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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
13.5 DPC

23 matching records from 23 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Fgfr2  fibroblast growth factor receptor 2   (Synonyms: Bek, Fgfr-2, Fgfr7, Fgfr-7, KGFRTr, svs)
Results  Reference
1J:91667 Antonopoulou I, Mavrogiannis LA, Wilkie AO, Morriss-Kay GM, Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. J Anat. 2004 Jun;204(6):487-99
1J:85881 Bansal R, Lakhina V, Remedios R, Tole S, Expression of FGF receptors 1, 2, 3 in the embryonic and postnatal mouse brain compared with Pdgfralpha, Olig2 and Plp/dm20: implications for oligodendrocyte development. Dev Neurosci. 2003 Mar-Aug;25(2-4):83-95
1J:108824 Casey LM, Lan Y, Cho ES, Maltby KM, Gridley T, Jiang R, Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development. Dev Dyn. 2006 Apr 10;235(7):1830-1844
1J:137155 Hayashi T, Ray CA, Bermingham-McDonogh O, Fgf20 is required for sensory epithelial specification in the developing cochlea. J Neurosci. 2008 Jun 4;28(23):5991-9
1*J:156926 Hayashi T, Ray CA, Younkins C, Bermingham-McDonogh O, Expression patterns of FGF receptors in the developing mammalian cochlea. Dev Dyn. 2010 Feb 3;239(3):1019-1026
1J:103321 Hilliard SA, Yu L, Gu S, Zhang Z, Chen YP, Regional regulation of palatal growth and patterning along the anterior-posterior axis in mice. J Anat. 2005 Nov;207(5):655-67
1J:149465 Holmes G, Rothschild G, Roy UB, Deng CX, Mansukhani A, Basilico C, Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology. Dev Biol. 2009 Apr 15;328(2):273-84
1J:155751 Kang W, Wong LC, Shi SH, Hebert JM, The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis. J Neurosci. 2009 Nov 18;29(46):14571-80
1J:48564 Kettunen P, Karavanova I, Thesleff I, Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9. Dev Genet. 1998;22(4):374-85
1J:190644 Khonsari RH, Delezoide AL, Kang W, Hebert JM, Bessieres B, Bodiguel V, Collet C, Legeai-Mallet L, Sharpe PT, Fallet-Bianco C, Central nervous system malformations and deformations in FGFR2-related craniosynostosis. Am J Med Genet A. 2012 Nov;158A(11):2797-806
1J:119280 Klein OD, Minowada G, Peterkova R, Kangas A, Yu BD, Lesot H, Peterka M, Jernvall J, Martin GR, Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signaling. Dev Cell. 2006 Aug;11(2):181-90
1J:144626 Liu W, Lan Y, Pauws E, Meester-Smoor MA, Stanier P, Zwarthoff EC, Jiang R, The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice. Development. 2008 Dec;135(23):3959-68
1J:170635 Nichol PF, Corliss RF, Tyrrell JD, Graham B, Reeder A, Saijoh Y, Conditional mutation of fibroblast growth factor receptors 1 and 2 results in an omphalocele in mice associated with disruptions in ventral body wall muscle formation. J Pediatr Surg. 2011 Jan;46(1):90-6
1J:186261 Reeder AL, Botham RA, Franco M, Zaremba KM, Nichol PF, Formation of intestinal atresias in the Fgfr2IIIb-/- mice is not associated with defects in notochord development or alterations in Shh expression. J Surg Res. 2012 Apr 29;
1J:67731 Revest JM, Spencer-Dene B, Kerr K, De Moerlooze L, Rosewell I, Dickson C, Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4. Dev Biol. 2001 Mar 1;231(1):47-62
1J:70820 Revest JM, Suniara RK, Kerr K, Owen JJ, Dickson C, Development of the thymus requires signaling through the fibroblast growth factor receptor r2-iiib. J Immunol. 2001 Aug 15;167(4):1954-61
1*J:98808 Rice R, Rice DP, Thesleff I, Foxc1 integrates Fgf and Bmp signalling independently of twist or noggin during calvarial bone development. Dev Dyn. 2005 May 19;233(3):847-852
1J:90909 Rice R, Spencer-Dene B, Connor EC, Gritli-Linde A, McMahon AP, Dickson C, Thesleff I, Rice DP, Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest. 2004 Jun;113(12):1692-700
1J:105169 Sasaki T, Ito Y, Bringas P Jr, Chou S, Urata MM, Slavkin H, Chai Y, TGF{beta}-mediated FGF signaling is crucial for regulating cranial neural crest cell proliferation during frontal bone development. Development. 2006 Jan;133(2):371-81
1*J:157563 Snyder-Warwick AK, Perlyn CA, Pan J, Yu K, Zhang L, Ornitz DM, Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2515-20
1J:204465 Volckaert T, Campbell A, Dill E, Li C, Minoo P, De Langhe S, Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors. Development. 2013 Sep;140(18):3731-42
1J:125229 Welsh IC, Hagge-Greenberg A, O'brien TP, A dosage-dependent role for Spry2 in growth and patterning during palate development. Mech Dev. 2007 Sep-Oct;124(9-10):746-61
1J:101732 Yu L, Gu S, Alappat S, Song Y, Yan M, Zhang X, Zhang G, Jiang Y, Zhang Z, Zhang Y, Chen Y, Shox2-deficient mice exhibit a rare type of incomplete clefting of the secondary palate. Development. 2005 Oct;132(19):4397-406

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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory