About   Help   FAQ
Gene Expression Literature Summary
Symbol
Name
ID
Nefm
neurofilament, medium polypeptide
MGI:97314

716 matching records from 716 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19 E20 E P
Immunohistochemistry (section) 16 8 58 9 77 13 65 9 55 11 51 9 37 3 35 7 32 6 62 1 1 19 142
In situ RNA (section) 1 3 1 3 4 1 3 1 2 5
Immunohistochemistry (whole mount) 2 26 19 141 18 80 10 53 4 33 1 22 1 17 11 6 24 8 24
In situ RNA (whole mount) 1 2 1 1 1
Northern blot 1 1 1 1
Western blot 1 2 1 9
RT-PCR 1 1 3 1 2 1 2 1 1 1 5

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nefm  neurofilament, medium polypeptide   (Synonyms: Nef3, neurofilament-M, NF160, NF165, Nfm, NF-M)
Results  Reference
1J:67399 Abu-Abed S, Dolle P, Metzger D, Beckett B, Chambon P, Petkovich M, The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. Genes Dev. 2001 Jan 15;15(2):226-40
1J:78687 Abu-Issa R, Smyth G, Smoak I, Yamamura K, Meyers EN, Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse. Development. 2002 Oct;129(19):4613-25
5J:172398 Ackermann J, Ashton G, Lyons S, James D, Hornung JP, Jones N, Breitwieser W, Loss of ATF2 Function Leads to Cranial Motoneuron Degeneration during Embryonic Mouse Development. PLoS One. 2011;6(4):e19090
7J:178973 Adameyko I, Lallemend F, Furlan A, Zinin N, Aranda S, Kitambi SS, Blanchart A, Favaro R, Nicolis S, Lubke M, Muller T, Birchmeier C, Suter U, Zaitoun I, Takahashi Y, Ernfors P, Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest. Development. 2012 Jan;139(2):397-410
1J:225514 Ahmed M, Ura K, Streit A, Auditory hair cell defects as potential cause for sensorineural deafness in Wolf-Hirschhorn syndrome. Dis Model Mech. 2015 Sep 1;8(9):1027-35
1J:248848 Ahmed MU, Maurya AK, Cheng L, Jorge EC, Schubert FR, Maire P, Basson MA, Ingham PW, Dietrich S, Engrailed controls epaxial-hypaxial muscle innervation and the establishment of vertebrate three-dimensional mobility. Dev Biol. 2017 Oct 1;430(1):90-104
1J:97282 Akamatsu W, Fujihara H, Mitsuhashi T, Yano M, Shibata S, Hayakawa Y, Okano HJ, Sakakibara S, Takano H, Takano T, Takahashi T, Noda T, Okano H, The RNA-binding protein HuD regulates neuronal cell identity and maturation. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4625-30
1J:69637 Alavizadeh A, Kiernan AE, Nolan P, Lo C, Steel KP, Bucan M, The wheels mutation in the mouse causes vascular, hindbrain, and inner ear defects. Dev Biol. 2001 Jun 1;234(1):244-60
1J:223051 Albert M, Schmitz SU, Kooistra SM, Malatesta M, Morales Torres C, Rekling JC, Johansen JV, Abarrategui I, Helin K, The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3. PLoS Genet. 2013 Apr;9(4):e1003461
1J:60093 Alvarez-Bolado G, Zhou X, Voss AK, Thomas T, Gruss P, Winged helix transcription factor Foxb1 is essential for access of mammillothalamic axons to the thalamus. Development. 2000 Mar;127(5):1029-38
1J:229226 Amaniti EM, Fu C, Lewis S, Saisana M, Magnani D, Mason JO, Theil T, Expansion of the piriform cortex contributes to corticothalamic pathfinding defects in Gli3 conditional mutants. Cereb Cortex. 2015 Feb;25(2):460-71
1J:161300 An MC, Lin W, Yang J, Dominguez B, Padgett D, Sugiura Y, Aryal P, Gould TW, Oppenheim RW, Hester ME, Kaspar BK, Ko CP, Lee KF, Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10702-7
1J:105292 Anderson RB, Stewart AL, Young HM, Phenotypes of neural-crest-derived cells in vagal and sacral pathways. Cell Tissue Res. 2006 Jan;323(1):11-25
1*J:111609 Anderson RM, Stottmann RW, Choi M, Klingensmith J, Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival. Dev Dyn. 2006 Aug 7;235(9):2507-2520
2J:119656 Andrieu D, Meziane H, Marly F, Angelats C, Fernandez PA, Muscatelli F, Sensory defects in Necdin deficient mice result from a loss of sensory neurons correlated within an increase of developmental programmed cell death. BMC Dev Biol. 2006;6:56
1*J:86964 Andrieu D, Watrin F, Niinobe M, Yoshikawa K, Muscatelli F, Fernandez PA, Expression of the Prader-Willi gene Necdin during mouse nervous system development correlates with neuronal differentiation and p75NTR expression. Gene Expr Patterns. 2003 Dec;3(6):761-5
2J:114098 Armentano M, Filosa A, Andolfi G, Studer M, COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth. Development. 2006 Nov;133(21):4151-62
4J:192475 Asahina H, Masuba A, Hirano S, Yuri K, Distribution of protocadherin 9 protein in the developing mouse nervous system. Neuroscience. 2012 Dec 6;225:88-104
1J:65765 Ashery-Padan R, Marquardt T, Zhou X, Gruss P, Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev. 2000 Nov 1;14(21):2701-11
1J:71498 Ayton P, Sneddon SF, Palmer DB, Rosewell IR, Owen MJ, Young B, Presley R, Subramanian V, Truncation of the MLL gene in exon 5 by gene targeting leads to early preimplantation lethality of homozygous embryos. Genesis. 2001 Aug;30(4):201-12
2J:107695 Bagri A, Marin O, Plump AS, Mak J, Pleasure SJ, Rubenstein JL, Tessier-Lavigne M, Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron. 2002 Jan 17;33(2):233-48
1J:188551 Balamotis MA, Pennella MA, Stevens JL, Wasylyk B, Belmont AS, Berk AJ, Complexity in transcription control at the activation domain-mediator interface. Sci Signal. 2009;2(69):ra20
2*J:29060 Bally-Cuif L, Cholley B, Wassef M, Involvement of Wnt-1 in the formation of the mes/metencephalic boundary. Mech Dev. 1995 Sep;53(1):23-34
1J:145949 Baloh RH, Strickland A, Ryu E, Le N, Fahrner T, Yang M, Nagarajan R, Milbrandt J, Congenital hypomyelinating neuropathy with lethal conduction failure in mice carrying the Egr2 I268N mutation. J Neurosci. 2009 Feb 25;29(8):2312-21
1J:76593 Bamforth SD, Braganca J, Eloranta JJ, Murdoch JN, Marques FI, Kranc KR, Farza H, Henderson DJ, Hurst HC, Bhattacharya S, Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat Genet. 2001 Dec;29(4):469-74
2J:110726 Banks GB, Choy PT, Lavidis NA, Noakes PG, Neuromuscular synapses mediate motor axon branching and motoneuron survival during the embryonic period of programmed cell death. Dev Biol. 2003 May 1;257(1):71-84
1J:162066 Barnes AP, Lilley BN, Pan YA, Plummer LJ, Powell AW, Raines AN, Sanes JR, Polleux F, LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell. 2007 May 4;129(3):549-63
1*J:132131 Barton KM, Levine EM, Expression patterns and cell cycle profiles of PCNA, MCM6, cyclin D1, cyclin A2, cyclin B1, and phosphorylated histone H3 in the developing mouse retina. Dev Dyn. 2008 Mar;237(3):672-82
1J:181601 Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA, Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29
1J:152494 Behesti H, Papaioannou VE, Sowden JC, Loss of Tbx2 delays optic vesicle invagination leading to small optic cups. Dev Biol. 2009 Sep 15;333(2):360-72
1J:127639 Ben-Zvi A, Ben-Gigi L, Klein H, Behar O, Modulation of Semaphorin3A activity by p75 neurotrophin receptor influences peripheral axon patterning. J Neurosci. 2007 Nov 21;27(47):13000-11
4J:65134 Bentley CA, Lee KF, p75 is important for axon growth and schwann cell migration during development. J Neurosci. 2000 Oct 15;20(20):7706-15
1J:236786 Bergeron KF, Nguyen CM, Cardinal T, Charrier B, Silversides DW, Pilon N, Upregulation of the Nr2f1-A830082K12Rik gene pair in murine neural crest cells results in a complex phenotype reminiscent of Waardenburg syndrome type 4. Dis Model Mech. 2016 Nov 1;9(11):1283-1293
4J:162756 Bergwerff M, DeRuiter MC, Hall S, Poelmann RE, Gittenberger-de Groot AC, Unique vascular morphology of the fourth aortic arches: possible implications for pathogenesis of type-B aortic arch interruption and anomalous right subclavian artery. Cardiovasc Res. 1999 Oct;44(1):185-96
1J:42573 Berk M, Desai SY, Heyman HC, Colmenares C, Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development. Genes Dev. 1997 Aug 15;11(16):2029-39
1J:69624 Bermingham NA, Hassan BA, Wang VY, Fernandez M, Banfi S, Bellen HJ, Fritzsch B, Zoghbi HY, Proprioceptor pathway development is dependent on math1. Neuron. 2001 May;30(2):411-22
1J:188155 Bharti K, Gasper M, Ou J, Brucato M, Clore-Gronenborn K, Pickel J, Arnheiter H, A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet. 2012 Jul;8(7):e1002757
1J:174731 Bielle F, Marcos-Mondejar P, Keita M, Mailhes C, Verney C, Nguyen Ba-Charvet K, Tessier-Lavigne M, Lopez-Bendito G, Garel S, Slit2 activity in the migration of guidepost neurons shapes thalamic projections during development and evolution. Neuron. 2011 Mar 24;69(6):1085-98
2J:227232 Bin JM, Han D, Lai Wing Sun K, Croteau LP, Dumontier E, Cloutier JF, Kania A, Kennedy TE, Complete Loss of Netrin-1 Results in Embryonic Lethality and Severe Axon Guidance Defects without Increased Neural Cell Death. Cell Rep. 2015 Aug 18;12(7):1099-106
1J:85746 Blanchi B, Kelly LM, Viemari JC, Lafon I, Burnet H, Bevengut M, Tillmanns S, Daniel L, Graf T, Hilaire G, Sieweke MH, MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth. Nat Neurosci. 2003 Oct;6(10):1091-100
1J:86183 Boettger T, Rust MB, Maier H, Seidenbecher T, Schweizer M, Keating DJ, Faulhaber J, Ehmke H, Pfeffer C, Scheel O, Lemcke B, Horst J, Leuwer R, Pape HC, Volkl H, Hubner CA, Jentsch TJ, Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold. EMBO J. 2003 Oct 15;22(20):5422-34
2*J:32118 Boisseau S, Nedelec J, Poirier V, Rougon G, Simonneau M, Analysis of high PSA N-CAM expression during mammalian spinal cord and peripheral nervous system development. Development. 1991 May;112(1):69-82
1*J:75290 Bolino A, Marigo V, Ferrera F, Loader J, Romio L, Leoni A, Di Duca M, Cinti R, Cecchi C, Feltri ML, Wrabetz L, Ravazzolo R, Monaco AP, Molecular characterization and expression analysis of Mtmr2, mouse homologue of MTMR2, the Myotubularin-related 2 gene, mutated in CMT4B. Gene. 2002 Jan 23;283(1-2):17-26
4J:104207 Bonadio J, Jepsen KJ, Mansoura MK, Jaenisch R, Kuhn JL, Goldstein SA, A murine skeletal adaptation that significantly increases cortical bone mechanical properties. Implications for human skeletal fragility. J Clin Invest. 1993 Oct;92(4):1697-705
1J:180801 Bonanomi D, Chivatakarn O, Bai G, Abdesselem H, Lettieri K, Marquardt T, Pierchala BA, Pfaff SL, Ret Is a Multifunctional Coreceptor that Integrates Diffusible- and Contact-Axon Guidance Signals. Cell. 2012 Feb 3;148(3):568-82
1*J:34198 Boulet AM, Capecchi MR, Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations. Dev Biol. 1996 Jul 10;177(1):232-49
1J:157721 Bourane S, Garces A, Venteo S, Pattyn A, Hubert T, Fichard A, Puech S, Boukhaddaoui H, Baudet C, Takahashi S, Valmier J, Carroll P, Low-threshold mechanoreceptor subtypes selectively express MafA and are specified by Ret signaling. Neuron. 2009 Dec 24;64(6):857-70
1J:260635 Bowerman M, Salsac C, Bernard V, Soulard C, Dionne A, Coque E, Benlefki S, Hince P, Dion PA, Butler-Browne G, Camu W, Bouchard JP, Delpire E, Rouleau GA, Raoul C, Scamps F, KCC3 loss-of-function contributes to Andermann syndrome by inducing activity-dependent neuromuscular junction defects. Neurobiol Dis. 2017 Oct;106:35-48
4J:81738 Brandon EP, Lin W, D'Amour KA, Pizzo DP, Dominguez B, Sugiura Y, Thode S, Ko CP, Thal LJ, Gage FH, Lee KF, Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice. J Neurosci. 2003 Jan 15;23(2):539-49
1J:88826 Brewer S, Feng W, Huang J, Sullivan S, Williams T, Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects. Dev Biol. 2004 Mar 1;267(1):135-52
1J:278101 Brightman DS, Grant RL, Ruzycki PA, Suzuki R, Hennig AK, Chen S, MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity. Sci Rep. 2018 Aug 9;8(1):11902
1J:48515 Britsch S, Li L, Kirchhoff S, Theuring F, Brinkmann V, Birchmeier C, Riethmacher D, The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system. Genes Dev. 1998 Jun 15;12(12):1825-36
2J:68904 Brouns MR, Matheson SF, Settleman J, p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat Cell Biol. 2001 Apr;3(4):361-7
1J:180898 Brown AS, Epstein DJ, Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development. Development. 2011 Sep;138(18):3967-76
2J:70746 Brown NL, Patel S, Brzezinski J, Glaser T, Math5 is required for retinal ganglion cell and optic nerve formation. Development. 2001 Jul;128(13):2497-508
1J:140213 Buccafusca R, Venditti CP, Kenyon LC, Johanson RA, Van Bockstaele E, Ren J, Pagliardini S, Minarcik J, Golden JA, Coady MJ, Greer JJ, Berry GT, Characterization of the null murine sodium/myo-inositol cotransporter 1 (Smit1 or Slc5a3) phenotype: myo-inositol rescue is independent of expression of its cognate mitochondrial ribosomal protein subunit 6 (Mrps6) gene and of phosphatidylinositol levelsin neonatal brain. Mol Genet Metab. 2008 Sep-Oct;95(1-2):81-95
2J:49830 Buchman VL, Adu J, Pinon LG, Ninkina NN, Davies AM, Persyn, a member of the synuclein family, influences neurofilament network integrity. Nat Neurosci. 1998 Jun;1(2):101-3
1J:149223 Buchmann-Moller S, Miescher I, John N, Krishnan J, Deng CX, Sommer L, Multiple lineage-specific roles of Smad4 during neural crest development. Dev Biol. 2009 Jun 15;330(2):329-38
1J:32083 Burmeister M, Novak J, Liang MY, Basu S, Ploder L, Hawes NL, Vidgen D, Hoover F, Goldman D, Kalnins VI, Roderick TH, Taylor BA, Hankin MH, McInnes RR, Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation. Nat Genet. 1996 Apr;12(4):376-84
1J:150043 Bush JO, Soriano P, Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009 Jul 1;23(13):1586-99
1J:90513 Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A, The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev. 2004 May 15;18(10):1209-21
1J:159309 Buttner N, Johnsen SA, Kugler S, Vogel T, Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7042-7
1J:100584 Byrd NA, Meyers EN, Loss of Gbx2 results in neural crest cell patterning and pharyngeal arch artery defects in the mouse embryo. Dev Biol. 2005 Aug 1;284(1):233-45
1J:68750 Cacalano G, Farinas I, Wang LC, Hagler K, Forgie A, Moore M, Armanini M, Phillips H, Ryan AM, Reichardt LF, Hynes M, Davies A, Rosenthal A, GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney. Neuron. 1998 Jul;21(1):53-62
1J:159104 Cai Z, Feng GS, Zhang X, Temporal requirement of the protein TyrosinePhosphatase Shp2 in establishing the neuronal fatein early retinal development. J Neurosci. 2010 Mar 17;30(11):4110-9
3J:214343 Cai Z, Grobe K, Zhang X, Role of heparan sulfate proteoglycans in optic disc and stalk morphogenesis. Dev Dyn. 2014 Oct;243(10):1310-6
1J:174095 Cai Z, Simons DL, Fu XY, Feng GS, Wu SM, Zhang X, Loss of shp2-mediated mitogen-activated protein kinase signaling in muller glial cells results in retinal degeneration. Mol Cell Biol. 2011 Jul;31(14):2973-83
1J:198655 Cai Z, Tao C, Li H, Ladher R, Gotoh N, Feng GS, Wang F, Zhang X, Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma. Development. 2013 Jul;140(13):2711-23
1J:198381 Carbe C, Garg A, Cai Z, Li H, Powers A, Zhang X, An allelic series at the paired box gene 6 (Pax6) locus reveals the functional specificity of Pax genes. J Biol Chem. 2013 Apr 26;288(17):12130-41
1J:213869 Caronia-Brown G, Yoshida M, Gulden F, Assimacopoulos S, Grove EA, The cortical hem regulates the size and patterning of neocortex. Development. 2014 Jul;141(14):2855-65
1J:211808 Carpanini SM, McKie L, Thomson D, Wright AK, Gordon SL, Roche SL, Handley MT, Morrison H, Brownstein D, Wishart TM, Cousin MA, Gillingwater TH, Aligianis IA, Jackson IJ, A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton. Dis Model Mech. 2014 Jun;7(6):711-22
1*J:44765 Carpenter EM, Goddard JM, Davis AP, Nguyen TP, Capecchi MR, Targeted disruption of Hoxd-10 affects mouse hindlimb development. Development. 1997 Nov;124(22):4505-14
1J:199157 Caruso N, Herberth B, Bartoli M, Puppo F, Dumonceaux J, Zimmermann A, Denadai S, Lebosse M, Roche S, Geng L, Magdinier F, Attarian S, Bernard R, Maina F, Levy N, Helmbacher F, Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy. PLoS Genet. 2013 Jun;9(6):e1003550
2*J:60988 Caton A, Hacker A, Naeem A, Livet J, Maina F, Bladt F, Klein R, Birchmeier C, Guthrie S, The branchial arches and HGF are growth-promoting and chemoattractant for cranial motor axons. Development. 2000 Apr;127(8):1751-66
2J:215832 Chai G, Zhou L, Manto M, Helmbacher F, Clotman F, Goffinet AM, Tissir F, Celsr3 is required in motor neurons to steer their axons in the hindlimb. Nat Neurosci. 2014 Sep;17(9):1171-9
2J:176125 Chalazonitis A, Tang AA, Shang Y, Pham TD, Hsieh I, Setlik W, Gershon MD, Huang EJ, Homeodomain Interacting Protein Kinase 2 Regulates Postnatal Development of Enteric Dopaminergic Neurons and Glia via BMP Signaling. J Neurosci. 2011 Sep 28;31(39):13746-57
2*J:94397 Chan R, Hardy WR, Dankort D, Laing MA, Muller WJ, Modulation of Erbb2 signaling during development: a threshold level of Erbb2 signaling is required for development. Development. 2004 Nov;131(22):5551-60
5J:258111 Charoy C, Dinvaut S, Chaix Y, Morle L, Sanyas I, Bozon M, Kindbeiter K, Durand B, Skidmore JM, De Groef L, Seki M, Moons L, Ruhrberg C, Martin JF, Martin DM, Falk J, Castellani V, Genetic specification of left-right asymmetry in the diaphragm muscles and their motor innervation. Elife. 2017 Jun 22;6
2J:188327 Charoy C, Nawabi H, Reynaud F, Derrington E, Bozon M, Wright K, Falk J, Helmbacher F, Kindbeiter K, Castellani V, gdnf Activates Midline Repulsion by Semaphorin3B via NCAM during Commissural Axon Guidance. Neuron. 2012 Sep 20;75(6):1051-66
1J:189961 Chatterjee M, Li K, Chen L, Maisano X, Guo Q, Gan L, Li JY, Gbx2 regulates thalamocortical axon guidance by modifying the LIM and Robo codes. Development. 2012 Dec;139(24):4633-43
1J:138244 Chatzopoulou E, Miguez A, Savvaki M, Levasseur G, Muzerelle A, Muriel MP, Goureau O, Watanabe K, Goutebroze L, Gaspar P, Zalc B, Karagogeos D, Thomas JL, Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the mouse optic nerve. J Neurosci. 2008 Jul 23;28(30):7624-36
1J:132724 Chauvet S, Cohen S, Yoshida Y, Fekrane L, Livet J, Gayet O, Segu L, Buhot MC, Jessell TM, Henderson CE, Mann F, Gating of Sema3E/PlexinD1 signaling by neuropilin-1 switches axonal repulsion to attraction during brain development. Neuron. 2007 Dec 6;56(5):807-22
1J:241784 Chaverra M, George L, Mergy M, Waller H, Kujawa K, Murnion C, Sharples E, Thorne J, Podgajny N, Grindeland A, Ueki Y, Eiger S, Cusick C, Babcock AM, Carlson GA, Lefcort F, The familial dysautonomia disease gene IKBKAP is required in the developing and adult mouse central nervous system. Dis Model Mech. 2017 May 01;10(5):605-618
1J:171672 Cheever TR, Olson EA, Ervasti JM, Axonal regeneration and neuronal function are preserved in motor neurons lacking ss-actin in vivo. PLoS One. 2011;6(3):e17768
1J:80747 Chen B, Hammonds-Odie L, Perron J, Masters BA, Bixby JL, SHP-2 Mediates Target-Regulated Axonal Termination and NGF-Dependent Neurite Growth in Sympathetic Neurons. Dev Biol. 2002 Dec 15;252(2):170-87
2J:172291 Chen F, Liu Y, Sugiura Y, Allen PD, Gregg RG, Lin W, Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors. Nat Neurosci. 2011 May;14(5):570-7
4J:60158 Chen H, Bagri A, Zupicich JA, Zou Y, Stoeckli E, Pleasure SJ, Lowenstein DH, Skarnes WC, Chedotal A, Skarnes WC, Tessier-Lavigne M, Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Neuron. 2000 Jan;25(1):43-56
1J:183920 Chen J, Lai F, Niswander L, The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev. 2012 Apr 15;26(8):803-15
1J:224504 Chen JF, Zhang Y, Wilde J, Hansen KC, Lai F, Niswander L, Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. Nat Commun. 2014;5:3885
1J:154602 Chen Y, Wu H, Wang S, Koito H, Li J, Ye F, Hoang J, Escobar SS, Gow A, Arnett HA, Trapp BD, Karandikar NJ, Hsieh J, Lu QR, The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination. Nat Neurosci. 2009 Nov;12(11):1398-406
2J:72426 Cheng HJ, Bagri A, Yaron A, Stein E, Pleasure SJ, Tessier-Lavigne M, Plexin-a3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections. Neuron. 2001 Oct 25;32(2):249-63
2J:213171 Cheng L, Desai J, Miranda CJ, Duncan JS, Qiu W, Nugent AA, Kolpak AL, Wu CC, Drokhlyansky E, Delisle MM, Chan WM, Wei Y, Propst F, Reck-Peterson SL, Fritzsch B, Engle EC, Human CFEOM1 mutations attenuate KIF21A autoinhibition and cause oculomotor axon stalling. Neuron. 2014 Apr 16;82(2):334-49
1*J:122606 Cheng LE, Zhang J, Reed RR, The transcription factor Zfp423/OAZ is required for cerebellar development and CNS midline patterning. Dev Biol. 2007 Jul 1;307(1):43-52
1*J:83255 Chi CL, Martinez S, Wurst W, Martin GR, The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum. Development. 2003 Jun;130(12):2633-44
3J:51146 Chien CL, Lee TH, Lu KS, Distribution of neuronal intermediate filament proteins in the developing mouse olfactory system. J Neurosci Res. 1998 Nov 1;54(3):353-63
2J:1776 Chisaka O, Musci TS, Capecchi MR, Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6 [see comments]. Nature. 1992 Feb 6;355(6360):516-20
1J:182705 Choe Y, Siegenthaler JA, Pleasure SJ, A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron. 2012 Feb 23;73(4):698-712
2J:207796 Choi HY, Liu Y, Tennert C, Sugiura Y, Karakatsani A, Kroger S, Johnson EB, Hammer RE, Lin W, Herz J, APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice. Elife. 2013;2:e00220
1J:234117 Chojnowski JL, Trau HA, Masuda K, Manley NR, Temporal and spatial requirements for Hoxa3 in mouse embryonic development. Dev Biol. 2016 Jul 1;415(1):33-45
1J:108393 Chung AC, Xu X, Niederreither KA, Cooney AJ, Loss of orphan nuclear receptor GCNF function disrupts forebrain development and the establishment of the isthmic organizer. Dev Biol. 2006 May 1;293(1):13-24
2J:248927 Clements R, Turk R, Campbell KP, Wright KM, Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development. J Neurosci. 2017 Aug 30;37(35):8559-8574
1J:266267 Clements R, Wright KM, Retinal ganglion cell axon sorting at the optic chiasm requires dystroglycan. Dev Biol. 2018 Oct 15;442(2):210-219
2*J:46639 Clouthier DE, Hosoda K, Richardson JA, Williams SC, Yanagisawa H, Kuwaki T, Kumada M, Hammer RE, Yanagisawa M, Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. Development. 1998 Mar;125(5):813-24
1J:171491 Clugston RD, Zhang W, Alvarez S, de Lera AR, Greer JJ, Understanding abnormal retinoid signaling as a causative mechanism in congenital diaphragmatic hernia. Am J Respir Cell Mol Biol. 2010 Mar;42(3):276-85
2*J:25248 Conlon RA, Reaume AG, Rossant J, Notch1 is required for the coordinate segmentation of somites. Development. 1995 May;121(5):1533-45
1*J:137690 Cooley MA, Kern CB, Fresco VM, Wessels A, Thompson RP, McQuinn TC, Twal WO, Mjaatvedt CH, Drake CJ, Argraves WS, Fibulin-1 is required for morphogenesis of neural crest-derived structures. Dev Biol. 2008 Jul 15;319(2):336-45
1J:126634 Coppola E, Pattyn A, Guthrie SC, Goridis C, Studer M, Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation. EMBO J. 2005 Dec 21;24(24):4392-403
2J:157532 Coppola E, Rallu M, Richard J, Dufour S, Riethmacher D, Guillemot F, Goridis C, Brunet JF, Epibranchial ganglia orchestrate the development of the cranial neurogenic crest. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2066-71
4J:72304 Coppola V, Kucera J, Palko ME, Martinez-De Velasco J, Lyons WE, Fritzsch B, Tessarollo L, Dissection of NT3 functions in vivo by gene replacement strategy. Development. 2001 Nov;128(21):4315-27
3J:159829 Coulpier F, Decker L, Funalot B, Vallat JM, Garcia-Bragado F, Charnay P, Topilko P, CNS/PNS boundary transgression by central glia in the absence of Schwann cells or Krox20/Egr2 function. J Neurosci. 2010 Apr 28;30(17):5958-67
1J:240677 Crabtree GW, Sun Z, Kvajo M, Broek JA, Fenelon K, McKellar H, Xiao L, Xu B, Bahn S, O'Donnell JM, Gogos JA, Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness. J Neurosci. 2017 Apr 12;37(15):4158-4180
1J:271200 da Silva RV, Johannssen HC, Wyss MT, Roome RB, Bourojeni FB, Stifani N, Marsh APL, Ryan MM, Lockhart PJ, Leventer RJ, Richards LJ, Rosenblatt B, Srour M, Weber B, Zeilhofer HU, Kania A, DCC Is Required for the Development of Nociceptive Topognosis in Mice and Humans. Cell Rep. 2018 Jan 30;22(5):1105-1114
3*J:22536 Dahlstrand J, Lardelli M, Lendahl U, Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system. Brain Res Dev Brain Res. 1995 Jan 14;84(1):109-29
1J:219045 Dai X, Jiang W, Zhang Q, Xu L, Geng P, Zhuang S, Petrich BG, Jiang C, Peng L, Bhattacharya S, Evans SM, Sun Y, Chen J, Liang X, Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis. BMC Biol. 2013;11:107
2*J:86960 Darling DS, Stearman RP, Qi Y, Qiu MS, Feller JP, Expression of Zfhep/deltaEF1 protein in palate, neural progenitors, and differentiated neurons. Gene Expr Patterns. 2003 Dec;3(6):709-17
1J:160729 Das G, Choi Y, Sicinski P, Levine EM, Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells. Neural Dev. 2009;4:15
1J:54652 Davenne M, Maconochie MK, Neun R, Pattyn A, Chambon P, Krumlauf R, Rijli FM, Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrain. Neuron. 1999 Apr;22(4):677-91
1J:137000 Davies D, Temporal and spatial regulation of alpha6 integrin expression during the development of the cochlear-vestibular ganglion. J Comp Neurol. 2007 Jun 10;502(5):673-82
2*J:75058 Davies D, Holley MC, Differential expression of alpha3 and alpha6 integrins in the developing mouse inner ear. J Comp Neurol. 2002 Apr 1;445(2):122-32
1J:180843 Davis N, Mor E, Ashery-Padan R, Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium. Development. 2011 Jan;138(1):127-38
1*J:89008 Davy A, Aubin J, Soriano P, Ephrin-B1 forward and reverse signaling are required during mouse development. Genes Dev. 2004 Mar 1;18(5):572-83
1J:143845 Davy A, Soriano P, Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development. Dev Biol. 2007 Apr 1;304(1):182-93
1*J:153908 de Castro BM, De Jaeger X, Martins-Silva C, Lima RD, Amaral E, Menezes C, Lima P, Neves CM, Pires RG, Gould TW, Welch I, Kushmerick C, Guatimosim C, Izquierdo I, Cammarota M, Rylett RJ, Gomez MV, Caron MG, Oppenheim RW, Prado MA, Prado VF, The vesicular acetylcholine transporter is required for neuromuscular development and function. Mol Cell Biol. 2009 Oct;29(19):5238-50
1*J:59070 de la Cruz CC, Der-Avakian A, Spyropoulos DD, Tieu DD, Carpenter EM, Targeted disruption of Hoxd9 and Hoxd10 alters locomotor behavior, vertebral identity, and peripheral nervous system development. Dev Biol. 1999 Dec 15;216(2):595-610
1J:95327 de Melo J, Du G, Fonseca M, Gillespie LA, Turk WJ, Rubenstein JL, Eisenstat DD, Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina. Development. 2005 Jan;132(2):311-22
2J:173617 de Melo J, Peng GH, Chen S, Blackshaw S, The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons. Development. 2011 Jun;138(11):2325-36
1J:83565 De Melo J, Qiu X, Du G, Cristante L, Eisenstat DD, Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina. J Comp Neurol. 2003 Jun 23;461(2):187-204
1J:172162 de Melo J, Zhou QP, Zhang Q, Zhang S, Fonseca M, Wigle JT, Eisenstat DD, Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development. Nucleic Acids Res. 2008 Feb;36(3):872-84
1J:143171 De Pietri Tonelli D, Pulvers JN, Haffner C, Murchison EP, Hannon GJ, Huttner WB, miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex. Development. 2008 Dec;135(23):3911-21
1J:197849 Deck M, Lokmane L, Chauvet S, Mailhes C, Keita M, Niquille M, Yoshida M, Yoshida Y, Lebrand C, Mann F, Grove EA, Garel S, Pathfinding of corticothalamic axons relies on a rendezvous with thalamic projections. Neuron. 2013 Feb 6;77(3):472-84
1J:237345 Dee A, Li K, Heng X, Guo Q, Li JY, Regulation of self-renewing neural progenitors by FGF/ERK signaling controls formation of the inferior colliculus. Development. 2016 Oct 15;143(20):3661-3673
1J:121970 Deng S, Hirschberg A, Worzfeld T, Penachioni JY, Korostylev A, Swiercz JM, Vodrazka P, Mauti O, Stoeckli ET, Tamagnone L, Offermanns S, Kuner R, Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo. J Neurosci. 2007 Jun 6;27(23):6333-47
1*J:14064 Denis-Donini S, Chini B, Vitadello M, Developmentally regulated expression of CGRP in the mouse olfactory pathway. Eur J Neurosci. 1993;5(6):648-56
1J:190013 Dennis JF, Kurosaka H, Iulianella A, Pace J, Thomas N, Beckham S, Williams T, Trainor PA, Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects. PLoS Genet. 2012 Oct;8(10):e1002927
1*J:56559 Depew MJ, Liu JK, Long JE, Presley R, Meneses JJ, Pedersen RA, Rubenstein JL, Dlx5 regulates regional development of the branchial arches and sensory capsules. Development. 1999 Sep;126(17):3831-46
3J:106423 Dessaud E, Salaun D, Gayet O, Chabbert M, deLapeyriere O, Identification of lynx2, a novel member of the ly-6/neurotoxin superfamily, expressed in neuronal subpopulations during mouse development. Mol Cell Neurosci. 2006 Feb;31(2):232-42
1J:104550 Dettlaff-Swiercz DA, Wettschureck N, Moers A, Huber K, Offermanns S, Characteristic defects in neural crest cell-specific Galphaq/Galpha11- and Galpha12/Galpha13-deficient mice. Dev Biol. 2005 Jun 1;282(1):174-82
4J:262055 Dhumale P, Menon S, Chiang J, Puschel AW, The loss of the kinases SadA and SadB results in early neuronal apoptosis and a reduced number of progenitors. PLoS One. 2018;13(4):e0196698
1J:271140 Diacou R, Zhao Y, Zheng D, Cvekl A, Liu W, Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation. Cell Rep. 2018 Nov 27;25(9):2510-2523.e4
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4J:102358 Dillon AK, Fujita SC, Matise MP, Jarjour AA, Kennedy TE, Kollmus H, Arnold HH, Weiner JA, Sanes JR, Kaprielian Z, Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord. J Neurosci. 2005 Nov 2;25(44):10119-30
1J:109352 Dillon TE, Saldanha J, Giger R, Verhaagen J, Rochlin MW, Sema3A regulates the timing of target contact by cranial sensory axons. J Comp Neurol. 2004 Feb 23;470(1):13-24
2J:98501 Ding YQ, Kim JY, Xu YS, Rao Y, Chen ZF, Ventral migration of early-born neurons requires Dcc and is essential for the projections of primary afferents in the spinal cord. Development. 2005 May;132(9):2047-56
3J:111207 Dionne MS, Brunet LJ, Eimon PM, Harland RM, Noggin is required for correct guidance of dorsal root ganglion axons. Dev Biol. 2002 Nov 15;251(2):283-93
1J:89223 Dixon J, Dixon MJ, Genetic background has a major effect on the penetrance and severity of craniofacial defects in mice heterozygous for the gene encoding the nucleolar protein Treacle. Dev Dyn. 2004 Apr;229(4):907-14
1J:249067 Dominici C, Moreno-Bravo JA, Puiggros SR, Rappeneau Q, Rama N, Vieugue P, Bernet A, Mehlen P, Chedotal A, Floor-plate-derived netrin-1 is dispensable for commissural axon guidance. Nature. 2017 May 18;545(7654):350-354
3J:252860 Dorninger F, Herbst R, Kravic B, Camurdanoglu BZ, Macinkovic I, Zeitler G, Forss-Petter S, Strack S, Khan MM, Waterham HR, Rudolf R, Hashemolhosseini S, Berger J, Reduced muscle strength in ether lipid-deficient mice is accompanied by altered development and function of the neuromuscular junction. J Neurochem. 2017 Dec;143(5):569-583
4J:238334 Dragich JM, Kuwajima T, Hirose-Ikeda M, Yoon MS, Eenjes E, Bosco JR, Fox LM, Lystad AH, Oo TF, Yarygina O, Mita T, Waguri S, Ichimura Y, Komatsu M, Simonsen A, Burke RE, Mason CA, Yamamoto A, Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain. Elife. 2016 Sep 20;5
1J:139256 Driver EC, Pryor SP, Hill P, Turner J, Ruther U, Biesecker LG, Griffith AJ, Kelley MW, Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. J Neurosci. 2008 Jul 16;28(29):7350-8
1J:184451 Dudanova I, Kao TJ, Herrmann JE, Zheng B, Kania A, Klein R, Genetic evidence for a contribution of EphA:ephrinA reverse signaling to motor axon guidance. J Neurosci. 2012 Apr 11;32(15):5209-15
2*J:75954 Dunwoodie SL, Clements M, Sparrow DB, Sa X, Conlon RA, Beddington RS, Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm. Development. 2002 Apr;129(7):1795-806
1*J:38388 Dupe V, Davenne M, Brocard J, Dolle P, Mark M, Dierich A, Chambon P, Rijli FM, In vivo functional analysis of the Hoxa-1 3' retinoic acid response element (3'RARE). Development. 1997 Jan;124(2):399-410
1*J:41551 Dupe V, Ghyselinck NB, Wendling O, Chambon P, Mark M, Key roles of retinoic acid receptors alpha and beta in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse. Development. 1999 Nov;126(22):5051-9
1J:30830 Durbec PL, Larsson-Blomberg LB, Schuchardt A, Costantini F, Pachnis V, Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts. Development. 1996 Jan;122(1):349-58
1J:168258 Dwyer ND, Manning DK, Moran JL, Mudbhary R, Fleming MS, Favero CB, Vock VM, O'Leary DD, Walsh CA, Beier DR, A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype. Neural Dev. 2011;6:3
2J:211702 Dyachuk V, Furlan A, Shahidi MK, Giovenco M, Kaukua N, Konstantinidou C, Pachnis V, Memic F, Marklund U, Muller T, Birchmeier C, Fried K, Ernfors P, Adameyko I, Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors. Science. 2014 Jul 4;345(6192):82-7
1J:189829 Edqvist PH, Niklasson M, Vidal-Sanz M, Hallbook F, Forsberg-Nilsson K, Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation. PLoS One. 2012;7(8):e42488
1J:201994 Ehrman LA, Mu X, Waclaw RR, Yoshida Y, Vorhees CV, Klein WH, Campbell K, The LIM homeobox gene Isl1 is required for the correct development of the striatonigral pathway in the mouse. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):E4026-35
1J:209617 Ehrman LA, Nardini D, Ehrman S, Rizvi TA, Gulick J, Krenz M, Dasgupta B, Robbins J, Ratner N, Nakafuku M, Waclaw RR, The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon. J Neurosci. 2014 Mar 5;34(10):3767-78
1J:260849 El-Hassan AR, Leung V, Kharfallah F, Guyot MC, Allache R, Gros P, Kibar Z, Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2. Mamm Genome. 2018 Apr;29(3-4):229-244
1J:196080 Elsen GE, Hodge RD, Bedogni F, Daza RA, Nelson BR, Shiba N, Reiner SL, Hevner RF, The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
2J:145295 Elstrott J, Anishchenko A, Greschner M, Sher A, Litke AM, Chichilnisky EJ, Feller MB, Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves. Neuron. 2008 May 22;58(4):499-506
2J:206541 Engelhard C, Sarsfield S, Merte J, Wang Q, Li P, Beppu H, Kolodkin AL, Sucov HM, Ginty DD, MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons. Elife. 2013;2:e01160
2J:130616 Enomoto H, Hughes I, Golden J, Baloh RH, Yonemura S, Heuckeroth RO, Johnson EM Jr, Milbrandt J, GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Neuron. 2004 Nov 18;44(4):623-36
2J:187343 Erickson CS, Zaitoun I, Haberman KM, Gosain A, Druckenbrod NR, Epstein ML, Sacral neural crest-derived cells enter the aganglionic colon of Ednrb-/- mice along extrinsic nerve fibers. J Comp Neurol. 2012 Feb 15;520(3):620-32
1J:41620 Ericson J, Rashbass P, Schedl A, Brenner-Morton S, Kawakami A , van Heyningen V , Jessell TM , Briscoe J, Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell. 1997 Jul 11;90(1):169-80
2*J:17123 Ernfors P, Lee KF, Jaenisch R, Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature. 1994 Mar 10;368(6467):147-50
1J:26749 Ernfors P, Van De Water T, Loring J, Jaenisch R, Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron. 1995 Jun;14(6):1153-64
5J:242893 Erskine L, Francois U, Denti L, Joyce A, Tillo M, Bruce F, Vargesson N, Ruhrberg C, VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels. Development. 2017 Jul 01;144(13):2504-2516
5J:253866 Espinosa-Medina I, Jevans B, Boismoreau F, Chettouh Z, Enomoto H, Muller T, Birchmeier C, Burns AJ, Brunet JF, Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):11980-11985
5J:249229 Espinosa-Medina I, Outin E, Picard CA, Chettouh Z, Dymecki S, Consalez GG, Coppola E, Brunet JF, Neurodevelopment. Parasympathetic ganglia derive from Schwann cell precursors. Science. 2014 Jul 4;345(6192):87-90
2J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897
1J:58961 Esterbauer H, Oberkofler H, Krempler F, Patsch W, Human peroxisome proliferator activated receptor gamma coactivator 1 (PPARGC1) gene: cDNA sequence, genomic organization, chromosomal localization, and tissue expression. Genomics. 1999 Nov 15;62(1):98-102
1J:48859 Evrard YA, Lun Y, Aulehla A, Gan L, Johnson RL, lunatic fringe is an essential mediator of somite segmentation and patterning. Nature. 1998 Jul 23;394(6691):377-81
3*J:40091 Fanarraga ML, Charite J, Hage WJ, De Graaff W, Deschamps J, Hoxb-8 gain-of-function transgenic mice exhibit alterations in the peripheral nervous system. J Neurosci Methods. 1997 Jan;71(1):11-8
1J:49434 Farinas I, Wilkinson GA, Backus C, Reichardt LF, Patapoutian A, Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivo. Neuron. 1998 Aug;21(2):325-34
7J:37463 Farinas I, Yoshida CK, Backus C, Reichardt LF, Lack of neurotrophin-3 results in death of spinal sensory neurons and premature differentiation of their precursors. Neuron. 1996 Dec;17(6):1065-78
4J:54791 Faussone-Pellegrini MS, Matini P, DeFelici M, The cytoskeleton of the myenteric neurons during murine embryonic life. Anat Embryol (Berl). 1999 May;199(5):459-69
2J:39765 Fazeli A, Dickinson SL, Hermiston ML, Tighe RV, Steen RG, Small CG, Stoeckli ET, Keino-Masu K, Masu M, Rayburn H, Simons J, Bronson RT, Gordon JI, Tessier-Lavigne M, Weinberg RA, Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature. 1997 Apr 24;386(6627):796-804
2*J:29932 Fedtsova NG, Turner EE, Brn-3.0 expression identifies early post-mitotic CNS neurons and sensory neural precursors. Mech Dev. 1995 Nov;53(3):291-304
4J:232789 Feng J, Xian Q, Guan T, Hu J, Wang M, Huang Y, So KF, Evans SM, Chai G, Goffinet AM, Qu Y, Zhou L, Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons. Cereb Cortex. 2016 Jul;26(7):3323-34
1*J:154236 Feng W, Simoes-de-Souza F, Finger TE, Restrepo D, Williams T, Disorganized olfactory bulb lamination in mice deficient for transcription factor AP-2epsilon. Mol Cell Neurosci. 2009 Nov;42(3):161-71
5J:250440 Ferguson R, Serafeimidou-Pouliou E, Subramanian V, Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. J Anat. 2016 Dec;229(6):871-891
1J:248325 Figlia G, Norrmen C, Pereira JA, Gerber D, Suter U, Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system. Elife. 2017 Sep 07;6
1*J:73290 Figueiredo HF, Davis BM, Albers KM, Skin-derived nerve growth factor blocks programmed cell death in the trigeminal ganglia but does not enhance neuron proliferation. Mech Dev. 2001 Dec;109(2):205-14
2J:97663 Fiore R, Rahim B, Christoffels VM, Moorman AF, Puschel AW, Inactivation of the Sema5a gene results in embryonic lethality and defective remodeling of the cranial vascular system. Mol Cell Biol. 2005 Mar;25(6):2310-9
3J:46667 Fode C, Gradwohl G, Morin X, Dierich A, LeMeur M, Goridis C , Guillemot F, The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Neuron. 1998 Mar;20(3):483-94
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1J:178934 Freyer L, Aggarwal V, Morrow BE, Dual embryonic origin of the mammalian otic vesicle forming the inner ear. Development. 2011 Dec;138(24):5403-14
1J:204435 Freyer L, Nowotschin S, Pirity MK, Baldini A, Morrow BE, Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice. BMC Dev Biol. 2013 Aug 23;13(1):33
1J:102479 Fu AK, Ip FC, Fu WY, Cheung J, Wang JH, Yung WH, Ip NY, Aberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null mice. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15224-9
1J:167835 Fu J, Ivy Yu HM, Maruyama T, Mirando AJ, Hsu W, Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain development. Dev Dyn. 2011 Feb;240(2):365-71
1*J:151244 Fu X, Kiyama T, Li R, Russell M, Klein WH, Mu X, Epitope-tagging Math5 and Pou4f2: New tools to study retinal ganglion cell development in the mouse. Dev Dyn. 2009 May 20;238(9):2309-2317
1J:115047 Fu X, Sun H, Klein WH, Mu X, Beta-catenin is essential for lamination but not neurogenesis in mouse retinal development. Dev Biol. 2006 Nov 15;299(2):424-37
1J:155511 Fuchs P, Zorer M, Reipert S, Rezniczek GA, Propst F, Walko G, Fischer I, Bauer J, Leschnik MW, Luscher B, Thalhammer JG, Lassmann H, Wiche G, Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity. J Biol Chem. 2009 Sep 25;284(39):26502-9
1J:149918 Fuchs S, Herzog D, Sumara G, Buchmann-Moller S, Civenni G, Wu X, Chrostek-Grashoff A, Suter U, Ricci R, Relvas JB, Brakebusch C, Sommer L, Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1. Cell Stem Cell. 2009 Mar 6;4(3):236-47
3J:118795 Fuerst PG, Rauch SM, Burgess RW, Defects in eye development in transgenic mice overexpressing the heparan sulfate proteoglycan agrin. Dev Biol. 2007 Mar 1;303(1):165-80
4J:244596 Furlan A, Dyachuk V, Kastriti ME, Calvo-Enrique L, Abdo H, Hadjab S, Chontorotzea T, Akkuratova N, Usoskin D, Kamenev D, Petersen J, Sunadome K, Memic F, Marklund U, Fried K, Topilko P, Lallemend F, Kharchenko PV, Ernfors P, Adameyko I, Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla. Science. 2017 Jul 07;357(6346)
3J:223161 Gahring LC, Myers E, Palumbos S, Rogers SW, Nicotinic receptor Alpha7 expression during mouse adrenal gland development. PLoS One. 2014;9(8):e103861
1J:94049 Galceran J, Sustmann C, Hsu SC, Folberth S, Grosschedl R, LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis. Genes Dev. 2004 Nov 15;18(22):2718-23
1J:62070 Galili N, Nayak S, Epstein JA, Buck CA, Rnf4, a RING protein expressed in the developing nervous and reproductive systems, interacts with Gscl, a gene within the DiGeorge critical region. Dev Dyn. 2000 May;218(1):102-11
1*J:227617 Garrett AM, Jucius TJ, Sigaud LP, Tang FL, Xiong WC, Ackerman SL, Burgess RW, Analysis of Expression Pattern and Genetic Deletion of Netrin5 in the Developing Mouse. Front Mol Neurosci. 2016;9:3
3J:196589 Gatto G, Dudanova I, Suetterlin P, Davies AM, Drescher U, Bixby JL, Klein R, Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and branching by repressing TrkB and Ret signaling. J Neurosci. 2013 Mar 20;33(12):5399-410
1*J:43763 Gavalas A, Davenne M, Lumsden A, Chambon P, Rijli FM, Role of Hoxa-2 in axon pathfinding and rostral hindbrain patterning. Development. 1997 Oct;124(19):3693-702
1*J:46972 Gavalas A, Studer M, Lumsden A, Rijli FM, Krumlauf R, Chambon P, Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch. Development. 1998 Mar;125(6):1123-36
2J:266784 Gay MH, Valenta T, Herr P, Paratore-Hari L, Basler K, Sommer L, Distinct adhesion-independent functions of beta-catenin control stage-specific sensory neurogenesis and proliferation. BMC Biol. 2015 Apr 11;13:24
3J:97779 Genc B, Ozdinler PH, Mendoza AE, Erzurumlu RS, A chemoattractant role for NT-3 in proprioceptive axon guidance. PLoS Biol. 2004 Dec;2(12):e403
2*J:16389 Gendron-Maguire M, Mallo M, Zhang M, Gridley T, Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Cell. 1993 Dec 31;75(7):1317-31
1J:78726 Genoud S, Lappe-Siefke C, Goebbels S, Radtke F, Aguet M, Scherer SS, Suter U, Nave KA, Mantei N, Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol. 2002 Aug 19;158(4):709-18
1J:159105 Georgi SA, Reh TA, Dicer is required for the transition from early to late progenitor state in the developing mouse retina. J Neurosci. 2010 Mar 17;30(11):4048-61
1J:176956 Ghosh AS, Wang B, Pozniak CD, Chen M, Watts RJ, Lewcock JW, DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity. J Cell Biol. 2011 Sep 5;194(5):751-64
1J:43344 Ghyselinck NB, Dupe V, Dierich A, Messaddeq N, Garnier JM, Rochette-Egly C , Chambon P , Mark M, Role of the retinoic acid receptor beta (RARbeta) during mouse development. Int J Dev Biol. 1997 Jun;41(3):425-47
5J:60149 Giger RJ, Cloutier JF, Sahay A, Prinjha RK, Levengood DV, Moore SE, Pickering S, Simmons D, Rastan S, Walsh FS, Kolodkin AL, Ginty DD, Geppert M, Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins. Neuron. 2000 Jan;25(1):29-41
2J:91658 Gitler AD, Lu MM, Epstein JA, PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Dev Cell. 2004 Jul;7(1):107-16
1J:187622 Glasco DM, Sittaramane V, Bryant W, Fritzsch B, Sawant A, Paudyal A, Stewart M, Andre P, Cadete Vilhais-Neto G, Yang Y, Song MR, Murdoch JN, Chandrasekhar A, The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled. Dev Biol. 2012 Sep 15;369(2):211-22
2J:36235 Goddard JM, Rossel M, Manley NR, Capecchi MR, Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve. Development. 1996 Oct;122(10):3217-28
1J:174117 Gopal PP, Golden JA, Pax6-/- mice have a cell nonautonomous defect in nonradial interneuron migration. Cereb Cortex. 2008 Apr;18(4):752-62
1J:76787 Goshu E, Jin H, Fasnacht R, Sepenski M, Michaud JL, Fan CM, Sim2 mutants have developmental defects not overlapping with those of Sim1 mutants. Mol Cell Biol. 2002 Jun;22(12):4147-57
2J:273795 Gould TW, Dominguez B, de Winter F, Yeo GW, Liu P, Sundararaman B, Stark T, Vu A, Degen JL, Lin W, Lee KF, Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal. PLoS Genet. 2019 Mar;15(3):e1007948
2J:83744 Graef IA, Wang F, Charron F, Chen L, Neilson J, Tessier-Lavigne M, Crabtree GR, Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. Cell. 2003 May 30;113(5):657-70
4J:51674 Grbavec D, Lo R, Liu Y, Stifani S, Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy/Enhancer of split proteins, and is expressed during neuronal development. Eur J Biochem. 1998 Dec 1;258(2):339-49
1*J:82208 Greferath U, Canty AJ, Messenger J, Murphy M, Developmental expression of EphA4-tyrosine kinase receptor in the mouse brain and spinal cord. Mech Dev. 2002 Dec;119 Suppl 1:S231-8
1J:167409 Grimal S, Puech S, Wagener R, Venteo S, Carroll P, Fichard-Carroll A, Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells. Glia. 2010 Dec;58(16):1977-87
1J:138147 Gros-Louis F, Kriz J, Kabashi E, McDearmid J, Millecamps S, Urushitani M, Lin L, Dion P, Zhu Q, Drapeau P, Julien JP, Rouleau GA, Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish. Hum Mol Genet. 2008 Sep 1;17(17):2691-702
2J:93799 Gu C, Rodriguez ER, Reimert DV, Shu T, Fritzsch B, Richards LJ, Kolodkin AL, Ginty DD, Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev Cell. 2003 Jul;5(1):45-57
1J:95697 Gu C, Yoshida Y, Livet J, Reimert DV, Mann F, Merte J, Henderson CE, Jessell TM, Kolodkin AL, Ginty DD, Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science. 2005 Jan 14;307(5707):265-8
1J:152476 Gunnersen JM, Kuek A, Phipps JA, Hammond VE, Puthussery T, Fletcher EL, Tan SS, Seizure-related gene 6 (Sez-6) in amacrine cells of the rodent retina and the consequence of gene deletion. PLoS One. 2009;4(8):e6546
1J:67826 Guris DL, Fantes J, Tara D, Druker BJ, Imamoto A, Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome. Nat Genet. 2001 Mar;27(3):293-8
1J:69286 Haack H, Hynes RO, Integrin receptors are required for cell survival and proliferation during development of the peripheral glial lineage. Dev Biol. 2001 May 1;233(1):38-55
5J:78718 Haase G, Dessaud E, Garces A, de Bovis B, Birling M, Filippi P, Schmalbruch H, Arber S, deLapeyriere O, GDNF acts through PEA3 to regulate cell body positioning and muscle innervation of specific motor neuron pools. Neuron. 2002 Aug 29;35(5):893-905
2J:212572 Haddick PC, Tom I, Luis E, Quinones G, Wranik BJ, Ramani SR, Stephan JP, Tessier-Lavigne M, Gonzalez LC, Defining the ligand specificity of the deleted in colorectal cancer (DCC) receptor. PLoS One. 2014;9(1):e84823
1J:204192 Hadjab S, Franck MC, Wang Y, Sterzenbach U, Sharma A, Ernfors P, Lallemend F, A local source of FGF initiates development of the unmyelinated lineage of sensory neurons. J Neurosci. 2013 Nov 6;33(45):17656-66
3J:83128 Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestley JV, Averill S, King VR, Ball S, Peters J, Toda T, Yamamoto A, Hiraoka Y, Augustin M, Korthaus D, Wattler S, Wabnitz P, Dickneite C, Lampel S, Boehme F, Peraus G, Popp A, Rudelius M, Schlegel J, Fuchs H, de Angelis MH, Schiavo G, Shima DT, Russ AP, Stumm G, Martin JE, Fisher EM, Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science. 2003 May 2;300(5620):808-12
1J:39467 Hagino-Yamagishi K, Saijoh Y, Ikeda M, Ichikawa M, Minamikawa-Tachino R , Hamada H, Predominant expression of Brn-2 in the postmitotic neurons of the developing mouse neocortex. Brain Res. 1997 Mar 28;752(1-2):261-8
1J:88168 Hahm K, Sum EY, Fujiwara Y, Lindeman GJ, Visvader JE, Orkin SH, Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1. Mol Cell Biol. 2004 Mar;24(5):2074-82
1J:240526 Hall EA, Nahorski MS, Murray LM, Shaheen R, Perkins E, Dissanayake KN, Kristaryanto Y, Jones RA, Vogt J, Rivagorda M, Handley MT, Mali GR, Quidwai T, Soares DC, Keighren MA, McKie L, Mort RL, Gammoh N, Garcia-Munoz A, Davey T, Vermeren M, Walsh D, Budd P, Aligianis IA, Faqeih E, Quigley AJ, Jackson IJ, Kulathu Y, Jackson M, Ribchester RR, von Kriegsheim A, Alkuraya FS, Woods CG, Maher ER, Mill P, PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins. Am J Hum Genet. 2017 May 4;100(5):706-724
1J:165470 Hallock PT, Xu CF, Park TJ, Neubert TA, Curran T, Burden SJ, Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L. Genes Dev. 2010 Nov 1;24(21):2451-61
1J:176240 Hand R, Polleux F, Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum. Neural Dev. 2011;6:30
2*J:216140 Hanson MG, Fregoso VL, Vrana JD, Tucker CL, Niswander LA, Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders. Dev Biol. 2014 Nov 1;395(1):84-95
1J:231463 Haque K, Pandey AK, Zheng HW, Riazuddin S, Sha SH, Puligilla C, MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear. J Neurosci. 2016 Jan 27;36(4):1347-61
1J:167838 Harlow DE, Yang H, Williams T, Barlow LA, Epibranchial placode-derived neurons produce BDNF required for early sensory neuron development. Dev Dyn. 2011 Feb;240(2):309-23
2J:137254 Harrison SJ, Parrish M, Monaghan AP, Sall3 is required for the terminal maturation of olfactory glomerular interneurons. J Comp Neurol. 2008 Apr 10;507(5):1780-94
1*J:125514 Hartman BH, Hayashi T, Nelson BR, Bermingham-McDonogh O, Reh TA, Dll3 is expressed in developing hair cells in the mammalian cochlea. Dev Dyn. 2007 Oct;236(10):2875-83
1J:167107 Hartman BH, Nelson BR, Reh TA, Bermingham-McDonogh O, Delta/notch-like EGF-related receptor (DNER) is expressed in hair cells and neurons in the developing and adult mouse inner ear. J Assoc Res Otolaryngol. 2010 Jun;11(2):187-201
6*J:171311 Haupt C, Langhoff J, Huber AB, Adenylate Cyclase 1 modulates peripheral nerve branching patterns. Mol Cell Neurosci. 2010 Dec;45(4):439-48
1J:176192 Hayashi S, Rocancourt D, Buckingham M, Relaix F, Lack of In Vivo Functional Compensation Between Pax Family Groups II and III in Rodents. Mol Biol Evol. 2011 Oct;28(10):2787-98
1J:226761 He W, Bai G, Zhou H, Wei N, White NM, Lauer J, Liu H, Shi Y, Dumitru CD, Lettieri K, Shubayev V, Jordanova A, Guergueltcheva V, Griffin PR, Burgess RW, Pfaff SL, Yang XL, CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. Nature. 2015 Oct 29;526(7575):710-4
1J:99183 Heglind M, Cederberg A, Aquino J, Lucas G, Ernfors P, Enerback S, Lack of the central nervous system- and neural crest-expressed forkhead gene foxs1 affects motor function and body weight. Mol Cell Biol. 2005 Jul;25(13):5616-25
2*J:50514 Helmbacher F, Pujades C, Desmarquet C, Frain M, Rijli FM, Chambon P, Charnay P, Hoxa1 and Krox-20 synergize to control the development of rhombomere 3. Development. 1998 Dec;125(23):4739-48
3*J:62985 Helmbacher F, Schneider-Maunoury S, Topilko P, Tiret L, Charnay P, Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons. Development. 2000 Aug;127(15):3313-24
2*J:31706 Henkemeyer M, Marengere LE, McGlade J, Olivier JP, Conlon RA, Holmyard DP, Letwin K, Pawson T, Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis. Oncogene. 1994 Apr;9(4):1001-14
1J:47640 Herbarth B, Pingault V, Bondurand N, Kuhlbrodt K, Hermans-Borgmeyer I, Puliti A, Lemort N, Goossens M, Wegner M, Mutation of the Sry-related Sox10 gene in Dominant megacolon, a mouse model for human Hirschsprung disease. Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5161-5
4J:80082 Herbst R, Avetisova E, Burden SJ, Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor. Development. 2002 Dec;129(23):5449-60
1*J:99098 Hester M, Thompson JC, Mills J, Liu Y, El-Hodiri HM, Weinstein M, Smad1 and Smad8 function similarly in mammalian central nervous system development. Mol Cell Biol. 2005 Jun;25(11):4683-92
2J:160737 Heupel K, Sargsyan V, Plomp JJ, Rickmann M, Varoqueaux F, Zhang W, Krieglstein K, Loss of transforming growth factor-beta 2 leads to impairment of central synapse function. Neural Dev. 2008;3:25
1J:257443 Higashiyama H, Sumitomo H, Ozawa A, Igarashi H, Tsunekawa N, Kurohmaru M, Kanai Y, Anatomy of the Murine Hepatobiliary System: A Whole-Organ-Level Analysis Using a Transparency Method. Anat Rec (Hoboken). 2016 Feb;299(2):161-72
1*J:58691 Hildebrand JD, Soriano P, Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice. Cell. 1999 Nov 24;99(5):485-97
1J:171420 Hirai S, Banba Y, Satake T, Ohno S, Axon Formation in Neocortical Neurons Depends on Stage-Specific Regulation of Microtubule Stability by the Dual Leucine Zipper Kinase-c-Jun N-Terminal Kinase Pathway. J Neurosci. 2011 Apr 27;31(17):6468-80
1J:115575 Hirai S, Cui de F, Miyata T, Ogawa M, Kiyonari H, Suda Y, Aizawa S, Banba Y, Ohno S, The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex. J Neurosci. 2006 Nov 15;26(46):11992-2002
1*J:96323 Hirai S, Kawaguchi A, Suenaga J, Ono M, Cui de F, Ohno S, Expression of MUK/DLK/ZPK, an activator of the JNK pathway, in the nervous systems of the developing mouse embryo. Gene Expr Patterns. 2005 Apr;5(4):517-23
1J:71074 Hirata H, Tomita K, Bessho Y, Kageyama R, Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain. EMBO J. 2001 Aug 15;20(16):4454-66
1J:175565 Hirose M, Niewiadomski P, Tse G, Chi GC, Dong H, Lee A, Carpenter EM, Waschek JA, Pituitary adenylyl cyclase-activating peptide counteracts hedgehog-dependent motor neuron production in mouse embryonic stem cell cultures. J Neurosci Res. 2011 Sep;89(9):1363-74
3J:175786 Ho AT, Hayashi S, Brohl D, Aurade F, Rattenbach R, Relaix F, Neural Crest Cell Lineage Restricts Skeletal Muscle Progenitor Cell Differentiation through Neuregulin1-ErbB3 Signaling. Dev Cell. 2011 Aug 16;21(2):273-87
3J:126770 Hodge LK, Klassen MP, Han BX, Yiu G, Hurrell J, Howell A, Rousseau G, Lemaigre F, Tessier-Lavigne M, Wang F, Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron. 2007 Aug 16;55(4):572-86
1J:160258 Holley M, Rhodes C, Kneebone A, Herde MK, Fleming M, Steel KP, Emx2 and early hair cell development in the mouse inner ear. Dev Biol. 2010 Apr 15;340(2):547-56
1*J:161095 Hostikka SL, Gong J, Carpenter EM, Axial and appendicular skeletal transformations, ligament alterations, and motor neuron loss in Hoxc10 mutants. Int J Biol Sci. 2009;5(5):397-410
2J:83763 Hotta Y, Honda T, Naito M, Kuwano R, Developmental distribution of coxsackie virus and adenovirus receptor localized in the nervous system. Brain Res Dev Brain Res. 2003 Jun 12;143(1):1-13
5J:48411 Howard MJ, Gershon MD, Development of LBP110 expression by neural crest-derived enteric precursors: migration and differentiation potential in ls/ls mutant mice. J Neurobiol. 1998 Jun 15;35(4):341-54
2*J:42030 Hoyt PR, Bartholomew C, Davis AJ, Yutzey K, Gamer LW, Potter SS , Ihle JN , Mucenski ML, The Evi1 proto-oncogene is required at midgestation for neural, heart, and paraxial mesenchyme development. Mech Dev. 1997 Jul;65(1-2):55-70
4J:226479 Hua ZL, Emiliani FE, Nathans J, Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems. Neural Dev. 2015;10(1):21
8J:212111 Hua ZL, Jeon S, Caterina MJ, Nathans J, Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E3005-14
7J:207894 Hua ZL, Smallwood PM, Nathans J, Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons. Elife. 2013;2:e01482
2J:70744 Huang EJ, Liu W, Fritzsch B, Bianchi LM, Reichardt LF, Xiang M, Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. Development. 2001 Jul;128(13):2421-32
5*J:54178 Huang EJ, Wilkinson GA, Farinas I, Backus C, Zang K, Wong SL, Reichardt LF, Expression of Trk receptors in the developing mouse trigeminal ganglion: in vivo evidence for NT-3 activation of TrkA and TrkB in addition to TrkC. Development. 1999 May;126(10):2191-203
2J:182094 Huang ZP, Chen JF, Regan JN, Maguire CT, Tang RH, Dong XR, Majesky MW, Wang DZ, Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects. Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2575-86
1J:107594 Huber AB, Kania A, Tran TS, Gu C, De Marco Garcia N, Lieberam I, Johnson D, Jessell TM, Ginty DD, Kolodkin AL, Distinct roles for secreted semaphorin signaling in spinal motor axon guidance. Neuron. 2005 Dec 22;48(6):949-64
2J:178497 Huettl RE, Huber AB, Cranial nerve fasciculation and Schwann cell migration are impaired after loss of Npn-1. Dev Biol. 2011 Nov 15;359(2):230-41
2J:239624 Huettl RE, Huber AB, Characterizing Semaphorin-Mediated Effects on Sensory and Motor Axon Pathfinding and Connectivity During Embryonic Development. Methods Mol Biol. 2017;1493:443-466
3*J:242459 Huettl RE, Luxenhofer G, Bianchi E, Haupt C, Joshi R, Prochiantz A, Huber AB, Engrailed 1 mediates correct formation of limb innervation through two distinct mechanisms. PLoS One. 2015;10(2):e0118505
2J:170679 Huettl RE, Soellner H, Bianchi E, Novitch BG, Huber AB, Npn-1 contributes to axon-axon interactions that differentially control sensory and motor innervation of the limb. PLoS Biol. 2011 Feb;9(2):e1001020
1J:44094 Ikeya M, Lee SM, Johnson JE, McMahon AP, Takada S, Wnt signalling required for expansion of neural crest and CNS progenitors. Nature. 1997 Oct 30;389(6654):966-70
1J:126355 Imondi R, Jevince AR, Helms AW, Johnson JE, Kaprielian Z, Mis-expression of L1 on pre-crossing spinal commissural axons disrupts pathfinding at the ventral midline. Mol Cell Neurosci. 2007 Dec;36(4):462-71
1J:223126 Inman KE, Purcell P, Kume T, Trainor PA, Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia. PLoS Genet. 2013;9(12):e1003949
1*J:39345 Inoue T, Chisaka O, Matsunami H, Takeichi M, Cadherin-6 expression transiently delineates specific rhombomeres, other neural tube subdivisions, and neural crest subpopulations in mouse embryos. Dev Biol. 1997 Mar 15;183(2):183-94
2J:92220 Inoue T, Hatayama M, Tohmonda T, Itohara S, Aruga J, Mikoshiba K, Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives. Dev Biol. 2004 Jun 1;270(1):146-62
1J:162323 Inoue T, Kagawa T, Inoue-Mochita M, Isono K, Ohtsu N, Nobuhisa I, Fukushima M, Tanihara H, Taga T, Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis. FEBS Lett. 2010 Jul 16;584(14):3233-8
1J:122556 Inoue T, Ota M, Mikoshiba K, Aruga J, Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo. Dev Biol. 2007 Jun 15;306(2):669-84
1J:30431 Ishibashi M, Ang SL, Shiota K, Nakanishi S, Kageyama R, Guillemot F, Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects. Genes Dev. 1995 Dec 15;9(24):3136-48
1J:102844 Ishii M, Han J, Yen HY, Sucov HM, Chai Y, Maxson RE Jr, Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest. Development. 2005 Nov;132(22):4937-50
1J:144923 Islam SM, Shinmyo Y, Okafuji T, Su Y, Naser IB, Ahmed G, Zhang S, Chen S, Ohta K, Kiyonari H, Abe T, Tanaka S, Nishinakamura R, Terashima T, Kitamura T, Tanaka H, Draxin, a repulsive guidance protein for spinal cord and forebrain commissures. Science. 2009 Jan 16;323(5912):388-93
1J:131816 Iulianella A, Sharma M, Durnin M, Vanden Heuvel GB, Trainor PA, Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis. Development. 2008 Feb;135(4):729-41
1J:150348 Iulianella A, Sharma M, Vanden Heuvel GB, Trainor PA, Cux2 functions downstream of Notch signaling to regulate dorsal interneuron formation in the spinal cord. Development. 2009 Jul;136(14):2329-34
1J:250155 Iyer S, Chou FY, Wang R, Chiu HS, Raju VK, Little MH, Thomas WG, Piper M, Pennisi DJ, Crim1 has cell-autonomous and paracrine roles during embryonic heart development. Sci Rep. 2016 Jan 29;6:19832
2J:113326 Izmiryan A, Cheraud Y, Khanamiryan L, Leterrier JF, Federici T, Peltekian E, Moura-Neto V, Paulin D, Li Z, Xue ZG, Different expression of synemin isoforms in glia and neurons during nervous system development. Glia. 2006 Aug 15;54(3):204-13
1J:63720 Jacob J, Tiveron MC, Brunet JF, Guthrie S, Role of the target in the pathfinding of facial visceral motor axons. Mol Cell Neurosci. 2000 Jul;16(1):14-26
1J:34465 Jaegle M, Mandemakers W, Broos L, Zwart R, Karis A, Visser P , Grosveld F , Meijer D, The POU factor Oct-6 and Schwann cell differentiation. Science. 1996 26;273(5274):507-10
2J:235102 Jarrar W, Dias JM, Ericson J, Arnold HH, Holz A, Nkx2.2 and Nkx2.9 are the key regulators to determine cell fate of branchial and visceral motor neurons in caudal hindbrain. PLoS One. 2015;10(4):e0124408
1J:162558 Jaworski A, Long H, Tessier-Lavigne M, Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance. J Neurosci. 2010 Jul 14;30(28):9445-53
1J:131430 Jaworski DM, Soloway P, Caterina J, Falls WA, Tissue inhibitor of metalloproteinase-2(TIMP-2)-deficient mice display motor deficits. J Neurobiol. 2006 Jan;66(1):82-94
1J:89445 Jeong J, Mao J, Tenzen T, Kottmann AH, McMahon AP, Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev. 2004 Apr 15;18(8):937-51
1J:50975 Jhaveri S, Erzurumlu RS, Chiaia N, Kumar TR, Matzuk MM, Defective whisker follicles and altered brainstem patterns in activin and follistatin knockout mice. Mol Cell Neurosci. 1998 Nov;12(4-5):206-19
2J:112635 Ji SJ, Zhuang B, Falco C, Schneider A, Schuster-Gossler K, Gossler A, Sockanathan S, Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons. Dev Biol. 2006 Sep 1;297(1):249-61
1J:151918 Jiang H, Xiang M, Subtype specification of GABAergic amacrine cells by the orphan nuclear receptor Nr4a2/Nurr1. J Neurosci. 2009 Aug 19;29(33):10449-59
1J:133680 Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY, Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability. Nat Med. 2008 Apr;14(4):448-53
3J:226834 Jones I, Hagglund AC, Tornqvist G, Nord C, Ahlgren U, Carlsson L, A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development. Dis Model Mech. 2015 Dec 1;8(12):1517-29
2*J:133682 Jones NC, Lynn ML, Gaudenz K, Sakai D, Aoto K, Rey JP, Glynn EF, Ellington L, Du C, Dixon J, Dixon MJ, Trainor PA, Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function. Nat Med. 2008 Feb;14(2):125-33
3*J:11960 Julien JP, Meyer D, Flavell D, Hurst J, Grosveld F, Cloning and developmental expression of the murine neurofilament gene family. Brain Res Mol Brain Res. 1986 Dec;387(3):243-50
1J:167708 Jung Y, Kissil JL, McCarty JH, beta8 integrin and band 4.1B cooperatively regulate morphogenesis of the embryonic heart. Dev Dyn. 2011 Jan;240(1):271-7
1*J:132267 Junghans D, Heidenreich M, Hack I, Taylor V, Frotscher M, Kemler R, Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Eur J Neurosci. 2008 Feb;27(3):559-71
2J:41553 Jurata LW, Kenny DA, Gill GN, Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development. Proc Natl Acad Sci U S A. 1996 15;93(21):11693-8
1J:102289 Kablar B, Belliveau AC, Presence of neurotrophic factors in skeletal muscle correlates with survival of spinal cord motor neurons. Dev Dyn. 2005 Nov;234(3):659-69
4*J:54064 Kablar B, Rudnicki MA, Development in the absence of skeletal muscle results in the sequential ablation of motor neurons from the spinal cord to the brain. Dev Biol. 1999 Apr 1;208(1):93-109
1J:100037 Kablar B, Rudnicki MA, Information provided by the skeletal muscle and associated neurons is necessary for proper brain development. Int J Dev Neurosci. 2002 Nov;20(7):573-84
2J:119301 Kadison SR, Murakami F, Matise MP, Kaprielian Z, The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord. Dev Biol. 2006 Aug 15;296(2):499-513
1J:99328 Kameda Y, Mash1 is required for glomus cell formation in the mouse carotid body. Dev Biol. 2005 Jul 1;283(1):128-39
1J:116796 Kameda Y, Expression of glial progenitor markers p75(NTR) and S100 protein in the developing mouse parathyroid gland. Cell Tissue Res. 2007 Jan;327(1):15-23
2J:126876 Kameda Y, Nishimaki T, Chisaka O, Iseki S, Sucov HM, Expression of the epithelial marker E-cadherin by thyroid C cells and their precursors during murine development. J Histochem Cytochem. 2007 Oct;55(10):1075-88
2J:116627 Kameda Y, Nishimaki T, Miura M, Jiang SX, Guillemot F, Mash1 regulates the development of C cells in mouse thyroid glands. Dev Dyn. 2007 Jan;236(1):262-70
2J:267476 Kang DS, Yang YR, Lee C, Park B, Park KI, Seo JK, Seo YK, Cho H, Lucio C, Suh PG, Netrin-1/DCC-mediated PLCgamma1 activation is required for axon guidance and brain structure development. EMBO Rep. 2018 Nov;19(11)
2*J:63423 Kania A, Johnson RL, Jessell TM, Coordinate roles for LIM homeobox genes in directing the dorsoventral trajectory of motor axons in the vertebrate limb. Cell. 2000 Jul 21;102(2):161-73
2J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317
1*J:60094 Kanzler B, Foreman RK, Labosky PA, Mallo M, BMP signaling is essential for development of skeletogenic and neurogenic cranial neural crest. Development. 2000 Mar;127(5):1095-104
1J:148253 Kao TJ, Palmesino E, Kania A, SRC family kinases are required for limb trajectory selection by spinal motor axons. J Neurosci. 2009 Apr 29;29(17):5690-700
4J:138437 Kariya S, Park GH, Maeno-Hikichi Y, Leykekhman O, Lutz C, Arkovitz MS, Landmesser LT, Monani UR, Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy. Hum Mol Genet. 2008 Aug 15;17(16):2552-69
1J:213451 Karpinski BA, Maynard TM, Fralish MS, Nuwayhid S, Zohn IE, Moody SA, LaMantia AS, Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome. Dis Model Mech. 2014 Feb;7(2):245-57
1J:217098 Kaukua N, Shahidi MK, Konstantinidou C, Dyachuk V, Kaucka M, Furlan A, An Z, Wang L, Hultman I, Ahrlund-Richter L, Blom H, Brismar H, Lopes NA, Pachnis V, Suter U, Clevers H, Thesleff I, Sharpe P, Ernfors P, Fried K, Adameyko I, Glial origin of mesenchymal stem cells in a tooth model system. Nature. 2014 Sep 25;513(7519):551-4
4J:25959 Kawano H, Ohyama K, Kawamura K, Nagatsu I, Migration of dopaminergic neurons in the embryonic mesencephalon of mice. Brain Res Dev Brain Res. 1995 May 26;86(1-2):101-13
2*J:74243 Kawasaki T, Bekku Y, Suto F, Kitsukawa T, Taniguchi M, Nagatsu I, Nagatsu T, Itoh K, Yagi T, Fujisawa H, Requirement of neuropilin 1-mediated Sema3A signals in patterning of the sympathetic nervous system. Development. 2002 Feb;129(3):671-80
6J:32806 Keller-Peck CR, Mullen RJ, Patterns of neuronal differentiation in neural tube mutant mice: curly tail and Pax3 splotch-delayed. J Comp Neurol. 1996 May 13;368(4):516-26
2J:119015 Kellerer S, Schreiner S, Stolt CC, Scholz S, Bosl MR, Wegner M, Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence. Development. 2006 Aug;133(15):2875-86
2J:198828 Kelly CE, Thymiakou E, Dixon JE, Tanaka S, Godwin J, Episkopou V, Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. PLoS Biol. 2013;11(4):e1001538
2J:111886 Kennedy TE, Wang H, Marshall W, Tessier-Lavigne M, Axon guidance by diffusible chemoattractants: a gradient of netrin protein in the developing spinal cord. J Neurosci. 2006 Aug 23;26(34):8866-74
1J:169455 Kim D, Ackerman SL, The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons. J Neurosci. 2011 Feb 9;31(6):2167-79
2*J:251322 Kim M, Minoux M, Piaia A, Kueng B, Gapp B, Weber D, Haller C, Barbieri S, Namoto K, Lorenz T, Wirsching J, Bassilana F, Dietrich W, Rijli FM, Ksiazek I, DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect. Dev Biol. 2017 Nov 15;431(2):297-308
1J:218062 Kim N, Min KW, Kang KH, Lee EJ, Kim HT, Moon K, Choi J, Le D, Lee SH, Kim JW, Regulation of retinal axon growth by secreted Vax1 homeodomain protein. Elife. 2014;3:e02671
1J:74537 Kirby RJ, Zheng S, Tso P, Howles PN, Hui DY, Bile salt-stimulated carboxyl ester lipase influences lipoprotein assembly and secretion in intestine: a process mediated via ceramide hydrolysis. J Biol Chem. 2002 Feb 8;277(6):4104-9
1J:79871 Kitamura K, Yanazawa M, Sugiyama N, Miura H, Iizuka-Kogo A, Kusaka M, Omichi K, Suzuki R, Kato-Fukui Y, Kamiirisa K, Matsuo M, Kamijo S, Kasahara M, Yoshioka H, Ogata T, Fukuda T, Kondo I, Kato M, Dobyns WB, Yokoyama M, Morohashi K, Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans. Nat Genet. 2002 Nov;32(3):359-69
6J:44328 Kitsukawa T, Shimizu M, Sanbo M, Hirata T, Taniguchi M, Bekku Y , Yagi T , Fujisawa H, Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice. Neuron. 1997 Nov;19(5):995-1005
1*J:30346 Kitsukawa T, Shimono A, Kawakami A, Kondoh H, Fujisawa H, Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development. 1995 Dec;121(12):4309-18
1J:221642 Klingler E, Martin PM, Garcia M, Moreau-Fauvarque C, Falk J, Chareyre F, Giovannini M, Chedotal A, Girault JA, Goutebroze L, The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development. Development. 2015 Jun 1;142(11):2026-36
1J:128941 Ko SO, Chung IH, Xu X, Oka S, Zhao H, Cho ES, Deng C, Chai Y, Smad4 is required to regulate the fate of cranial neural crest cells. Dev Biol. 2007 Dec 1;312(1):435-47
4J:174461 Kobayashi K, Masuda T, Takahashi M, Miyazaki J, Nakagawa M, Uchigashima M, Watanabe M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K, Rho/Rho-kinase signaling pathway controls axon patterning of a specified subset of cranial motor neurons. Eur J Neurosci. 2011 Feb;33(4):612-21
1J:100207 Kobayashi K, Takahashi M, Matsushita N, Miyazaki J, Koike M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K, Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. J Neurosci. 2004 Apr 7;24(14):3480-8
1*J:76797 Kohlbecker A, Lee AE, Schorle H, Exencephaly in a subset of animals heterozygous for AP-2alpha mutation. Teratology. 2002 May;65(5):213-8
1J:152264 Koo SK, Hill JK, Hwang CH, Lin ZS, Millen KJ, Wu DK, Lmx1a maintains proper neurogenic, sensory, and non-sensory domains in the mammalian inner ear. Dev Biol. 2009 Sep 1;333(1):14-25
2*J:19219 Kostic D, Capecchi MR, Targeted disruptions of the murine Hoxa-4 and Hoxa-6 genes result in homeotic transformations of components of the vertebral column. Mech Dev. 1994 Jun;46(3):231-47
7J:110955 Kramer ER, Knott L, Su F, Dessaud E, Krull CE, Helmbacher F, Klein R, Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb. Neuron. 2006 Apr 6;50(1):35-47
1J:33038 Kramer R, Bucay N, Kane DJ, Martin LE, Tarpley JE, Theill LE, Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development. Proc Natl Acad Sci U S A. 1996 May 14;93(10):4833-8
2J:187871 Krebs LT, Bradley CK, Norton CR, Xu J, Oram KF, Starling C, Deftos ML, Bevan MJ, Gridley T, The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice. Genesis. 2012 Apr;50(4):366-74
2J:137720 Kubota Y, Hirashima M, Kishi K, Stewart CL, Suda T, Leukemia inhibitory factor regulates microvessel density by modulating oxygen-dependent VEGF expression in mice. J Clin Invest. 2008 Jul;118(7):2393-403
2J:177298 Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Okuno Y, Nakamura-Ishizu A, Sano K, Murakami M, Ema M, Omatsu Y, Takahashi S, Nagasawa T, Shibuya M, Okano H, Suda T, Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero. J Exp Med. 2011 May 9;208(5):949-60
2*J:169107 Kunwar AJ, Rickmann M, Backofen B, Browski SM, Rosenbusch J, Schoning S, Fleischmann T, Krieglstein K, Fischer von Mollard G, Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2575-80
1*J:106261 Kurohara K, Komatsu K, Kurisaki T, Masuda A, Irie N, Asano M, Sudo K, Nabeshima Y, Iwakura Y, Sehara-Fujisawa A, Essential roles of Meltrin beta (ADAM19) in heart development. Dev Biol. 2004 Mar 1;267(1):14-28
2J:229187 Kurosaka H, Trainor PA, Leroux-Berger M, Iulianella A, Cranial nerve development requires co-ordinated Shh and canonical Wnt signaling. PLoS One. 2015;10(3):e0120821
1*J:20160 Kurtz A, Zimmer A, Schnutgen F, Bruning G, Spener F, Muller T, The expression pattern of a novel gene encoding brain-fatty acid binding protein correlates with neuronal and glial cell development. Development. 1994 Sep;120(9):2637-49
2J:188362 Kuwajima T, Yoshida Y, Takegahara N, Petros TJ, Kumanogoh A, Jessell TM, Sakurai T, Mason C, Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing. Neuron. 2012 May 24;74(4):676-90
1J:127447 Kwiatkowski AV, Rubinson DA, Dent EW, Edward van Veen J, Leslie JD, Zhang J, Mebane LM, Philippar U, Pinheiro EM, Burds AA, Bronson RT, Mori S, Fassler R, Gertler FB, Ena/VASP Is Required for neuritogenesis in the developing cortex. Neuron. 2007 Nov 8;56(3):441-55
1J:189922 Lallemend F, Sterzenbach U, Hadjab-Lallemend S, Aquino JB, Castelo-Branco G, Sinha I, Villaescusa JC, Levanon D, Wang Y, Franck MC, Kharchenko O, Adameyko I, Linnarsson S, Groner Y, Turner E, Ernfors P, Positional differences of axon growth rates between sensory neurons encoded by Runx3. EMBO J. 2012 Sep 12;31(18):3718-29
3J:174591 Lamballe F, Genestine M, Caruso N, Arce V, Richelme S, Helmbacher F, Maina F, Pool-specific regulation of motor neuron survival by neurotrophic support. J Neurosci. 2011 Aug 3;31(31):11144-58
1J:245768 Landry-Truchon K, Houde N, Boucherat O, Joncas FH, Dasen JS, Philippidou P, Mansfield JH, Jeannotte L, HOXA5 plays tissue-specific roles in the developing respiratory system. Development. 2017 Oct 01;144(19):3547-3561
1J:258315 Langhorst H, Juttner R, Groneberg D, Mohtashamdolatshahi A, Pelz L, Purfurst B, Schmidt-Ott KM, Friebe A, Rathjen FG, The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice. Dis Model Mech. 2018 Feb 22;11(2)
1J:270401 Latremoliere A, Cheng L, DeLisle M, Wu C, Chew S, Hutchinson EB, Sheridan A, Alexandre C, Latremoliere F, Sheu SH, Golidy S, Omura T, Huebner EA, Fan Y, Whitman MC, Nguyen E, Hermawan C, Pierpaoli C, Tischfield MA, Woolf CJ, Engle EC, Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration. Cell Rep. 2018 Aug 14;24(7):1865-1879.e9
2J:228865 Law C, Schaan Profes M, Levesque M, Kaltschmidt JA, Verhage M, Kania A, Normal Molecular Specification and Neurodegenerative Disease-Like Death of Spinal Neurons Lacking the SNARE-Associated Synaptic Protein Munc18-1. J Neurosci. 2016 Jan 13;36(2):561-76
3J:73497 Lawoko-Kerali G, Rivolta MN, Holley M, Expression of the transcription factors GATA3 and Pax2 during development of the mammalian inner ear. J Comp Neurol. 2002 Jan 21;442(4):378-91
1J:142576 Lebeurrier N, Launay S, Macrez R, Maubert E, Legros H, Leclerc A, Jamin SP, Picard JY, Marret S, Laudenbach V, Berger P, Sonderegger P, Ali C, di Clemente N, Vivien D, Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin. J Cell Sci. 2008 Oct 15;121(Pt 20):3357-65
2J:113043 Lee EY, Hu N, Yuan SS, Cox LA, Bradley A, Lee WH, Herrup K, Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 1994 Sep 1;8(17):2008-21
1J:100591 Lee HY, Wroblewski E, Philips GT, Stair CN, Conley K, Reedy M, Mastick GS, Brown NL, Multiple requirements for Hes 1 during early eye formation. Dev Biol. 2005 Aug 15;284(2):464-78
3J:241012 Lee M, Yoon J, Song H, Lee B, Lam DT, Yoon J, Baek K, Clevers H, Jeong Y, Tcf7l2 plays crucial roles in forebrain development through regulation of thalamic and habenular neuron identity and connectivity. Dev Biol. 2017 Apr 01;424(1):62-76
2J:155064 Lee S, Lee B, Lee JW, Lee SK, Retinoid signaling and neurogenin2 function are coupled for the specification of spinal motor neurons through a chromatin modifier CBP. Neuron. 2009 Jun 11;62(5):641-54
1J:96395 Lee S, Walker CL, Karten B, Kuny SL, Tennese AA, O'Neill MA, Wevrick R, Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth. Hum Mol Genet. 2005 Mar 1;14(5):627-37
1J:200273 Legate KR, Montag D, Bottcher RT, Takahashi S, Fassler R, Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Igamma in vivo. J Cell Sci. 2012 Dec 1;125(Pt 23):5636-46
2J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535
2*J:62022 Leitges M, Neidhardt L, Haenig B, Herrmann BG, Kispert A, The paired homeobox gene Uncx4.1 specifies pedicles, transverse processes and proximal ribs of the vertebral column. Development. 2000 Jun;127(11):2259-67
2J:79981 Leonova EV, Lomax MI, Expression of the mouse Macf2 gene during inner ear development. Brain Res Mol Brain Res. 2002 Sep 30;105(1-2):67-78
4J:242741 Leung V, Iliescu A, Jolicoeur C, Gravel M, Apuzzo S, Torban E, Cayouette M, Gros P, The planar cell polarity protein Vangl2 is required for retinal axon guidance. Dev Neurobiol. 2016 Feb;76(2):150-65
1J:154593 Levin MD, Lu MM, Petrenko NB, Hawkins BJ, Gupta TH, Lang D, Buckley PT, Jochems J, Liu F, Spurney CF, Yuan LJ, Jacobson JT, Brown CB, Huang L, Beermann F, Margulies KB, Madesh M, Eberwine JH, Epstein JA, Patel VV, Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers. J Clin Invest. 2009 Nov;119(11):3420-36
1J:226395 Lewis AE, Hwa J, Wang R, Soriano P, Bush JO, Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature. Dev Biol. 2015 Oct 15;406(2):186-95
1J:195048 Li W, Kohara H, Uchida Y, James JM, Soneji K, Cronshaw DG, Zou YR, Nagasawa T, Mukouyama YS, Peripheral nerve-derived CXCL12 and VEGF-A regulate the patterning of arterial vessel branching in developing limb skin. Dev Cell. 2013 Feb 25;24(4):359-71
1J:104339 Li X, Perissi V, Liu F, Rose DW, Rosenfeld MG, Tissue-specific regulation of retinal and pituitary precursor cell proliferation. Science. 2002 Aug 16;297(5584):1180-3
1J:216613 Liang D, Wang X, Mittal A, Dhiman S, Hou SY, Degenhardt K, Astrof S, Mesodermal expression of integrin alpha5beta1 regulates neural crest development and cardiovascular morphogenesis. Dev Biol. 2014 Nov 15;395(2):232-44
3J:101029 Lieberam I, Agalliu D, Nagasawa T, Ericson J, Jessell TM, A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons. Neuron. 2005 Sep 1;47(5):667-79
1J:226755 Lim JW, Donahoo AL, Bunt J, Edwards TJ, Fenlon LR, Liu Y, Zhou J, Moldrich RX, Piper M, Gobius I, Bailey TL, Wray NR, Kessaris N, Poo MM, Rubenstein JL, Richards LJ, EMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex. Development. 2015 Nov 1;142(21):3746-57
1J:62552 Lim KC, Lakshmanan G, Crawford SE, Gu Y, Grosveld F, Engel JD, Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system. Nat Genet. 2000 Jun;25(2):209-12
1J:166964 Lin L, Lee VM, Wang Y, Lin JS, Sock E, Wegner M, Lei L, Sox11 regulates survival and axonal growth of embryonic sensory neurons. Dev Dyn. 2011 Jan;240(1):52-64
1J:99854 Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF, Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron. 2005 May 19;46(4):569-79
2J:60191 Lin W, Sanchez HB, Deerinck T, Morris JK, Ellisman M, Lee KF, Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice. Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1299-304
2J:213772 Liu C, Lin C, Gao C, May-Simera H, Swaroop A, Li T, Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a. Biol Open. 2014;3(9):861-70
1*J:154795 Liu H, Shafey D, Moores JN, Kothary R, Neurodevelopmental consequences of Smn depletion in a mouse model of spinal muscular atrophy. J Neurosci Res. 2010 Jan;88(1):111-22
1J:241238 Liu X, Uemura A, Fukushima Y, Yoshida Y, Hirashima M, Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1. Cell Rep. 2016 Nov 22;17(9):2299-2311
3*J:149227 Liu Y, Oppenheim RW, Sugiura Y, Lin W, Abnormal development of the neuromuscular junction in Nedd4-deficient mice. Dev Biol. 2009 Jun 1;330(1):153-66
1J:134988 Liu Y, Padgett D, Takahashi M, Li H, Sayeed A, Teichert RW, Olivera BM, McArdle JJ, Green WN, Lin W, Essential roles of the acetylcholine receptor {gamma}-subunit in neuromuscular synaptic patterning. Development. 2008 Jun;135(11):1957-67
4J:273796 Liu Y, Sugiura Y, Chen F, Lee KF, Ye Q, Lin W, Blocking skeletal muscle DHPRs/Ryr1 prevents neuromuscular synapse loss in mutant mice deficient in type III Neuregulin 1 (CRD-Nrg1). PLoS Genet. 2019 Mar;15(3):e1007857
5J:185422 Liu Y, Sugiura Y, Wu F, Mi W, Taketo MM, Cannon S, Carroll T, Lin W, beta-Catenin stabilization in skeletal muscles, but not in motor neurons, leads to aberrant motor innervation of the muscle during neuromuscular development in mice. Dev Biol. 2012 Jun 15;366(2):255-67
2J:89780 Long H, Sabatier C, Ma L, Plump A, Yuan W, Ornitz DM, Tamada A, Murakami F, Goodman CS, Tessier-Lavigne M, Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Neuron. 2004 Apr 22;42(2):213-23
3*J:76363 Lonze BE, Riccio A, Cohen S, Ginty DD, Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron. 2002 Apr 25;34(3):371-85
2J:208651 Louvi A, Nishimura S, Gunel M, Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration. Development. 2014 Mar;141(6):1404-15
1J:177911 Lu PP, Ramanan N, Serum response factor is required for cortical axon growth but is dispensable for neurogenesis and neocortical lamination. J Neurosci. 2011 Nov 16;31(46):16651-64
1*J:93897 Lu W, Yamamoto V, Ortega B, Baltimore D, Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth. Cell. 2004 Oct 1;119(1):97-108
1*J:29061 Luo J, Pasceri P, Conlon RA, Rossant J, Giguere V, Mice lacking all isoforms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid. Mech Dev. 1995 Sep;53(1):61-71
1J:176643 Luria V, Krawchuk D, Jessell TM, Laufer E, Kania A, Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb. Neuron. 2008 Dec 26;60(6):1039-53
2J:160874 Luria V, Laufer E, Lateral motor column axons execute a ternary trajectory choice between limb and body tissues. Neural Dev. 2007;2:13
1J:73776 Lutolf S, Radtke F, Aguet M, Suter U, Taylor V, Notch1 is required for neuronal and glial differentiation in the cerebellum. Development. 2002 Jan;129(2):373-85
4J:203998 Luxey M, Jungas T, Laussu J, Audouard C, Garces A, Davy A, Eph:ephrin-B1 forward signaling controls fasciculation of sensory and motor axons. Dev Biol. 2013 Nov 15;383(2):264-74
3J:122797 Ma L, Tessier-Lavigne M, Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons. J Neurosci. 2007 Jun 20;27(25):6843-51
1J:221029 Ma YC, Song MR, Park JP, Henry Ho HY, Hu L, Kurtev MV, Zieg J, Ma Q, Pfaff SL, Greenberg ME, Regulation of motor neuron specification by phosphorylation of neurogenin 2. Neuron. 2008 Apr 10;58(1):65-77
1J:185466 Macdonald JI, Dietrich A, Gamble S, Hryciw T, Grant RI, Meakin SO, Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons. J Neurochem. 2012 Jun;121(6):861-880
2J:229604 Machon O, Masek J, Machonova O, Krauss S, Kozmik Z, Meis2 is essential for cranial and cardiac neural crest development. BMC Dev Biol. 2015;15:40
2J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98
2J:215515 Magnani D, Hasenpusch-Theil K, Theil T, Gli3 controls subplate formation and growth of cortical axons. Cereb Cortex. 2013 Nov;23(11):2542-51
2J:165607 Maklad A, Conway M, Hodges C, Hansen LA, Development of innervation to maxillary whiskers in mice. Anat Rec (Hoboken). 2010 Sep;293(9):1553-67
1J:145069 Maklad A, Nicolai JR, Bichsel KJ, Evenson JE, Lee TC, Threadgill DW, Hansen LA, The EGFR is required for proper innervation to the skin. J Invest Dermatol. 2009 Mar;129(3):690-8
1J:227021 Mallika C, Guo Q, Li JY, Gbx2 is essential for maintaining thalamic neuron identity and repressing habenular characters in the developing thalamus. Dev Biol. 2015 Nov 1;407(1):26-39
2J:154926 Mandai K, Guo T, St Hillaire C, Meabon JS, Kanning KC, Bothwell M, Ginty DD, LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development. Neuron. 2009 Sep 10;63(5):614-27
4J:210221 Mandai K, Reimert DV, Ginty DD, Linx mediates interaxonal interactions and formation of the internal capsule. Neuron. 2014 Jul 2;83(1):93-103
2*J:45337 Manley NR, Capecchi MR, Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. Dev Biol. 1997 Dec 15;192(2):274-88
2*J:4501 Mansour SL, Goddard JM, Capecchi MR, Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development. 1993 Jan;117(1):13-28
1*J:63181 Manzanares M, Trainor PA, Ariza-McNaughton L, Nonchev S, Krumlauf R, Dorsal patterning defects in the hindbrain, roof plate and skeleton in the dreher (dr(J)) mouse mutant. Mech Dev. 2000 Jun;94(1-2):147-56
1J:141248 Mao CA, Wang SW, Pan P, Klein WH, Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5. Development. 2008 Oct;135(20):3379-88
1J:198541 Maor-Nof M, Homma N, Raanan C, Nof A, Hirokawa N, Yaron A, Axonal pruning is actively regulated by the microtubule-destabilizing protein kinesin superfamily protein 2A. Cell Rep. 2013 Apr 25;3(4):971-7
2J:163657 Mar L, Rivkin E, Kim DY, Yu JY, Cordes SP, A genetic screen for mutations that affect cranial nerve development in the mouse. J Neurosci. 2005 Dec 14;25(50):11787-95
2J:159208 Marchong MN, Yurkowski C, Ma C, Spencer C, Pajovic S, Gallie BL, Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death. PLoS Genet. 2010;6(4):e1000923
2J:220152 Marcos S, Nieto-Lopez F, Sandonis A, Cardozo MJ, Di Marco F, Esteve P, Bovolenta P, Secreted frizzled related proteins modulate pathfinding and fasciculation of mouse retina ganglion cell axons by direct and indirect mechanisms. J Neurosci. 2015 Mar 18;35(11):4729-40
2*J:15280 Mark M, Lufkin T, Vonesch JL, Ruberte E, Olivo JC, Dolle P, Gorry P, Lumsden A, Chambon P, Two rhombomeres are altered in Hoxa-1 mutant mice. Development. 1993 Oct;119(2):319-38
2J:123223 Markham K, Schuurmans C, Weiss S, STAT5A/B activity is required in the developing forebrain and spinal cord. Mol Cell Neurosci. 2007 Jun;35(2):272-82
1J:201060 Marques L, Thorsteinsdottir S, Dynamics of Akt activation during mouse embryo development: Distinct subcellular patterns distinguish proliferating versus differentiating cells. Differentiation. 2013 Jul-Sep;86(1-2):48-56
1J:231817 Matsumoto S, Kiryu-Seo S, Kiyama H, Motor Nerve Arborization Requires Proteolytic Domain of Damage-Induced Neuronal Endopeptidase (DINE) during Development. J Neurosci. 2016 Apr 27;36(17):4744-57
1J:121105 Matsumoto Y, Irie F, Inatani M, Tessier-Lavigne M, Yamaguchi Y, Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate. J Neurosci. 2007 Apr 18;27(16):4342-50
6*J:81673 Mbiene JP, Roberts JD, Distribution of keratin 8-containing cell clusters in mouse embryonic tongue: Evidence for a prepattern for taste bud development. J Comp Neurol. 2003 Mar 3;457(2):111-22
3*J:148803 McCulloch DR, Le Goff C, Bhatt S, Dixon LJ, Sandy JD, Apte SS, Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues. Gene Expr Patterns. 2009 Jun;9(5):314-23
1J:74989 McEvilly RJ, de Diaz MO, Schonemann MD, Hooshmand F, Rosenfeld MG, Transcriptional regulation of cortical neuron migration by POU domain factors. Science. 2002 Feb 22;295(5559):1528-32
3*J:19631 McKay IJ, Muchamore I, Krumlauf R, Maden M, Lumsden A, Lewis J, The kreisler mouse: a hindbrain segmentation mutant that lacks two rhombomeres. Development. 1994 Aug;120(8):2199-211
1J:160714 McNeill EM, Roos KP, Moechars D, Clagett-Dame M, Nav2 is necessary for cranial nerve development and blood pressure regulation. Neural Dev. 2010;5:6
1J:179882 Mead TJ, Yutzey KE, Notch pathway regulation of neural crest cell development in vivo. Dev Dyn. 2012 Feb;241(2):376-89
1*J:83936 Mechta-Grigoriou F, Giudicelli F, Pujades C, Charnay P, Yaniv M, c-jun regulation and function in the developing hindbrain. Dev Biol. 2003 Jun 15;258(2):419-31
1*J:62577 Medina-Martinez O, Bradley A, Ramirez-Solis R, A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations. Dev Biol. 2000 Jun 1;222(1):71-83
3J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92
2J:235721 Menuchin-Lasowski Y, Oren-Giladi P, Xie Q, Ezra-Elia R, Ofri R, Peled-Hajaj S, Farhy C, Higashi Y, Van de Putte T, Kondoh H, Huylebroeck D, Cvekl A, Ashery-Padan R, Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals. Development. 2016 Aug 1;143(15):2829-41
1J:92632 Menzies AS, Aszodi A, Williams SE, Pfeifer A, Wehman AM, Goh KL, Mason CA, Fassler R, Gertler FB, Mena and vasodilator-stimulated phosphoprotein are required for multiple actin-dependent processes that shape the vertebrate nervous system. J Neurosci. 2004 Sep 15;24(37):8029-38
1*J:78406 Merlo GR, Paleari L, Mantero S, Zerega B, Adamska M, Rinkwitz S, Bober E, Levi G, The Dlx5 homeobox gene is essential for vestibular morphogenesis in the mouse embryo through a BMP4-mediated pathway. Dev Biol. 2002 Aug 1;248(1):157-69
3J:221340 Messeant J, Dobbertin A, Girard E, Delers P, Manuel M, Mangione F, Schmitt A, Le Denmat D, Molgo J, Zytnicki D, Schaeffer L, Legay C, Strochlic L, MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance. J Neurosci. 2015 Mar 25;35(12):4926-41
1*J:29971 Meyer D, Birchmeier C, Multiple essential functions of neuregulin in development [see comments] [published erratum appears in Nature 1995 Dec 14;378(6558):753]. Nature. 1995 Nov 23;378(6555):386-90
1*J:43309 Meyer D, Yamaai T, Garratt A, Riethmacher-Sonnenberg E, Kane D , Theill LE , Birchmeier C, Isoform-specific expression and function of neuregulin. Development. 1997 Sep;124(18):3575-86
1*J:87726 Milewski RC, Chi NC, Li J, Brown C, Lu MM, Epstein JA, Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3. Development. 2004 Feb;131(4):829-37
2J:92188 Millen KJ, Millonig JH, Hatten ME, Roof plate and dorsal spinal cord dl1 interneuron development in the dreher mutant mouse. Dev Biol. 2004 Jun 15;270(2):382-92
1J:198637 Minchin JE, Williams VC, Hinits Y, Low S, Tandon P, Fan CM, Rawls JF, Hughes SM, Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion. Development. 2013 Jul;140(14):2972-84
3J:242980 Mitsogiannis MD, Little GE, Mitchell KJ, Semaphorin-Plexin signaling influences early ventral telencephalic development and thalamocortical axon guidance. Neural Dev. 2017 Apr 24;12(1):6
1J:109570 Miura E, Fukaya M, Sato T, Sugihara K, Asano M, Yoshioka K, Watanabe M, Expression and distribution of JNK/SAPK-associated scaffold protein JSAP1 in developing and adult mouse brain. J Neurochem. 2006 Jun;97(5):1431-46
1J:185648 Mizuguchi R, Naritsuka H, Mori K, Yoshihara Y, Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb. J Neurosci. 2012 Jun 27;32(26):8831-44
1J:175241 Mohseni P, Sung HK, Murphy AJ, Laliberte CL, Pallari HM, Henkelman M, Georgiou J, Xie G, Quaggin SE, Thorner PS, Eriksson JE, Nagy A, Nestin Is Not Essential for Development of the CNS But Required for Dispersion of Acetylcholine Receptor Clusters at the Area of Neuromuscular Junctions. J Neurosci. 2011 Aug 10;31(32):11547-11552
6J:95075 Molin DG, Poelmann RE, DeRuiter MC, Azhar M, Doetschman T, Gittenberger-de Groot AC, Transforming growth factor beta-SMAD2 signaling regulates aortic arch innervation and development. Circ Res. 2004 Nov 26;95(11):1109-17
1J:173574 Monk KR, Oshima K, Jors S, Heller S, Talbot WS, Gpr126 is essential for peripheral nerve development and myelination in mammals. Development. 2011 Jul;138(13):2673-80
1J:149312 Moran JL, Shifley ET, Levorse JM, Mani S, Ostmann K, Perez-Balaguer A, Walker DM, Vogt TF, Cole SE, Manic fringe is not required for embryonic development, and fringe family members do not exhibit redundant functions in the axial skeleton, limb, or hindbrain. Dev Dyn. 2009 May 28;238(7):1803-1812
1J:119026 Morcillo J, Martinez-Morales JR, Trousse F, Fermin Y, Sowden JC, Bovolenta P, Proper patterning of the optic fissure requires the sequential activity of BMP7 and SHH. Development. 2006 Aug;133(16):3179-90
1J:226687 Morello F, Prasad AA, Rehberg K, Vieira de Sa R, Anton-Bolanos N, Leyva-Diaz E, Adolfs Y, Tissir F, Lopez-Bendito G, Pasterkamp RJ, Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development. J Neurosci. 2015 Oct 21;35(42):14205-19
2J:272917 Moreno-Bravo JA, Roig Puiggros S, Mehlen P, Chedotal A, Synergistic Activity of Floor-Plate- and Ventricular-Zone-Derived Netrin-1 in Spinal Cord Commissural Axon Guidance. Neuron. 2019 Feb 20;101(4):625-634.e3
1*J:88577 Mu X, Beremand PD, Zhao S, Pershad R, Sun H, Scarpa A, Liang S, Thomas TL, Klein WH, Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Development. 2004 Mar;131(6):1197-210
3J:146349 Mu X, Fu X, Beremand PD, Thomas TL, Klein WH, Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2. Proc Natl Acad Sci U S A. 2008 May 13;105(19):6942-7
1J:97089 Mu X, Fu X, Sun H, Liang S, Maeda H, Frishman LJ, Klein WH, Ganglion cells are required for normal progenitor- cell proliferation but not cell-fate determination or patterning in the developing mouse retina. Curr Biol. 2005 Mar 29;15(6):525-30
2J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50
1J:98488 Mui SH, Kim JW, Lemke G, Bertuzzi S, Vax genes ventralize the embryonic eye. Genes Dev. 2005 May 15;19(10):1249-59
2J:64754 Mulder GB, Manley N, Grant J, Schmidt K, Zeng W, Eckhoff C, Maggio-Price L, Effects of excess vitamin A on development of cranial neural crest-derived structures: A neonatal and embryologic study. Teratology. 2000 Oct;62(4):214-26
1J:52258 Mulder GB, Manley N, Maggio-Price L, Retinoic acid-induced thymic abnormalities in the mouse are associated with altered pharyngeal morphology, thymocyte maturation defects, and altered expression of Hoxa3 and Pax1. Teratology. 1998 Dec;58(6):263-75
1J:86051 Muller M, Jabs N, Lork DE, Fritzsch B, Sander M, Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons. Development. 2003 Dec;130(23):5815-26
1*J:191199 Mulvaney JF, Yatteau A, Sun WW, Jacques B, Takubo K, Suda T, Yamada W, Dabdoub A, Secreted Factor R-Spondin 2 is Involved in Refinement of Patterning of the Mammalian Cochlea. Dev Dyn. 2013 Feb;242(2):179-88
1J:170647 Mundell NA, Labosky PA, Neural crest stem cell multipotency requires Foxd3 to maintain neural potential and repress mesenchymal fates. Development. 2011 Feb;138(4):641-52
1J:143162 Murata J, Tokunaga A, Okano H, Kubo T, Mapping of notch activation during cochlear development in mice: implications for determination of prosensory domain and cell fate diversification. J Comp Neurol. 2006 Jul 20;497(3):502-18
1J:59183 Nakamura Y, Sakakibara Si, Miyata T, Ogawa M, Shimazaki T, Weiss S, Kageyama R, Okano H, The bHLH gene hes1 as a repressor of the neuronal commitment of CNS stem cells. J Neurosci. 2000 Jan 1;20(1):283-93
1J:213066 Namba T, Kibe Y, Funahashi Y, Nakamuta S, Takano T, Ueno T, Shimada A, Kozawa S, Okamoto M, Shimoda Y, Oda K, Wada Y, Masuda T, Sakakibara A, Igarashi M, Miyata T, Faivre-Sarrailh C, Takeuchi K, Kaibuchi K, Pioneering axons regulate neuronal polarization in the developing cerebral cortex. Neuron. 2014 Feb 19;81(4):814-29
1*J:55705 Nardelli J, Thiesson D, Fujiwara Y, Tsai FY, Orkin SH, Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Dev Biol. 1999 Jun 15;210(2):305-21
1J:21480 Narisawa S, Hasegawa H, Watanabe K, Millan JL, Stage-specific expression of alkaline phosphatase during neural development in the mouse. Dev Dyn. 1994 Nov;201(3):227-35
3J:156992 Nawabi H, Briancon-Marjollet A, Clark C, Sanyas I, Takamatsu H, Okuno T, Kumanogoh A, Bozon M, Takeshima K, Yoshida Y, Moret F, Abouzid K, Castellani V, A midline switch of receptor processing regulates commissural axon guidance in vertebrates. Genes Dev. 2010 Feb 15;24(4):396-410
1J:83133 Nemer G, Nemer M, Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6. Dev Biol. 2003 Feb 1;254(1):131-48
1J:102348 Nery S, Corbin JG, Fishell G, Dlx2 progenitor migration in wild type and Nkx2.1 mutant telencephalon. Cereb Cortex. 2003 Sep;13(9):895-903
1J:80416 Nery S, Fishell G, Corbin JG, The caudal ganglionic eminence is a source of distinct cortical and subcortical cell populations. Nat Neurosci. 2002 Dec;5(12):1279-87
10J:264453 Newbern JM, Li X, Shoemaker SE, Zhou J, Zhong J, Wu Y, Bonder D, Hollenback S, Coppola G, Geschwind DH, Landreth GE, Snider WD, Specific functions for ERK/MAPK signaling during PNS development. Neuron. 2011 Jan 13;69(1):91-105
1J:63216 Nguyen M, Arnheiter H, Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF. Development. 2000 Aug;127(16):3581-91
2J:171528 Nie X, Wang Q, Jiao K, Dicer activity in neural crest cells is essential for craniofacial organogenesis and pharyngeal arch artery morphogenesis. Mech Dev. 2011 Mar-Apr;128(3-4):200-7
1J:82804 Niederreither K, Vermot J, Le Roux I, Schuhbaur B, Chambon P, Dolle P, The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system. Development. 2003 Jun;130(11):2525-34
1*J:53473 Niederreither K, Vermot J, Schuhbaur B, Chambon P, Dolle P, Retinoic acid synthesis and hindbrain patterning in the mouse embryo. Development. 2000 Jan;127(1):75-85
2J:37005 Noakes PG, Phillips WD, Hanley TA, Sanes JR, Merlie JP, 43K protein and acetylcholine receptors colocalize during the initial stages of neuromuscular synapse formation in vivo. Dev Biol. 1991;155(1):275-80
5J:57885 O'Connor R, Tessier-Lavigne M, Identification of maxillary factor, a maxillary process-derived chemoattractant for developing trigeminal sensory axons. Neuron. 1999 Sep;24(1):165-78
1*J:63771 Offenhauser N, Santolini E, Simeone A, Di Fiore PP, Differential patterns of expression of eps15 and Eps15R during mouse embryogenesis. Mech Dev. 2000 Jul;95(1-2):309-12
7J:207212 Oh WJ, Gu C, Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism. Neuron. 2013 Oct 16;80(2):458-69
1J:135129 Ohshima T, Hirasawa M, Tabata H, Mutoh T, Adachi T, Suzuki H, Saruta K, Iwasato T, Itohara S, Hashimoto M, Nakajima K, Ogawa M, Kulkarni AB, Mikoshiba K, Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development. 2007 Jun;134(12):2273-82
3J:76685 Ohshima T, Ogawa M, Takeuchi K, Takahashi S, Kulkarni AB, Mikoshiba K, Cyclin-dependent kinase 5/p35 contributes synergistically with Reelin/Dab1 to the positioning of facial branchiomotor and inferior olive neurons in the developing mouse hindbrain. J Neurosci. 2002 May 15;22(10):4036-44
1J:92785 Ohtoshi A, Behringer RR, Neonatal lethality, dwarfism, and abnormal brain development in Dmbx1 mutant mice. Mol Cell Biol. 2004 Sep;24(17):7548-58
3J:48402 Ohyama K, Kawano H, Asou H, Fukuda T, Oohira A, Uyemura K, Kawamura K, Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice. Brain Res Dev Brain Res. 1998 May 15;107(2):219-26
2J:44398 Ohyama K, Kawano H, Kawamura K, Localization of extracellular matrix molecules, integrins and their regulators, TGF betas, is correlated with axon pathfinding in the spinal cord of normal and Danforth's short tail mice. Brain Res Dev Brain Res. 1997 Nov 12;103(2):143-54
2J:110011 Okada K, Inoue A, Okada M, Murata Y, Kakuta S, Jigami T, Kubo S, Shiraishi H, Eguchi K, Motomura M, Akiyama T, Iwakura Y, Higuchi O, Yamanashi Y, The muscle protein Dok-7 is essential for neuromuscular synaptogenesis. Science. 2006 Jun 23;312(5781):1802-5
1J:143441 Okamura Y, Saga Y, Notch signaling is required for the maintenance of enteric neural crest progenitors. Development. 2008 Nov;135(21):3555-65
7J:223933 Okubo T, Takada S, Pharyngeal arch deficiencies affect taste bud development in the circumvallate papilla with aberrant glossopharyngeal nerve formation. Dev Dyn. 2015 Jul;244(7):874-87
1J:213589 Ono K, Clavairoly A, Nomura T, Gotoh H, Uno A, Armant O, Takebayashi H, Zhang Q, Shimamura K, Itohara S, Parras CM, Ikenaka K, Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2. Development. 2014 May;141(10):2075-84
1J:106013 Ormestad M, Astorga J, Landgren H, Wang T, Johansson BR, Miura N, Carlsson P, Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production. Development. 2006 Mar;133(5):833-43
2*J:90276 Ota MS, Loebel DA, O'Rourke MP, Wong N, Tsoi B, Tam PP, Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells. Dev Dyn. 2004 Jun;230(2):216-28
2J:81765 Pabst O, Rummelies J, Winter B, Arnold HH, Targeted disruption of the homeobox gene Nkx2.9 reveals a role in development of the spinal accessory nerve. Development. 2003 Mar;130(6):1193-202
6J:99506 Pagliardini S, Ren J, Wevrick R, Greer JJ, Developmental abnormalities of neuronal structure and function in prenatal mice lacking the prader-willi syndrome gene necdin. Am J Pathol. 2005 Jul;167(1):175-91
3J:71196 Panchision DM, Pickel JM, Studer L, Lee SH, Turner PA, Hazel TG, McKay RD, Sequential actions of BMP receptors control neural precursor cell production and fate. Genes Dev. 2001 Aug 15;15(16):2094-110
1J:80423 Paratore C, Eichenberger C, Suter U, Sommer L, Sox10 haploinsufficiency affects maintenance of progenitor cells in a mouse model of Hirschsprung disease. Hum Mol Genet. 2002 Nov 15;11(24):3075-85
1*J:71878 Paratore C, Goerich DE, Suter U, Wegner M, Sommer L, Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling. Development. 2001 Oct;128(20):3949-61
1J:232516 Parchem RJ, Moore N, Fish JL, Parchem JG, Braga TT, Shenoy A, Oldham MC, Rubenstein JL, Schneider RA, Blelloch R, miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Rep. 2015 Aug 4;12(5):760-73
5J:92241 Parrish M, Ott T, Lance-Jones C, Schuetz G, Schwaeger-Nickolenko A, Monaghan AP, Loss of the Sall3 gene leads to palate deficiency, abnormalities in cranial nerves, and perinatal lethality. Mol Cell Biol. 2004 Aug;24(16):7102-12
1J:71547 Pasqualetti M, Neun R, Davenne M, Rijli FM, Retinoic acid rescues inner ear defects in Hoxa1 deficient mice. Nat Genet. 2001 Sep;29(1):34-9
5J:251979 Pasquini JM, Barrantes FJ, Quinta HR, Normal development of spinal axons in early embryo stages and posterior locomotor function is independent of GAL-1. J Comp Neurol. 2017 Sep 1;525(13):2861-2875
1J:44550 Pata I, Studer M, van Doorninck JH, Briscoe J, Kuuse S, Engel JD, Grosveld F, Karis A, The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4. Development. 1999 Dec;126(23):5523-31
1J:76188 Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A, A TRP channel that senses cold stimuli and menthol. Cell. 2002 Mar 8;108(5):705-15
3J:71188 Pernas-Alonso R, Perrone-Capano C, Volpicelli F, di Porzio U, Regionalized neurofilament accumulation and motoneuron degeneration are linked phenotypes in wobbler neuromuscular disease. Neurobiol Dis. 2001 Aug;8(4):581-9
5*J:33482 Pernas-Alonso R, Schaffner AE, Perrone-Capano C, Orlando A, Morelli F, Hansen CT, Barker JL, Esposito B, Cacucci F, di Porzio U, Early upregulation of medium neurofilament gene expression in developing spinal cord of the wobbler mouse mutant. Brain Res Mol Brain Res. 1996 Jun;38(2):267-75
3J:163856 Petrinovic MM, Duncan CS, Bourikas D, Weinman O, Montani L, Schroeter A, Maerki D, Sommer L, Stoeckli ET, Schwab ME, Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system. Development. 2010 Aug 1;137(15):2539-50
3J:111937 Petros TJ, Williams SE, Mason CA, Temporal regulation of EphA4 in astroglia during murine retinal and optic nerve development. Mol Cell Neurosci. 2006 May-Jun;32(1-2):49-66
1*J:31131 Pfaff SL, Mendelsohn M, Stewart CL, Edlund T, Jessell TM, Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. Cell. 1996 Jan 26;84(2):309-20
1*J:96667 Philips GT, Stair CN, Young Lee H, Wroblewski E, Berberoglu MA, Brown NL, Mastick GS, Precocious retinal neurons: Pax6 controls timing of differentiation and determination of cell type. Dev Biol. 2005 Mar 15;279(2):308-21
1*J:36236 Pinon LG, Minichiello L, Klein R, Davies AM, Timing of neuronal death in trkA, trkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling. Development. 1996 Oct;122(10):3255-61
2J:160165 Pinter R, Hindges R, Perturbations of microRNA function in mouse dicer mutants produce retinal defects and lead to aberrant axon pathfinding at the optic chiasm. PLoS One. 2010;5(4):e10021
1J:73904 Plump AS, Erskine L, Sabatier C, Brose K, Epstein CJ, Goodman CS, Mason CA, Tessier-Lavigne M, Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system. Neuron. 2002 Jan 17;33(2):219-32
1J:250766 Poliak S, Morales D, Croteau LP, Krawchuk D, Palmesino E, Morton S, Cloutier JF, Charron F, Dalva MB, Ackerman SL, Kao TJ, Kania A, Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons. Elife. 2015 Dec 3;4
1J:235719 Preitner N, Quan J, Li X, Nielsen FC, Flanagan JG, IMP2 axonal localization, RNA interactome, and function in the development of axon trajectories. Development. 2016 Aug 1;143(15):2753-9
1J:89367 Puelles E, Annino A, Tuorto F, Usiello A, Acampora D, Czerny T, Brodski C, Ang SL, Wurst W, Simeone A, Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain. Development. 2004 May;131(9):2037-48
3J:32994 Puliti A, Poirier V, Goossens M, Simonneau M, Neuronal defects in genotyped dominant megacolon (Dom) mouse embryos, a model for Hirschsprung disease. Neuroreport. 1996 Jan 31;7(2):489-92
3J:42259 Qiu Y, Pereira FA, DeMayo FJ, Lydon JP, Tsai SY, Tsai MJ, Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization. Genes Dev. 1997 Aug 1;11(15):1925-37
2J:212261 Qu Y, Huang Y, Feng J, Alvarez-Bolado G, Grove EA, Yang Y, Tissir F, Zhou L, Goffinet AM, Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent manner. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E2996-3004
5J:221584 Quesnel-Vallieres M, Irimia M, Cordes SP, Blencowe BJ, Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes Dev. 2015 Apr 1;29(7):746-59
5*J:266902 Rafipay A, Berg ALR, Erskine L, Vargesson N, Expression analysis of limb element markers during mouse embryonic development. Dev Dyn. 2018 Nov;247(11):1217-1226
1*J:89188 Raft S, Nowotschin S, Liao J, Morrow BE, Suppression of neural fate and control of inner ear morphogenesis by Tbx1. Development. 2004 Apr;131(8):1801-12
1*J:144192 Rajasekharan S, Baker KA, Horn KE, Jarjour AA, Antel JP, Kennedy TE, Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA. Development. 2009 Feb;136(3):415-26
1*J:22424 Rancourt DE, Tsuzuki T, Capecchi MR, Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation. Genes Dev. 1995 Jan 1;9(1):108-22
1J:101064 Ray A, Zoidl G, Weickert S, Wahle P, Dermietzel R, Site-specific and developmental expression of pannexin1 in the mouse nervous system. Eur J Neurosci. 2005 Jun;21(12):3277-90
3J:93814 Reddy T, Kablar B, Evidence for the involvement of neurotrophins in muscle transdifferentiation and acetylcholine receptor transformation in the esophagus of Myf5(-/-):MyoD(-/-) and NT-3(-/-) embryos. Dev Dyn. 2004 Dec;231(4):683-92
1J:209193 Redeker C, Schuster-Gossler K, Kremmer E, Gossler A, Normal development in mice over-expressing the intracellular domain of DLL1 argues against reverse signaling by DLL1 in vivo. PLoS One. 2013;8(10):e79050
1*J:157985 Reid BS, Sargent TD, Williams T, Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure. Dev Dyn. 2010 Feb 19;239(4):1188-1196
1J:93020 Remacle S, Abbas L, De Backer O, Pacico N, Gavalas A, Gofflot F, Picard JJ, Rezsohazy R, Loss of function but no gain of function caused by amino acid substitutions in the hexapeptide of Hoxa1 in vivo. Mol Cell Biol. 2004 Oct;24(19):8567-75
2J:186252 Riccomagno MM, Hurtado A, Wang H, Macopson JG, Griner EM, Betz A, Brose N, Kazanietz MG, Kolodkin AL, The RacGAP beta2-Chimaerin Selectively Mediates Axonal Pruning in the Hippocampus. Cell. 2012 Jun 22;149(7):1594-606
2J:43515 Riethmacher D, Sonnenberg-Riethmacher E, Brinkmann V, Yamaai T , Lewin GR , Birchmeier C, Severe neuropathies in mice with targeted mutations in the ErbB3 receptor. Nature. 1997 Oct 16;389(6652):725-30
1J:171272 Rinon A, Molchadsky A, Nathan E, Yovel G, Rotter V, Sarig R, Tzahor E, p53 coordinates cranial neural crest cell growth and epithelial-mesenchymal transition/delamination processes. Development. 2011 May;138(9):1827-38
3J:149456 Rocha SF, Lopes SS, Gossler A, Henrique D, Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity. Dev Biol. 2009 Apr 1;328(1):54-65
1*J:264207 Rodgers HM, Huffman VJ, Voronina VA, Lewandoski M, Mathers PH, The role of the Rx homeobox gene in retinal progenitor proliferation and cell fate specification. Mech Dev. 2018 Jun;151:18-29
1J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5
1*J:80765 Romand R, Hashino E, Dolle P, Vonesch JL, Chambon P, Ghyselinck NB, The retinoic acid receptors RARalpha and RARgamma are required for inner ear development. Mech Dev. 2002 Dec;119(2):213-23
1J:196582 Romand R, Krezel W, Beraneck M, Cammas L, Fraulob V, Messaddeq N, Kessler P, Hashino E, Dolle P, Retinoic acid deficiency impairs the vestibular function. J Neurosci. 2013 Mar 27;33(13):5856-66
1J:220958 Rosenthal EH, Tonchev AB, Stoykova A, Chowdhury K, Regulation of archicortical arealization by the transcription factor Zbtb20. Hippocampus. 2012 Nov;22(11):2144-56
3*J:235740 Rosin JM, Li W, Cox LL, Rolfe SM, Latorre V, Akiyama JA, Visel A, Kuramoto T, Bobola N, Turner EE, Cox TC, A distal 594 bp ECR specifies Hmx1 expression in pinna and lateral facial morphogenesis and is regulated by the Hox-Pbx-Meis complex. Development. 2016 Jul 15;143(14):2582-92
1J:251846 Ross JA, Webster RG, Lechertier T, Reynolds LE, Turmaine M, Bencze M, Jamshidi Y, Cetin H, Muntoni F, Beeson D, Hodilvala-Dilke K, Conti FJ, Multiple roles of integrin-alpha3 at the neuromuscular junction. J Cell Sci. 2017 May 15;130(10):1772-1784
1*J:41540 Rossel M, Capecchi MR, Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development. 1999 Nov;126(22):5027-40
1J:274433 Roy A, Francius C, Rousso DL, Seuntjens E, Debruyn J, Luxenhofer G, Huber AB, Huylebroeck D, Novitch BG, Clotman F, Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification. Development. 2012 Sep;139(17):3109-19
1J:146801 Ruggiu M, Herbst R, Kim N, Jevsek M, Fak JJ, Mann MA, Fischbach G, Burden SJ, Darnell RB, Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3513-8
2J:160735 Runker AE, Little GE, Suto F, Fujisawa H, Mitchell KJ, Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points. Neural Dev. 2008;3:34
1*J:31635 Saegusa H, Takahashi N, Noguchi S, Suemori H, Targeted disruption in the mouse Hoxc-4 locus results in axial skeleton homeosis and malformation of the xiphoid process. Dev Biol. 1996 Feb 25;174(1):55-64
1J:42014 Saga Y, Hata N, Koseki H, Taketo MM, Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 1997 Jul 15;11(14):1827-39
3J:84687 Sahay A, Molliver ME, Ginty DD, Kolodkin AL, Semaphorin 3F is critical for development of limbic system circuitry and is required in neurons for selective CNS axon guidance events. J Neurosci. 2003 Jul 30;23(17):6671-80
1J:149518 Sakagami K, Gan L, Yang XJ, Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina. J Neurosci. 2009 May 27;29(21):6932-44
2J:103506 Sakamaki K, Inoue T, Asano M, Sudo K, Kazama H, Sakagami J, Sakata S, Ozaki M, Nakamura S, Toyokuni S, Osumi N, Iwakura Y, Yonehara S, Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart. Cell Death Differ. 2002 Nov;9(11):1196-206
5J:246732 Saller MM, Huettl RE, Hanuschick P, Amend AL, Alberton P, Aszodi A, Huber AB, The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. J Cell Sci. 2016 Sep 01;129(17):3295-308
1J:223633 Sanchez-Calderon H, Rodriguez-de la Rosa L, Milo M, Pichel JG, Holley M, Varela-Nieto I, RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors. PLoS One. 2010;5(1):e8699
1J:231654 Sanchez-Ferras O, Bernas G, Farnos O, Toure AM, Souchkova O, Pilon N, A direct role for murine Cdx proteins in the trunk neural crest gene regulatory network. Development. 2016 Apr 15;143(8):1363-74
3J:171522 Sandell LL, Iulianella A, Melton KR, Lynn M, Walker M, Inman KE, Bhatt S, Leroux-Berger M, Crawford M, Jones NC, Dennis JF, Trainor PA, A phenotype-driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development. Genesis. 2011 Apr;49(4):342-59
1J:216471 Sapkota D, Chintala H, Wu F, Fliesler SJ, Hu Z, Mu X, Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4086-95
1J:106551 Satoh W, Gotoh T, Tsunematsu Y, Aizawa S, Shimono A, Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis. Development. 2006 Mar;133(6):989-99
1J:46856 Saucedo-Cardenas O, Quintana-Hau JD, Le WD, Smidt MP, Cox JJ , De Mayo F , Burbach JP , Conneely OM, Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):4013-8
1J:69138 Saxton TM, Cheng AM, Ong SH, Lu Y, Sakai R, Cross JC, Pawson T, Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis. Curr Biol. 2001 May 1;11(9):662-70
1J:70697 Scardigli R, Schuurmans C, Gradwohl G, Guillemot F, Crossregulation between Neurogenin2 and Pathways Specifying Neuronal Identity in the Spinal Cord. Neuron. 2001 Aug;31(2):203-17
1J:233532 Scekic-Zahirovic J, Sendscheid O, El Oussini H, Jambeau M, Sun Y, Mersmann S, Wagner M, Dieterle S, Sinniger J, Dirrig-Grosch S, Drenner K, Birling MC, Qiu J, Zhou Y, Li H, Fu XD, Rouaux C, Shelkovnikova T, Witting A, Ludolph AC, Kiefer F, Storkebaum E, Lagier-Tourenne C, Dupuis L, Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. EMBO J. 2016 May 17;35(10):1077-97
2J:168547 Schiff M, Rockle I, Burkhardt H, Weinhold B, Hildebrandt H, Thalamocortical pathfinding defects precede degeneration of the reticular thalamic nucleus in polysialic Acid-deficient mice. J Neurosci. 2011 Jan 26;31(4):1302-12
2J:156036 Schilling K, Oberdick J, The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Cerebellum. 2009 Dec;8(4):477-89
1J:215618 Schmidt ER, Brignani S, Adolfs Y, Lemstra S, Demmers J, Vidaki M, Donahoo AL, Lillevali K, Vasar E, Richards LJ, Karagogeos D, Kolk SM, Pasterkamp RJ, Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula. Neuron. 2014 Jul 16;83(2):372-87
1J:267448 Schmidt H, Dickey DM, Dumoulin A, Octave M, Robinson JW, Kuhn R, Feil R, Potter LR, Rathjen FG, Regulation of the Natriuretic Peptide Receptor 2 (Npr2) by Phosphorylation of Juxtamembrane Serine and Threonine Residues Is Essential for Bifurcation of Sensory Axons. J Neurosci. 2018 Nov 7;38(45):9768-9780
2*J:135081 Schmidt H, Stonkute A, Juttner R, Schaffer S, Buttgereit J, Feil R, Hofmann F, Rathjen FG, The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord. J Cell Biol. 2007 Oct 22;179(2):331-40
2J:39350 Schneider-Maunoury S, Seitanidou T, Charnay P, Lumsden A, Segmental and neuronal architecture of the hindbrain of Krox-20 mouse mutants. Development. 1997 Mar;124(6):1215-26
1*J:16077 Schneider-Maunoury S, Topilko P, Seitandou T, Levi G, Cohen-Tannoudji M, Pournin S, Babinet C, Charnay P, Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Cell. 1993 Dec 17;75(6):1199-214
1J:119934 Schoch S, Mittelstaedt T, Kaeser PS, Padgett D, Feldmann N, Chevaleyre V, Castillo PE, Hammer RE, Han W, Schmitz F, Lin W, Sudhof TC, Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. EMBO J. 2006 Dec 13;25(24):5852-63
1J:33032 Schorle H, Meier P, Buchert M, Jaenisch R, Mitchell PJ, Transcription factor AP-2 essential for cranial closure and craniofacial development. Nature. 1996 May 16;381(6579):235-8
1J:124679 Schreiner S, Cossais F, Fischer K, Scholz S, Bosl MR, Holtmann B, Sendtner M, Wegner M, Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages. Development. 2007 Sep;134(18):3271-81
1J:145608 Schuster-Gossler K, Harris B, Johnson KR, Serth J, Gossler A, Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development. BMC Dev Biol. 2009;9:6
2J:208432 Schwarz D, Varum S, Zemke M, Scholer A, Baggiolini A, Draganova K, Koseki H, Schubeler D, Sommer L, Ezh2 is required for neural crest-derived cartilage and bone formation. Development. 2014 Feb;141(4):867-77
1J:242073 Seberg HE, Van Otterloo E, Loftus SK, Liu H, Bonde G, Sompallae R, Gildea DE, Santana JF, Manak JR, Pavan WJ, Williams T, Cornell RA, TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF. PLoS Genet. 2017 Mar;13(3):e1006636
12J:264385 Sefton EM, Gallardo M, Kardon G, Developmental origin and morphogenesis of the diaphragm, an essential mammalian muscle. Dev Biol. 2018 Aug 15;440(2):64-73
2*J:37125 Serafini T, Colamarino SA, Leonardo ED, Wang H, Beddington R, Skarnes WC, Tessier-Lavigne M, Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell. 1996 Dec 13;87(6):1001-14
2J:248896 Shah B, Lutter D, Bochenek ML, Kato K, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Adams RH, Puschel AW, C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development. PLoS One. 2016;11(4):e0154174
2J:241040 Shah B, Lutter D, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Puschel AW, Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex. Cereb Cortex. 2017 Feb 01;27(2):1253-1269
1J:166758 Sheehy NT, Cordes KR, White MP, Ivey KN, Srivastava D, The neural crest-enriched microRNA miR-452 regulates epithelial-mesenchymal signaling in the first pharyngeal arch. Development. 2010 Dec;137(24):4307-16
1J:170414 Shekarabi M, Salin-Cantegrel A, Laganiere J, Gaudet R, Dion P, Rouleau GA, Cellular expression of the K+-Cl- cotransporter KCC3 in the central nervous system of mouse. Brain Res. 2011 Feb 16;1374:15-26
1J:166950 Shi M, Zheng MH, Liu ZR, Hu ZL, Huang Y, Chen JY, Zhao G, Han H, Ding YQ, DCC is specifically required for the survival of retinal ganglion and displaced amacrine cells in the developing mouse retina. Dev Biol. 2010 Dec 1;348(1):87-96
1J:131837 Shifley ET, Vanhorn KM, Perez-Balaguer A, Franklin JD, Weinstein M, Cole SE, Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton. Development. 2008 Mar;135(5):899-908
6*J:161753 Shimada N, Handa S, Uchida Y, Fukuda M, Maruyama N, Asaga H, Choi EK, Lee J, Ishigami A, Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain. J Neurosci Res. 2010 Mar;88(4):798-806
6*J:236098 Shin J, Salameh JS, Richter JD, Impaired neurodevelopment by the low complexity domain of CPEB4 reveals a convergent pathway with neurodegeneration. Sci Rep. 2016 Jul 06;6:29395
1J:228291 Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H, Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Nat Commun. 2015;6:10232
1J:119736 Shiota M, Heike T, Haruyama M, Baba S, Tsuchiya A, Fujino H, Kobayashi H, Kato T, Umeda K, Yoshimoto M, Nakahata T, Isolation and characterization of bone marrow-derived mesenchymal progenitor cells with myogenic and neuronal properties. Exp Cell Res. 2007 Mar 10;313(5):1008-23
1J:109116 Shirakabe K, Wakatsuki S, Kurisaki T, Fujisawa-Sehara A, Roles of Meltrin beta /ADAM19 in the processing of neuregulin. J Biol Chem. 2001 Mar 23;276(12):9352-8
3J:153515 Shu RZ, Zhang F, Liu XS, Li CL, Wang L, Tai YL, Wu XL, Yang X, Liao XD, Jin Y, Gu MM, Huang L, Pang XF, Wang ZG, Target deletion of the cytoskeleton-associated protein palladin does not impair neurite outgrowth in mice. PLoS One. 2009;4(9):e6916
1J:81202 Shu T, Butz KG, Plachez C, Gronostajski RM, Richards LJ, Abnormal development of forebrain midline glia and commissural projections in Nfia knock-out mice. J Neurosci. 2003 Jan 1;23(1):203-12
3*J:70492 Shu T, Shen WB, Richards LJ, Development of the perforating pathway: an ipsilaterally projecting pathway between the medial septum/diagonal band of Broca and the cingulate cortex that intersects the corpus callosum. J Comp Neurol. 2001 Aug 6;436(4):411-22
2J:166526 Shum AS, Tang LS, Copp AJ, Roelink H, Lack of motor neuron differentiation is an intrinsic property of the mouse secondary neural tube. Dev Dyn. 2010 Dec;239(12):3192-203
4J:176602 Simrick S, Lickert H, Basson MA, Sprouty genes are essential for the normal development of epibranchial ganglia in the mouse embryo. Dev Biol. 2011 Oct 1;358(1):147-55
1J:181058 Skidmore JM, Waite MR, Alvarez-Bolado G, Puelles L, Martin DM, A novel TaulacZ allele reveals a requirement for Pitx2 in formation of the mammillothalamic tract. Genesis. 2012 Jan;50(1):67-73
4J:97502 Snow HE, Riccio LM, Mjaatvedt CH, Hoffman S, Capehart AA, Versican expression during skeletal/joint morphogenesis and patterning of muscle and nerve in the embryonic mouse limb. Anat Rec A Discov Mol Cell Evol Biol. 2005 Feb;282(2):95-105
1*J:30246 Sommer L, Shah N, Rao M, Anderson DJ, The cellular function of MASH1 in autonomic neurogenesis. Neuron. 1995 Dec;15(6):1245-58
1J:119655 Song MR, Shirasaki R, Cai CL, Ruiz EC, Evans SM, Lee SK, Pfaff SL, T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration. Development. 2006 Dec;133(24):4945-55
1*J:73288 Sonnenberg-Riethmacher E, Miehe M, Stolt CC, Goerich DE, Wegner M, Riethmacher D, Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10. Mech Dev. 2001 Dec;109(2):253-65
1J:162396 Sottocornola R, Royer C, Vives V, Tordella L, Zhong S, Wang Y, Ratnayaka I, Shipman M, Cheung A, Gaston-Massuet C, Ferretti P, Molnar Z, Lu X, ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development. Dev Cell. 2010 Jul 20;19(1):126-37
2J:69868 Sporle R, Epaxial-adaxial-hypaxial regionalisation of the vertebrate somite: evidence for a somitic organiser and a mirror-image duplication. Dev Genes Evol. 2001 Apr;211(4):198-217
2*J:44060 Sporle R, Schughart K, System to identify individual somites and their derivatives in the developing mouse embryo. Dev Dyn. 1997 Nov;210(3):216-26
2J:204287 Stegeman S, Jolly LA, Premarathne S, Gecz J, Richards LJ, Mackay-Sim A, Wood SA, Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFbeta-mediated axonogenesis. PLoS One. 2013;8(7):e68287
1J:159839 Stevens HE, Smith KM, Maragnoli ME, Fagel D, Borok E, Shanabrough M, Horvath TL, Vaccarino FM, Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. J Neurosci. 2010 Apr 21;30(16):5590-602
2J:101317 Stewart L, Potok MA, Camper SA, Stifani S, Runx1 expression defines a subpopulation of displaced amacrine cells in the developing mouse retina. J Neurochem. 2005 Sep;94(6):1739-45
2J:169665 Stottmann RW, Klingensmith J, Bone morphogenetic protein signaling is required in the dorsal neural folds before neurulation for the induction of spinal neural crest cells and dorsal neurons. Dev Dyn. 2011 Apr;240(4):755-65
2J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23
3J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16
2J:73592 Suda Y, Matsuo I, Kuratani S, Aizawa S, Otx1 function overlaps with Otx2 in development of mouse forebrain and midbrain. Genes Cells. 1996 Nov;1(11):1031-44
1J:87446 Sundaresan V, Mambetisaeva E, Andrews W, Annan A, Knoll B, Tear G, Bannister L, Dynamic expression patterns of Robo (Robo1 and Robo2) in the developing murine central nervous system. J Comp Neurol. 2004 Jan 19;468(4):467-81
2J:98330 Suto F, Ito K, Uemura M, Shimizu M, Shinkawa Y, Sanbo M, Shinoda T, Tsuboi M, Takashima S, Yagi T, Fujisawa H, Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance. J Neurosci. 2005 Apr 6;25(14):3628-37
2*J:15577 Swiatek PJ, Gridley T, Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20. Genes Dev. 1993 Nov;7(11):2071-84
1J:17509 Swiatek PJ, Lindsell CE, del Amo FF, Weinmaster G, Gridley T, Notch1 is essential for postimplantation development in mice. Genes Dev. 1994 Mar 15;8(6):707-19
1J:44324 Szucsik JC, Witte DP, Li H, Pixley SK, Small KM, Potter SS, Altered forebrain and hindbrain development in mice mutant for the Gsh-2 homeobox gene. Dev Biol. 1997 Nov 15;191(2):230-42
1J:136315 Takahashi K, Ishida M, Hirokawa K, Takahashi H, Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus. Dev Dyn. 2008 Jun;237(6):1699-708
1*J:16409 Takakubo F, Dahl HH, Analysis of pyruvate dehydrogenase expression in embryonic mouse brain: localization and developmental regulation. Brain Res Dev Brain Res. 1994 Jan 14;77(1):63-76
1J:201612 Takeda S, Liu H, Sasagawa S, Dong Y, Trainor PA, Cheng EH, Hsieh JJ, HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma. J Clin Invest. 2013 Jul 1;123(7):3154-65
1J:126869 Tanaka M, Miyoshi J, Ishizaki H, Togawa A, Ohnishi K, Endo K, Matsubara K, Mizoguchi A, Nagano T, Sato M, Sasaki T, Takai Y, Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction. Mol Biol Cell. 2001 May;12(5):1421-30
3J:206855 Tanaka T, Wakabayashi T, Oizumi H, Nishio S, Sato T, Harada A, Fujii D, Matsuo Y, Hashimoto T, Iwatsubo T, CLAC-P/collagen type XXV is required for the intramuscular innervation of motoneurons during neuromuscular development. J Neurosci. 2014 Jan 22;34(4):1370-9
3J:43443 Taniguchi M, Yuasa S, Fujisawa H, Naruse I, Saga S, Mishina M, Yagi T, Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection. Neuron. 1997 Sep;19(3):519-30
1J:240973 Tao C, Zhang X, Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis. Cell Rep. 2016 Nov 08;17(7):1832-1844
4J:103924 Tarchini B, Huynh TH, Cox GA, Duboule D, HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside. Genes Dev. 2005 Dec 1;19(23):2862-76
1J:71900 Teng J, Takei Y, Harada A, Nakata T, Chen J, Hirokawa N, Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth, and microtubule organization. J Cell Biol. 2001 Oct 1;155(1):65-76
1J:134482 Teng L, Mundell NA, Frist AY, Wang Q, Labosky PA, Requirement for Foxd3 in the maintenance of neural crest progenitors. Development. 2008 May;135(9):1615-24
1*J:137167 Tennese AA, Gee CB, Wevrick R, Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons. Dev Dyn. 2008 Jul;237(7):1935-43
1J:205571 Ter-Avetisyan G, Rathjen FG, Schmidt H, Bifurcation of Axons from Cranial Sensory Neurons Is Disabled in the Absence of Npr2-Induced cGMP Signaling. J Neurosci. 2014 Jan 15;34(3):737-47
1*J:23161 Timsit S, Martinez S, Allinquant B, Peyron F, Puelles L, Zalc B, Oligodendrocytes originate in a restricted zone of the embryonic ventral neural tube defined by DM-20 mRNA expression. J Neurosci. 1995 Feb;15(2):1012-24
2J:98367 Tissir F, Bar I, Jossin Y, Goffinet AM, Protocadherin Celsr3 is crucial in axonal tract development. Nat Neurosci. 2005 Apr;8(4):451-7
1J:107718 Tiveron MC, Pattyn A, Hirsch MR, Brunet JF, Role of Phox2b and Mash1 in the generation of the vestibular efferent nucleus. Dev Biol. 2003 Aug 1;260(1):46-57
1*J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51
2J:65410 Tomita K, Moriyoshi K, Nakanishi S, Guillemot F, Kageyama R, Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system. EMBO J. 2000 Oct 16;19(20):5460-72
1J:229586 Tondeleir D, Noelanders R, Bakkali K, Ampe C, Beta-actin is required for proper mouse neural crest ontogeny. PLoS One. 2014;9(1):e85608
1*J:36834 Torres M, Gomez-Pardo E, Gruss P, Pax2 contributes to inner ear patterning and optic nerve trajectory. Development. 1996 Nov;122(11):3381-91
2*J:34768 Tremblay P, Pituello F, Gruss P, Inhibition of floor plate differentiation by Pax3: evidence from ectopic expression in transgenic mice. Development. 1996 Aug;122(8):2555-67
3*J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65
1J:134530 Tsunekawa N, Yanagawa Y, Obata K, Development of GABAergic neurons from the ventricular zone in the superior colliculus of the mouse. Neurosci Res. 2005 Mar;51(3):243-51
1*J:239297 Tymanskyj SR, Yang B, Falnikar A, Lepore AC, Ma L, MAP7 Regulates Axon Collateral Branch Development in Dorsal Root Ganglion Neurons. J Neurosci. 2017 Feb 08;37(6):1648-1661
1J:119939 Uehara M, Yashiro K, Mamiya S, Nishino J, Chambon P, Dolle P, Sakai Y, CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse. Dev Biol. 2007 Feb 15;302(2):399-411
10J:127418 Uemura M, Nakao S, Suzuki ST, Takeichi M, Hirano S, OL-Protocadherin is essential for growth of striatal axons and thalamocortical projections. Nat Neurosci. 2007 Sep;10(9):1151-9
4*J:111612 Uemura M, Takeichi M, alphaN-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. Dev Dyn. 2006 May 11;235(9):2559-2566
3J:109122 Uetani N, Chagnon MJ, Kennedy TE, Iwakura Y, Tremblay ML, Mammalian motoneuron axon targeting requires receptor protein tyrosine phosphatases sigma and delta. J Neurosci. 2006 May 31;26(22):5872-80
2J:182750 Usui N, Watanabe K, Ono K, Tomita K, Tamamaki N, Ikenaka K, Takebayashi H, Role of motoneuron-derived neurotrophin 3 in survival and axonal projection of sensory neurons during neural circuit formation. Development. 2012 Mar;139(6):1125-32
6J:268612 Vahedi-Hunter TA, Estep JA, Rosette KA, Rutlin ML, Wright KM, Riccomagno MM, Cas Adaptor Proteins Coordinate Sensory Axon Fasciculation. Sci Rep. 2018 Apr 16;8(1):5996
6J:240378 Van Battum EY, Gunput RA, Lemstra S, Groen EJ, Yu KL, Adolfs Y, Zhou Y, Hoogenraad CC, Yoshida Y, Schachner M, Akhmanova A, Pasterkamp RJ, The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections. Nat Commun. 2014 Jul 10;5:4317
3J:125106 Van de Putte T, Francis A, Nelles L, van Grunsven LA, Huylebroeck D, Neural crest-specific removal of Zfhx1b in mouse leads to a wide range of neurocristopathies reminiscent of Mowat-Wilson syndrome. Hum Mol Genet. 2007 Jun 15;16(12):1423-36
2*J:30217 Van Maele-Fabry G, Gofflot F, Clotman F, Picard JJ, Alterations of mouse embryonic branchial nerves and ganglia induced by ethanol. Neurotoxicol Teratol. 1995 Jul-Aug;17(4):497-506
1J:233609 Van Otterloo E, Feng W, Jones KL, Hynes NE, Clouthier DE, Niswander L, Williams T, MEMO1 drives cranial endochondral ossification and palatogenesis. Dev Biol. 2016 Jul 15;415(2):278-95
1J:270530 Van Otterloo E, Li H, Jones KL, Williams T, AP-2alpha and AP-2beta cooperatively orchestrate homeobox gene expression during branchial arch patterning. Development. 2018 Jan 25;145(2)
1J:90859 Verheijen MH, Chrast R, Burrola P, Lemke G, Local regulation of fat metabolism in peripheral nerves. Genes Dev. 2003 Oct 1;17(19):2450-64
1J:81969 Vermot J, Niederreither K, Garnier JM, Chambon P, Dolle P, Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1763-8
3J:170400 Vickerman L, Neufeld S, Cobb J, Shox2 function couples neural, muscular and skeletal development in the proximal forelimb. Dev Biol. 2011 Feb 15;350(2):323-36
1J:76173 Vitelli F, Morishima M, Taddei I, Lindsay EA, Baldini A, Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways. Hum Mol Genet. 2002 Apr 15;11(8):915-22
1J:155755 Voss AK, Collin C, Dixon MP, Thomas T, Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity. Dev Cell. 2009 Nov;17(5):674-86
2*J:67746 Wahba GM, Hostikka SL, Carpenter EM, The paralogous Hox genes Hoxa10 and Hoxd10 interact to pattern the mouse hindlimb peripheral nervous system and skeleton. Dev Biol. 2001 Mar 1;231(1):87-102
1J:203656 Waite MR, Skidmore JM, Micucci JA, Shiratori H, Hamada H, Martin JF, Martin DM, Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal development. Mol Cell Neurosci. 2013 Jan;52:128-39
1*J:127891 Wakefield L, Cornish V, Long H, Kawamura A, Zhang X, Hein DW, Sim E, Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system. Biomarkers. 2007 Sep 25;:1-13
1J:78736 Wang J, Mager J, Schnedier E, Magnuson T, The mouse PcG gene eed is required for Hox gene repression and extraembryonic development. Mamm Genome. 2002 Sep;13(9):493-503
1J:270995 Wang L, Tanaka Y, Wang D, Morikawa M, Zhou R, Homma N, Miyamoto Y, Hirokawa N, The Atypical Kinesin KIF26A Facilitates Termination of Nociceptive Responses by Sequestering Focal Adhesion Kinase. Cell Rep. 2018 Sep 11;24(11):2894-2907
1J:216499 Wang SH, Celic I, Choi SY, Riccomagno M, Wang Q, Sun LO, Mitchell SP, Vasioukhin V, Huganir RL, Kolodkin AL, Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization. J Neurosci. 2014 Sep 17;34(38):12745-61
1J:240021 Wang X, Astrof S, Neural crest cell-autonomous roles of fibronectin in cardiovascular development. Development. 2016 Jan 01;143(1):88-100
1J:235702 Wang Y, Wu Q, Yang P, Wang C, Liu J, Ding W, Liu W, Bai Y, Yang Y, Wang H, Gao S, Wang X, LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Nat Commun. 2016;7:10481
4J:104270 Wang Y, Zhang J, Mori S, Nathans J, Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling. J Neurosci. 2006 Jan 11;26(2):355-64
1J:238549 Warrier S, Nuwayhid S, Sabatino JA, Sugrue KF, Zohn IE, Supt20 is required for development of the axial skeleton. Dev Biol. 2017 Jan 15;421(2):245-257
1J:99648 Washington Smoak I, Byrd NA, Abu-Issa R, Goddeeris MM, Anderson R, Morris J, Yamamura K, Klingensmith J, Meyers EN, Sonic hedgehog is required for cardiac outflow tract and neural crest cell development. Dev Biol. 2005 Jul 15;283(2):357-72
4J:186829 Watanabe K, Tamamaki N, Furuta T, Ackerman SL, Ikenaka K, Ono K, Dorsally derived netrin 1 provides an inhibitory cue and elaborates the 'waiting period' for primary sensory axons in the developing spinal cord. Development. 2006 Apr;133(7):1379-87
3*J:73282 Watari N, Kameda Y, Takeichi M, Chisaka O, Hoxa3 regulates integration of glossopharyngeal nerve precursor cells. Dev Biol. 2001 Dec 1;240(1):15-31
1J:108519 Waters ST, Lewandoski M, A threshold requirement for Gbx2 levels in hindbrain development. Development. 2006 May;133(10):1991-2000
1J:119654 Weatherbee SD, Anderson KV, Niswander LA, LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction. Development. 2006 Dec;133(24):4993-5000
2J:181639 Wende H, Lechner SG, Cheret C, Bourane S, Kolanczyk ME, Pattyn A, Reuter K, Munier FL, Carroll P, Lewin GR, Birchmeier C, The transcription factor c-Maf controls touch receptor development and function. Science. 2012 Mar 16;335(6074):1373-6
1J:152855 Westenskow P, Piccolo S, Fuhrmann S, Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression. Development. 2009 Aug;136(15):2505-10
1J:121250 Whitlon DS, Rutishauser US, NCAM in the organ of Corti of the developing mouse. J Neurocytol. 1990 Dec;19(6):970-7
2J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45
1J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
3J:36870 Wilkinson GA, Farinas I, Backus C, Yoshida CK, Reichardt LF, Neurotrophin-3 is a survival factor in vivo for early mouse trigeminal neurons. J Neurosci. 1996 Dec 1;16(23):7661-9
2J:142500 Willaredt MA, Hasenpusch-Theil K, Gardner HA, Kitanovic I, Hirschfeld-Warneken VC, Gojak CP, Gorgas K, Bradford CL, Spatz J, Wolfl S, Theil T, Tucker KL, A crucial role for primary cilia in cortical morphogenesis. J Neurosci. 2008 Nov 26;28(48):12887-900
1*J:85573 Williams SE, Mann F, Erskine L, Sakurai T, Wei S, Rossi DJ, Gale NW, Holt CE, Mason CA, Henkemeyer M, Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm. Neuron. 2003 Sep 11;39(6):919-35
1J:116994 Winseck AK, Oppenheim RW, An in vivo analysis of Schwann cell programmed cell death in embryonic mice: the role of axons, glial growth factor, and the pro-apoptotic gene Bax. Eur J Neurosci. 2006 Oct;24(8):2105-17
3J:60159 Wolpowitz D, Mason TB, Dietrich P, Mendelsohn M, Talmage DA, Role LW, Cysteine-rich domain isoforms of the neuregulin-1 gene are required for maintenance of peripheral synapses. Neuron. 2000 Jan;25(1):79-91
2*J:227678 Woltering JM, Duboule D, Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model. Mech Dev. 2015 Nov;138 Pt 2:64-72
1J:194150 Wright KM, Lyon KA, Leung H, Leahy DJ, Ma L, Ginty DD, Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron. 2012 Dec 6;76(5):931-44
3J:200752 Wu F, Li R, Umino Y, Kaczynski TJ, Sapkota D, Li S, Xiang M, Fliesler SJ, Sherry DM, Gannon M, Solessio E, Mu X, Onecut1 is essential for horizontal cell genesis and retinal integrity. J Neurosci. 2013 Aug 7;33(32):13053-65, 13065a
2J:130489 Wu Y, Wang G, Scott SA, Capecchi MR, Hoxc10 and Hoxd10 regulate mouse columnar, divisional and motor pool identity of lumbar motoneurons. Development. 2008 Jan;135(1):171-82
1J:272890 Wu Z, Makihara S, Yam PT, Teo S, Renier N, Balekoglu N, Moreno-Bravo JA, Olsen O, Chedotal A, Charron F, Tessier-Lavigne M, Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells. Neuron. 2019 Feb 20;101(4):635-647.e4
2*J:19212 Wurst W, Auerbach AB, Joyner AL, Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development. 1994 Jul;120(7):2065-75
2J:35877 Xiang M, Gan L, Zhou L, Klein WH, Nathans J, Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11950-5
2J:91013 Xu H, Morishima M, Wylie JN, Schwartz RJ, Bruneau BG, Lindsay EA, Baldini A, Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract. Development. 2004 Jul;131(13):3217-27
1J:119950 Xu H, Viola A, Zhang Z, Gerken CP, Lindsay-Illingworth EA, Baldini A, Tbx1 regulates population, proliferation and cell fate determination of otic epithelial cells. Dev Biol. 2007 Feb 15;302(2):670-82
1J:211644 Xu K, Wu Z, Renier N, Antipenko A, Tzvetkova-Robev D, Xu Y, Minchenko M, Nardi-Dei V, Rajashankar KR, Himanen J, Tessier-Lavigne M, Nikolov DB, Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism. Science. 2014 Jun 13;344(6189):1275-9
1*J:45781 Xu W, Baribault H, Adamson ED, Vinculin knockout results in heart and brain defects during embryonic development. Development. 1998 Jan;125(2):327-37
1*J:39667 Yamada G, Ueno K, Nakamura S, Hanamure Y, Yasui K, Uemura M, Eizuru Y, Mansouri A, Blum M, Sugimura K, Nasal and pharyngeal abnormalities caused by the mouse goosecoid gene mutation. Biochem Biophys Res Commun. 1997 Apr 7;233(1):161-5
1J:88618 Yamanaka A, Hamano S, Miyazaki Y, Ishii K, Takeda A, Mak TW, Himeno K, Yoshimura A, Yoshida H, Hyperproduction of proinflammatory cytokines by WSX-1-deficient NKT cells in concanavalin A-induced hepatitis. J Immunol. 2004 Mar 15;172(6):3590-6
1J:228522 Yang SL, Yang M, Herrlinger S, Liang C, Lai F, Chen JF, MiR-302/367 regulate neural progenitor proliferation, differentiation timing, and survival in neurulation. Dev Biol. 2015 Dec 1;408(1):140-50
4J:69623 Yang X, Arber S, William C, Li L, Tanabe Y, Jessell TM, Birchmeier C, Burden SJ, Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron. 2001 May;30(2):399-410
1J:161412 Yang X, Kilgallen S, Andreeva V, Spicer DB, Pinz I, Friesel R, Conditional expression of Spry1 in neural crest causes craniofacial and cardiac defects. BMC Dev Biol. 2010;10:48
2*J:98440 Yaron A, Huang PH, Cheng HJ, Tessier-Lavigne M, Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins. Neuron. 2005 Feb 17;45(4):513-23
1J:149145 Ying G, Wu S, Hou R, Huang W, Capecchi MR, Wu Q, The protocadherin gene Celsr3 is required for interneuron migration in the mouse forebrain. Mol Cell Biol. 2009 Jun;29(11):3045-61
1*J:137506 Yoshikawa F, Sato Y, Tohyama K, Akagi T, Hashikawa T, Nagakura-Takagi Y, Sekine Y, Morita N, Baba H, Suzuki Y, Sugano S, Sato A, Furuichi T, Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane. J Biol Chem. 2008 Jul 25;283(30):20830-40
1*J:39344 Yoshikawa Y, Fujimori T, McMahon AP, Takada S, Evidence that absence of Wnt-3a signaling promotes neuralization instead of paraxial mesoderm development in the mouse. Dev Biol. 1997 Mar 15;183(2):234-42
4J:247207 Yoshitomi Y, Ikeda T, Saito H, Yoshitake Y, Ishigaki Y, Hatta T, Kato N, Yonekura H, JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin. J Cell Sci. 2017 Mar 01;130(5):916-926
1J:99496 Young HM, Turner KN, Bergner AJ, The location and phenotype of proliferating neural-crest-derived cells in the developing mouse gut. Cell Tissue Res. 2005 Apr;320(1):1-9
2J:49977 Yu BD, Hanson RD, Hess JL, Horning SE, Korsmeyer SJ, MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10632-6
1J:144429 Yumoto N, Wakatsuki S, Kurisaki T, Hara Y, Osumi N, Frisen J, Sehara-Fujisawa A, Meltrin beta/ADAM19 interacting with EphA4 in developing neural cells participates in formation of the neuromuscular junction. PLoS One. 2008;3(10):e3322
2J:226697 Yung AR, Nishitani AM, Goodrich LV, Phenotypic analysis of mice completely lacking netrin 1. Development. 2015 Nov 1;142(21):3686-91
1J:269471 Yzaguirre AD, Padmanabhan A, de Groh ED, Engleka KA, Li J, Speck NA, Epstein JA, Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos. Elife. 2015 Oct 13;4:e07780
1J:63729 Zeng Q, Kwan A, Oakley B, Gustatory innervation and bax-dependent caspase-2: participants in the life and death pathways of mouse taste receptor cells. J Comp Neurol. 2000 Sep 4;424(4):640-50
1*J:33031 Zhang J, Hagopian-Donaldson S, Serbedzija G, Elsemore J, Plehn-Dujowich D, McMahon AP, Flavell RA, Williams T, Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Nature. 1996 May 16;381(6579):238-41
1*J:20158 Zhang M, Kim HJ, Marshall H, Gendron-Maguire M, Lucas DA, Baron A, Gudas LJ, Gridley T, Krumlauf R, Grippo JF, Ectopic Hoxa-1 induces rhombomere transformation in mouse hindbrain. Development. 1994 Sep;120(9):2431-42
1J:241572 Zhang Q, Zagozewski J, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Brown NL, Wigle JT, Schuurmans C, Eisenstat DD, Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina. Development. 2017 May 01;144(9):1698-1711
1J:141138 Zhang Y, Burgess D, Overbeek PA, Govindarajan V, Dominant inhibition of lens placode formation in mice. Dev Biol. 2008 Nov 1;323(1):53-63
1J:143763 Zhang Y, Singh MK, Degenhardt KR, Lu MM, Bennett J, Yoshida Y, Epstein JA, Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Dev Biol. 2009 Jan 1;325(1):82-93
1J:112457 Zhang Z, Huynh T, Baldini A, Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development. Development. 2006 Sep;133(18):3587-95
1*J:85489 Zhong JL, Banerjee MD, Nikolic M, Pak1 and its T212 phosphorylated form accumulate in neurones and epithelial cells of the developing rodent. Dev Dyn. 2003 Sep;228(1):121-7
1J:62712 Zhong W, Jiang MM, Schonemann MD, Meneses JJ, Pedersen RA, Jan LY, Jan YN, Mouse numb is an essential gene involved in cortical neurogenesis. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6844-9
1J:109778 Zhou CJ, Pinson KI, Pleasure SJ, Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants. J Neurosci. 2004 Sep 1;24(35):7632-9
2J:134879 Zhou L, Bar I, Achouri Y, Campbell K, De Backer O, Hebert JM, Jones K, Kessaris N, de Rouvroit CL, O'Leary D, Richardson WD, Goffinet AM, Tissir F, Early forebrain wiring: genetic dissection using conditional Celsr3 mutant mice. Science. 2008 May 16;320(5878):946-9
2J:153073 Zhu X, Liu Y, Yin Y, Shao A, Zhang B, Kim S, Zhou J, MSC p43 required for axonal development in motor neurons. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15944-9
3J:68652 Zilian O, Saner C, Hagedorn L, Lee H, Sauberli E, Suter U, Sommer L, Aguet M, Multiple roles of mouse Numb in tuning developmental cell fates. Curr Biol. 2001 Apr 3;11(7):494-501
1J:190452 Zou C, Levine EM, Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding. PLoS Genet. 2012 Sep;8(9):e1002924
3J:94396 Zou D, Silvius D, Fritzsch B, Xu PX, Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes. Development. 2004 Nov;131(22):5561-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory