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Gene Expression Literature Summary
Symbol
Name
ID
Ttr
transthyretin
MGI:98865

77 matching records from 77 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E5.5 E6.5 E7.5 E8 E8.5 E9 E9.5 E10 E10.5 E11.5 E12.5 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19.5 E A
In situ protein (section) 1 1 1 1 1 1 1 1
In situ RNA (section) 1 2 2 3 1 1 1 7 18 3 1 11 5 1 2 3 1 1 2 10
In situ RNA (whole mount) 1 3 2 2 3 2 5 4 6 2 1 1 1 2
Northern blot 1 1 1 1 1 1 4
RT-PCR 1 1 2 3 1 1 2 2 1 2 1 3 1 1 2 1 6
cDNA clones 1 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Ttr  transthyretin   (Synonyms: prealbumin)
Results  Reference
2J:152710 Aldinger KA, Lehmann OJ, Hudgins L, Chizhikov VV, Bassuk AG, Ades LC, Krantz ID, Dobyns WB, Millen KJ, FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation. Nat Genet. 2009 Sep;41(9):1037-42
3*J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1J:87725 Bort R, Martinez-Barbera JP, Beddington RS, Zaret KS, Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas. Development. 2004 Feb;131(4):797-806
1J:106993 Briancon N, Weiss MC, In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping. EMBO J. 2006 Mar 22;25(6):1253-62
1J:31593 Cereghini S, Ott MO, Power S, Maury M, Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles. Development. 1992 Nov;116(3):783-97
3J:91504 Charalambous M, Menheniott TR, Bennett WR, Kelly SM, Dell G, Dandolo L, Ward A, An enhancer element at the Igf2/H19 locus drives gene expression in both imprinted and non-imprinted tissues. Dev Biol. 2004 Jul 15;271(2):488-97
1*J:58080 Coffinier C, Thepot D, Babinet C, Yaniv M, Barra J, Essential role for the homeoprotein vHNF1/HNF1beta in visceral endoderm differentiation. Development. 1999 Nov;126(21):4785-94
1*J:152211 Coulpier F, Le Crom S, Maro GS, Manent J, Giovannini M, Maciorowski Z, Fischer A, Gessler M, Charnay P, Topilko P, Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. Glia. 2009 Oct;57(13):1450-7
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3J:197462 Dillman AA, Hauser DN, Gibbs JR, Nalls MA, McCoy MK, Rudenko IN, Galter D, Cookson MR, mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex. Nat Neurosci. 2013 Apr;16(4):499-506
1J:39656 Farrington SM, Belaoussoff M, Baron MH, Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac. Mech Dev. 1997 Mar;62(2):197-211
2J:136720 Friedrichs M, Larralde O, Skutella T, Theil T, Lamination of the cerebral cortex is disturbed in Gli3 mutant mice. Dev Biol. 2008 Jun 1;318(1):203-14
1*J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44
6J:139139 Garcia-Garcia MJ, Shibata M, Anderson KV, Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo. Development. 2008 Sep;135(18):3053-62
1J:140315 Geng X, Speirs C, Lagutin O, Inbal A, Liu W, Solnica-Krezel L, Jeong Y, Epstein DJ, Oliver G, Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev Cell. 2008 Aug;15(2):236-47
2J:171615 Georgas KM, Chiu HS, Lesieur E, Rumballe BA, Little MH, Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Dev Dyn. 2011 Jun;240(6):1600-12
1J:102085 Grove EA, Tole S, Patterning events and specification signals in the developing hippocampus. Cereb Cortex. 1999 Sep;9(6):551-61
4*J:48569 Grove EA, Tole S, Limon J, Yip L, Ragsdale CW, The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice. Development. 1998 Jun;125(12):2315-25
6*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
1*J:84414 Haraguchi S, Tsuda M, Kitajima S, Sasaoka Y, Nomura-Kitabayashid A, Kurokawa K, Saga Y, nanos1: a mouse nanos gene expressed in the central nervous system is dispensable for normal development. Mech Dev. 2003 Jun;120(6):721-31
8J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90
1J:83123 Hebert JM, Hayhurst M, Marks ME, Kulessa H, Hogan BL, McConnell SK, BMP ligands act redundantly to pattern the dorsal telencephalic midline. Genesis. 2003 Apr;35(4):214-9
2J:79021 Hebert JM, Mishina Y, McConnell SK, BMP signaling is required locally to pattern the dorsal telencephalic midline. Neuron. 2002 Sep 12;35(6):1029-41
1J:31553 Hentsch B, Lyons I, Li R, Hartley L, Lints TJ, Adams JM, Harvey RP, Hlx homeo box gene is essential for an inductive tissue interaction that drives expansion of embryonic liver and gut. Genes Dev. 1996 Jan 1;10(1):70-9
1*J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
6*J:125749 Hou J, Charters AM, Lee SC, Zhao Y, Wu MK, Jones SJ, Marra MA, Hoodless PA, A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE). BMC Dev Biol. 2007;7:92
1J:152851 Huang X, Ketova T, Fleming JT, Wang H, Dey SK, Litingtung Y, Chiang C, Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus. Development. 2009 Aug;136(15):2535-43
2J:125109 Huang X, Litingtung Y, Chiang C, Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly. Hum Mol Genet. 2007 Jun 15;16(12):1454-68
3J:127999 Hunter NL, Dymecki SM, Molecularly and temporally separable lineages form the hindbrain roof plate and contribute differentially to the choroid plexus. Development. 2007 Oct;134(19):3449-60
4J:139170 Imayoshi I, Shimogori T, Ohtsuka T, Kageyama R, Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development. 2008 Aug;135(15):2531-41
1J:121744 Inoue T, Ota M, Ogawa M, Mikoshiba K, Aruga J, Zic1 and Zic3 regulate medial forebrain development through expansion of neuronal progenitors. J Neurosci. 2007 May 16;27(20):5461-73
4*J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27
4J:143555 Jiang B, Kumar SD, Loh WT, Manikandan J, Ling EA, Tay SS, Dheen ST, Global gene expression analysis of cranial neural tubes in embryos of diabetic mice. J Neurosci Res. 2008 Dec;86(16):3481-93
4J:187010 Jiang X, Zhou Y, Xian L, Chen W, Wu H, Gao X, The mutation in chd7 causes misexpression of bmp4 and developmental defects in telencephalic midline. Am J Pathol. 2012 Aug;181(2):626-41
1J:194049 Johansson PA, Irmler M, Acampora D, Beckers J, Simeone A, Gotz M, The transcription factor Otx2 regulates choroid plexus development and function. Development. 2013 Mar;140(5):1055-66
1J:53312 Kaestner KH, Katz J, Liu Y, Drucker DJ, Schutz G, Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo. Genes Dev. 1999 Feb 15;13(4):495-504
1J:65105 Keng VW, Yagi H, Ikawa M, Nagano T, Myint Z, Yamada K, Tanaka T, Sato A, Muramatsu I, Okabe M, Sato M, Noguchi T, Homeobox gene hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage. Biochem Biophys Res Commun. 2000 Oct 5;276(3):1155-61
2J:70278 Kimura C, Shen MM, Takeda N, Aizawa S, Matsuo I, Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast. Dev Biol. 2001 Jul 1;235(1):12-32
1J:98539 Kimura J, Suda Y, Kurokawa D, Hossain ZM, Nakamura M, Takahashi M, Hara A, Aizawa S, Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium. J Neurosci. 2005 May 25;25(21):5097-108
1J:203109 Konno D, Iwashita M, Satoh Y, Momiyama A, Abe T, Kiyonari H, Matsuzaki F, The mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortex. PLoS One. 2012;7(10):e46577
4J:150863 Kwon GS, Hadjantonakis AK, Transthyretin mouse transgenes direct RFP expression or Cre-mediated recombination throughout the visceral endoderm. Genesis. 2009 Jul;47(7):447-55
2J:197131 Lanctot AA, Peng CY, Pawlisz AS, Joksimovic M, Feng Y, Spatially dependent dynamic MAPK modulation by the nde1-lis1-brap complex patterns Mammalian CNS. Dev Cell. 2013 May 13;25(3):241-55
1J:178674 Lavado A, Oliver G, Six3 is required for ependymal cell maturation. Development. 2011 Dec;138(24):5291-300
2*J:94197 Long L, Spear BT, FoxA proteins regulate H19 endoderm enhancer E1 and exhibit developmental changes in enhancer binding in vivo. Mol Cell Biol. 2004 Nov;24(21):9601-9
1*J:85727 Louvi A, Alexandre P, Metin C, Wurst W, Wassef M, The isthmic neuroepithelium is essential for cerebellar midline fusion. Development. 2003 Nov;130(22):5319-30
6J:64091 Louvi A, Wassef M, Ectopic engrailed 1 expression in the dorsal midline causes cell death, abnormal differentiation of circumventricular organs and errors in axonal pathfinding. Development. 2000 Sep;127(18):4061-71
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1J:73082 Monuki ES, Porter FD, Walsh CA, Patterning of the dorsal telencephalon and cerebral cortex by a roof plate-lhx2 pathway. Neuron. 2001 Nov 20;32(4):591-604
5*J:94249 Murakami T, Yasuda Y, Mita S, Maeda S, Shimada K, Fujimoto T, Araki S, Prealbumin gene expression during mouse development studied by in situ hybridization. Cell Differ. 1987 Nov;22(1):1-9
1J:78037 Muzio L, DiBenedetto B, Stoykova A, Boncinelli E, Gruss P, Mallamaci A, Conversion of cerebral cortex into basal ganglia in Emx2(-/-) Pax6(Sey/Sey) double-mutant mice. Nat Neurosci. 2002 Aug;5(8):737-45
2J:98698 Muzio L, Mallamaci A, Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium. J Neurosci. 2005 Apr 27;25(17):4435-41
2J:65651 Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG, Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Mech Dev. 2000 Nov;98(1-2):77-94
3*J:75776 Nicolas G, Bennoun M, Porteu A, Mativet S, Beaumont C, Grandchamp B, Sirito M, Sawadogo M, Kahn A, Vaulont S, Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4596-601
3J:160263 Nielsen CM, Dymecki SM, Sonic hedgehog is required for vascular outgrowth in the hindbrain choroid plexus. Dev Biol. 2010 Apr 15;340(2):430-7
1J:150347 Paek H, Gutin G, Hebert JM, FGF signaling is strictly required to maintain early telencephalic precursor cell survival. Development. 2009 Jul;136(14):2457-65
1J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22
1J:45334 Rausa F, Samadani U, Ye H, Lim L, Fletcher CF, Jenkins NA, Copeland NG, Costa RH, The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3 beta in the developing murine liver and pancreas. Dev Biol. 1997 Dec 15;192(2):228-46
1J:50836 Rausa FM, Ye H, Lim L, Duncan SA, Costa RH, In situ hybridization with 33P-labeled RNA probes for determination of cellular expression patterns of liver transcription factors in mouse embryos [published erratum appears in Methods 1998 Nov;16(3):359-60]. Methods. 1998 Sep;16(1):29-41
2J:59916 Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, Zhang J, Horton HF, Scott A, Orkin SH, Byrne MC, Grusby MJ, Glimcher LH, An essential role in liver development for transcription factor XBP-1. Genes Dev. 2000 Jan 15;14(2):152-7
2J:199892 Rhee S, Guerrero-Zayas MI, Wallingford MC, Ortiz-Pineda P, Mager J, Tremblay KD, Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development. PLoS One. 2013;8(3):e58828
1J:166617 Sakurai Y, Kurokawa D, Kiyonari H, Kajikawa E, Suda Y, Aizawa S, Otx2 and Otx1 protect diencephalon and mesencephalon from caudalization into metencephalon during early brain regionalization. Dev Biol. 2010 Nov 15;347(2):392-403
2J:178936 Shibata M, Blauvelt KE, Liem KF Jr, Garcia-Garcia MJ, TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues. Development. 2011 Dec;138(24):5333-43
1J:168015 Shibata M, Garcia-Garcia MJ, The mouse KRAB zinc-finger protein CHATO is required in embryonic-derived tissues to control yolk sac and placenta morphogenesis. Dev Biol. 2011 Jan 15;349(2):331-41
2J:141122 Shibata M, Kurokawa D, Nakao H, Ohmura T, Aizawa S, MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium. J Neurosci. 2008 Oct 8;28(41):10415-21
2*J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
2*J:90405 Shinozaki K, Yoshida M, Nakamura M, Aizawa S, Suda Y, Emx1 and Emx2 cooperate in initial phase of archipallium development. Mech Dev. 2004 May;121(5):475-89
1J:163670 Spruce T, Pernaute B, Di-Gregorio A, Cobb BS, Merkenschlager M, Manzanares M, Rodriguez TA, An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo. Dev Cell. 2010 Aug 17;19(2):207-19
1J:171680 Stuckey DW, Di Gregorio A, Clements M, Rodriguez TA, Correct patterning of the primitive streak requires the anterior visceral endoderm. PLoS One. 2011;6(3):e17620
4J:105760 Swetloff A, Ferretti P, Changes in E2F5 intracellular localization in mouse and human choroid plexus epithelium with development. Int J Dev Biol. 2005;49(7):859-65
2J:171050 Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH, Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
3*J:31471 Thomas T, Dziadek M, Capacity to form choroid plexus-like cells in vitro is restricted to specific regions of the mouse neural ectoderm. Development. 1993 Jan;117(1):253-62
1*J:72659 Tole S, Goudreau G, Assimacopoulos S, Grove EA, Emx2 is required for growth of the hippocampus but not for hippocampal field specification. J Neurosci. 2000 Apr 1;20(7):2618-25
2J:137798 Tomizawa M, Toyama Y, Ito C, Toshimori K, Iwase K, Takiguchi M, Saisho H, Yokosuka O, Hepatoblast-like cells enriched from mouse embryonic stem cells in medium without glucose, pyruvate, arginine, and tyrosine. Cell Tissue Res. 2008 Jul;333(1):17-27
3J:146397 Wanderling S, Simen BB, Ostrovsky O, Ahmed NT, Vogen SM, Gidalevitz T, Argon Y, GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion. Mol Biol Cell. 2007 Oct;18(10):3764-75
1J:142500 Willaredt MA, Hasenpusch-Theil K, Gardner HA, Kitanovic I, Hirschfeld-Warneken VC, Gojak CP, Gorgas K, Bradford CL, Spatz J, Wolfl S, Theil T, Tucker KL, A crucial role for primary cilia in cortical morphogenesis. J Neurosci. 2008 Nov 26;28(48):12887-900
1J:103454 Woda JM, Calzonetti T, Hilditch-Maguire P, Duyao MP, Conlon RA, MacDonald ME, Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo. BMC Dev Biol. 2005 Aug 18;5:17
1J:97579 Zhao R, Watt AJ, Li J, Luebke-Wheeler J, Morrisey EE, Duncan SA, GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol Cell Biol. 2005 Apr;25(7):2622-31

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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory