Gene Expression Literature Summary

• Symbol: Ryr2
• Name: ryanodine receptor 2, cardiac
• ID: MGI:99685

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E5.5	E6.5	E7.5	E8.5	E9.5	E10.5	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15.5	E16.5	E17.5	E18	E18.5	E19.5	E	A
In situ protein (section)									1		1										1
In situ RNA (section)	1	1	1	1	1	1			1		1		1	1	1						1
In situ protein (whole mount)														1	1	1		1			1
In situ RNA (whole mount)														1
Northern blot									1												1
Western blot							1				1				1		1	1			4
RT-PCR			1	1		1	2	1	1	1	2	1	2		2	1		3	1	1	6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ryr2  ryanodine receptor 2, cardiac   (Synonyms: 9330127I20Rik)
Results	Reference
2*	J:45244 Bertocchini F, Ovitt CE, Conti A, Barone V, Scholer HR, Bottinelli R, Reggiani C, Sorrentino V, Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles. EMBO J. 1997 Dec 1;16(23):6956-63
1	J:136876 Buj-Bello A, Fougerousse F, Schwab Y, Messaddeq N, Spehner D, Pierson CR, Durand M, Kretz C, Danos O, Douar AM, Beggs AH, Schultz P, Montus M, Denefle P, Mandel JL, AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis. Hum Mol Genet. 2008 Jul 15;17(14):2132-43
2	J:187997 Chamberlain CM, Ranum LP, Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise. Hum Mol Genet. 2012 Nov 1;21(21):4645-54
3*	J:88432 Ding JH, Xu X, Yang D, Chu PH, Dalton ND, Ye Z, Yeakley JM, Cheng H, Xiao RP, Ross J, Chen J, Fu XD, Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J. 2004 Feb 25;23(4):885-96
12	J:79406 Faure AV, Grunwald D, Moutin MJ, Hilly M, Mauger JP, Marty I, De Waard M, Villaz M, Albrieux M, Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex. Eur J Neurosci. 2001 Nov;14(10):1613-22
2	J:149480 Feng Y, Valley MT, Lazar J, Yang AL, Bronson RT, Firestein S, Coetzee WA, Manley JL, SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart. Dev Cell. 2009 Apr;16(4):528-38
1*	J:171409 GUDMAP: the GenitoUrinary Development Molecular Anatomy Project, http://www.gudmap.org. 2004;
2*	J:119550 Harrell MD, Harbi S, Hoffman JF, Zavadil J, Coetzee WA, Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Physiol Genomics. 2007 Feb 12;28(3):273-83
8*	J:97586 Hong S, Kim TW, Choi I, Woo JM, Oh J, Park WJ, Kim do H, Cho C, Complementary DNA cloning, genomic characterization and expression analysis of a mammalian gene encoding histidine-rich calcium binding protein. Biochim Biophys Acta. 2005 Mar 10;1727(3):188-96
1*	J:86837 Kuwahara K, Saito Y, Takano M, Arai Y, Yasuno S, Nakagawa Y, Takahashi N, Adachi Y, Takemura G, Horie M, Miyamoto Y, Morisaki T, Kuratomi S, Noma A, Fujiwara H, Yoshimasa Y, Kinoshita H, Kawakami R, Kishimoto I, Nakanishi M, Usami S, Saito Y, Harada M, Nakao K, NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function. EMBO J. 2003 Dec 1;22(23):6310-21
1*	J:106344 Matalon R, Surendran S, McDonald JD, Okorodudu AO, Tyring SK, Michals-Matalon K, Harris P, Abnormal expression of genes associated with development and inflammation in the heart of mouse maternal phenylketonuria offspring. Int J Immunopathol Pharmacol. 2005 Jul-Sep;18(3):557-65
3	J:63370 Mori F, Fukaya M, Abe H, Wakabayashi K, Watanabe M, Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain. Neurosci Lett. 2000 May 5;285(1):57-60
11	J:53109 Rosemblit N, Moschella MC, Ondriasa E, Gutstein DE, Ondrias K, Marks AR, Intracellular calcium release channel expression during embryogenesis. Dev Biol. 1999 Feb 15;206(2):163-77
4	J:112566 Stolk M, Leon-Ponte M, Merrill M, Ahern GP, O'Connell PJ, IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1. J Leukoc Biol. 2006 Sep;80(3):651-8
5	J:72636 Takekura H, Flucher BE, Franzini-Armstrong C, Sequential Docking, Molecular Differentiation, and Positioning of T-Tubule/SR Junctions in Developing Mouse Skeletal Muscle. Dev Biol. 2001 Nov 15;239(2):204-14
1	J:142482 Yin Z, Jones GN, Towns WH 2nd, Zhang X, Abel ED, Binkley PF, Jarjoura D, Kirschner LS, Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis. Circulation. 2008 Mar 18;117(11):1414-22