Gene Expression Literature Summary

• Symbol: Casp2
• Name: caspase 2
• ID: MGI:97295

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E3.5	E4	E8	E10	E11	E11.5	E12	E13	E13.5	E14	E14.5	E15	E15.5	E16	E17	E17.5	E18	E	P
Immunohistochemistry (section)																						2
In situ RNA (section)									1			1										1
Northern blot						1	2	2		1	2		1		2		1	2		1		2
Western blot												1
RT-PCR	1	1	1	1	1		1			1		1		1	3	1	1		2	1		7
cDNA clones							1		1												1	2
RNase protection								1			1				1			1				2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Casp2  caspase 2   (Synonyms: Caspase-2, Ich-1, Nedd2)
Results	Reference
3*	J:54598 Araki T, Saruta T, Okano H, Miura M, Caspase activity is required for nephrogenesis in the developing mouse metanephros. Exp Cell Res. 1999 May 1;248(2):423-9
4*	J:56116 Exley GE, Tang C, McElhinny AS, Warner CM, Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos. Biol Reprod. 1999 Jul;61(1):231-9
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
2	J:344559 Hughes CHK, Smith OE, Meinsohn MC, Brunelle M, Gevry N, Murphy BD, Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2220849120
3	J:155983 Ikeda T, Kanazawa T, Otsuka S, Ichii O, Hashimoto Y, Kon Y, Expression of caspase family and muscle- and apoptosis-specific genes during skeletal myogenesis in mouse embryo. J Vet Med Sci. 2009 Sep;71(9):1161-8
1*	J:60591 Jablonka S, Schrank B, Kralewski M, Rossoll W, Sendtner M, Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: an animal model for spinal muscular atrophy type III. Hum Mol Genet. 2000 Feb 12;9(3):341-6
1	J:74158 Kuechle MK, Predd HM, Fleckman P, Dale BA, Presland RB, Caspase-14, a keratinocyte specific caspase: mRNA splice variants and expression pattern in embryonic and adult mouse. Cell Death Differ. 2001 Aug;8(8):868-70
4*	J:43230 Kumar S, Kinoshita M, Dorstyn L, Noda M, Origin, expression and possible functions of the two alternatively spliced forms of the mouse Nedd2 mRNA. Cell Death Differ. 1997 JUL;4(5):378-387
14	J:19453 Kumar S, Kinoshita M, Noda M, Copeland NG, Jenkins NA, Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme. Genes Dev. 1994 Jul 15;8(14):1613-26
7*	J:1344 Kumar S, Tomooka Y, Noda M, Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem Biophys Res Commun. 1992 Jun 30;185(3):1155-61
1	J:92421 Rajkovic A, Pangas SA, Ballow D, Suzumori N, Matzuk MM, NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. Science. 2004 Aug 20;305(5687):1157-9
1	J:96251 Ren J, Shi M, Liu R, Yang QH, Johnson T, Skarnes WC, Du C, The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):565-70
5*	J:59317 Roth KA, Kuan C, Haydar TF, D'Sa-Eipper C, Shindler KS, Zheng TS, Kuida K, Flavell RA, Rakic P, Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):466-71
1	J:71535 Simpson MT, MacLaurin JG, Xu D, Ferguson KL, Vanderluit JL, Davoli MA, Roy S, Nicholson DW, Robertson GS, Park DS, Slack RS, Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice. J Neurosci. 2001 Sep 15;21(18):7089-98
5*	J:20338 Wang L, Miura M, Bergeron L, Zhu H, Yuan J, Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell. 1994 Sep 9;78(5):739-50
1*	J:49788 Warner CM, Exley GE, McElhinny AS, Tang C, Genetic regulation of preimplantation mouse embryo survival. J Exp Zool. 1998 Sep-Oct 1;282(1-2):272-9
1	J:210623 Yeh ML, Gonda Y, Mommersteeg MT, Barber M, Ypsilanti AR, Hanashima C, Parnavelas JG, Andrews WD, Robo1 modulates proliferation and neurogenesis in the developing neocortex. J Neurosci. 2014 Apr 16;34(16):5717-31
1	J:63729 Zeng Q, Kwan A, Oakley B, Gustatory innervation and bax-dependent caspase-2: participants in the life and death pathways of mouse taste receptor cells. J Comp Neurol. 2000 Sep 4;424(4):640-50