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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
10.5 DPC

18 matching records from 18 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Dkk1  dickkopf WNT signaling pathway inhibitor 1   (Synonyms: mdkk-1)
Results  Reference
1*J:92327 Adamska M, MacDonald BT, Sarmast ZH, Oliver ER, Meisler MH, En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Dev Biol. 2004 Aug 1;272(1):134-44
1J:173627 Billington CJ Jr, Ng B, Forsman C, Schmidt B, Bagchi A, Symer DE, Schotta G, Gopalakrishnan R, Sarver AL, Petryk A, The molecular and cellular basis of variable craniofacial phenotypes and their genetic rescue in Twisted gastrulation mutant mice. Dev Biol. 2011 Jul 1;355(1):21-31
1J:152865 Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH, Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol. 2009 Aug 15;332(2):273-86
1J:171615 Georgas KM, Chiu HS, Lesieur E, Rumballe BA, Little MH, Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Dev Dyn. 2011 Jun;240(6):1600-12
1J:115359 Grotewold L, Ruther U, The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death. EMBO J. 2002 Mar 1;21(5):966-75
1*J:58627 Grotewold L, Theil T, Ruther U, Expression pattern of Dkk-1 during mouse limb development. Mech Dev. 1999 Dec;89(1-2):151-3
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1J:241980 Guo C, Sun Y, Guo C, MacDonald BT, Borer JG, Li X, Dkk1 in the peri-cloaca mesenchyme regulates formation of anorectal and genitourinary tracts. Dev Biol. 2014 Jan 01;385(1):41-51
1*J:171052 Itou J, Taniguchi N, Oishi I, Kawakami H, Lotz M, Kawakami Y, HMGB factors are required for posterior digit development through integrating signaling pathway activities. Dev Dyn. 2011 May;240(5):1151-62
1J:208421 Klimova L, Kozmik Z, Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development. 2014 Mar;141(6):1292-302
1J:102949 Li C, Xu X, Nelson DK, Williams T, Kuehn MR, Deng CX, FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis. Development. 2005 Nov;132(21):4755-64
1J:225380 Lieven O, Dronka J, Burmuhl S, Ruther U, Differential binding of Lef1 and Msx1/2 transcription factors to Dkk1 CNEs correlates with reporter gene expression in vivo. PLoS One. 2014;9(12):e115442
1*J:160259 Lieven O, Knobloch J, Ruther U, The regulation of Dkk1 expression during embryonic development. Dev Biol. 2010 Apr 15;340(2):256-68
1J:173635 Lieven O, Ruther U, The Dkk1 dose is critical for eye development. Dev Biol. 2011 Jul 1;355(1):124-37
1*J:57798 Monaghan AP, Kioschis P, Wu W, Zuniga A, Bock D, Poustka A, Delius H, Niehrs C, Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev. 1999 Sep;87(1-2):45-56
1J:71787 Mukhopadhyay M, Shtrom S, Rodriguez-Esteban C, Chen L, Tsukui T, Gomer L, Dorward DW, Glinka A, Grinberg A, Huang SP, Niehrs C, Belmonte JC, Westphal H, Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Dev Cell. 2001 Sep;1(3):423-34
1J:101736 Verheyden JM, Lewandoski M, Deng C, Harfe BD, Sun X, Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning. Development. 2005 Oct;132(19):4235-45
1*J:146657 Witte F , Dokas J , Neuendorf F , Mundlos S , Stricker S, Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. Gene Expr Patterns. 2009 Apr;9(4):215-23

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last database update
04/09/2019
MGI 6.13
The Jackson Laboratory