Gene Expression Literature Summary

• Symbol: Nppc
• Name: natriuretic peptide type C
• ID: MGI:97369

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E5.5	E8.5	E9	E9.5	E10	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17	E17.5	E18.5	E19.5	P
Immunohistochemistry (section)																	1
In situ RNA (section)	1			1		4	1	5	2	3	2	1		2	1	1	3
In situ reporter (knock in)		1	1	3	1	3	3	2	1	1				1
RT-PCR							1	1									1
cDNA clones													1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nppc  natriuretic peptide type C   (Synonyms: CNP, lbab, natriuretic peptide precursor C)
Results	Reference
2	J:335233 Astrof S, Arriagada C, Saijoh Y, Francou A, Kelly RG, Moon A, Aberrant differentiation of second heart field mesoderm prefigures cellular defects in the outflow tract in response to loss of FGF8. Dev Biol. 2023 Apr 14;499:10-21
13	J:31876 Cameron VA, Aitken GD, Ellmers LJ, Kennedy MA, Espiner EA, The sites of gene expression of atrial, brain, and C-type natriuretic peptides in mouse fetal development: temporal changes in embryos and placenta. Endocrinology. 1996 Mar;137(3):817-24
3*	J:91438 DiCicco-Bloom E, Lelievre V, Zhou X, Rodriguez W, Tam J, Waschek JA, Embryonic expression and multifunctional actions of the natriuretic peptides and receptors in the developing nervous system. Dev Biol. 2004 Jul 1;271(1):161-75
1	J:308983 Farmer DT, Mlcochova H, Zhou Y, Koelling N, Wang G, Ashley N, Bugacov H, Chen HJ, Parvez R, Tseng KC, Merrill AE, Maxson RE Jr, Wilkie AOM, Crump JG, Twigg SRF, The developing mouse coronal suture at single-cell resolution. Nat Commun. 2021 Aug 10;12(1):4797
3	J:341969 Jacob T, Annusver K, Czarnewski P, Dalessandri T, Kalk C, Levra Levron C, Campama Sanz N, Kastriti ME, Mikkola ML, Rendl M, Lichtenberger BM, Donati G, Bjorklund AK, Kasper M, Molecular and spatial landmarks of early mouse skin development. Dev Cell. 2023 Oct 23;58(20):2140-2162.e5
1	J:127228 Lee JS, Yu Q, Shin JT, Sebzda E, Bertozzi C, Chen M, Mericko P, Stadtfeld M, Zhou D, Cheng L, Graf T, MacRae CA, Lepore JJ, Lo CW, Kahn ML, Klf2 is an essential regulator of vascular hemodynamic forces in vivo. Dev Cell. 2006 Dec;11(6):845-57
1	J:258361 McCulley DJ, Wienhold MD, Hines EA, Hacker TA, Rogers A, Pewowaruk RJ, Zewdu R, Chesler NC, Selleri L, Sun X, PBX transcription factors drive pulmonary vascular adaptation to birth. J Clin Invest. 2018 Feb 1;128(2):655-667
12	J:153212 Schmidt H, Stonkute A, Juttner R, Koesling D, Friebe A, Rathjen FG, C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16847-52
2	J:82999 Surendran K, Simon TC, CNP gene expression is activated by Wnt signaling and correlates with Wnt4 expression during renal injury. Am J Physiol Renal Physiol. 2003 Apr;284(4):F653-62
1	J:246477 Talchai SC, Accili D, Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult beta-Cell Mass and Function. Diabetes. 2015 Aug;64(8):2868-79
4	J:310594 Ter-Avetisyan G, Dumoulin A, Herrel A, Schmidt H, Strump J, Afzal S, Rathjen FG, Loss of Axon Bifurcation in Mesencephalic Trigeminal Neurons Impairs the Maximal Biting Force in Npr2-Deficient Mice. Front Cell Neurosci. 2018;12:153
4	J:205571 Ter-Avetisyan G, Rathjen FG, Schmidt H, Bifurcation of Axons from Cranial Sensory Neurons Is Disabled in the Absence of Npr2-Induced cGMP Signaling. J Neurosci. 2014 Jan 15;34(3):737-47
2*	J:153667 Zhao Z, Ma L, Regulation of axonal development by natriuretic peptide hormones. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):18016-21