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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
7.5 DPC

63 matching records from 63 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cer1  cerberus 1 homolog (Xenopus laevis)   (Synonyms: cer-1, Cerberus-like, Cerl, Cerl1, Cerr1)
Results  Reference
1J:131055 Arnold SJ, Hofmann UK, Bikoff EK, Robertson EJ, Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development. 2008 Feb;135(3):501-11
1J:81247 Beck S, Le Good JA, Guzman M, Ben Haim N, Roy K, Beermann F, Constam DB, Extraembryonic proteases regulate Nodal signalling during gastrulation. Nat Cell Biol. 2002 Dec;4(12):981-5
1*J:44900 Belo JA, Bouwmeester T, Leyns L, Kertesz N, Gallo M, Follettie M, De Robertis EM, Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. Mech Dev. 1997 Nov;68(1-2):45-57
1*J:46377 Biben C, Stanley E, Fabri L, Kotecha S, Rhinn M, Drinkwater C, Lah M, Wang CC, Nash A, Hilton D, Ang SL, Mohun T, Harvey RP, Murine cerberus homologue mCer-1: a candidate anterior patterning molecule. Dev Biol. 1998 Feb 15;194(2):135-51
1*J:61428 Camus A, Davidson BP, Billiards S, Khoo P, Rivera-Perez JA, Wakamiya M, Behringer RR, Tam PP, The morphogenetic role of midline mesendoderm and ectoderm in the development of the forebrain and the midbrain of the mouse embryo. Development. 2000 May;127(9):1799-813
1J:72861 Carver EA, Jiang R, Lan Y, Oram KF, Gridley T, The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol Cell Biol. 2001 Dec;21(23):8184-8
1J:81582 Chen W, Liang Y, Deng W, Shimizu K, Ashique AM, Li E, Li YP, The zinc-finger protein CNBP is required for forebrain formation in the mouse. Development. 2003 Apr;130(7):1367-79
1J:92066 Chu GC, Dunn NR, Anderson DC, Oxburgh L, Robertson EJ, Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo. Development. 2004 Aug;131(15):3501-12
1J:104418 Chu J, Ding J, Jeays-Ward K, Price SM, Placzek M, Shen MM, Non-cell-autonomous role for Cripto in axial midline formation during vertebrate embryogenesis. Development. 2005 Dec;132(24):5539-51
1*J:56972 Constam DB, Robertson EJ, Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping. Development. 2000 Jan;127(2):245-54
1J:186907 D'Andrea D, Liguori GL, Le Good JA, Lonardo E, Andersson O, Constam DB, Persico MG, Minchiotti G, Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction. J Cell Biol. 2008 Feb 11;180(3):597-605
1*J:165751 Du J, Takeuchi H, Leonhard-Melief C, Shroyer KR, Dlugosz M, Haltiwanger RS, Holdener BC, O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation. Dev Biol. 2010 Oct 1;346(1):25-38
1J:68833 Episkopou V, Arkell R, Timmons PM, Walsh JJ, Andrew RL, Swan D, Induction of the mammalian node requires Arkadia function in the extraembryonic lineages. Nature. 2001 Apr 12;410(6830):825-30
1J:154368 Farkas DR, Chapman DL, Kinked tail mutation results in notochord defects in heterozygotes and distal visceral endoderm defects in homozygotes. Dev Dyn. 2009 Oct 29;238(12):3237-3247
1J:165811 Fernandez-Diaz LC, Laurent A, Girasoli S, Turco M, Longobardi E, Iotti G, Jenkins NA, Fiorenza MT, Copeland NG, Blasi F, The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells. Development. 2010 Oct;137(20):3393-403
1J:154679 Fu J, Jiang M, Mirando AJ, Yu HM, Hsu W, Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18598-603
1*J:131814 Fukusumi Y, Naruse C, Asano M, Wtap is required for differentiation of endoderm and mesoderm in the mouse embryo. Dev Dyn. 2008 Mar;237(3):618-29
1*J:122557 Furushima K, Yamamoto A, Nagano T, Shibata M, Miyachi H, Abe T, Ohshima N, Kiyonari H, Aizawa S, Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings. Dev Biol. 2007 Jun 15;306(2):480-92
1J:87048 Gu G, Wells JM, Dombkowski D, Preffer F, Aronow B, Melton DA, Global expression analysis of gene regulatory pathways during endocrine pancreatic development. Development. 2004 Jan;131(1):165-79
1J:77443 Hart AH, Hartley L, Sourris K, Stadler ES, Li R, Stanley EG, Tam PP, Elefanty AG, Robb L, Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo. Development. 2002 Aug;129(15):3597-608
1J:193728 Hong M, Krauss RS, Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice. PLoS Genet. 2012;8(10):e1002999
1J:82316 Hsieh JC, Lee L, Zhang L, Wefer S, Brown K, DeRossi C, Wines ME, Rosenquist T, Holdener BC, Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity. Cell. 2003 Feb 7;112(3):355-67
1J:119566 Ishimura A, Ng JK, Taira M, Young SG, Osada S, Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor beta signaling. Development. 2006 Oct;133(19):3919-28
1*J:75946 Kanai-Azuma M, Kanai Y, Gad JM, Tajima Y, Taya C, Kurohmaru M, Sanai Y, Yonekawa H, Yazaki K, Tam PP, Hayashi Y, Depletion of definitive gut endoderm in Sox17-null mutant mice. Development. 2002 May;129(10):2367-79
1J:91055 Kelly OG, Pinson KI, Skarnes WC, The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice. Development. 2004 Jun;131(12):2803-15
1J:120359 Kimura-Yoshida C, Tian E, Nakano H, Amazaki S, Shimokawa K, Rossant J, Aizawa S, Matsuo I, Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5919-24
1J:74124 Kinder SJ, Tsang TE, Ang SL, Behringer RR, Tam PP, Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity. Int J Dev Biol. 2001;45(1 Spec No):347-55
1*J:71995 Kinder SJ, Tsang TE, Wakamiya M, Sasaki H, Behringer RR, Nagy A, Tam PP, The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm. Development. 2001 Sep;128(18):3623-34
1J:59069 Klingensmith J, Ang SL, Bachiller D, Rossant J, Neural induction and patterning in the mouse in the absence of the node and its derivatives. Dev Biol. 1999 Dec 15;216(2):535-49
1*J:117234 Komatsu Y, Scott G, Nagy A, Kaartinen V, Mishina Y, BMP type I receptor ALK2 is essential for proper patterning at late gastrulation during mouse embryogenesis. Dev Dyn. 2007 Feb;236(2):512-7
1J:164717 Li C, Li YP, Fu XY, Deng CX, Anterior Visceral Endoderm SMAD4 Signaling Specifies Anterior Embryonic Patterning and Head Induction in Mice. Int J Biol Sci. 2010;6(6):569-83
1J:136396 Liao X, Collins MD, All-trans retinoic acid-induced ectopic limb and caudal structures: murine strain sensitivities and pathogenesis. Dev Dyn. 2008 Jun;237(6):1553-64
1J:56511 Liu P, Wakamiya M, Shea MJ, Albrecht U, Behringer RR, Bradley A, Requirement for Wnt3 in vertebrate axis formation. Nat Genet. 1999 Aug;22(4):361-5
1J:178623 Madabhushi M, Lacy E, Anterior visceral endoderm directs ventral morphogenesis and placement of head and heart via BMP2 expression. Dev Cell. 2011 Nov 15;21(5):907-19
1J:164587 Mao J, McKean DM, Warrier S, Corbin JG, Niswander L, Zohn IE, The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure. Development. 2010 Sep;137(18):3079-88
1J:136719 Maretto S, Muller PS, Aricescu AR, Cho KW, Bikoff EK, Robertson EJ, Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3. Dev Biol. 2008 Jun 1;318(1):184-93
1*J:63681 Martinez-Barbera JP, Rodriguez TA, Beddington RS, The homeobox gene Hesx1 is required in the anterior neural ectoderm for normal forebrain formation. Dev Biol. 2000 Jul 15;223(2):422-30
1J:157265 McKnight KD, Hou J, Hoodless PA, Foxh1 and Foxa2 are not required for formation of the midgut and hindgut definitive endoderm. Dev Biol. 2010 Jan 15;337(2):471-81
1*J:86144 Miura S, Mishina Y, Whole-embryo culture of E5.5 mouse embryos: development to the gastrulation stage. Genesis. 2003 Sep;37(1):38-43
1J:159998 Miura S, Singh AP, Mishina Y, Bmpr1a is required for proper migration of the AVE through regulation of Dkk1 expression in the pre-streak mouse embryo. Dev Biol. 2010 May 1;341(1):246-54
1J:163858 Morsut L, Yan KP, Enzo E, Aragona M, Soligo SM, Wendling O, Mark M, Khetchoumian K, Bressan G, Chambon P, Dupont S, Losson R, Piccolo S, Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo. Development. 2010 Aug 1;137(15):2571-8
1J:81152 Mukhopadhyay M, Teufel A, Yamashita T, Agulnick AD, Chen L, Downs KM, Schindler A, Grinberg A, Huang SP, Dorward D, Westphal H, Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation. Development. 2003 Feb;130(3):495-505
1J:98485 Nishioka N, Nagano S, Nakayama R, Kiyonari H, Ijiri T, Taniguchi K, Shawlot W, Hayashizaki Y, Westphal H, Behringer RR, Matsuda Y, Sakoda S, Kondoh H, Sasaki H, Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex. Development. 2005 Jun;132(11):2535-46
1*J:54640 Pearce JJ, Penny G, Rossant J, A mouse cerberus/Dan-related gene family. Dev Biol. 1999 May 1;209(1):98-110
1J:187710 Pereira PN, Dobreva MP, Maas E, Cornelis FM, Moya IM, Umans L, Verfaillie CM, Camus A, de Sousa Lopes SM, Huylebroeck D, Zwijsen A, Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion. Development. 2012 Sep;139(18):3343-54
1J:138699 Piette D, Hendrickx M, Willems E, Kemp CR, Leyns L, An optimized procedure for whole-mount in situ hybridization on mouse embryos and embryoid bodies. Nat Protoc. 2008;3(7):1194-201
1J:205747 Polydorou C, Georgiades P, Ets2-dependent trophoblast signalling is required for gastrulation progression after primitive streak initiation. Nat Commun. 2013;4:1658
1J:119028 Rakeman AS, Anderson KV, Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching. Development. 2006 Aug;133(16):3075-83
1J:75491 Roberts C, Sutherland HF, Farmer H, Kimber W, Halford S, Carey A, Brickman JM, Wynshaw-Boris A, Scambler PJ, Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality. Mol Cell Biol. 2002 Apr;22(7):2318-28
1J:166040 Rocha PP, Scholze M, Bleiss W, Schrewe H, Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling. Development. 2010 Aug;137(16):2723-31
1*J:55840 Saga Y, Miyagawa-Tomita S, Takagi A, Kitajima S, Miyazaki Ji, Inoue T, MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube. Development. 1999 Aug;126(15):3437-47
1*J:47906 Shawlot W, Deng JM, Behringer RR, Expression of the mouse cerberus-related gene, Cerr1, suggests a role in anterior neural induction and somitogenesis. Proc Natl Acad Sci U S A. 1998 May 26;95(11):6198-203
1J:163670 Spruce T, Pernaute B, Di-Gregorio A, Cobb BS, Merkenschlager M, Manzanares M, Rodriguez TA, An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo. Dev Cell. 2010 Aug 17;19(2):207-19
1J:171680 Stuckey DW, Di Gregorio A, Clements M, Rodriguez TA, Correct patterning of the primitive streak requires the anterior visceral endoderm. PLoS One. 2011;6(3):e17620
1*J:51989 Suda Y, Nakabayashi J, Matsuo I, Aizawa S, Functional equivalency between Otx2 and Otx1 in development of the rostral head. Development. 1999 Feb;126(4):743-57
1*J:74631 Tian E, Kimura C, Takeda N, Aizawa S, Matsuo I, Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol. 2002 Feb 15;242(2):204-23
1*J:166847 Tonissoo T, Lulla S, Meier R, Saare M, Ruisu K, Pooga M, Karis A, Nucleotide exchange factor RIC-8 is indispensable in mammalian early development. Dev Dyn. 2010 Dec;239(12):3404-15
1J:84300 Vincent SD, Dunn NR, Hayashi S, Norris DP, Robertson EJ, Cell fate decisions within the mouse organizer are governed by graded Nodal signals. Genes Dev. 2003 Jul 1;17(13):1646-62
1J:106144 Ware SM, Harutyunyan KG, Belmont JW, Zic3 is critical for early embryonic patterning during gastrulation. Dev Dyn. 2006 Mar;235(3):776-85
1J:138862 Warr N, Powles-Glover N, Chappell A, Robson J, Norris D, Arkell RM, Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation. Hum Mol Genet. 2008 Oct 1;17(19):2986-96
1J:86912 Xiao C, Shim JH, Kluppel M, Zhang SS, Dong C, Flavell RA, Fu XY, Wrana JL, Hogan BL, Ghosh S, Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. Genes Dev. 2003 Dec 1;17(23):2933-49
1J:177837 Xiao Z, Patrakka J, Nukui M, Chi L, Niu D, Betsholtz C, Pikkarainen T, Vainio S, Tryggvason K, Deficiency in crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice. Dev Dyn. 2011 Dec;240(12):2646-56
1J:111701 Yeh JR, Ju R, Brdlik CM, Zhang W, Zhang Y, Matyskiela ME, Shotwell JD, Crews CM, Targeted gene disruption of methionine aminopeptidase 2 results in an embryonic gastrulation defect and endothelial cell growth arrest. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10379-84

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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory