Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Igf2  insulin-like growth factor 2   (Synonyms: Igf-2, Igf-II, M6pr, Mpr, Peg2)
Results	Reference
1*	J:120667 Bouzin C, Clotman F, Renauld JC, Lemaigre FP, Rousseau GG, The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver. J Immunol. 2003 Aug 1;171(3):1297-303
1*	J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9
1	J:305124 Czepukojc B, Abuhaliema A, Barghash A, Tierling S, Nass N, Simon Y, Korbel C, Cadenas C, van Hul N, Sachinidis A, Hengstler JG, Helms V, Laschke MW, Walter J, Haybaeck J, Leclercq I, Kiemer AK, Kessler SM, IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis. Front Med (Lausanne). 2019;6:179
1*	J:767 Hannon K, Smith CK 2nd, Bales KR, Santerre RF, Temporal and quantitative analysis of myogenic regulatory and growth factor gene expression in the developing mouse embryo. Dev Biol. 1992 May;151(1):137-44
1	J:167738 Hardouin SN, Guo R, Romeo PH, Nagy A, Aubin JE, Impaired mesenchymal stem cell differentiation and osteoclastogenesis in mice deficient for Igf2-P2 transcripts. Development. 2011 Jan;138(2):203-13
1	J:49355 Hatano N, Eversole-Cire P, Ferguson-Smith AC, Jones PA, Surani MA, Sasaki H, Enhancer-dependent, locus-wide regulation of the imprinted mouse insulin-like growth factor II gene. J Biochem. 1998 May;123(5):984-91
1*	J:192195 Himes KP, Koppes E, Chaillet JR, Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth. Dev Biol. 2013 Jan 1;373(1):72-82
1	J:123251 Holm PC, Mader MT, Haubst N, Wizenmann A, Sigvardsson M, Gotz M, Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon. Mol Cell Neurosci. 2007 Jan;34(1):99-119
1	J:159511 Kawahara M, Wu Q, Kono T, Involvement of insulin-like growth factor 2 in angiogenic factor transcription in Bi-maternal mouse conceptuses. J Reprod Dev. 2010 Feb;56(1):79-85
1*	J:75350 Kono T, Sotomaru Y, Katsuzawa Y, Dandolo L, Mouse parthenogenetic embryos with monoallelic h19 expression can develop to day 17.5 of gestation. Dev Biol. 2002 Mar 15;243(2):294-300
1	J:171220 Li P, Cavallero S, Gu Y, Chen TH, Hughes J, Hassan AB, Bruning JC, Pashmforoush M, Sucov HM, IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development. Development. 2011 May;138(9):1795-805
1	J:317705 Matsuzaki H, Miyajima Y, Fukamizu A, Tanimoto K, Orientation of mouse H19 ICR affects imprinted H19 gene expression through promoter methylation-dependent and -independent mechanisms. Commun Biol. 2021 Dec 17;4(1):1410
1*	J:226694 Matsuzaki H, Okamura E, Takahashi T, Ushiki A, Nakamura T, Nakano T, Hata K, Fukamizu A, Tanimoto K, De novo DNA methylation through the 5'-segment of the H19 ICR maintains its imprint during early embryogenesis. Development. 2015 Nov 15;142(22):3833-44
1	J:181833 Messerschmidt DM, de Vries W, Ito M, Solter D, Ferguson-Smith A, Knowles BB, Trim28 is required for epigenetic stability during mouse oocyte to embryo transition. Science. 2012 Mar 23;335(6075):1499-502
1*	J:126194 Nagata K, Masumoto K, Uesugi T, Yamamoto S, Yoshizaki K, Fukumoto S, Nonaka K, Taguchi T, Effect of insulin-like-growth factor and its receptors regarding lung development in fetal mice. Pediatr Surg Int. 2007 Oct;23(10):953-9
1*	J:47783 Obata Y, Kaneko-Ishino T, Koide T, Takai Y, Ueda T, Domeki I , Shiroishi T , Ishino F , Kono T, Disruption of primary imprinting during oocyte growth leads to the modified expression of imprinted genes during embryogenesis. Development. 1998 Apr;125(8):1553-60
1	J:268910 Segura-Bayona S, Knobel PA, Gonzalez-Buron H, Youssef SA, Pena-Blanco A, Coyaud E, Lopez-Rovira T, Rein K, Palenzuela L, Colombelli J, Forrow S, Raught B, Groth A, de Bruin A, Stracker TH, Differential requirements for Tousled-like kinases 1 and 2 in mammalian development. Cell Death Differ. 2017 Nov;24(11):1872-1885
1*	J:152946 Sferruzzi-Perri AN, Macpherson AM, Roberts CT, Robertson SA, Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice. Biol Reprod. 2009 Jul;81(1):207-21
1	J:275000 Sharma A, Lacko LA, Argueta LB, Glendinning MD, Stuhlmann H, miR-126 regulates glycogen trophoblast proliferation and DNA methylation in the murine placenta. Dev Biol. 2019 May 1;449(1):21-34
1	J:305574 Shen H, Gan P, Wang K, Darehzereshki A, Wang K, Kumar SR, Lien CL, Patterson M, Tao G, Sucov HM, Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling. Elife. 2020 Mar 13;9:e53071
1	J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306
1	J:256746 Wang X, Shan X, Gregory-Evans CY, A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye. Biochim Biophys Acta. 2017 Jan;1863(1):60-67
1	J:184585 Yamamoto M, Matsuzaki T, Takahashi R, Adachi E, Maeda Y, Yamaguchi S, Kitayama H, Echizenya M, Morioka Y, Alexander DB, Yagi T, Itohara S, Nakamura T, Akiyama H, Noda M, The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs. Biol Open. 2012;1(5):458-466
1	J:265506 Younis S, Schonke M, Massart J, Hjortebjerg R, Sundstrom E, Gustafson U, Bjornholm M, Krook A, Frystyk J, Zierath JR, Andersson L, The ZBED6-IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E2048-E2057
1*	J:101358 Zekri L, Chebli K, Tourriere H, Nielsen FC, Hansen TV, Rami A, Tazi J, Control of fetal growth and neonatal survival by the RasGAP-associated endoribonuclease G3BP. Mol Cell Biol. 2005 Oct;25(19):8703-16