Gene Expression Literature Summary

• Symbol: Lamb3
• Name: laminin, beta 3
• ID: MGI:99915

40 matching records from 40 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8	E8.5	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19.5	E20	E	P
Immunohistochemistry (section)	1			2		1	2	1		3	1	3	2	4	1	3		5	1	1	1	4	1	1	1	10
In situ RNA (section)				2		1		3		3		3		4		4		4	1	1		4	1	1	1	4
In situ RNA (whole mount)				1
In situ reporter (knock in)																										1
Northern blot													1					1								2
Western blot		1	1									1		1		2		1				1				1
RT-PCR					1				1	2	1	2	3	3	2	2	2	2	1		1	2				10
cDNA clones																										3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lamb3  laminin, beta 3   (Synonyms: nicein, 125kDa)
Results	Reference
18*	J:38997 Aberdam D, Aguzzi A, Baudoin C, Galliano MF, Ortonne JP, Meneguzzi G, Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles. Cell Adhes Commun. 1994 Jun;2(2):115-29
4	J:17618 Aberdam D, Galliano MF, Mattei MG, Pisani-Spadafora A, Ortonne JP, Meneguzzi G, Assignment of mouse nicein genes to chromosomes 1 and 18. Mamm Genome. 1994 Apr;5(4):229-33
2	J:257034 Beisaw A, Tsaytler P, Koch F, Schmitz SU, Melissari MT, Senft AD, Wittler L, Pennimpede T, Macura K, Herrmann BG, Grote P, BRACHYURY directs histone acetylation to target loci during mesoderm development. EMBO Rep. 2018 Jan;19(1):118-134
3	J:173927 Copp AJ, Carvalho R, Wallace A, Sorokin L, Sasaki T, Greene ND, Ybot-Gonzalez P, Regional differences in the expression of laminin isoforms during mouse neural tube development. Matrix Biol. 2011 May;30(4):301-9
1	J:108241 Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Culiat CT, Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Hum Mol Genet. 2006 Apr 15;15(8):1329-41
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:77644 Dowling J, Yu QC, Fuchs E, Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival. J Cell Biol. 1996 Jul;134(2):559-72
1	J:237202 Fantauzzo KA, Soriano P, PDGFRbeta regulates craniofacial development through homodimers and functional heterodimers with PDGFRalpha. Genes Dev. 2016 Nov 01;30(21):2443-2458
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1*	J:98797 Gersdorff N, Muller M, Otto S, Poschadel R, Hubner S, Miosge N, Basement membrane composition in the early mouse embryo day 7. Dev Dyn. 2005 May 13;233(3):1140-1148
1	J:331476 Hazra R, Brine L, Garcia L, Benz B, Chirathivat N, Shen MM, Wilkinson JE, Lyons SK, Spector DL, Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment. Dev Cell. 2022 Nov 7;57(21):2450-2468.e7
12	J:316440 Imanishi H, Tsuruta D, Tateishi C, Sugawara K, Kobayashi H, Ishii M, Kishi K, Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis. Med Mol Morphol. 2014 Mar;47(1):38-42
4	J:60126 Kadoya Y, Yamashina S, Localization of laminin-5, HD1/plectin, and BP230 in the submandibular glands of developing and adult mice. Histochem Cell Biol. 1999 Dec;112(6):417-25
1	J:185210 Kiyozumi D, Takeichi M, Nakano I, Sato Y, Fukuda T, Sekiguchi K, Basement membrane assembly of the integrin alpha8beta1 ligand nephronectin requires Fraser syndrome-associated proteins. J Cell Biol. 2012 May 28;197(5):677-89
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47
4	J:42382 Kuster JE, Guarnieri MH, Ault JG, Flaherty L, Swiatek PJ, IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa. Mamm Genome. 1997 Sep;8(9):673-81
4	J:38223 Lentz SI, Miner JH, Sanes JR, Snider WD, Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons. J Comp Neurol. 1997 Feb 24;378(4):547-61
3	J:187983 Lopez-Escobar B, De Felipe B, Sanchez-Alcazar JA, Sasaki T, Copp AJ, Ybot-Gonzalez P, Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: Implications for regulation of BMP signalling. Dev Dyn. 2012 Nov;241(11):1808-15
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54
1	J:81295 Mill P, Mo R, Fu H, Grachtchouk M, Kim PC, Dlugosz AA, Hui CC, Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes Dev. 2003 Jan 15;17(2):282-94
2	J:32722 Orian-Rousseau V, Aberdam D, Fontao L, Chevalier L, Meneguzzi G, Kedinger M, Simon-Assmann P, Developmental expression of laminin-5 and HD1 in the intestine: epithelial to mesenchymal shift for the laminin gamma-2 chain subunit deposition. Dev Dyn. 1996 May;206(1):12-23
1	J:320380 Patel VN, Pineda DL, Berenstein E, Hauser BR, Choi S, Prochazkova M, Zheng C, Goldsmith CM, van Kuppevelt TH, Kulkarni A, Song Y, Linhardt RJ, Chibly AM, Hoffman MP, Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function. Matrix Biol. 2021 Sep;103-104:37-57
3	J:44761 Patton BL, Miner JH, Chiu AY, Sanes JR, Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice. J Cell Biol. 1997 Dec 15;139(6):1507-21
1	J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207
4	J:42107 Qin P, Piechocki M, Lu S, Kurpakus MA, Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye. Dev Dyn. 1997 Aug;209(4):367-76
5	J:203643 Radmanesh F, Caglayan AO, Silhavy JL, Yilmaz C, Cantagrel V, Omar T, Rosti B, Kaymakcalan H, Gabriel S, Li M, Sestan N, Bilguvar K, Dobyns WB, Zaki MS, Gunel M, Gleeson JG, Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities. Am J Hum Genet. 2013 Mar 7;92(3):468-74
6*	J:124120 Rebustini IT, Patel VN, Stewart JS, Layvey A, Georges-Labouesse E, Miner JH, Hoffman MP, Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling. Dev Biol. 2007 Aug 1;308(1):15-29
1	J:244304 Richardson R, Mitchell K, Hammond NL, Mollo MR, Kouwenhoven EN, Wyatt ND, Donaldson IJ, Zeef L, Burgis T, Blance R, van Heeringen SJ, Stunnenberg HG, Zhou H, Missero C, Romano RA, Sinha S, Dixon MJ, Dixon J, p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate. PLoS Genet. 2017 Jun;13(6):e1006828
1	J:306807 Saito K, Michon F, Yamada A, Inuzuka H, Yamaguchi S, Fukumoto E, Yoshizaki K, Nakamura T, Arakaki M, Chiba Y, Ishikawa M, Okano H, Thesleff I, Fukumoto S, Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ. iScience. 2020 Jul 24;23(7):101329
2*	J:194131 Sugiyama D, Kulkeaw K, Mizuochi C, TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts. Mech Dev. 2013 Feb;130(2-3):195-206
1*	J:36716 Tajbakhsh S, Rocancourt D, Buckingham M, Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice. Nature. 1996 Nov 21;384(6606):266-70
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
4*	J:23948 Utani A, Kopp JB, Kozak CA, Matsuki Y, Amizuka N, Sugiyama S, Yamada Y, Mouse kalinin B1 (laminin beta 3 chain): cloning and tissue distribution. Lab Invest. 1995 Mar;72(3):300-10
4	J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70
2*	J:96550 Williams TM, Williams ME, Kuick R, Misek D, McDonagh K, Hanash S, Innis JW, Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability. Dev Biol. 2005 Mar 15;279(2):462-80
13	J:45691 Yoshiba K, Yoshiba N, Aberdam D, Meneguzzi G, Perrin-Schmitt F, Stoetzel C, Ruch JV, Lesot H, Expression and localization of laminin-5 subunits during mouse tooth development. Dev Dyn. 1998 Feb;211(2):164-76
10*	J:63373 Yoshiba K, Yoshiba N, Aberdam D, Meneguzzi G, Perrin-Schmitt F, Stoetzel C, Ruch JV, Lesot H, Differential expression of laminin-5 subunits during incisor and molar development in the mouse. Int J Dev Biol. 2000 Apr;44(3):337-40
3	J:47224 Yoshiba N, Yoshiba K, Aberdam D, Meneguzzi G, Perrin-Schmitt F, Stoetzel C, Ruch JV, Lesot H, Expression and localization of laminin-5 subunits in the mouse incisor. Cell Tissue Res. 1998 Apr;292(1):143-9