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Gene Expression Literature Summary
Symbol
Name
ID
Nos2
nitric oxide synthase 2, inducible
MGI:97361

34 matching records from 34 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2 E2.5 E3 E3.5 E4 E4.5 E7 E7.5 E8 E8.5 E9 E9.5 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19 E19.5 E20 E A
In situ protein (section) 1 2 1 3 1 3 2 1 2 2 2 2 1 1 3 1 1 5
In situ RNA (section) 1 1 1 1 1 1
In situ protein (whole mount) 1 1 1 1 1 1 1 1 1
In situ RNA (whole mount) 1 1 1 1 1 1 1 1
Northern blot 1 1 1 1 1
Western blot 2 1 2 1 1 1 1 1 1 1 4
RT-PCR 1 1 1 1 1 2 2 1 1 2 2 2 2 1 1 4
RNase protection 1 1 1 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nos2  nitric oxide synthase 2, inducible   (Synonyms: iNOS, Nos-2, Nos2a, NOS-II)
Results  Reference
6J:42234 Arnhold S, Andressen C, Bloch W, Mai JK, Addicks K, NO synthase-II is transiently expressed in embryonic mouse olfactory receptor neurons. Neurosci Lett. 1997 Jul 4;229(3):165-8
5J:96845 Arnhold S, When M, Labbe D, Andressen C, Addicks K, Transient expression of NOS-II during development of the murine enteric nervous system. J Mol Histol. 2004 Nov;35(8-9):741-8
17J:53873 Baylis SA, Strijbos PJ, Sandra A, Russell RJ, Rijhsinghani A, Charles IG, Weiner CP, Temporal expression of inducible nitric oxide synthase in mouse and human placenta. Mol Hum Reprod. 1999 Mar;5(3):277-86
10J:63329 Bloch W, Fleischmann BK, Lorke DE, Andressen C, Hops B, Hescheler J, Addicks K, Nitric oxide synthase expression and role during cardiomyogenesis. Cardiovasc Res. 1999 Aug 15;43(3):675-84
5*J:83933 Cheng A, Wang S, Cai J, Rao MS, Mattson MP, Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain. Dev Biol. 2003 Jun 15;258(2):319-33
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
4J:59951 Gagioti S, Scavone C, Bevilacqua E, Participation of the mouse implanting trophoblast in nitric oxide production during pregnancy. Biol Reprod. 2000 Feb;62(2):260-8
2J:70266 Graef IA, Chen F, Chen L, Kuo A, Crabtree GR, Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell. 2001 Jun 29;105(7):863-75
2*J:142881 Gribar SC, Sodhi CP, Richardson WM, Anand RJ, Gittes GK, Branca MF, Jakub A, Shi XH, Shah S, Ozolek JA, Hackam DJ, Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis. J Immunol. 2009 Jan 1;182(1):636-46
1J:28931 Haddad EK, Duclos AJ, Baines MG, Early embryo loss is associated with local production of nitric oxide by decidual mononuclear cells. J Exp Med. 1995 Oct 1;182(4):1143-51
1*J:40876 Haddad EK, Duclos AJ, Lapp WS, Baines MG, Early embryo loss is associated with the prior expression of macrophage activation markers in the decidua. J Immunol. 1997 May 15;158(10):4886-92
1J:83701 Hemberger M, Nozaki T, Masutani M, Cross JC, Differential expression of angiogenic and vasodilatory factors by invasive trophoblast giant cells depending on depth of invasion. Dev Dyn. 2003 Jun;227(2):185-91
1J:170943 Holscher M, Silter M, Krull S, von Ahlen M, Hesse A, Schwartz P, Wielockx B, Breier G, Katschinski DM, Zieseniss A, Cardiomyocyte-specific Prolyl-4-hydroxylase Domain 2 Knock Out Protects from Acute Myocardial Ischemic Injury. J Biol Chem. 2011 Apr 1;286(13):11185-94
1*J:43062 Hunt JS, Miller L, Vassmer D, Croy BA, Expression of the inducible nitric oxide synthase gene in mouse uterine leukocytes and potential relationships with uterine function during pregnancy. Biol Reprod. 1997 Oct;57(4):827-36
2J:53273 Ji GJ, Fleischmann BK, Bloch W, Feelisch M, Andressen C, Addicks K, Hescheler J, Regulation of the L-type Ca2+ channel during cardiomyogenesis: switch from NO to adenylyl cyclase-mediated inhibition. FASEB J. 1999 Feb;13(2):313-24
1J:152416 Kitamura K, Itou Y, Yanazawa M, Ohsawa M, Suzuki-Migishima R, Umeki Y, Hohjoh H, Yanagawa Y, Shinba T, Itoh M, Nakamura K, Goto Y, Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice. Hum Mol Genet. 2009 Oct 1;18(19):3708-24
1J:79871 Kitamura K, Yanazawa M, Sugiyama N, Miura H, Iizuka-Kogo A, Kusaka M, Omichi K, Suzuki R, Kato-Fukui Y, Kamiirisa K, Matsuo M, Kamijo S, Kasahara M, Yoshioka H, Ogata T, Fukuda T, Kondo I, Kato M, Dobyns WB, Yokoyama M, Morohashi K, Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans. Nat Genet. 2002 Nov;32(3):359-69
3J:170178 Kobayashi K, Umezawa K, Yasui M, Apoptosis in mouse amniotic epithelium is induced by activated macrophages through the TNF receptor type 1/TNF pathway. Biol Reprod. 2011 Feb;84(2):248-54
1J:137621 Lin IC, Smartt JM Jr, Nah HD, Ischiropoulos H, Kirschner RE, Nitric oxide stimulates proliferation and differentiation of fetal calvarial osteoblasts and dural cells. Plast Reconstr Surg. 2008 May;121(5):1554-66; discussion 1567-9
1J:204675 Mandal S, Stanco A, Buys ES, Enikolopov G, Rubenstein JL, Soluble guanylate cyclase generation of cGMP regulates migration of MGE neurons. J Neurosci. 2013 Oct 23;33(43):16897-914
1*J:74121 Meeson AP, Radford N, Shelton JM, Mammen PP, DiMaio JM, Hutcheson K, Kong Y, Elterman J, Williams RS, Garry DJ, Adaptive mechanisms that preserve cardiac function in mice without myoglobin. Circ Res. 2001 Apr 13;88(7):713-20
1J:101254 Miller AA, Hislop AA, Vallance PJ, Haworth SG, Deletion of the eNOS gene has a greater impact on the pulmonary circulation of male than female mice. Am J Physiol Lung Cell Mol Physiol. 2005 Aug;289(2):L299-306
6J:109243 Nath AK, Enciso J, Kuniyasu M, Hao XY, Madri JA, Pinter E, Nitric oxide modulates murine yolk sac vasculogenesis and rescues glucose induced vasculopathy. Development. 2004 May;131(10):2485-96
8J:74206 Nishikimi A, Matsukawa T, Hoshino K, Ikeda S, Kira Y, Sato EF, Inoue M, Yamada M, Localization of nitric oxide synthase activity in unfertilized oocytes and fertilized embryos during preimplantation development in mice. Reproduction. 2001 Dec;122(6):957-63
1J:50463 Pitman JL, Lin TP, Kleeman JE, Erickson GF, MacLeod CL, Normal reproductive and macrophage function in Pem homeobox gene-deficient mice. Dev Biol. 1998 Oct 15;202(2):196-214
4*J:95790 Richard C, Gao J, LaFleur B, Christman BW, Anderson J, Brown N, Reese J, Patency of the preterm fetal ductus arteriosus is regulated by endothelial nitric oxide synthase and is independent of vasa vasorum in the mouse. Am J Physiol Regul Integr Comp Physiol. 2004 Sep;287(3):R652-60
1J:33809 Sanchez MP, Silos-Santiago I, Frisen J, He B, Lira SA, Barbacid M, Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature. 1996 Jul 4;382(6586):70-3
4J:64066 Saxena D, Purohit SB, Kumer GP, Laloraya M, Increased appearance of inducible nitric oxide synthase in the uterus and embryo at implantation. Nitric Oxide. 2000 Aug;4(4):384-91
1*J:135081 Schmidt H, Stonkute A, Juttner R, Schaffer S, Buttgereit J, Feil R, Hofmann F, Rathjen FG, The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord. J Cell Biol. 2007 Oct 22;179(2):331-40
2J:148113 Sugimura Y, Murase T, Oyama K, Uchida A, Sato N, Hayasaka S, Kano Y, Takagishi Y, Hayashi Y, Oiso Y, Murata Y, Prevention of neural tube defects by loss of function of inducible nitric oxide synthase in fetuses of a mouse model of streptozotocin-induced diabetes. Diabetologia. 2009 May;52(5):962-71
5*J:40205 Tai XG, Toyo-oka K, Yamamoto N, Yashiro Y, Mu J, Hamaoka T, Fujiwara H, Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR-stimulated double-positive thymocytes. J Immunol. 1997 May 15;158(10):4696-703
1J:63408 Yip JW, Yip YP, Nakajima K, Capriotti C, Reelin controls position of autonomic neurons in the spinal cord. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8612-6
6J:57952 Young HM, Ciampoli D, Hsuan J, Canty AJ, Expression of Ret-, p75(NTR)-, Phox2a-, Phox2b-, and tyrosine hydroxylase-immunoreactivity by undifferentiated neural crest-derived cells and different classes of enteric neurons in the embryonic mouse gut. Dev Dyn. 1999 Oct;216(2):137-52
1J:99496 Young HM, Turner KN, Bergner AJ, The location and phenotype of proliferating neural-crest-derived cells in the developing mouse gut. Cell Tissue Res. 2005 Apr;320(1):1-9

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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory