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Gene Expression Literature Summary
Symbol
Name
ID
Nf2
neurofibromatosis 2
MGI:97307

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2 E2.5 E3 E3.5 E5 E6 E6.5 E7 E7.5 E8 E8.5 E9 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E18 E18.5 A
In situ protein (section) 1 1 1 1 1 1 1 1 1 1 1 1 1
In situ RNA (section) 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1
In situ protein (whole mount) 1
In situ RNA (whole mount) 1 1 1
Western blot 1 1 1 2 2 2 2 2 2 1 2 2 2 1 1 1 3
RT-PCR 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2
cDNA clones 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nf2  neurofibromatosis 2   (Synonyms: merlin, moesin-ezrin-radixin-like protein, schwannomin)
Results  Reference
4*J:112453 Akhmametyeva EM, Mihaylova MM, Luo H, Kharzai S, Welling DB, Chang LS, Regulation of the Neurofibromatosis 2 gene promoter expression during embryonic development. Dev Dyn. 2006 Aug 7;235(10):2771-2785
3J:31660 Claudio JO, Lutchman M, Rouleau GA, Widespread but cell type-specific expression of the mouse neurofibromatosis type 2 gene. Neuroreport. 1995 Oct 2;6(14):1942-6
7J:199463 Cockburn K, Biechele S, Garner J, Rossant J, The hippo pathway member nf2 is required for inner cell mass specification. Curr Biol. 2013 Jul 8;23(13):1195-201
1J:166833 Gladden AB, Hebert AM, Schneeberger EE, McClatchey AI, The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell. 2010 Nov 16;19(5):727-39
15*J:96960 Gronholm M, Teesalu T, Tyynela J, Piltti K, Bohling T, Wartiovaara K, Vaheri A, Carpen O, Characterization of the NF2 protein merlin and the ERM protein ezrin in human, rat, and mouse central nervous system. Mol Cell Neurosci. 2005 Apr;28(4):683-93
11*J:19215 Huynh DP, Nechiporuk T, Pulst SM, Alternative transcripts in the mouse neurofibromatosis type 2 (NF2) gene are conserved and code for schwannomins with distinct C-terminal domains. Hum Mol Genet. 1994 Jul;3(7):1075-9
28J:37192 Huynh DP, Tran TM, Nechiporuk T, Pulst SM, Expression of neurofibromatosis 2 transcript and gene product during mouse fetal development. Cell Growth Differ. 1996 Nov;7(11):1551-61
3J:199301 Lavado A, He Y, Pare J, Neale G, Olson EN, Giovannini M, Cao X, Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
2J:40596 McClatchey AI, Saotome I, Ramesh V, Gusella JF, Jacks T, The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation. Genes Dev. 1997 May 15;11(10):1253-65
7J:125901 McLaughlin ME, Kruger GM, Slocum KL, Crowley D, Michaud NA, Huang J, Magendantz M, Jacks T, The Nf2 tumor suppressor regulates cell-cell adhesion during tissue fusion. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3261-6
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1J:162628 Zhang N, Bai H, David KK, Dong J, Zheng Y, Cai J, Giovannini M, Liu P, Anders RA, Pan D, The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Dev Cell. 2010 Jul 20;19(1):27-38

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory