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Gene Expression Literature Summary
Symbol
Name
ID
Pgk1
phosphoglycerate kinase 1
MGI:97555

42 matching records from 42 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1 E2 E2.5 E3 E3.5 E4 E6 E6.5 E7 E7.5 E8.5 E9.5 E10.5 E11 E11.5 E12 E12.5 E13.5 E14 E14.5 E15.5 E16.5 E17.5 E18.5 E19 E A
In situ protein (section) 2 1
In situ RNA (section) 1 1 1 1 1 2 2 1 2 2 5 1 1 1 1
In situ RNA (whole mount) 2 1 1
Northern blot 1 1 1 1 1
Western blot 1 1 1 2
RT-PCR 1 1 1 1 4 5 2 1 1 3 1 1 2 1 1 1 10
Primer Extension 1 1 1 1 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pgk1  phosphoglycerate kinase 1   (Synonyms: Pgk-1)
Results  Reference
1J:126336 Amarilio R, Viukov SV, Sharir A, Eshkar-Oren I, Johnson RS, Zelzer E, HIF1{alpha} regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeletogenesis. Development. 2007 Nov;134(21):3917-28
2J:142334 Blewitt ME, Gendrel AV, Pang Z, Sparrow DB, Whitelaw N, Craig JM, Apedaile A, Hilton DJ, Dunwoodie SL, Brockdorff N, Kay GF, Whitelaw E, SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation. Nat Genet. 2008 May;40(5):663-9
2J:144610 Boda E, Pini A, Hoxha E, Parolisi R, Tempia F, Selection of Reference Genes for Quantitative Real-time RT-PCR Studies in Mouse Brain. J Mol Neurosci. 2009 Mar;37(3):238-53
2J:21784 Buzin CH, Mann JR, Singer-Sam J, Quantitative RT-PCR assays show Xist RNA levels are low in mouse female adult tissue, embryos and embryoid bodies. Development. 1994 Dec;120(12):3529-36
3*J:18259 Campos RV, Lee YC, Drucker DJ, Divergent tissue-specific and developmental expression of receptors for glucagon and glucagon-like peptide-1 in the mouse. Endocrinology. 1994 May;134(5):2156-64
1*J:125993 Cankaya M, Hernandez AM, Ciftci M, Beydemir S, Ozdemir H, Budak H, Gulcin I, Comakli V, Emircupani T, Ekinci D, Kuzu M, Jiang Q, Eichele G, Kufrevioglu OI, An analysis of expression patterns of genes encoding proteins with catalytic activities. BMC Genomics. 2007;8:232
2J:182738 Chhabra A, Lechner AJ, Ueno M, Acharya A, Van Handel B, Wang Y, Iruela-Arispe ML, Tallquist MD, Mikkola HK, Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling. Dev Cell. 2012 Mar 13;22(3):651-9
2J:105812 Covello KL, Kehler J, Yu H, Gordan JD, Arsham AM, Hu CJ, Labosky PA, Simon MC, Keith B, HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev. 2006 Mar 1;20(5):557-70
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:204566 Gendrel AV, Tang YA, Suzuki M, Godwin J, Nesterova TB, Greally JM, Heard E, Brockdorff N, Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
1J:78912 Hellstrom M, Gerhardt H, Kalen M, Li X, Eriksson U, Wolburg H, Betsholtz C, Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001 Apr 30;153(3):543-53
1J:170943 Holscher M, Silter M, Krull S, von Ahlen M, Hesse A, Schwartz P, Wielockx B, Breier G, Katschinski DM, Zieseniss A, Cardiomyocyte-specific Prolyl-4-hydroxylase Domain 2 Knock Out Protects from Acute Myocardial Ischemic Injury. J Biol Chem. 2011 Apr 1;286(13):11185-94
11J:134647 Honda JY, Kobayashi I, Kiyoshima T, Yamaza H, Xie M, Takahashi K, Enoki N, Nagata K, Nakashima A, Sakai H, Glycolytic enzyme Pgk1 is strongly expressed in the developing tooth germ of the mouse lower first molar. Histol Histopathol. 2008 Apr;23(4):423-32
1*J:93871 Huang J, Fan T, Yan Q, Zhu H, Fox S, Issaq HJ, Best L, Gangi L, Munroe D, Muegge K, Lsh, an epigenetic guardian of repetitive elements. Nucleic Acids Res. 2004;32(17):5019-28
1J:162597 Hyvarinen J, Hassinen IE, Sormunen R, Maki JM, Kivirikko KI, Koivunen P, Myllyharju J, Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury. J Biol Chem. 2010 Apr 30;285(18):13646-57
1J:115851 Kalantry S, Magnuson T, The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation. PLoS Genet. 2006 May;2(5):e66
4J:150959 Kalantry S, Purushothaman S, Bowen RB, Starmer J, Magnuson T, Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation. Nature. 2009 Jul 30;460(7255):647-51
2J:69874 Keith B, Adelman DM, Simon MC, Targeted mutation of the murine arylhydrocarbon receptor nuclear translocator 2 (Arnt2) gene reveals partial redundancy with Arnt. Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6692-7
1*J:154369 Lanier J, Dykes IM, Nissen S, Eng SR, Turner EE, Brn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglion. Dev Dyn. 2009 Oct 29;238(12):3065-3079
1J:194283 Liu J, Li Q, Kuehn MR, Litingtung Y, Vokes SA, Chiang C, Sonic hedgehog signaling directly targets Hyaluronic Acid Synthase 2, an essential regulator of phalangeal joint patterning. Dev Biol. 2013 Mar 15;375(2):160-71
1J:38094 Marahrens Y, Panning B, Dausman J, Strauss W, Jaenisch R, Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes Dev. 1997 JAN 15;11(2):156-166
1J:185555 Mugford JW, Yee D, Magnuson T, Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation. Development. 2012 Jun;139(12):2130-8
3J:96532 Nolen LD, Gao S, Han Z, Mann MR, Gie Chung Y, Otte AP, Bartolomei MS, Latham KE, X chromosome reactivation and regulation in cloned embryos. Dev Biol. 2005 Mar 15;279(2):525-40
1J:42759 Panning B, Dausman J, Jaenisch R, X chromosome inactivation is mediated by Xist RNA stabilization. Cell. 1997 Sep 5;90(5):907-16
2J:35056 Panning B, Jaenisch R, DNA hypomethylation can activate Xist expression and silence X-linked genes. Genes Dev. 1996 Aug 15;10(16):1991-2002
3J:32220 Pravtcheva DD, Adra CN, Ruddle FH, Timing of paternal Pgk-1 expression in embryos of transgenic mice. Development. 1991 Apr;111(4):1109-20
1J:110805 Ramirez-Bergeron DL, Runge A, Adelman DM, Gohil M, Simon MC, HIF-dependent hematopoietic factors regulate the development of the embryonic vasculature. Dev Cell. 2006 Jul;11(1):81-92
2J:48084 Ryan HE, Lo J, Johnson RS, HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J. 1998 Jun 1;17(11):3005-15
4J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49
5J:112954 Savarese F, Flahndorfer K, Jaenisch R, Busslinger M, Wutz A, Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation. Mol Cell Biol. 2006 Oct;26(19):7167-77
1J:72709 Schipani E, Ryan HE, Didrickson S, Kobayashi T, Knight M, Johnson RS, Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev. 2001 Nov 1;15(21):2865-76
5J:35235 Sheardown S, Norris D, Fisher A, Brockdorff N, The mouse Smcx gene exhibits developmental and tissue specific variation in degree of escape from X inactivation. Hum Mol Genet. 1996 Sep;5(9):1355-60
1J:185195 Smith LB, Milne L, Nelson N, Eddie S, Brown P, Atanassova N, O'Bryan MK, O'Donnell L, Rhodes D, Wells S, Napper D, Nolan P, Lalanne Z, Cheeseman M, Peters J, KATNAL1 Regulation of Sertoli Cell Microtubule Dynamics Is Essential for Spermiogenesis and Male Fertility. PLoS Genet. 2012 May;8(5):e1002697
3J:53707 Sturm K, Lafferty M, Tam PP, Pgk1 and Hprt gene activity in the peri-implantation mouse embryo is influenced by the parental origin of the X-chromosome. Int J Dev Biol. 1999 Jan;43(1):69-73
1J:114669 Takeda K, Ho VC, Takeda H, Duan LJ, Nagy A, Fong GH, Placental but Not Heart Defects Are Associated with Elevated Hypoxia-Inducible Factor {alpha} Levels in Mice Lacking Prolyl Hydroxylase Domain Protein 2. Mol Cell Biol. 2006 Nov;26(22):8336-46
1J:155773 Tkatchenko TV, Moreno-Rodriguez RA, Conway SJ, Molkentin JD, Markwald RR, Tkatchenko AV, Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. Physiol Genomics. 2009 Nov 6;39(3):160-8
2J:169365 Turner JM, Mahadevaiah SK, Benavente R, Offenberg HH, Heyting C, Burgoyne PS, Analysis of male meiotic 'sex body' proteins during XY female meiosis provides new insights into their functions. Chromosoma. 2000 Sep;109(6):426-32
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2J:188772 Voss AK, Vanyai HK, Collin C, Dixon MP, McLennan TJ, Sheikh BN, Scambler P, Thomas T, MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome. Dev Cell. 2012 Sep 11;23(3):652-63
2J:74152 Yamaza H, Matsuo K, Kiyoshima T, Shigemura N, Kobayashi I, Wada H, Akamime A, Sakai H, Detection of differentially expressed genes in the early developmental stage of the mouse mandible. Int J Dev Biol. 2001 Jun;45(4):675-80
1J:78364 Yin Z, Haynie J, Yang X, Han B, Kiatchoosakun S, Restivo J, Yuan S, Prabhakar NR, Herrup K, Conlon RA, Hoit BD, Watanabe M, Yang YC, The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10488-93
1*J:160941 Zhang N, Fu Z, Linke S, Chicher J, Gorman JJ, Visk D, Haddad GG, Poellinger L, Peet DJ, Powell F, Johnson RS, The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism. Cell Metab. 2010 May 5;11(5):364-78

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory