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Gene Expression Literature Summary
Symbol
Name
ID
Prf1
perforin 1 (pore forming protein)
MGI:97551

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7.5 E8.5 E10.5 E12.5 E13.5 E18.5 E19 P
Immunohistochemistry (section) 1 2 1 1 1 5
In situ reporter (knock in) 1
RT-PCR 1 1 1 3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Prf1  perforin 1 (pore forming protein)   (Synonyms: perforin, Pfn, Pfp, Prf-1)
Results  Reference
2J:93811 Ain R, Trinh ML, Soares MJ, Interleukin-11 signaling is required for the differentiation of natural killer cells at the maternal-fetal interface. Dev Dyn. 2004 Dec;231(4):700-8
2J:278550 Boing M, Brand-Saberi B, Napirei M, Murine transcription factor Math6 is a regulator of placenta development. Sci Rep. 2018 Oct 9;8(1):14997
1J:317072 Dhakal P, Fitzgerald HC, Kelleher AM, Liu H, Spencer TE, Uterine glands impact embryo survival and stromal cell decidualization in mice. FASEB J. 2021 Oct;35(10):e21938
1J:176596 Hu D, Cross JC, Ablation of Tpbpa-positive trophoblast precursors leads to defects in maternal spiral artery remodeling in the mouse placenta. Dev Biol. 2011 Oct 1;358(1):231-9
2J:263890 Kaur G, Helmer RA, Smith LA, Martinez-Zaguilan R, Dufour JM, Chilton BS, Alternative splicing of helicase-like transcription factor (Hltf): Intron retention-dependent activation of immune tolerance at the feto-maternal interface. PLoS One. 2018;13(7):e0200211
1*J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
2J:290696 Lopez-Tello J, Perez-Garcia V, Khaira J, Kusinski LC, Cooper WN, Andreani A, Grant I, Fernandez de Liger E, Lam BY, Hemberger M, Sandovici I, Constancia M, Sferruzzi-Perri AN, Fetal and trophoblast PI3K p110alpha have distinct roles in regulating resource supply to the growing fetus in mice. Elife. 2019 Jun 26;8:e45282
2J:201437 Nagashima T, Li Q, Clementi C, Lydon JP, DeMayo FJ, Matzuk MM, BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest. 2013 Jun 3;123(6):2539-50
3J:215001 Sarkar AA, Nuwayhid SJ, Maynard T, Ghandchi F, Hill JT, Lamantia AS, Zohn IE, Hectd1 is required for development of the junctional zone of the placenta. Dev Biol. 2014 Aug 15;392(2):368-80
2J:288761 Zhang Q, Hao J, Li G, Deletion of Prl7d1 causes placental defects at mid-pregnancy in mice. Mol Reprod Dev. 2019 Jun;86(6):696-713

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory