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Gene Expression Literature Summary
Symbol
Name
ID
Insr
insulin receptor
MGI:96575

24 matching records from 24 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2 E2.5 E3.5 E4 E4.5 E7.5 E8 E8.5 E9.5 E10.5 E11.5 E12.5 E13.5 E14 E14.5 E15.5 E17.5 E18 E18.5 E A
In situ RNA (section) 1 1 2 1
Western blot 1 1 3 3
RT-PCR 2 2 1 2 2 1 1 1 2 3 3 5 4 4 2 5 1 3 2 8
cDNA clones 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Insr  insulin receptor   (Synonyms: 4932439J01Rik, CD220, D630014A15Rik, IR, IR-A, IR-B)
Results  Reference
1J:130984 Bera TK, Liu XF, Yamada M, Gavrilova O, Mezey E, Tessarollo L, Anver M, Hahn Y, Lee B, Pastan I, A model for obesity and gigantism due to disruption of the Ankrd26 gene. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):270-5
1J:203449 Berry DC, Jacobs H, Marwarha G, Gely-Pernot A, O'Byrne SM, DeSantis D, Klopfenstein M, Feret B, Dennefeld C, Blaner WS, Croniger CM, Mark M, Noy N, Ghyselinck NB, The STRA6 receptor is essential for retinol-binding protein-induced insulin resistance but not for maintaining vitamin A homeostasis in tissues other than the eye. J Biol Chem. 2013 Aug 23;288(34):24528-39
2J:184234 Chirivella L, Cano-Jaimez M, Perez-Sanchez F, Herraez L, Carretero J, Farinas I, Burks DJ, Kirstein M, IRS2 signalling is required for the development of a subset of sensory spinal neurons. Eur J Neurosci. 2012 Feb;35(3):341-52
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:106827 Duvillie B, Currie C, Chrones T, Bucchini D, Jami J, Joshi RL, Hill DJ, Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin. Endocrinology. 2002 Apr;143(4):1530-7
2J:175639 Erickson RP, Strnatka D, Insulin receptor-related (Irr) is expressed in pre-implantation embryos: A possible relationship to 'growth factor Y' and sex determination. Mol Reprod Dev. 2011 Aug;78(8):552
2J:19199 Larsson-Blomberg L, Dzierzak E, Isolation of tyrosine kinase related genes expressed in the early hematopoietic system. FEBS Lett. 1994 Jul 11;348(2):119-25
10J:171220 Li P, Cavallero S, Gu Y, Chen TH, Hughes J, Hassan AB, Bruning JC, Pashmforoush M, Sucov HM, IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development. Development. 2011 May;138(9):1795-805
4*J:158405 Liang L, Guo WH, Esquiliano DR, Asai M, Rodriguez S, Giraud J, Kushner JA, White MF, Lopez MF, Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis. Endocrinology. 2010 Feb;151(2):741-7
2J:192831 Lin JC, Yan YT, Hsieh WK, Peng PJ, Su CH, Tarn WY, RBM4 promotes pancreas cell differentiation and insulin expression. Mol Cell Biol. 2013 Jan;33(2):319-27
8J:199085 Martinez-Campos E, Hernandez-Sanmiguel E, Lopez-Sanchez C, De Pablo F, Hernandez-Sanchez C, Alternative splicing variants of proinsulin mRNA and the effects of excess proinsulin on cardiac morphogenesis. FEBS Lett. 2013 Jul 11;587(14):2272-7
1J:203690 Martinez-Lopez N, Athonvarangkul D, Sahu S, Coletto L, Zong H, Bastie CC, Pessin JE, Schwartz GJ, Singh R, Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development. EMBO Rep. 2013 Sep;14(9):795-803
1J:154998 Mascarenhas MI, Parker A, Dzierzak E, Ottersbach K, Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling. Blood. 2009 Nov 19;114(21):4645-53
4J:86618 Nef S, Verma-Kurvari S, Merenmies J, Vassalli JD, Efstratiadis A, Accili D, Parada LF, Testis determination requires insulin receptor family function in mice. Nature. 2003 Nov 20;426(6964):291-5
1J:123298 Nguyen TT, Sheppard AM, Kaye PL, Noakes PG, IGF-I and insulin activate mitogen-activated protein kinase via the type 1 IGF receptor in mouse embryonic stem cells. Reproduction. 2007 Jul;134(1):41-9
3J:174705 Novitskaya T, Baserga M, de Caestecker MP, Organ-specific defects in insulin-like growth factor and insulin receptor signaling in late gestational asymmetric intrauterine growth restriction in Cited1 mutant mice. Endocrinology. 2011 Jun;152(6):2503-16
2J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160
4*J:35225 Rappolee DA, Sturm KS, Behrendtsen O, Schultz GA, Pedersen RA, Werb Z, Insulin-like growth factor II acts through an endogenous growth pathway regulated by imprinting in early mouse embryos. Genes Dev. 1992 Jun;6(6):939-52
6J:67067 Stojanov T, O'Neill C, In vitro fertilization causes epigenetic modifications to the onset of gene expression from the zygotic genome in mice. Biol Reprod. 2001 Feb;64(2):696-705
5*J:10840 Telford NA, Hogan A, Franz CR, Schultz GA, Expression of genes for insulin and insulin-like growth factors and receptors in early postimplantation mouse embryos and embryonal carcinoma cells. Mol Reprod Dev. 1990 Oct;27(2):81-92
1J:138822 Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR, New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature. 2008 Aug 21;454(7207):1000-4
3J:91730 Verma-Kurvari S, Parada LF, Identification of tyrosine kinases expressed in the male mouse gubernaculum during development. Dev Dyn. 2004 Aug;230(4):660-5
3J:121631 Xie L, Chen H, Overbeek PA, Reneker LW, Elevated insulin signaling disrupts the growth and differentiation pattern of the mouse lens. Mol Vis. 2007;13:397-407
1J:102264 Yamashita H, Shao J, Qiao L, Pagliassotti M, Friedman JE, Effect of spontaneous gestational diabetes on fetal and postnatal hepatic insulin resistance in Lepr(db/+) mice. Pediatr Res. 2003 Mar;53(3):411-8

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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory