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Symbol Name ID |
Lmnb1
lamin B1 MGI:96795 |
| Age | E0.5 | E7.5 | E8.5 | E9.5 | E10.5 | E12 | E12.5 | E13.5 | E14 | E14.5 | E15 | E16 | E17.5 | E18 | E18.5 | E | A |
| In situ protein (section) | 1 | 1 | 2 | 1 | 1 | 2 | 2 | 2 | |||||||||
| In situ RNA (section) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | ||||||||||
| In situ protein (whole mount) | 1 | ||||||||||||||||
| In situ RNA (whole mount) | 2 | 2 | 1 | ||||||||||||||
| In situ reporter (knock in) | 1 | ||||||||||||||||
| Western blot | 1 | 2 | 1 | 1 | 2 | ||||||||||||
| RT-PCR | 1 | 1 | 1 | 1 | 1 |
| Lmnb1 lamin B1 | |
| Results | Reference |
| 3 | J:180603 Bertrand AT, Renou L, Papadopoulos A, Beuvin M, Lacene E, Massart C, Ottolenghi C, Decostre V, Maron S, Schlossarek S, Cattin ME, Carrier L, Malissen M, Arimura T, Bonne G, DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death. Hum Mol Genet. 2012 Mar 1;21(5):1037-48 |
| 5* | J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247 |
| 1 | J:83658 Burns KH, Viveiros MM, Ren Y, Wang P, DeMayo FJ, Frail DE, Eppig JJ, Matzuk MM, Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos. Science. 2003 Apr 25;300(5619):633-6 |
| 1 | J:82346 Ceni C, Pochon N, Brun V, Muller-Steffner H, Andrieux A, Grunwald D, Schuber F, De Waard M, Lund F, Villaz M, Moutin MJ, CD38-dependent ADP-ribosyl cyclase activity in developing and adult mouse brain. Biochem J. 2003 Feb 15;370(Pt 1):175-83 |
| 4 | J:144707 Chiu SY, Asai N, Costantini F, Hsu W, SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages. PLoS Biol. 2008 Dec 16;6(12):e310 |
| 1 | J:158610 Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG, Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5076-81 |
| 4 | J:194083 De Castro SC, Malhas A, Leung KY, Gustavsson P, Vaux DJ, Copp AJ, Greene ND, Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice. PLoS Genet. 2012;8(11):e1003059 |
| 1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
| 1 | J:190019 Feldhahn N, Ferretti E, Robbiani DF, Callen E, Deroubaix S, Selleri L, Nussenzweig A, Nussenzweig MC, The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo. EMBO J. 2012 Oct 17;31(20):4045-56 |
| 1 | J:130649 Fossat N, Le Greneur C, Beby F, Vincent S, Godement P, Chatelain G, Lamonerie T, A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors. BMC Dev Biol. 2007;7:122 |
| 3* | J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998; |
| 3 | J:152865 Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH, Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol. 2009 Aug 15;332(2):273-86 |
| 1* | J:107596 Goodchild RE, Kim CE, Dauer WT, Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope. Neuron. 2005 Dec 22;48(6):923-32 |
| 2* | J:171409 GUDMAP: the GenitoUrinary Development Molecular Anatomy Project, http://www.gudmap.org. 2004; |
| 1 | J:117378 Hosoya-Ohmura S, Mochizuki N, Suzuki M, Ohneda O, Ohneda K, Yamamoto M, GATA-4 incompletely substitutes for GATA-1 in promoting both primitive and definitive erythropoiesis in vivo. J Biol Chem. 2006 Oct 27;281(43):32820-30 |
| 1 | J:160544 Kim CE, Perez A, Perkins G, Ellisman MH, Dauer WT, A molecular mechanism underlying the neural-specific defect in torsinA mutant mice. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9861-6 |
| 1 | J:178993 Kim Y, Sharov AA, McDole K, Cheng M, Hao H, Fan CM, Gaiano N, Ko MS, Zheng Y, Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells. Science. 2011 Dec 23;334(6063):1706-10 |
| 1 | J:143917 Tsika RW, Schramm C, Simmer G, Fitzsimons DP, Moss RL, Ji J, Overexpression of TEAD-1 in Transgenic Mouse Striated Muscles Produces a Slower Skeletal Muscle Contractile Phenotype. J Biol Chem. 2008 Dec 26;283(52):36154-67 |
| 2* | J:91473 Vergnes L, Peterfy M, Bergo MO, Young SG, Reue K, Lamin B1 is required for mouse development and nuclear integrity. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10428-33 |
| 1 | J:155113 Zhang X, Lei K, Yuan X, Wu X, Zhuang Y, Xu T, Xu R, Han M, SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron. 2009 Oct 29;64(2):173-87 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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