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Gene Expression Literature Summary
Symbol
Name
ID
Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
MGI:95820

23 matching records from 23 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E11.5 E13 E13.5 E14.5 E15 E15.5 E16 E16.5 E17 E18 E18.5 A
In situ protein (section) 2
In situ RNA (section) 1 5 1 2 6 2 1 5 2 11
Northern blot 1
Western blot 1 6
RT-PCR 2 1 1 1 1 4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Grin2a  glutamate receptor, ionotropic, NMDA2A (epsilon 1)   (Synonyms: GluN2A, GluRepsilon1, NMDAR2A, NR2A)
Results  Reference
1*J:81579 Aguado F, Carmona MA, Pozas E, Aguilo A, Martinez-Guijarro FJ, Alcantara S, Borrell V, Yuste R, Ibanez CF, Soriano E, BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2. Development. 2003 Apr;130(7):1267-80
1J:146779 Barros CS, Calabrese B, Chamero P, Roberts AJ, Korzus E, Lloyd K, Stowers L, Mayford M, Halpain S, Muller U, Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4507-12
1J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1J:149533 Fujiyama T, Yamada M, Terao M, Terashima T, Hioki H, Inoue YU, Inoue T, Masuyama N, Obata K, Yanagawa Y, Kawaguchi Y, Nabeshima Y, Hoshino M, Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1. Development. 2009 Jun;136(12):2049-58
2J:101076 Fukaya M, Hayashi Y, Watanabe M, NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons. Eur J Neurosci. 2005 Mar;21(5):1432-6
3J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
2J:106956 Isosaka T, Hattori K, Yagi T, NMDA-receptor proteins are upregulated in the hippocampus of postnatal heterozygous reeler mice. Brain Res. 2006 Feb 16;1073-1074:11-9
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1J:98227 Miyamoto Y, Chen L, Sato M, Sokabe M, Nabeshima T, Pawson T, Sakai R, Mori N, Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor. J Neurosci. 2005 Feb 16;25(7):1826-35
5J:80744 Oshima S, Fukaya M, Masabumi N, Shirakawa T, Oguchi H, Watanabe M, Early onset of NMDA receptor GluR epsilon 1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus. Neurosci Res. 2002 Jul;43(3):239-50
3*J:138696 Sato A, Sekine Y, Saruta C, Nishibe H, Morita N, Sato Y, Sadakata T, Shinoda Y, Kojima T, Furuichi T, Cerebellar development transcriptome database (CDT-DB): profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum. Neural Netw. 2008 Oct;21(8):1056-69
1J:148808 Sawallisch C, Berhorster K, Disanza A, Mantoani S, Kintscher M, Stoenica L, Dityatev A, Sieber S, Kindler S, Morellini F, Schweizer M, Boeckers TM, Korte M, Scita G, Kreienkamp HJ, The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. J Biol Chem. 2009 Apr 3;284(14):9225-36
4J:106962 Son GH, Geum D, Chung S, Kim EJ, Jo JH, Kim CM, Lee KH, Kim H, Choi S, Kim HT, Lee CJ, Kim K, Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity. J Neurosci. 2006 Mar 22;26(12):3309-18
1J:201986 Sun M, Holter SM, Stepan J, Garrett L, Genius J, Kremmer E, Hrabe de Angelis M, Wurst W, Lie DC, Bally-Cuif L, Eder M, Rujescu D, Graw J, Crybb2 coding for betaB2-crystallin affects sensorimotor gating and hippocampal function. Mamm Genome. 2013 Oct;24(9-10):333-48
2J:189050 Wang L, Zhou D, Lee J, Niu H, Faust TW, Frattini S, Kowal C, Huerta PT, Volpe BT, Diamond B, Female mouse fetal loss mediated by maternal autoantibody. J Exp Med. 2012 Jun 4;209(6):1083-9
1J:107735 Wang X, Weiner JA, Levi S, Craig AM, Bradley A, Sanes JR, Gamma protocadherins are required for survival of spinal interneurons. Neuron. 2002 Dec 5;36(5):843-54
4J:28775 Watanabe M, Inoue Y, Sakimura K, Mishina M, Developmental changes in distribution of NMDA receptor channel subunit mRNAs. Neuroreport. 1992 Dec;3(12):1138-40
4J:17090 Watanabe M, Mishina M, Inoue Y, Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina. Brain Res. 1994 Jan 21;634(2):328-32
4J:17875 Watanabe M, Mishina M, Inoue Y, Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum. J Comp Neurol. 1994 May 22;343(4):513-9
4J:18837 Watanabe M, Mishina M, Inoue Y, Distinct gene expression of the N-methyl-D-aspartate receptor channel subunit in peripheral neurons of the mouse sensory ganglia and adrenal gland. Neurosci Lett. 1994 Jan 3;165(1-2):183-6
4J:18903 Watanabe M, Mishina M, Inoue Y, Distinct spatiotemporal distributions of the N-methyl-D-aspartate receptor channel subunit mRNAs in the mouse cervical cord. J Comp Neurol. 1994 Jul 8;345(2):314-9

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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory