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Gene Expression Literature Summary
Symbol
Name
ID
S1pr2
sphingosine-1-phosphate receptor 2
MGI:99569

19 matching records from 19 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7.5 E8.5 E9.5 E10.5 E11.5 E12.5 E13.5 E14 E14.5 E15.5 E16.5 E17.5 E P
Immunohistochemistry (section) 1 1
In situ RNA (section) 2 2 1 1 1 2 1 1 1 2
In situ RNA (whole mount) 2 2 2 1 1 1
Northern blot 1 1 1 5
RT-PCR 1 1 2 3 3 3 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
S1pr2  sphingosine-1-phosphate receptor 2   (Synonyms: 1100001A16Rik, Edg5, Gpcr13, H218, LPb2, S1P2)
Results  Reference
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2*J:97177 Edsbagge J, Johansson JK, Esni F, Luo Y, Radice GL, Semb H, Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme. Development. 2005 Mar;132(5):1085-92
1J:140104 Franco CA, Mericskay M, Parlakian A, Gary-Bobo G, Gao-Li J, Paulin D, Gustafsson E, Li Z, Serum response factor is required for sprouting angiogenesis and vascular integrity. Dev Cell. 2008 Sep;15(3):448-61
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
1J:71372 Ishii I, Friedman B, Ye X, Kawamura S, McGiffert C, Contos JJ, Kingsbury MA, Zhang G, Heller Brown J, Chun J, Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3. J Biol Chem. 2001 Sep 7;276(36):33697-704
1J:166492 Itoh R, Miura S, Takimoto A, Kondo S, Sano H, Hiraki Y, Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells. J Bone Miner Metab. 2010 Nov;28(6):659-71
2J:145748 Kirby RJ, Jin Y, Fu J, Cubillos J, Swertfeger D, Arend LJ, Dynamic regulation of sphingosine-1-phosphate homeostasis during development of mouse metanephric kidney. Am J Physiol Renal Physiol. 2009 Mar;296(3):F634-41
1J:106055 Kono M, Mi Y, Liu Y, Sasaki T, Allende ML, Wu YP, Yamashita T, Proia RL, The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis. J Biol Chem. 2004 Jul 9;279(28):29367-73
1J:169062 Lopez-Juarez A, Morales-Lazaro S, Sanchez-Sanchez R, Sunkara M, Lomeli H, Velasco I, Morris AJ, Escalante-Alcalde D, Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development. Glia. 2011 Apr;59(4):577-89
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
5J:79922 McGiffert C, Contos JJ, Friedman B, Chun J, Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis. FEBS Lett. 2002 Oct 30;531(1):103-8
9J:144181 Meng H, Lee VM, Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system. Dev Dyn. 2009 Feb;238(2):487-500
1J:103755 Mizugishi K, Yamashita T, Olivera A, Miller GF, Spiegel S, Proia RL, Essential role for sphingosine kinases in neural and vascular development. Mol Cell Biol. 2005 Dec;25(24):11113-21
2J:217596 Nakajima C, Haffner P, Goerke SM, Zurhove K, Adelmann G, Frotscher M, Herz J, Bock HH, May P, The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development. Development. 2014 Dec;141(23):4513-25
5*J:140656 Ohuchi H, Hamada A, Matsuda H, Takagi A, Tanaka M, Aoki J, Arai H, Noji S, Expression patterns of the lysophospholipid receptor genes during mouse early development. Dev Dyn. 2008 Nov;237(11):3280-94
2J:173601 Poulsen RR, McClaskey CM, Rivkees SA, Wendler CC, The Sphingosine-1-phospate receptor 1 mediates S1P action during cardiac development. BMC Dev Biol. 2011;11:37
1J:171472 Sand FW, Hornblad A, Johansson JK, Loren C, Edsbagge J, Stahlberg A, Magenheim J, Ilovich O, Mishani E, Dor Y, Ahlgren U, Semb H, Growth-limiting role of endothelial cells in endoderm development. Dev Biol. 2011 Apr 15;352(2):267-77
6*J:107068 Wendler CC, Rivkees SA, Sphingosine-1-phosphate inhibits cell migration and endothelial to mesenchymal cell transformation during cardiac development. Dev Biol. 2006 Mar 15;291(2):264-77
2J:52870 Zhang G, Contos JJ, Weiner JA, Fukushima N, Chun J, Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate. Gene. 1999 Feb 4;227(1):89-99

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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory