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Gene Expression Literature Summary
Assay
Age
RT-PCR
10.5 DPC

7 matching records from 7 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nkx2-1  NK2 homeobox 1   (Synonyms: T/EBP, thyroid-specific enhancer-binding protein, thyroid transcription factor-1, tinman, Titf1, Ttf-1)
Results  Reference
1J:169134 Domyan ET, Ferretti E, Throckmorton K, Mishina Y, Nicolis SK, Sun X, Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2. Development. 2011 Mar;138(5):971-81
1J:297740 Eto H, Kishi Y, Yakushiji-Kaminatsui N, Sugishita H, Utsunomiya S, Koseki H, Gotoh Y, The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon. Nat Commun. 2020 Nov 11;11(1):5709
1J:213659 Fausett SR, Brunet LJ, Klingensmith J, BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis. Dev Biol. 2014 Jul 1;391(1):111-24
1J:194843 Ferri A, Favaro R, Beccari L, Bertolini J, Mercurio S, Nieto-Lopez F, Verzeroli C, La Regina F, De Pietri Tonelli D, Ottolenghi S, Bovolenta P, Nicolis SK, Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh. Development. 2013 Mar;140(6):1250-61
1*J:310130 Jia S, Zhang L, Zhang K, Wang L, Khan A, Zhang J, Sun Y, Wang Y, Song M, Lyu Y, Li M, Lu X, Niu B, Liu Z, Xie J, Nkx2.1 downregulation is involved in brain abnormality induced by excess retinoic acid. Acta Biochim Biophys Sin (Shanghai). 2020 Jun 20;52(6):683-690
1J:312414 Yogosawa S, Ohkido M, Horii T, Okazaki Y, Nakayama J, Yoshida S, Toyokuni S, Hatada I, Morimoto M, Yoshida K, Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient. Commun Biol. 2021 Oct 20;4(1):1204
1J:171767 Zhang W, Hong M, Bae GU, Kang JS, Krauss RS, Boc modifies the holoprosencephaly spectrum of Cdo mutant mice. Dis Model Mech. 2011 May-Jun;4(3):368-80

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory