Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ucp1  uncoupling protein 1 (mitochondrial, proton carrier)   (Synonyms: Slc25a7)
Results	Reference
1	J:193353 Borensztein M, Viengchareun S, Montarras D, Journot L, Binart N, Lombes M, Dandolo L, Double Myod and Igf2 inactivation promotes brown adipose tissue development by increasing Prdm16 expression. FASEB J. 2012 Nov;26(11):4584-91
1	J:163313 Calo E, Quintero-Estades JA, Danielian PS, Nedelcu S, Berman SD, Lees JA, Rb regulates fate choice and lineage commitment in vivo. Nature. 2010 Aug 26;466(7310):1110-4
1	J:262187 Cautivo KM, Lizama CO, Tapia PJ, Agarwal AK, Garg A, Horton JD, Cortes VA, AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissue. Mol Metab. 2016 Jul;5(7):491-505
1	J:260351 Chen Q, Huang L, Pan D, Zhu LJ, Wang YX, Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis. Cell Rep. 2018 Mar 13;22(11):2860-2872
1	J:260112 Filipova D, Henry M, Rotshteyn T, Brunn A, Carstov M, Deckert M, Hescheler J, Sachinidis A, Pfitzer G, Papadopoulos S, Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5. PLoS One. 2018;13(3):e0194428
1	J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5)
1	J:102703 Fujimoto N, Matsuo N, Sumiyoshi H, Yamaguchi K, Saikawa T, Yoshimatsu H, Yoshioka H, Adiponectin is expressed in the brown adipose tissue and surrounding immature tissues in mouse embryos. Biochim Biophys Acta. 2005 Oct 15;1731(1):1-12
1*	J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82
1*	J:314181 Holzman MA, Ryckman A, Finkelstein TM, Landry-Truchon K, Schindler KA, Bergmann JM, Jeannotte L, Mansfield JH, HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation. Front Cell Dev Biol. 2021;9:632303
1*	J:314174 Jang Y, Park YK, Lee JE, Wan D, Tran N, Gavrilova O, Ge K, MED1 is a lipogenesis coactivator required for postnatal adipose expansion. Genes Dev. 2021 May 1;35(9-10):713-728
1*	J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6
1	J:204551 Park JH, Kang HJ, Kang SI, Lee JE, Hur J, Ge K, Mueller E, Li H, Lee BC, Lee SB, A multifunctional protein, EWS, is essential for early brown fat lineage determination. Dev Cell. 2013 Aug 26;26(4):393-404
1*	J:244382 Park YK, Ge K, Glucocorticoid Receptor Accelerates, but Is Dispensable for, Adipogenesis. Mol Cell Biol. 2017 Jan 15;37(2)
1	J:303562 Park YK, Lee JE, Yan Z, McKernan K, O'Haren T, Wang W, Peng W, Ge K, Interplay of BAF and MLL4 promotes cell type-specific enhancer activation. Nat Commun. 2021 Mar 12;12(1):1630
1	J:244281 Park YK, Wang L, Giampietro A, Lai B, Lee JE, Ge K, Distinct Roles of Transcription Factors KLF4, Krox20, and Peroxisome Proliferator-Activated Receptor gamma in Adipogenesis. Mol Cell Biol. 2017 Jan 15;37(2)
1	J:327433 Song Z, Xiaoli AM, Li Y, Siqin G, Wu T, Strich R, Pessin JE, Yang F, The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation. Mol Metab. 2022 Jul 19;64:101548
1	J:232408 Van De Pette M, Tunster SJ, McNamara GI, Shelkovnikova T, Millership S, Benson L, Peirson S, Christian M, Vidal-Puig A, John RM, Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome. PLoS Genet. 2016 Mar;12(3):e1005916
1	J:269323 Vazquez P, Hernandez-Sanchez C, Escalona-Garrido C, Pereira L, Contreras C, Lopez M, Balsinde J, de Pablo F, Valverde AM, Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation. J Lipid Res. 2018 Dec;59(12):2308-2320
1*	J:236180 Zhou H, Black SM, Benson TW, Weintraub NL, Chen W, Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38