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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
11.5 DPC

14 matching records from 14 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Dkk1  dickkopf WNT signaling pathway inhibitor 1   (Synonyms: mdkk-1)
Results  Reference
1J:165759 Chiu HS, Szucsik JC, Georgas KM, Jones JL, Rumballe BA, Tang D, Grimmond SM, Lewis AG, Aronow BJ, Lessard JL, Little MH, Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation. Dev Biol. 2010 Aug 15;344(2):1071-87
1J:177793 Combes AN, Bowles J, Feng CW, Chiu HS, Khoo PL, Jackson A, Little MH, Tam PP, Koopman P, Expression and functional analysis of Dkk1 during early gonadal development. Sex Dev. 2011;5(3):124-30
1J:137914 Ellwanger K, Saito H, Clement-Lacroix P, Maltry N, Niedermeyer J, Lee WK, Baron R, Rawadi G, Westphal H, Niehrs C, Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density. Mol Cell Biol. 2008 Aug;28(15):4875-82
1J:200023 Farin HF, Ludtke TH, Schmidt MK, Placzko S, Schuster-Gossler K, Petry M, Christoffels VM, Kispert A, Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1. PLoS Genet. 2013;9(4):e1003467
1J:79899 Grotewold L, Ruther U, The Fused toes (Ft) mouse mutation causes anteroposterior and dorsoventral polydactyly. Dev Biol. 2002 Nov 1;251(1):129-41
1J:115359 Grotewold L, Ruther U, The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death. EMBO J. 2002 Mar 1;21(5):966-75
1*J:58627 Grotewold L, Theil T, Ruther U, Expression pattern of Dkk-1 during mouse limb development. Mech Dev. 1999 Dec;89(1-2):151-3
1J:241980 Guo C, Sun Y, Guo C, MacDonald BT, Borer JG, Li X, Dkk1 in the peri-cloaca mesenchyme regulates formation of anorectal and genitourinary tracts. Dev Biol. 2014 Jan 01;385(1):41-51
1*J:160259 Lieven O, Knobloch J, Ruther U, The regulation of Dkk1 expression during embryonic development. Dev Biol. 2010 Apr 15;340(2):256-68
1J:91047 MacDonald BT, Adamska M, Meisler MH, Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6. Development. 2004 Jun;131(11):2543-52
1J:143586 Manuylov NL, Smagulova FO, Leach L, Tevosian SG, Ovarian development in mice requires the GATA4-FOG2 transcription complex. Development. 2008 Nov;135(22):3731-43
1*J:57798 Monaghan AP, Kioschis P, Wu W, Zuniga A, Bock D, Poustka A, Delius H, Niehrs C, Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev. 1999 Sep;87(1-2):45-56
1J:216214 Raspopovic J, Marcon L, Russo L, Sharpe J, Modeling digits. Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients. Science. 2014 Aug 1;345(6196):566-70
1*J:146657 Witte F , Dokas J , Neuendorf F , Mundlos S , Stricker S, Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. Gene Expr Patterns. 2009 Apr;9(4):215-23

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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory