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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
14.5 DPC

20 matching records from 20 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cdkn1c  cyclin-dependent kinase inhibitor 1C (P57)   (Synonyms: CDKI, Kip2, p57Kip2)
Results  Reference
1J:59880 Blixt A, Mahlapuu M, Aitola M, Pelto-Huikko M, Enerback S, Carlsson P, A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle. Genes Dev. 2000 Jan 15;14(2):245-54
1J:177885 Brunskill EW, Georgas K, Rumballe B, Little MH, Potter SS, Defining the molecular character of the developing and adult kidney podocyte. PLoS One. 2011;6(9):e24640
1J:229227 Colasante G, Simonet JC, Calogero R, Crispi S, Sessa A, Cho G, Golden JA, Broccoli V, ARX regulates cortical intermediate progenitor cell expansion and upper layer neuron formation through repression of Cdkn1c. Cereb Cortex. 2015 Feb;25(2):322-35
1J:171198 Cwinn MA, Mazerolle C, McNeill B, Ringuette R, Thurig S, Hui CC, Wallace VA, Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina. J Neurosci. 2011 Mar 30;31(13):5169-80
1J:271140 Diacou R, Zhao Y, Zheng D, Cvekl A, Liu W, Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation. Cell Rep. 2018 Nov 27;25(9):2510-2523.e4
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:63217 Dyer MA, Cepko CL, p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina. Development. 2000 Aug;127(16):3593-605
1J:196080 Elsen GE, Hodge RD, Bedogni F, Daza RA, Nelson BR, Shiba N, Reiner SL, Hevner RF, The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
1*J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1J:208421 Klimova L, Kozmik Z, Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development. 2014 Mar;141(6):1292-302
1*J:57066 Lovicu FJ, McAvoy JW, Spatial and temporal expression of p57(KIP2) during murine lens development. Mech Dev. 1999 Aug;86(1-2):165-9
1*J:85738 MacLean HE, Kim JI, Glimcher MJ, Wang J, Kronenberg HM, Glimcher LH, Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol. 2003 Oct 1;262(1):51-63
1J:179730 Mairet-Coello G, Tury A, Van Buskirk E, Robinson K, Genestine M, Dicicco-Bloom E, p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex. Development. 2012 Feb;139(3):475-87
1*J:24409 Matsuoka S, Edwards MC, Bai C, Parker S, Zhang P, Baldini A, Harper JW, Elledge SJ, p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev. 1995 Mar 15;9(6):650-62
1J:101355 Medina-Martinez O, Brownell I, Amaya-Manzanares F, Hu Q, Behringer RR, Jamrich M, Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice. Mol Cell Biol. 2005 Oct;25(20):8854-63
1J:109091 Nguyen L, Besson A, Heng JI, Schuurmans C, Teboul L, Parras C, Philpott A, Roberts JM, Guillemot F, p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex. Genes Dev. 2006 Jun 1;20(11):1511-24
1J:161410 Oh-McGinnis R, Bogutz AB, Lee KY, Higgins MJ, Lefebvre L, Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome. BMC Dev Biol. 2010;10:50
1*J:93571 Rowan S, Chen CM, Young TL, Fisher DE, Cepko CL, Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development. 2004 Oct;131(20):5139-52
1J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6

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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory