About   Help   FAQ
Gene Expression Literature Summary
Symbol
Name
ID
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
MGI:99400

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1 E2 E2.5 E3 E3.5 E4 E9 E9.5 E10.5 E11.5 E13.5 E14.5 E15 E15.5 E17 E17.5 E18.5 E19 E A
In situ RNA (section) 1 1 1 1 1 1 1 1 1
In situ RNA (whole mount) 1 1 1
Northern blot 1 1 1 1 2 1 2 4
Western blot 1
RT-PCR 1 1 1 3
cDNA clones 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Atp7a  ATPase, Cu++ transporting, alpha polypeptide   (Synonyms: br, Menkes protein, MNK)
Results  Reference
1J:153556 Colasante G, Sessa A, Crispi S, Calogero R, Mansouri A, Collombat P, Broccoli V, Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity. Dev Biol. 2009 Oct 1;334(1):59-71
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4J:150959 Kalantry S, Purushothaman S, Bowen RB, Starmer J, Magnuson T, Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation. Nature. 2009 Jul 30;460(7255):647-51
9J:41389 Kuo YM, Gitschier J, Packman S, Developmental expression of the mouse mottled and toxic milk genes suggests distinct functions for the Menkes and Wilson disease copper transporters. Hum Mol Genet. 1997 Jul;6(7):1043-9
3J:157314 Ling KH, Hewitt CA, Beissbarth T, Hyde L, Banerjee K, Cheah PS, Cannon PZ, Hahn CN, Thomas PQ, Smyth GK, Tan SS, Thomas T, Scott HS, Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. Genome Biol. 2009;10(10):R104
4*J:17493 Mercer JF, Grimes A, Ambrosini L, Lockhart P, Paynter JA, Dierick H, Glover TW, Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice [see comments]. Nat Genet. 1994 Apr;6(4):374-8
2J:105797 Mototani Y, Miyoshi I, Okamura T, Moriya T, Meng Y, Yuan Pei X, Kameo S, Kasai N, Phenotypic and genetic characterization of the Atp7a(Mo-Tohm) mottled mouse: a new murine model of Menkes disease. Genomics. 2006 Feb;87(2):191-9
1J:185555 Mugford JW, Yee D, Magnuson T, Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation. Development. 2012 Jun;139(12):2130-8
2J:46349 Ohta Y, Shiraishi N, Nishikimi M, Occurrence of two missense mutations in Cu-ATpase of the macular mouse, a menkes disease model. Biochem Mol Biol Int. 1997 NOV;43(4):913-918
3*J:20585 Paynter JA, Grimes A, Lockhart P, Mercer JF, Expression of the Menkes gene homologue in mouse tissues lack of effect of copper on the mRNA levels. FEBS Lett. 1994 Sep 5;351(2):186-90
1J:189931 Wang Y, Zhu S, Weisman GA, Gitlin JD, Petris MJ, Conditional knockout of the Menkes disease copper transporter demonstrates its critical role in embryogenesis. PLoS One. 2012;7(8):e43039
3J:171449 Williams LH, Kalantry S, Starmer J, Magnuson T, Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass. Development. 2011 May;138(10):2049-57

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/12/2014
MGI 5.19
The Jackson Laboratory