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Gene Expression Literature Summary
Symbol
Name
ID
Glul
glutamate-ammonia ligase (glutamine synthetase)
MGI:95739

81 matching records from 81 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E3.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17.5 E18 E18.5 E A
In situ protein (section) 1 2 3 3 1 1 61
In situ RNA (section) 1 1 1 2 1 1 1 2 1 1 1 5
In situ protein (whole mount) 1
In situ reporter (knock in) 1 1
Northern blot 1
Western blot 1 1 1 1 1 3
RT-PCR 1 1 2 1 3 3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Glul  glutamate-ammonia ligase (glutamine synthetase)   (Synonyms: Glns, GS)
Results  Reference
1J:103009 Acosta ML, Kalloniatis M, Christie DL, Creatine transporter localization in developing and adult retina: importance of creatine to retinal function. Am J Physiol Cell Physiol. 2005 Oct;289(4):C1015-23
1J:191149 Alves CH, Sanz Sanz A, Park B, Pellissier LP, Tanimoto N, Beck SC, Huber G, Murtaza M, Richard F, Sridevi Gurubaran I, Garcia Garrido M, Levelt CN, Rashbass P, Le Bivic A, Seeliger MW, Wijnholds J, Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Hum Mol Genet. 2013 Jan 1;22(1):35-50
1J:105896 Ashique AM, Kharazia V, Yaka R, Phamluong K, Peterson AS, Ron D, Localization of the scaffolding protein RACK1 in the developing and adult mouse brain. Brain Res. 2006 Jan 19;1069(1):31-8
1J:171284 Bechade C, Pascual O, Triller A, Bessis A, Nitric oxide regulates astrocyte maturation in the hippocampus: Involvement of NOS2. Mol Cell Neurosci. 2011 Apr;46(4):762-9
1*J:173463 Bejarano-Escobar R, Holguin-Arevalo MS, Montero JA, Francisco-Morcillo J, Martin-Partido G, Macrophage and microglia ontogeny in the mouse visual system can be traced by the expression of Cathepsins B and D. Dev Dyn. 2011 Jul;240(7):1841-55
3J:187511 Besser M, Jagatheaswaran M, Reinhard J, Schaffelke P, Faissner A, Tenascin C regulates proliferation and differentiation processes during embryonic retinogenesis and modulates the de-differentiation capacity of Muller glia by influencing growth factor responsiveness and the extracellular matrix compartment. Dev Biol. 2012 Sep 15;369(2):163-76
5*J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
2J:193325 Boj SF, van Es JH, Huch M, Li VS, Jose A, Hatzis P, Mokry M, Haegebarth A, van den Born M, Chambon P, Voshol P, Dor Y, Cuppen E, Fillat C, Clevers H, Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
1J:199451 Brunne B, Franco S, Bouche E, Herz J, Howell BW, Pahle J, Muller U, May P, Frotscher M, Bock HH, Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by reelin signaling mutant mice. Glia. 2013 Aug;61(8):1347-63
1J:167274 Brunne B, Zhao S, Derouiche A, Herz J, May P, Frotscher M, Bock HH, Origin, maturation, and astroglial transformation of secondary radial glial cells in the developing dentate gyrus. Glia. 2010 Oct;58(13):1553-69
1J:156864 Buchert M, Athineos D, Abud HE, Burke ZD, Faux MC, Samuel MS, Jarnicki AG, Winbanks CE, Newton IP, Meniel VS, Suzuki H, Stacker SA, Nathke IS, Tosh D, Huelsken J, Clarke AR, Heath JK, Sansom OJ, Ernst M, Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo. PLoS Genet. 2010 Jan;6(1):e1000816
1J:174095 Cai Z, Simons DL, Fu XY, Feng GS, Wu SM, Zhang X, Loss of shp2-mediated mitogen-activated protein kinase signaling in muller glial cells results in retinal degeneration. Mol Cell Biol. 2011 Jul;31(14):2973-83
1*J:106181 Chiellini C, Costa M, Novelli SE, Amri EZ, Benzi L, Bertacca A, Cohen P, Del Prato S, Friedman JM, Maffei M, Identification of cathepsin K as a novel marker of adiposity in white adipose tissue. J Cell Physiol. 2003 May;195(2):309-21
1J:184469 Cho SH, Kim JY, Simons DL, Song JY, Le JH, Swindell EC, Jamrich M, Wu SM, Kim S, Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis. Hum Mol Genet. 2012 Jun 15;21(12):2663-76
1J:173617 de Melo J, Peng GH, Chen S, Blackshaw S, The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons. Development. 2011 Jun;138(11):2325-36
1*J:83285 Diaz E, Yang YH, Ferreira T, Loh KC, Okazaki Y, Hayashizaki Y, Tessier-Lavigne M, Speed TP, Ngai J, Analysis of gene expression in the developing mouse retina. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5491-6
1J:110865 Donovan SL, Schweers B, Martins R, Johnson D, Dyer MA, Compensation by tumor suppressor genes during retinal development in mice and humans. BMC Biol. 2006;4:14
1*J:152838 Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD, A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci. 2009 Sep 9;29(36):11399-408
1J:167409 Grimal S, Puech S, Wagener R, Venteo S, Carroll P, Fichard-Carroll A, Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells. Glia. 2010 Dec;58(16):1977-87
2*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
1J:104804 Harada C, Harada T, Nakamura K, Sakai Y, Tanaka K, Parada LF, Effect of p75(NTR) on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye. Dev Biol. 2006 Feb 1;290(1):57-65
3*J:122377 He Y, Hakvoort TB, Vermeulen JL, Lamers WH, Van Roon MA, Glutamine synthetase is essential in early mouse embryogenesis. Dev Dyn. 2007 Jul;236(7):1865-75
1J:206315 Hoffmann SA, Hos D, Kuspert M, Lang RA, Lovell-Badge R, Wegner M, Reiprich S, Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes. Development. 2014 Jan;141(1):39-50
1*J:158209 Ivanova E, Hwang GS, Pan ZH, Characterization of transgenic mouse lines expressing Cre recombinase in the retina. Neuroscience. 2010 Jan 13;165(1):233-43
1J:151918 Jiang H, Xiang M, Subtype specification of GABAergic amacrine cells by the orphan nuclear receptor Nr4a2/Nurr1. J Neurosci. 2009 Aug 19;29(33):10449-59
1J:164295 Jin K, Jiang H, Mo Z, Xiang M, Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors. J Neurosci. 2010 Sep 8;30(36):11902-16
1J:152506 Jin ZB, Hirokawa G, Gui L, Takahashi R, Osakada F, Hiura Y, Takahashi M, Yasuhara O, Iwai N, Targeted deletion of miR-182, an abundant retinal microRNA. Mol Vis. 2009;15:523-33
1J:181926 Jo HS, Kang KH, Joe CO, Kim JW, Pten coordinates retinal neurogenesis by regulating Notch signalling. EMBO J. 2012 Feb 15;31(4):817-28
1*J:132267 Junghans D, Heidenreich M, Hack I, Taylor V, Frotscher M, Kemler R, Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Eur J Neurosci. 2008 Feb;27(3):559-71
1J:143205 Kanadia RN, Clark VE, Punzo C, Trimarchi JM, Cepko CL, Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons. Development. 2008 Dec;135(23):3923-33
1J:123313 Karali M, Peluso I, Marigo V, Banfi S, Identification and characterization of microRNAs expressed in the mouse eye. Invest Ophthalmol Vis Sci. 2007 Feb;48(2):509-15
1J:203004 Karunakaran DK, Congdon S, Guerrette T, Banday AR, Lemoine C, Chhaya N, Kanadia R, The expression analysis of Sfrs10 and Celf4 during mouse retinal development. Gene Expr Patterns. 2013 Dec;13(8):425-36
1J:182578 Kay JN, Chu MW, Sanes JR, MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Nature. 2012 Mar 22;483(7390):465-9
1J:193056 Kechad A, Jolicoeur C, Tufford A, Mattar P, Chow RW, Harris WA, Cayouette M, Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina. J Neurosci. 2012 Nov 28;32(48):17197-210
1*J:152410 Komai T, Iwanari H, Mochizuki Y, Hamakubo T, Shinkai Y, Expression of the mouse PR domain protein Prdm8 in the developing central nervous system. Gene Expr Patterns. 2009 Oct;9(7):503-14
1J:160163 Kurihara T, Kubota Y, Ozawa Y, Takubo K, Noda K, Simon MC, Johnson RS, Suematsu M, Tsubota K, Ishida S, Goda N, Suda T, Okano H, von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina. Development. 2010 May;137(9):1563-71
1J:160796 Lee DH, Zhou LJ, Zhou Z, Xie JX, Jung JU, Liu Y, Xi CX, Mei L, Xiong WC, Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. Blood. 2010 Apr 15;115(15):3136-45
1J:92622 Li S, Mo Z, Yang X, Price SM, Shen MM, Xiang M, Foxn4 controls the genesis of amacrine and horizontal cells by retinal progenitors. Neuron. 2004 Sep 16;43(6):795-807
1J:104339 Li X, Perissi V, Liu F, Rose DW, Rosenfeld MG, Tissue-specific regulation of retinal and pituitary precursor cell proliferation. Science. 2002 Aug 16;297(5584):1180-3
1J:196758 Li YN, Pinzon-Duarte G, Dattilo M, Claudepierre T, Koch M, Brunken WJ, The expression and function of netrin-4 in murine ocular tissues. Exp Eye Res. 2012 Mar;96(1):24-35
1J:184380 Li YN, Radner S, French MM, Pinzon-Duarte G, Daly GH, Burgeson RE, Koch M, Brunken WJ, The gamma3 chain of laminin is widely but differentially expressed in murine basement membranes: expression and functional studies. Matrix Biol. 2012 Mar;31(2):120-34
1J:185949 Licatalosi DD, Yano M, Fak JJ, Mele A, Grabinski SE, Zhang C, Darnell RB, Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. Genes Dev. 2012 Jul 15;26(14):1626-42
1J:146694 Lin YP, Ouchi Y, Satoh S, Watanabe S, Sox2 plays a role in the induction of amacrine and Muller glial cells in mouse retinal progenitor cells. Invest Ophthalmol Vis Sci. 2009 Jan;50(1):68-74
1J:181885 Liu C, Bakeri H, Li T, Swaroop A, Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma. Hum Mol Genet. 2012 Apr 15;21(8):1848-60
1J:198157 Liu C, Lin C, Whitaker DT, Bakeri H, Bulgakov OV, Liu P, Lei J, Dong L, Li T, Swaroop A, Prickle1 is expressed in distinct cell populations of the central nervous system and contributes to neuronal morphogenesis. Hum Mol Genet. 2013 Jun 1;22(11):2234-46
1J:205743 Liu H, Kim SY, Fu Y, Wu X, Ng L, Swaroop A, Forrest D, An isoform of retinoid-related orphan receptor beta directs differentiation of retinal amacrine and horizontal interneurons. Nat Commun. 2013;4:1813
1J:199187 Liu X, Zhang Z, Guo W, Burnstock G, He C, Xiang Z, The superficial glia limitans of mouse and monkey brain and spinal cord. Anat Rec (Hoboken). 2013 Jul;296(7):995-1007
1J:159208 Marchong MN, Yurkowski C, Ma C, Spencer C, Pajovic S, Gallie BL, Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death. PLoS Genet. 2010;6(4):e1000923
1J:131387 Martins RA, Zindy F, Donovan S, Zhang J, Pounds S, Wey A, Knoepfler PS, Eisenman RN, Roussel MF, Dyer MA, N-myc coordinates retinal growth with eye size during mouse development. Genes Dev. 2008 Jan 15;22(2):179-93
1J:174679 Matsuoka RL, Chivatakarn O, Badea TC, Samuels IS, Cahill H, Katayama K, Kumar SR, Suto F, Chedotal A, Peachey NS, Nathans J, Yoshida Y, Giger RJ, Kolodkin AL, Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron. 2011 Aug 11;71(3):460-73
1J:205051 Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Sestan N, Gage FH, Lein ES, Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
1J:89191 Mo Z, Li S, Yang X, Xiang M, Role of the Barhl2 homeobox gene in the specification of glycinergic amacrine cells. Development. 2004 Apr;131(7):1607-18
1J:98488 Mui SH, Kim JW, Lemke G, Bertuzzi S, Vax genes ventralize the embryonic eye. Genes Dev. 2005 May 15;19(10):1249-59
1J:154500 Muto A, Iida A, Satoh S, Watanabe S, The group E Sox genes Sox8 and Sox9 are regulated by Notch signaling and are required for Muller glial cell development in mouse retina. Exp Eye Res. 2009 Oct;89(4):549-58
1J:106623 Nakamura K, Harada C, Namekata K, Harada T, Expression of olig2 in retinal progenitor cells. Neuroreport. 2006 Mar 20;17(4):345-9
2J:180117 Nasonkin IO, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A, Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011 Jul 1;519(10):1914-30
1J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41
1J:81741 Pennesi ME, Cho JH, Yang Z, Wu SH, Zhang J, Wu SM, Tsai MJ, BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. J Neurosci. 2003 Jan 15;23(2):453-61
1J:187354 Poche RA, Furuta Y, Chaboissier MC, Schedl A, Behringer RR, Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Muller glial cell development. J Comp Neurol. 2008 Sep 20;510(3):237-50
3J:199127 Poulos MG, Batra R, Li M, Yuan Y, Zhang C, Darnell RB, Swanson MS, Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice. Hum Mol Genet. 2013 Sep 1;22(17):3547-58
1J:80021 Pringle NP, Yu WP, Howell M, Colvin JS, Ornitz DM, Richardson WD, Fgfr3 expression by astrocytes and their precursors: evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains. Development. 2003 Jan;130(1):93-102
1J:179521 Saghizadeh M, Gribanova Y, Akhmedov NB, Farber DB, ZBED4, a cone and Muller cell protein in human retina, has a different cellular expression in mouse. Mol Vis. 2011;17:2011-8
1J:143264 Satoh S, Watanabe S, TGIF, a homeodomain transcription factor, regulates retinal progenitor cell differentiation. Exp Eye Res. 2008 Dec;87(6):571-9
2J:199787 Saurat N, Andersson T, Vasistha NA, Molnar Z, Livesey FJ, Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development. Neural Dev. 2013;8:14
2J:208341 Seth A, Ye J, Yu N, Guez F, Bedford DC, Neale GA, Cordi S, Brindle PK, Lemaigre FP, Kaestner KH, Sosa-Pineda B, Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment. Development. 2014 Feb;141(3):538-47
1J:198290 Shekarabi M, Lafreniere RG, Gaudet R, Laganiere J, Marcinkiewicz MM, Dion PA, Rouleau GA, Comparative analysis of the expression profile of Wnk1 and Wnk1/Hsn2 splice variants in developing and adult mouse tissues. PLoS One. 2013;8(2):e57807
1J:166950 Shi M, Zheng MH, Liu ZR, Hu ZL, Huang Y, Chen JY, Zhao G, Han H, Ding YQ, DCC is specifically required for the survival of retinal ganglion and displaced amacrine cells in the developing mouse retina. Dev Biol. 2010 Dec 1;348(1):87-96
2J:48100 Shiojiri N, Wada J, Gebhardt R, Heterogeneous carbamoylphosphate synthetase I expression in testicular transplants of fetal mouse liver. Eur J Cell Biol. 1998 Apr;75(4):389-92
5J:26095 Shiojiri N, Wada JI, Tanaka T, Noguchi M, Ito M, Gebhardt R, Heterogeneous hepatocellular expression of glutamine synthetase in developing mouse liver and in testicular transplants of fetal liver. Lab Invest. 1995 Jun;72(6):740-7
2J:101317 Stewart L, Potok MA, Camper SA, Stifani S, Runx1 expression defines a subpopulation of displaced amacrine cells in the developing mouse retina. J Neurochem. 2005 Sep;94(6):1739-45
1J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89
2J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709
1J:135133 Sugimori M, Nagao M, Bertrand N, Parras CM, Guillemot F, Nakafuku M, Combinatorial actions of patterning and HLH transcription factors in the spatiotemporal control of neurogenesis and gliogenesis in the developing spinal cord. Development. 2007 Apr;134(8):1617-29
1J:191133 Tarchini B, Jolicoeur C, Cayouette M, In vivo evidence for unbiased Ikaros retinal lineages using an Ikaros-Cre mouse line driving clonal recombination. Dev Dyn. 2012 Dec;241(12):1973-85
7J:91404 Tokunaga A, Kohyama J, Yoshida T, Nakao K, Sawamoto K, Okano H, Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain. J Neurochem. 2004 Jul;90(1):142-54
3J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1J:78708 Wang YP, Dakubo G, Howley P, Campsall KD, Mazarolle CJ, Shiga SA, Lewis PM, McMahon AP, Wallace VA, Development of normal retinal organization depends on Sonic hedgehog signaling from ganglion cells. Nat Neurosci. 2002 Sep;5(9):831-2
1J:160850 Yoshida T, Guo X, Namekata K, Mitamura Y, Kume S, Harada T, Expression of Epiplakin1 in the developing and adult mouse retina. Jpn J Ophthalmol. 2010 Jan;54(1):85-8
3*J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48
1J:140116 Zhao J, Iida A, Ouchi Y, Satoh S, Watanabe S, M6a is expressed in the murine neural retina and regulates neurite extension. Mol Vis. 2008;14:1623-30

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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory