Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Vegfa  vascular endothelial growth factor A   (Synonyms: Vegf, VEGF120, VEGF164, VEGF188, VEGF-A, VPF)
Results	Reference
1	J:186528 Bainbridge SA, Minhas A, Whiteley KJ, Qu D, Sled JG, Kingdom JC, Adamson SL, Effects of reduced Gcm1 expression on trophoblast morphology, fetoplacental vascularity, and pregnancy outcomes in mice. Hypertension. 2012 Mar;59(3):732-9
1	J:304446 Beckert V, Rassmann S, Kayvanjoo AH, Klausen C, Bonaguro L, Botermann DS, Krause M, Moreth K, Spielmann N, da Silva-Buttkus P, Fuchs H, Gailus-Durner V, de Angelis MH, Handler K, Ulas T, Aschenbrenner AC, Mass E, Wachten D, Creld1 regulates myocardial development and function. J Mol Cell Cardiol. 2021 Mar 24;156:45-56
1	J:159112 Bohmer R, Neuhaus B, Buhren S, Zhang D, Stehling M, Bock B, Kiefer F, Regulation of developmental lymphangiogenesis by Syk(+) leukocytes. Dev Cell. 2010 Mar 16;18(3):437-49
1	J:234630 Bonney S, Harrison-Uy S, Mishra S, MacPherson AM, Choe Y, Li D, Jaminet SC, Fruttiger M, Pleasure SJ, Siegenthaler JA, Diverse Functions of Retinoic Acid in Brain Vascular Development. J Neurosci. 2016 Jul 20;36(29):7786-801
1	J:239317 Bourke LM, Del Monte-Nieto G, Outhwaite JE, Bharti V, Pollock PM, Simmons DG, Adam A, Hur SS, Maghzal GJ, Whitelaw E, Stocker R, Suter CM, Harvey RP, Harten SK, Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse. Differentiation. 2017 Mar - Apr;94:8-20
1	J:203143 Bryson JL, Griffith AV, Hughes B 3rd, Saito F, Takahama Y, Richie ER, Manley NR, Cell-autonomous defects in thymic epithelial cells disrupt endothelial-perivascular cell interactions in the mouse thymus. PLoS One. 2013;8(6):e65196
1	J:169003 Cool J, DeFalco TJ, Capel B, Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):167-72
1	J:171226 Cullen M, Elzarrad MK, Seaman S, Zudaire E, Stevens J, Yang MY, Li X, Chaudhary A, Xu L, Hilton MB, Logsdon D, Hsiao E, Stein EV, Cuttitta F, Haines DC, Nagashima K, Tessarollo L, St Croix B, GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5759-64
1	J:147285 Eshkar-Oren I, Viukov SV, Salameh S, Krief S, Oh CD, Akiyama H, Gerber HP, Ferrara N, Zelzer E, The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf. Development. 2009 Apr;136(8):1263-72
1	J:331421 Funato N, Yanagisawa H, TBX1 targets the miR-200-ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties. Sci Rep. 2022 Nov 23;12(1):20188
1	J:76918 Greenberg JM, Thompson FY, Brooks SK, Shannon JM, McCormick-Shannon K, Cameron JE, Mallory BP, Akeson AL, Mesenchymal expression of vascular endothelial growth factors D and A defines vascular patterning in developing lung. Dev Dyn. 2002 Jun;224(2):144-53
1	J:316639 He MY, Wang G, Han SS, Jin Y, Li H, Wu X, Ma ZL, Cheng X, Tang X, Yang X, Liu GS, Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta. Open Biol. 2016 Jul;6(7)
1*	J:65677 Healy AM, Morgenthau L, Zhu X, Farber HW, Cardoso WV, VEGF is deposited in the subepithelial matrix at the leading edge of branching airways and stimulates neovascularization in the murine embryonic lung. Dev Dyn. 2000 Nov;219(3):341-52
1	J:215459 Hellbach N, Weise SC, Vezzali R, Wahane SD, Heidrich S, Roidl D, Pruszak J, Esser JS, Vogel T, Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome. Hum Mol Genet. 2014 Dec 1;23(23):6177-90
1	J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22
1	J:245044 Janssen L, Dupont L, Bekhouche M, Noel A, Leduc C, Voz M, Peers B, Cataldo D, Apte SS, Dubail J, Colige A, ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis. Angiogenesis. 2016 Jan;19(1):53-65
1	J:282322 Ko HR, Hwang I, Jin EJ, Yun T, Ryu D, Kang JS, Park KW, Shin JH, Cho SW, Lee KH, Ye K, Ahn JY, Roles of ErbB3-binding protein 1 (EBP1) in embryonic development and gene-silencing control. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24852-24860
1	J:231532 Lange C, Turrero Garcia M, Decimo I, Bifari F, Eelen G, Quaegebeur A, Boon R, Zhao H, Boeckx B, Chang J, Wu C, Le Noble F, Lambrechts D, Dewerchin M, Kuo CJ, Huttner WB, Carmeliet P, Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis. EMBO J. 2016 May 2;35(9):924-41
1	J:109722 Lavine KJ, White AC, Park C, Smith CS, Choi K, Long F, Hui CC, Ornitz DM, Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development. Genes Dev. 2006 Jun 15;20(12):1651-66
1*	J:237064 Lenti E, Farinello D, Yokoyama KK, Penkov D, Castagnaro L, Lavorgna G, Wuputra K, Sandell LL, Tjaden NE, Bernassola F, Caridi N, De Antoni A, Wagner M, Kozinc K, Niederreither K, Blasi F, Pasini D, Majdic G, Tonon G, Trainor PA, Brendolan A, Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development. J Clin Invest. 2016 Jul 01;126(7):2452-64
1	J:250062 Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P, Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol. 2016 Mar 16;14:19
1	J:259048 Liu X, Wang Y, Liu F, Zhang M, Song H, Zhou B, Lo CW, Tong S, Hu Z, Zhang Z, Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling. Sci Signal. 2018 Feb 27;11(519)
1	J:199431 Macdonald ST, Bamforth SD, Braganca J, Chen CM, Broadbent C, Schneider JE, Schwartz RJ, Bhattacharya S, A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular development. Eur Heart J. 2013 Aug;34(32):2557-2565
1	J:214759 McKenna CC, Ojeda AF, Spurlin J 3rd, Kwiatkowski S, Lwigale PY, Sema3A maintains corneal avascularity during development by inhibiting Vegf induced angioblast migration. Dev Biol. 2014 Jul 15;391(2):241-50
1*	J:196288 Nechiporuk T, Klezovitch O, Nguyen L, Vasioukhin V, Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis. Dev Biol. 2013 May 15;377(2):375-84
1	J:146692 Saint-Geniez M, Kurihara T, D'Amore PA, Role of cell and matrix-bound VEGF isoforms in lens development. Invest Ophthalmol Vis Sci. 2009 Jan;50(1):311-21
1	J:323013 Sakai D, Sugawara T, Kurokawa T, Murakami Y, Tomosugi M, Masuta H, Sakata-Haga H, Hatta T, Shoji H, Hif1alpha-dependent hypoxia signaling contributes to the survival of deep-layer neurons and cortex formation in a mouse model. Mol Brain. 2022 Mar 31;15(1):28
1	J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49
1	J:237433 Tillo M, Erskine L, Cariboni A, Fantin A, Joyce A, Denti L, Ruhrberg C, VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain. Development. 2015 Jan 15;142(2):314-9
1	J:125010 Tracy K, Dibling BC, Spike BT, Knabb JR, Schumacker P, Macleod KF, BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. Mol Cell Biol. 2007 Sep;27(17):6229-42
1	J:119174 van Tuyl M, Groenman F, Wang J, Kuliszewski M, Liu J, Tibboel D, Post M, Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs. Dev Biol. 2007 Mar 15;303(2):514-526
1	J:311813 VanDusen NJ, Casanovas J, Vincentz JW, Firulli BA, Osterwalder M, Lopez-Rios J, Zeller R, Zhou B, Grego-Bessa J, De La Pompa JL, Shou W, Firulli AB, Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium. Cell Rep. 2014 Dec 24;9(6):2071-83
1	J:341382 Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y, Zhou B, Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683
1*	J:99650 Zhao L, Wang K, Ferrara N, Vu TH, Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature. Mech Dev. 2005 Jul-Aug;122(7-8):877-86