gdf1 and Nodal during anterior axis development. Dev Biol. 2006 May 15;293(2):370-81
1J:108393 Chung AC, Xu X, Niederreither KA, Cooney AJ, Loss of orphan nuclear receptor GCNF function disrupts forebrain development and the establishment of the isthmic organizer. Dev Biol. 2006 May 1;293(1):13-24
1J:142596 Hirano M, Hashimoto S, Yonemura S, Sabe H, Aizawa S, EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition. J Cell Biol. 2008 Sep 22;182(6):1217-30
1J:69594 Hoodless PA, Pye M, Chazaud C, Labbe E, Attisano L, Rossant J, Wrana JL, FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse. Genes Dev. 2001 May 15;15(10):1257-71
1J:59069 Klingensmith J, Ang SL, Bachiller D, Rossant J, Neural induction and patterning in the mouse in the absence of the node and its derivatives. Dev Biol. 1999 Dec 15;216(2):535-49
1*J:60433 Li Song D, Joyner AL, Two Pax2/5/8-binding sites in Engrailed2 are required for proper initiation of endogenous mid-hindbrain expression. Mech Dev. 2000 Feb;90(2):155-65
1J:178623 Madabhushi M, Lacy E, Anterior visceral endoderm directs ventral morphogenesis and placement of head and heart via BMP2 expression. Dev Cell. 2011 Nov 15;21(5):907-19
1J:29682 Matsuo I, Kuratani S, Kimura C, Takeda N, Aizawa S, Mouse Otx2 functions in the formation and patterning of rostral head. Genes Dev. 1995 Nov 1;9(21):2646-58
1J:81152 Mukhopadhyay M, Teufel A, Yamashita T, Agulnick AD, Chen L, Downs KM, Schindler A, Grinberg A, Huang SP, Dorward D, Westphal H, Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation. Development. 2003 Feb;130(3):495-505
1J:98485 Nishioka N, Nagano S, Nakayama R, Kiyonari H, Ijiri T, Taniguchi K, Shawlot W, Hayashizaki Y, Westphal H, Behringer RR, Matsuda Y, Sakoda S, Kondoh H, Sasaki H, Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex. Development. 2005 Jun;132(11):2535-46
1J:95363 Ramos-Mejia V, Escalante-Alcalde D, Kunath T, Ramirez L, Gertsenstein M, Nagy A, Lomeli H, Phenotypic analyses of mouse embryos with ubiquitous expression of Oct4: effects on mid-hindbrain patterning and gene expression. Dev Dyn. 2005 Jan;232(1):180-90
1*J:74631 Tian E, Kimura C, Takeda N, Aizawa S, Matsuo I, Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol. 2002 Feb 15;242(2):204-23
1*J:19212 Wurst W, Auerbach AB, Joyner AL, Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development. 1994 Jul;120(7):2065-75

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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory