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Gene Expression Literature Summary
Symbol
Name
ID
Itga2
integrin alpha 2
MGI:96600

27 matching records from 27 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E3.5 E4 E6.5 E7.5 E8.5 E9.5 E10.5 E11.5 E12.5 E13 E13.5 E14.5 E15 E15.5 E16 E16.5 E17.5 E18.5 E P
Immunohistochemistry (section) 1 1 2 2 2 2 3 1 3 8 2 3 3 4 2 1 6
In situ RNA (section) 1 1 1 1 1 1 3 1 5 1 1 1 2 2 1 2
In situ reporter (knock in) 1
RT-PCR 1 1 1 1 2 1 1 4
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Itga2  integrin alpha 2   (Synonyms: CD49B, DX5, VLA-2 receptor, alpha 2 subunit)
Results  Reference
1J:112701 Bailey PJ, Klos JM, Andersson E, Karlen M, Kallstrom M, Ponjavic J, Muhr J, Lenhard B, Sandelin A, Ericson J, A global genomic transcriptional code associated with CNS-expressed genes. Exp Cell Res. 2006 Oct 1;312(16):3108-19
4J:94436 Barbour W, Saika S, Miyamoto T, Ohkawa K, Utsunomiya H, Ohnishi Y, Expression patterns of beta1-related alpha integrin subunits in murine lens during embryonic development and wound healing. Curr Eye Res. 2004 Jul;29(1):1-10
1J:152968 Bazigou E, Xie S, Chen C, Weston A, Miura N, Sorokin L, Adams R, Muro AF, Sheppard D, Makinen T, Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Dev Cell. 2009 Aug;17(2):175-86
3*J:51702 Carroll JM, Luetteke NC, Lee DC, Watt FM, Role of integrins in mouse eyelid development: studies in normal embryos and embryos in which there is a failure of eyelid fusion. Mech Dev. 1998 Nov;78(1-2):37-45
2J:195350 Chaen T, Konno T, Egashira M, Bai R, Nomura N, Nomura S, Hirota Y, Sakurai T, Imakawa K, Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence. PLoS One. 2012;7(11):e48933
1J:84858 Chan CS, Weeber EJ, Kurup S, Sweatt JD, Davis RL, Integrin requirement for hippocampal synaptic plasticity and spatial memory. J Neurosci. 2003 Aug 6;23(18):7107-16
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
2*J:32930 Gardner H, Kreidberg J, Koteliansky V, Jaenisch R, Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion. Dev Biol. 1996 May 1;175(2):301-13
1J:251433 Ha T, Moon KH, Dai L, Hatakeyama J, Yoon K, Park HS, Kong YY, Shimamura K, Kim JW, The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina. Cell Rep. 2017 Apr 11;19(2):351-363
1*J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1*J:61486 Littlewood Evans A, Muller U, Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1. Nat Genet. 2000 Apr;24(4):424-8
1J:217538 Lui JH, Nowakowski TJ, Pollen AA, Javaherian A, Kriegstein AR, Oldham MC, Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex. Nature. 2014 Nov 13;515(7526):264-8
1J:137063 Nikolova-Krstevski V, Bhasin M, Otu HH, Libermann T, Oettgen P, Gene expression analysis of embryonic stem cells expressing VE-cadherin (CD144) during endothelial differentiation. BMC Genomics. 2008;9:240
5J:44398 Ohyama K, Kawano H, Kawamura K, Localization of extracellular matrix molecules, integrins and their regulators, TGF betas, is correlated with axon pathfinding in the spinal cord of normal and Danforth's short tail mice. Brain Res Dev Brain Res. 1997 Nov 12;103(2):143-54
2J:92200 Popova SN, Rodriguez-Sanchez B, Liden A, Betsholtz C, Van Den Bos T, Gullberg D, The mesenchymal alpha11beta1 integrin attenuates PDGF-BB-stimulated chemotaxis of embryonic fibroblasts on collagens. Dev Biol. 2004 Jun 15;270(2):427-42
2J:84372 Previtali SC, Nodari A, Taveggia C, Pardini C, Dina G, Villa A, Wrabetz L, Quattrini A, Feltri ML, Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles. J Neurosci. 2003 Jul 2;23(13):5520-30
1J:203162 Ray A, Treloar HB, IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses. Mol Cell Neurosci. 2012 Jul;50(3-4):238-49
5J:94926 Shiojiri N, Sugiyama Y, Immunolocalization of extracellular matrix components and integrins during mouse liver development. Hepatology. 2004 Aug;40(2):346-55
1J:53320 Stepp MA, Alpha9 and beta8 integrin expression correlates with the merger of the developing mouse eyelids. Dev Dyn. 1999 Mar;214(3):216-28
1*J:16243 Sutherland AE, Calarco PG, Damsky CH, Developmental regulation of integrin expression at the time of implantation in the mouse embryo. Development. 1993 Dec;119(4):1175-86
1J:229358 Teo ZL, McQueen-Miscamble L, Turner K, Martinez G, Madakashira B, Dedhar S, Robinson ML, de Iongh RU, Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation. Exp Eye Res. 2014 Apr;121:130-42
1J:70388 Weinstein M, Monga SP, Liu Y, Brodie SG, Tang Y, Li C, Mishra L, Deng CX, Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development. Mol Cell Biol. 2001 Aug;21(15):5122-31
5J:275806 Wu D, Schieren I, Qian Y, Zhang C, Jessell TM, de Nooij JC, A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype. J Neurosci. 2019 May 29;39(22):4252-4267
31*J:17839 Wu JE, Santoro SA, Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development. Dev Dyn. 1994 Apr;199(4):292-314
5*J:33225 Wu JE, Santoro SA, Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn. 1996 Jun;206(2):169-81
2*J:60228 Yuan B, Li C, Kimura S, Engelhardt RT, Smith BR, Minoo P, Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos. Dev Dyn. 2000 Feb;217(2):180-90

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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory