Gene Expression Literature Summary

• Symbol: Grn
• Name: granulin
• ID: MGI:95832

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E3.5	E4	E6.5	E7.5	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16	E16.5	E17.5	P
Immunohistochemistry (section)							1			1	1	1	1	1	1	1			1	4
In situ RNA (section)								1	1	1	1	1		1	1	1	1	1
Immunohistochemistry (whole mount)	1	1	1	1	1	1														1
In situ RNA (whole mount)					1					1		1			1
In situ reporter (knock in)																1				1
Western blot															1				1	3
RT-PCR	1	1		1	1	1														2
cDNA clones												1						1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Grn  granulin   (Synonyms: acrogranulin, epithelin, PC cell-derived growth factor, Pgrn, progranulin)
Results	Reference
7*	J:84942 Daniel R, Daniels E, He Z, Bateman A, Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development. Dev Dyn. 2003 Aug;227(4):593-9
11*	J:59921 Diaz-Cueto L, Stein P, Jacobs A, Schultz RM, Gerton GL, Modulation of mouse preimplantation embryo development by acrogranin (epithelin/granulin precursor). Dev Biol. 2000 Jan 15;217(2):406-18
1	J:239480 Kong L, Zhao YP, Tian QY, Feng JQ, Kobayashi T, Merregaert J, Liu CJ, Extracellular matrix protein 1, a direct targeting molecule of parathyroid hormone-related peptide, negatively regulates chondrogenesis and endochondral ossification via associating with progranulin growth factor. FASEB J. 2016 Aug;30(8):2741-54
6*	J:167031 Petkau TL, Neal SJ, Orban PC, MacDonald JL, Hill AM, Lu G, Feldman HH, Mackenzie IR, Leavitt BR, Progranulin expression in the developing and adult murine brain. J Comp Neurol. 2010 Oct 1;518(19):3931-47
3	J:100669 Qin J, Diaz-Cueto L, Schwarze JE, Takahashi Y, Imai M, Isuzugawa K, Yamamoto S, Chang KT, Gerton GL, Imakawa K, Effects of progranulin on blastocyst hatching and subsequent adhesion and outgrowth in the mouse. Biol Reprod. 2005 Sep;73(3):434-42
10	J:342618 Thomasen PB, Salasova A, Kjaer-Sorensen K, Woloszczukova L, Lavicky J, Login H, Tranberg-Jensen J, Almeida S, Beel S, Kavkova M, Qvist P, Kjolby M, Ovesen PL, Nolte S, Vestergaard B, Udrea AC, Nejsum LN, Chao MV, Van Damme P, Krivanek J, Dasen J, Oxvig C, Nykjaer A, SorCS2 binds progranulin to regulate motor neuron development. Cell Rep. 2023 Oct 26;42(11):113333
1	J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21;
4*	J:65653 Wertz K, Herrmann BG, Large-scale screen for genes involved in gonad development. Mech Dev. 2000 Nov;98(1-2):51-70
7	J:305738 Xu B, Chen X, Ding Y, Chen C, Liu T, Zhang H, Abnormal angiogenesis of placenta in progranulindeficient mice. Mol Med Rep. 2020 Oct;22(4):3482-3492