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Gene Expression Literature Summary
Symbol
Name
ID
Nr3c1
nuclear receptor subfamily 3, group C, member 1
MGI:95824

50 matching records from 50 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1.5 E2 E2.5 E3 E3.5 E4.5 E9 E9.5 E10.5 E11 E11.5 E12.5 E13 E13.5 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19 E19.5 E A
In situ protein (section) 1 4 3 6 1 7 1 4 5 1 4 1 3
In situ RNA (section) 1 2 3 4 4 6 3 2 3 6
In situ protein (whole mount) 1
In situ RNA (whole mount) 2 1 1 1
In situ reporter (knock in) 1 1 1 1 1 1
Northern blot 1 2 2 1 1 3
Western blot 2 3 3 2 3 5 4
RT-PCR 1 1 1 1 1 1 1 1 1 1 1 2 2 5 2 2 1 3 1 3 1 10 1 1 8
cDNA clones 1
RNase protection 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nr3c1  nuclear receptor subfamily 3, group C, member 1   (Synonyms: glucocorticoid receptor, GR, Grl1, Grl-1)
Results  Reference
10J:19026 Abbott BD, McNabb FM, Lau C, Glucocorticoid receptor expression during the development of the embryonic mouse secondary palate. J Craniofac Genet Dev Biol. 1994 Apr-Jun;14(2):87-96
4*J:55992 Abbott BD, Schmid JE, Brown JG, Wood CR, White RD, Buckalew AR, Held GA, RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone. Toxicol Sci. 1999 Jan;47(1):76-85
1J:141601 Bayo P, Sanchis A, Bravo A, Cascallana JL, Buder K, Tuckermann J, Schutz G, Perez P, Glucocorticoid receptor is required for skin barrier competence. Endocrinology. 2008 Mar;149(3):1377-88
2J:82890 Cascallana JL, Bravo A, Page A, Budunova I, Slaga TJ, Jorcano JL, Perez P, Disruption of eyelid and cornea development by targeted overexpression of the glucocorticoid receptor. Int J Dev Biol. 2003 Feb;47(1):59-64
4J:119560 Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA, A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development. 2006 Oct;133(20):4119-29
2*J:168654 Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL, Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92
2J:27441 Cole TJ, Blendy JA, Monaghan AP, Krieglstein K, Schmid W, Aguzzi A, Fantuzzi G, Hummler E, Unsicker K, Schutz G, Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev. 1995 Jul 1;9(13):1608-21
1*J:57509 Cole TJ, Harris HJ, Hoong I, Solomon N, Smith R, Krozowski Z, Fullerton MJ, The glucocorticoid receptor is essential for maintaining basal and dexamethasone-induced repression of the murine corticosteroid-binding globulin gene. Mol Cell Endocrinol. 1999 Aug 20;154(1-2):29-36
3J:192943 Cuffe JS, O'Sullivan L, Simmons DG, Anderson ST, Moritz KM, Maternal corticosterone exposure in the mouse has sex-specific effects on placental growth and mRNA expression. Endocrinology. 2012 Nov;153(11):5500-11
7J:36524 Erichsen S, Bagger-Sjoback D, Curtis L, Zuo J, Rarey K, Hultcrantz M, Appearance of glucocorticoid receptors in the inner ear of the mouse during development. Acta Otolaryngol (Stockh). 1996 Sep;116(5):721-5
2J:39131 Fujii S, Hojo H, Kaneda M, Teramoto S, Immunohistochemical evaluation of glucocorticoid receptors in developing eyelids of Nc-eob fetuses with genetically determined open-eyelid malformation. Cong Anom. 1996;36:227-34
4J:80697 Gartner H, Graul MC, Oesterreicher TJ, Finegold MJ, Henning SJ, Development of the fetal intestine in mice lacking the glucocorticoid receptor (GR). J Cell Physiol. 2003 Jan;194(1):80-7
1J:147261 Gesina E, Blondeau B, Milet A, Le Nin I, Duchene B, Czernichow P, Scharfmann R, Tronche F, Breant B, Glucocorticoid signalling affects pancreatic development through both direct and indirect effects. Diabetologia. 2006 Dec;49(12):2939-47
3*J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
3*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
7*J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
1J:131988 Han D, Jeon S, Sohn DH, Lee C, Ahn S, Kim WK, Chung H, Seong RH, SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development. Dev Biol. 2008 Mar 1;315(1):136-46
1J:191801 Huang CC, Shih MC, Hsu NC, Chien Y, Chung BC, Fetal glucocorticoid synthesis is required for development of fetal adrenal medulla and hypothalamus feedback suppression. Endocrinology. 2012 Oct;153(10):4749-56
6*J:26693 Jaskoll T, Choy HA, Chen H, Melnick M, The CORT-GR signal transduction pathway and CORT-induced cleft palate in H-2 congenic mice. J Craniofac Genet Dev Biol. 1995 Apr-Jun;15(2):57-65
5J:22585 Jaskoll T, Choy HA, Melnick M, Glucocorticoids, TGF-beta, and embryonic mouse salivary gland morphogenesis. J Craniofac Genet Dev Biol. 1994 Oct-Dec;14(4):217-30
7J:33469 Jaskoll T, Choy HA, Melnick M, The glucocorticoid-glucocorticoid receptor signal transduction pathway, transforming growth factor-beta, and embryonic mouse lung development in vivo. Pediatr Res. 1996 May;39(5):749-59
3J:95006 Kalinichenko VV, Gusarova GA, Kim IM, Shin B, Yoder HM, Clark J, Sapozhnikov AM, Whitsett JA, Costa RH, Foxf1 haploinsufficiency reduces Notch-2 signaling during mouse lung development. Am J Physiol Lung Cell Mol Physiol. 2004 Mar;286(3):L521-30
2J:169234 Kim JD, Kim H, Ekram MB, Yu S, Faulk C, Kim J, Rex1/Zfp42 as an epigenetic regulator for genomic imprinting. Hum Mol Genet. 2011 Apr 1;20(7):1353-62
6J:28514 Lau EC, Li ZQ, Santos V, Slavkin HC, Messenger RNA phenotyping for semi-quantitative comparison of glucocorticoid receptor transcript levels in the developing embryonic mouse palate. J Steroid Biochem Mol Biol. 1993 Dec;46(6):751-8
3J:200617 Li A, Hardy R, Stoner S, Tuckermann J, Seibel M, Zhou H, Deletion of mesenchymal glucocorticoid receptor attenuates embryonic lung development and abdominal wall closure. PLoS One. 2013;8(5):e63578
1*J:122356 Lovgren AK, Kovarova M, Koller BH, cPGES/p23 is required for glucocorticoid receptor function and embryonic growth but not prostaglandin E2 synthesis. Mol Cell Biol. 2007 Jun;27(12):4416-30
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
9J:157354 Martinerie L, Viengchareun S, Delezoide AL, Jaubert F, Sinico M, Prevot S, Boileau P, Meduri G, Lombes M, Low renal mineralocorticoid receptor expression at birth contributes to partial aldosterone resistance in neonates. Endocrinology. 2009 Sep;150(9):4414-24
1J:185583 Metzakopian E, Lin W, Salmon-Divon M, Dvinge H, Andersson E, Ericson J, Perlmann T, Whitsett JA, Bertone P, Ang SL, Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors. Development. 2012 Jul;139(14):2625-34
2*J:130227 Millien G, Beane J, Lenburg M, Tsao PN, Lu J, Spira A, Ramirez MI, Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction. Gene Expr Patterns. 2008 Jan;8(2):124-39
1J:161950 O'Brien KB, Alberich-Jorda M, Yadav N, Kocher O, Diruscio A, Ebralidze A, Levantini E, Sng NJ, Bhasin M, Caron T, Kim D, Steidl U, Huang G, Halmos B, Rodig SJ, Bedford MT, Tenen DG, Kobayashi S, CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells. Development. 2010 Jul;137(13):2147-56
2J:121917 Olesen C, Nyeng P, Kalisz M, Jensen TH, Moller M, Tommerup N, Byskov AG, Global gene expression analysis in fetal mouse ovaries with and without meiosis and comparison of selected genes with meiosis in the testis. Cell Tissue Res. 2007 Apr;328(1):207-21
1J:150185 Reimer R, Helmbold H, Szalay B, Hagel C, Hohenberg H, Deppert W, Bohn W, Nestin modulates glucocorticoid receptor function by cytoplasmic anchoring. PLoS One. 2009;4(6):e6084
1*J:51536 Reyes JC, Barra J, Muchardt C, Camus A, Babinet C, Yaniv M, Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha). EMBO J. 1998 Dec 1;17(23):6979-91
15J:199136 Rog-Zielinska EA, Thomson A, Kenyon CJ, Brownstein DG, Moran CM, Szumska D, Michailidou Z, Richardson J, Owen E, Watt A, Morrison H, Forrester LM, Bhattacharya S, Holmes MC, Chapman KE, Glucocorticoid receptor is required for foetal heart maturation. Hum Mol Genet. 2013 Aug 15;22(16):3269-82
4J:182938 Sevilla LM, Bayo P, Latorre V, Sanchis A, Perez P, Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin. Mol Endocrinol. 2010 Nov;24(11):2166-78
2J:196481 Sevilla LM, Latorre V, Sanchis A, Perez P, Epidermal inactivation of the glucocorticoid receptor triggers skin barrier defects and cutaneous inflammation. J Invest Dermatol. 2013 Feb;133(2):361-70
7J:168512 Simard M, Cote M, Provost PR, Tremblay Y, Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation. Reprod Biol Endocrinol. 2010;8:134
2J:106962 Son GH, Geum D, Chung S, Kim EJ, Jo JH, Kim CM, Lee KH, Kim H, Choi S, Kim HT, Lee CJ, Kim K, Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity. J Neurosci. 2006 Mar 22;26(12):3309-18
10J:89625 Speirs HJ, Seckl JR, Brown RW, Ontogeny of glucocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type-1 gene expression identifies potential critical periods of glucocorticoid susceptibility during development. J Endocrinol. 2004 Apr;181(1):105-16
5J:80418 Thompson A, Han VK, Yang K, Spatial and temporal patterns of expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 messenger RNA and glucocorticoid receptor protein in the murine placenta and uterus during late pregnancy. Biol Reprod. 2002 Dec;67(6):1708-18
5J:90284 Thompson A, Han VK, Yang K, Differential expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 mRNA and glucocorticoid receptor protein during mouse embryonic development. J Steroid Biochem Mol Biol. 2004 Apr;88(4-5):367-75
2J:138125 Umekawa T, Sugiyama T, Kihira T, Murabayashi N, Zhang L, Nagao K, Kamimoto Y, Ma N, Yodoi J, Sagawa N, Overexpression of thioredoxin-1 reduces oxidative stress in the placenta of transgenic mice and promotes fetal growth via glucose metabolism. Endocrinology. 2008 Aug;149(8):3980-8
1J:164654 Valtat B, Dupuis C, Zenaty D, Singh-Estivalet A, Tronche F, Breant B, Blondeau B, Genetic evidence of the programming of beta cell mass and function by glucocorticoids in mice. Diabetologia. 2010 Sep 21;
1*J:166958 Yates LL, Papakrivopoulou J, Long DA, Goggolidou P, Connolly JO, Woolf AS, Dean CH, The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation. Hum Mol Genet. 2010 Dec 1;19(23):4663-76
2*J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1J:196001 Yu H, He K, Li L, Sun L, Tang F, Li R, Ning W, Jin Y, Deletion of STK40 protein in mice causes respiratory failure and death at birth. J Biol Chem. 2013 Feb 22;288(8):5342-52
2J:159121 Zhang M, Liu X, Zhang Y, Zhao J, Loss of betaarrestin1 and betaarrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice. Dev Biol. 2010 Mar 15;339(2):407-17
3J:178360 Zhang M, Teng H, Shi J, Zhang Y, Disruption of beta-arrestins blocks glucocorticoid receptor and severely retards lung and liver development in mice. Mech Dev. 2011 Sep;128(7-10):368-75
2J:123923 Zhou Q, Law AC, Rajagopal J, Anderson WJ, Gray PA, Melton DA, A multipotent progenitor domain guides pancreatic organogenesis. Dev Cell. 2007 Jul;13(1):103-14

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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory