Gene Expression Literature Summary

• Symbol: Tyr
• Name: tyrosinase
• ID: MGI:98880

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10.5	E11	E11.5	E12	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	E	A
In situ protein (section)			1	2	1	1					2			1
In situ RNA (section)	1	2		3		3	2	4	1	1	2	2	1	2
In situ RNA (whole mount)		1		3	1	1	1
Western blot				1		1	1	1	1			1
RT-PCR												1		3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tyr  tyrosinase   (Synonyms: skc35)
Results	Reference
6	J:25 Beermann F, Schmid E, Schutz G, Expression of the mouse tyrosinase gene during embryonic development: recapitulation of the temporal regulation in transgenic mice. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2809-13
1	J:188155 Bharti K, Gasper M, Ou J, Brucato M, Clore-Gronenborn K, Pickel J, Arnheiter H, A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet. 2012 Jul;8(7):e1002757
2	J:132153 Bharti K, Liu W, Csermely T, Bertuzzi S, Arnheiter H, Alternative promoter use in eye development: the complex role and regulation of the transcription factor MITF. Development. 2008 Mar;135(6):1169-78
1	J:194534 Chang CY, Pasolli HA, Giannopoulou EG, Guasch G, Gronostajski RM, Elemento O, Fuchs E, NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. Nature. 2013 Mar 7;495(7439):98-102
1	J:178952 Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, Rank G, Srivastava S, Finlay MJ, Papenfuss AT, Pandolfi PP, Pearson RB, Jane SM, Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell. 2011 Nov 15;20(5):635-48
10	J:89665 Gimenez E, Lavado A, Giraldo P, Montoliu L, Tyrosinase gene expression is not detected in mouse brain outside the retinal pigment epithelium cells. Eur J Neurosci. 2003 Nov;18(9):2673-6
2	J:94374 Horsford DJ, Nguyen MT, Sellar GC, Kothary R, Arnheiter H, McInnes RR, Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity. Development. 2005 Jan;132(1):177-87
1	J:101313 Lanning JL, Wallace JS, Zhang D, Diwakar G, Jiao Z, Hornyak TJ, Altered melanocyte differentiation and retinal pigmented epithelium transdifferentiation induced by Mash1 expression in pigment cell precursors. J Invest Dermatol. 2005 Oct;125(4):805-17
1	J:154593 Levin MD, Lu MM, Petrenko NB, Hawkins BJ, Gupta TH, Lang D, Buckley PT, Jochems J, Liu F, Spurney CF, Yuan LJ, Jacobson JT, Brown CB, Huang L, Beermann F, Margulies KB, Madesh M, Eberwine JH, Epstein JA, Patel VV, Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers. J Clin Invest. 2009 Nov;119(11):3420-36
1*	J:157352 Loftus SK, Baxter LL, Buac K, Watkins-Chow DE, Larson DM, Pavan WJ, Comparison of melanoblast expression patterns identifies distinct classes of genes. Pigment Cell Melanoma Res. 2009 Oct;22(5):611-22
1*	J:75774 Loftus SK, Larson DM, Baxter LL, Antonellis A, Chen Y, Wu X, Jiang Y, Bittner M, Hammer JA 3rd, Pavan WJ, Mutation of melanosome protein RAB38 in chocolate mice. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4471-6
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:69855 Martinez-Morales JR, Signore M, Acampora D, Simeone A, Bovolenta P, Otx genes are required for tissue specification in the developing eye. Development. 2001 Jun;128(11):2019-30
1	J:46130 Nakayama A, Nguyen MT, Chen CC, Opdecamp K, Hodgkinson CA, Arnheiter H, Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech Dev. 1998 Jan;70(1-2):155-66
2*	J:93571 Rowan S, Chen CM, Young TL, Fisher DE, Cepko CL, Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development. 2004 Oct;131(20):5139-52
6	J:65992 Surace EM, Angeletti B, Ballabio A, Marigo V, Expression pattern of the ocular albinism type 1 (Oa1) gene in the murine retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2000 Dec;41(13):4333-7
8	J:32249 Tief K, Schmidt A, Aguzzi A, Beermann F, Tyrosinase is a new marker for cell populations in the mouse neural tube. Dev Dyn. 1996 Apr;205(4):445-56
1	J:178818 Wang B, Harrison W, Overbeek PA, Zheng H, Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development. 2011 Oct;138(20):4487-97