Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Vegfa  vascular endothelial growth factor A   (Synonyms: Vegf, VEGF120, VEGF164, VEGF188, VEGF-A, VPF)
Results	Reference
1	J:316273 Bashur LA, Chen D, Chen Z, Liang B, Pardi R, Murakami S, Zhou G, Loss of jab1 in osteochondral progenitor cells severely impairs embryonic limb development in mice. J Cell Physiol. 2014 Nov;229(11):1607-17
1	J:202792 Boucherat O, Montaron S, Berube-Simard FA, Aubin J, Philippidou P, Wellik DM, Dasen JS, Jeannotte L, Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15;304(12):L817-30
1	J:287407 Cai LX, Alkassis FF, Kasahara H, Defective coronary vessel organization and reduction of VEGF-A in mouse embryonic hearts with gestational mild hypoxia. Dev Dyn. 2020 May;249(5):636-645
1	J:267128 Chalothorn D, Faber JE, Formation and maturation of the native cerebral collateral circulation. J Mol Cell Cardiol. 2010 Aug;49(2):251-9
1	J:273652 Chao CM, Moiseenko A, Kosanovic D, Rivetti S, El Agha E, Wilhelm J, Kampschulte M, Yahya F, Ehrhardt H, Zimmer KP, Barreto G, Rizvanov AA, Schermuly RT, Reiss I, Morty RE, Rottier RJ, Bellusci S, Zhang JS, Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia. Hum Mol Genet. 2019 May 1;28(9):1429-1444
1	J:324684 Dang Y, Souchet C, Moresi F, Jeljeli M, Raquillet B, Nicco C, Chouzenoux S, Lagoutte I, Marcellin L, Batteux F, Doridot L, BCG-trained innate immunity leads to fetal growth restriction by altering immune cell profile in the mouse developing placenta. J Leukoc Biol. 2022 May;111(5):1009-1020
1	J:106827 Duvillie B, Currie C, Chrones T, Bucchini D, Jami J, Joshi RL, Hill DJ, Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin. Endocrinology. 2002 Apr;143(4):1530-7
1	J:329983 Fidalgo MF, Fonseca CG, Caldas P, Raposo AA, Balboni T, Henao-Misikova L, Grosso AR, Vasconcelos FF, Franco CA, Aerocyte specification and lung adaptation to breathing is dependent on alternative splicing changes. Life Sci Alliance. 2022 Dec;5(12):e202201554
1	J:151466 Gamer LW, Cox K, Carlo JM, Rosen V, Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures. Dev Dyn. 2009 Aug 3;238(9):2374-2381
1	J:168516 Gordon FE, Nutt CL, Cheunsuchon P, Nakayama Y, Provencher KA, Rice KA, Zhou Y, Zhang X, Klibanski A, Increased expression of angiogenic genes in the brains of mouse meg3-null embryos. Endocrinology. 2010 Jun;151(6):2443-52
1	J:76918 Greenberg JM, Thompson FY, Brooks SK, Shannon JM, McCormick-Shannon K, Cameron JE, Mallory BP, Akeson AL, Mesenchymal expression of vascular endothelial growth factors D and A defines vascular patterning in developing lung. Dev Dyn. 2002 Jun;224(2):144-53
1*	J:248980 Guo H, Kazadaeva Y, Ortega FE, Manjunath N, Desai TJ, Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017 Oct 1;430(1):214-223
1	J:296702 Habuta M, Yasue A, Suzuki KT, Fujita H, Sato K, Kono H, Takayama A, Bando T, Miyaishi S, Oyadomari S, Tanaka E, Ohuchi H, Fgf10-CRISPR mosaic mutants demonstrate the gene dose-related loss of the accessory lobe and decrease in the number of alveolar type 2 epithelial cells in mouse lung. PLoS One. 2020;15(10):e0240333
1	J:316639 He MY, Wang G, Han SS, Jin Y, Li H, Wu X, Ma ZL, Cheng X, Tang X, Yang X, Liu GS, Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta. Open Biol. 2016 Jul;6(7)
1	J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838
1	J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
1	J:188305 Ishijima M, Suzuki N, Hozumi K, Matsunobu T, Kosaki K, Kaneko H, Hassell JR, Arikawa-Hirasawa E, Yamada Y, Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation. Matrix Biol. 2012 May;31(4):234-45
1	J:265611 Jin J, Li Y, Ren J, Man Lam S, Zhang Y, Hou Y, Zhang X, Xu R, Shui G, Ma RZ, Neonatal Respiratory Failure with Retarded Perinatal Lung Maturation in Mice Caused by Reticulocalbin 3 Disruption. Am J Respir Cell Mol Biol. 2016 Mar;54(3):410-23
1	J:269203 Ke H, Masoumi KC, Ahlqvist K, Seckl MJ, Rydell-Tormanen K, Massoumi R, Nemo-like kinase regulates the expression of vascular endothelial growth factor (VEGF) in alveolar epithelial cells. Sci Rep. 2016 Apr 1;6:23987
1	J:130907 Kevill KA, Bhandari V, Kettunen M, Leng L, Fan J, Mizue Y, Dzuira JD, Reyes-Mugica M, McDonald CL, Baugh JA, O'Connor CL, Aghai ZH, Donnelly SC, Bazzy-Asaad A, Bucala RJ, A role for macrophage migration inhibitory factor in the neonatal respiratory distress syndrome. J Immunol. 2008 Jan 1;180(1):601-8
1	J:178426 Kishimoto K, Nishizuka M, Ueda T, Kajita K, Ugawa S, Shimada S, Osada S, Imagawa M, Indispensable role of factor for adipocyte differentiation 104 (fad104) in lung maturation. Exp Cell Res. 2011 Sep 10;317(15):2110-23
1	J:230682 Lucitti JL, Tarte NJ, Faber JE, Chloride intracellular channel 4 is required for maturation of the cerebral collateral circulation. Am J Physiol Heart Circ Physiol. 2015 Oct;309(7):H1141-50
1*	J:231234 Luna RL, Kay VR, Ratsep MT, Khalaj K, Bidarimath M, Peterson N, Carmeliet P, Jin A, Croy BA, Placental growth factor deficiency is associated with impaired cerebral vascular development in mice. Mol Hum Reprod. 2016 Feb;22(2):130-42
1	J:320175 Maeda Y, Miwa Y, Sato I, Expression of CGRP, vasculogenesis and osteogenesis associated mRNAs in the developing mouse mandible and tibia. Eur J Histochem. 2017 Jan 23;61(1):2750
1	J:233282 Maes C, Araldi E, Haigh K, Khatri R, Van Looveren R, Giaccia AJ, Haigh JJ, Carmeliet G, Schipani E, VEGF-independent cell-autonomous functions of HIF-1alpha regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival. J Bone Miner Res. 2012 Mar;27(3):596-609
1*	J:308708 Martinez ME, Hernandez A, The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain. Front Neurosci. 2021;15:703730
1	J:310900 Mesnieres M, Bohm AM, Peredo N, Trompet D, Valle-Tenney R, Bajaj M, Corthout N, Nefyodova E, Cardoen R, Baatsen P, Munck S, Nagy A, Haigh JJ, Khurana S, Verfaillie CM, Maes C, Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches. Cell Rep. 2021 Aug 24;36(8):109618
1*	J:311146 Murata H, Sunohara M, Sato I, Expression of DMP1 in the developing mouse tongue embryo. Ann Anat. 2015 Jul;200:136-48
1	J:239656 Reyahi A, Nik AM, Ghiami M, Gritli-Linde A, Ponten F, Johansson BR, Carlsson P, Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier. Dev Cell. 2015 Jul 06;34(1):19-32
1	J:323229 Rosendahl AH, Monnius M, Laitala A, Railo A, Miinalainen I, Heljasvaara R, Maki JM, Myllyharju J, Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia. J Biol Chem. 2022 Mar 2;298(4):101787
1	J:321171 Safwan-Zaiter H, Wagner N, Michiels JF, Wagner KD, Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging. Cells. 2022 Feb 4;11(3)
1	J:182752 Sasagawa S, Takemori H, Uebi T, Ikegami D, Hiramatsu K, Ikegawa S, Yoshikawa H, Tsumaki N, SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice. Development. 2012 Mar;139(6):1153-63
1	J:316549 Sato I, Miwa Y, Hara S, Fukuyama Y, Sunohara M, Tenomodulin regulated the compartments of embryonic and early postnatal mouse masseter muscle. Ann Anat. 2014 Dec;196(6):410-5
1*	J:180593 Tang W, Yang F, Li Y, de Crombrugghe B, Jiao H, Xiao G, Zhang C, Transcriptional regulation of Vascular Endothelial Growth Factor (VEGF) by osteoblast-specific transcription factor Osterix (Osx) in osteoblasts. J Biol Chem. 2012 Jan 13;287(3):1671-8
1	J:232285 Tibboel J, Groenman FA, Selvaratnam J, Wang J, Tseu I, Huang Z, Caniggia I, Luo D, van Tuyl M, Ackerley C, de Jongste JC, Tibboel D, Post M, Hypoxia-inducible factor-1 stimulates postnatal lung development but does not prevent O2-induced alveolar injury. Am J Respir Cell Mol Biol. 2015 Apr;52(4):448-58
1	J:192736 Tiozzo C, Carraro G, Al Alam D, Baptista S, Danopoulos S, Li A, Lavarreda-Pearce M, Li C, De Langhe S, Chan B, Borok Z, Bellusci S, Minoo P, Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype. J Clin Invest. 2012 Nov 1;122(11):3862-72
1	J:326699 Tosun B, Wolff LI, Houben A, Nutt S, Hartmann C, Osteoclasts and Macrophages-Their Role in Bone Marrow Cavity Formation During Mouse Embryonic Development. J Bone Miner Res. 2022 Jun 11;
1	J:133799 van den Akker NM, Molin DG, Peters PP, Maas S, Wisse LJ, van Brempt R, van Munsteren CJ, Bartelings MM, Poelmann RE, Carmeliet P, Gittenberger-de Groot AC, Tetralogy of fallot and alterations in vascular endothelial growth factor-A signaling and notch signaling in mouse embryos solely expressing the VEGF120 isoform. Circ Res. 2007 Mar 30;100(6):842-9
1	J:112002 van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, Bradley A, Chen Q, Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol. 2006 Aug;169(2):515-27
1	J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70
1	J:318908 Wilson RL, Troja W, Courtney J, Williams A, Jones HN, Placental and fetal characteristics of the Ohia mouse line recapitulate outcomes in human hypoplastic left heart syndrome. Placenta. 2022 Jan;117:131-138
1	J:211804 Woik N, Dietz CT, Schaker K, Kroll J, Kelch-like ECT2-interacting protein KLEIP regulates late-stage pulmonary maturation via Hif-2alpha in mice. Dis Model Mech. 2014 Jun;7(6):683-92
1	J:124125 Yamamoto H, Yun EJ, Gerber HP, Ferrara N, Whitsett JA, Vu TH, Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis. Dev Biol. 2007 Aug 1;308(1):44-53
1	J:126724 Yao Y, Nowak S, Yochelis A, Garfinkel A, Bostrom KI, Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development. J Biol Chem. 2007 Oct 12;282(41):30131-42