Gene Expression Literature Summary
|
Symbol Name ID |
Gli3
GLI-Kruppel family member GLI3 MGI:95729 |
| Age | E1.5 | E2 | E2.5 | E3 | E3.5 | E4.5 | E5.5 | E6.5 | E7.5 | E8 | E8.5 | E9 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E19 | E | P |
| Immunohistochemistry (section) | 3 | 2 | 8 | 1 | 5 | 3 | 4 | 1 | 6 | 1 | 2 | 1 | 1 | 1 | 1 | 5 | ||||||||||||||||||
| In situ RNA (section) | 1 | 1 | 1 | 1 | 7 | 2 | 19 | 2 | 30 | 5 | 23 | 3 | 40 | 2 | 19 | 6 | 31 | 1 | 14 | 2 | 13 | 5 | 1 | 8 | 3 | 20 | ||||||||
| Immunohistochemistry (whole mount) | 1 | 1 | ||||||||||||||||||||||||||||||||
| In situ RNA (whole mount) | 1 | 2 | 5 | 12 | 31 | 12 | 62 | 12 | 35 | 6 | 21 | 1 | 7 | 3 | 6 | 1 | 8 | 1 | ||||||||||||||||
| In situ reporter (knock in) | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | ||||||||||||||||||||||||||
| Northern blot | 1 | 1 | 2 | 1 | 1 | 4 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 4 | |||||||||||||||||
| Western blot | 1 | 3 | 2 | 23 | 1 | 50 | 6 | 35 | 1 | 23 | 10 | 7 | 7 | 3 | 2 | 4 | 2 | 8 | ||||||||||||||||
| RT-PCR | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 3 | 12 | 1 | 10 | 2 | 14 | 2 | 17 | 1 | 12 | 1 | 7 | 8 | 7 | 7 | 1 | 13 | 6 | 23 | |||||||
| cDNA clones | 2 | 1 | 1 | 1 | 1 | 1 | 2 | |||||||||||||||||||||||||||
| RNase protection | 1 | 1 | 1 | 2 | 1 |
| Gli3 GLI-Kruppel family member GLI3 (Synonyms: Bph, brachyphalangy) | |
| Results | Reference |
| 4* | J:160294 Abbasi AA, Paparidis Z, Malik S, Bangs F, Schmidt A, Koch S, Lopez-Rios J, Grzeschik KH, Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development. BMC Dev Biol. 2010;10:44 |
| 1 | J:255486 Agbu SO, Liang Y, Liu A, Anderson KV, The small GTPase RSG1 controls a final step in primary cilia initiation. J Cell Biol. 2018 Jan 2;217(1):413-427 |
| 1 | J:121946 Akiyama H, Stadler HS, Martin JF, Ishii TM, Beachy PA, Nakamura T, de Crombrugghe B, Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. Matrix Biol. 2007 May;26(4):224-33 |
| 1 | J:207610 Akiyama R, Kawakami H, Taketo MM, Evans SM, Wada N, Petryk A, Kawakami Y, Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the beta-catenin pathway. Dev Biol. 2014 Mar 1;387(1):37-48 |
| 2 | J:220960 Akiyama R, Kawakami H, Wong J, Oishi I, Nishinakamura R, Kawakami Y, Sall4-Gli3 system in early limb progenitors is essential for the development of limb skeletal elements. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5075-80 |
| 1 | J:130428 Alvarez-Medina R, Cayuso J, Okubo T, Takada S, Marti E, Wnt canonical pathway restricts graded Shh/Gli patterning activity through the regulation of Gli3 expression. Development. 2008 Jan;135(2):237-47 |
| 1 | J:229226 Amaniti EM, Fu C, Lewis S, Saisana M, Magnani D, Mason JO, Theil T, Expansion of the piriform cortex contributes to corticothalamic pathfinding defects in Gli3 conditional mutants. Cereb Cortex. 2015 Feb;25(2):460-71 |
| 4 | J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24 |
| 1 | J:244926 Amaniti EM, Kelman A, Mason JO, Theil T, Cerebral Cortex Expression of Gli3 Is Required for Normal Development of the Lateral Olfactory Tract. PLoS One. 2015;10(10):e0141525 |
| 5* | J:80177 Aoto K, Nishimura T, Eto K, Motoyama J, Mouse GLI3 Regulates Fgf8 Expression and Apoptosis in the Developing Neural Tube, Face, and Limb Bud. Dev Biol. 2002 Nov 15;251(2):320-32 |
| 1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
| 1* | J:181888 Ashe A, Butterfield NC, Town L, Courtney AD, Cooper AN, Ferguson C, Barry R, Olsson F, Liem KF Jr, Parton RG, Wainwright BJ, Anderson KV, Whitelaw E, Wicking C, Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies. Hum Mol Genet. 2012 Apr 15;21(8):1808-23 |
| 1 | J:186055 Ashique AM, Choe Y, Karlen M, May SR, Phamluong K, Solloway MJ, Ericson J, Peterson AS, The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis. Sci Signal. 2009;2(95):ra70 |
| 4* | J:135300 Babbs C, Furniss D, Morriss-Kay GM, Wilkie AO, Polydactyly in the mouse mutant Doublefoot involves altered Gli3 processing and is caused by a large deletion in cis to Indian hedgehog. Mech Dev. 2008 May-Jun;125(5-6):517-26 |
| 1 | J:87948 Bai CB, Stephen D, Joyner AL, All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3. Dev Cell. 2004 Jan;6(1):103-15 |
| 7 | J:283343 Bastida MF, Perez-Gomez R, Trofka A, Zhu J, Rada-Iglesias A, Sheth R, Stadler HS, Mackem S, Ros MA, The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1090-1096 |
| 1* | J:59288 Baur ST, Mai JJ, Dymecki SM, Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity. Development. 2000 Feb;127(3):605-19 |
| 3* | J:70831 Becker MB, Zulch A, Bosse A, Gruss P, Irx1 and Irx2 expression in early lung development. Mech Dev. 2001 Aug;106(1-2):155-8 |
| 1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
| 1 | J:98357 Bell SM, Schreiner CM, Goetz JA, Robbins DJ, Scott WJ Jr, Shh signaling in limb bud ectoderm: Potential role in teratogen-induced postaxial ectrodactyly. Dev Dyn. 2005 Jun;233(2):313-25 |
| 2 | J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606 |
| 1 | J:171190 Bensoussan-Trigano V, Lallemand Y, Saint Cloment C, Robert B, Msx1 and Msx2 in limb mesenchyme modulate digit number and identity. Dev Dyn. 2011 May;240(5):1190-202 |
| 3 | J:171429 Besse L, Neti M, Anselme I, Gerhardt C, Ruther U, Laclef C, Schneider-Maunoury S, Primary cilia control telencephalic patterning and morphogenesis via Gli3 proteolytic processing. Development. 2011 May;138(10):2079-88 |
| 2 | J:259558 Bhattacharyya S, Rainey MA, Arya P, Dutta S, George M, Storck MD, McComb RD, Muirhead D, Todd GL, Gould K, Datta K, Gelineau-van Waes J, Band V, Band H, Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016 Feb 17;6:20727 |
| 1 | J:220864 Billmyre KK, Klingensmith J, Sonic hedgehog from pharyngeal arch 1 epithelium is necessary for early mandibular arch cell survival and later cartilage condensation differentiation. Dev Dyn. 2015 Apr;244(4):564-76 |
| 1* | J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91 |
| 2* | J:108509 Blaess S, Corrales JD, Joyner AL, Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region. Development. 2006 May;133(9):1799-809 |
| 3 | J:121232 Bok J, Dolson DK, Hill P, Ruther U, Epstein DJ, Wu DK, Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear. Development. 2007 May;134(9):1713-22 |
| 2 | J:160580 Borello U, Cobos I, Long JE, McWhirter JR, Murre C, Rubenstein JL, FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Neural Dev. 2008;3:17 |
| 1 | J:316302 Bosch PJ, Fuller LC, Weiner JA, An essential role for the nuclear protein Akirin2 in mouse limb interdigital tissue regression. Sci Rep. 2018 Aug 16;8(1):12240 |
| 3 | J:139130 Breunig JJ, Sarkisian MR, Arellano JI, Morozov YM, Ayoub AE, Sojitra S, Wang B, Flavell RA, Rakic P, Town T, Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13127-32 |
| 1 | J:158523 Brugmann SA, Allen NC, James AW, Mekonnen Z, Madan E, Helms JA, A primary cilia-dependent etiology for midline facial disorders. Hum Mol Genet. 2010 Apr 15;19(8):1577-92 |
| 1 | J:89364 Bulgakov OV, Eggenschwiler JT, Hong DH, Anderson KV, Li T, FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues. Development. 2004 May;131(9):2149-59 |
| 1* | J:237132 Burnicka-Turek O, Steimle JD, Huang W, Felker L, Kamp A, Kweon J, Peterson M, Reeves RH, Maslen CL, Gruber PJ, Yang XH, Shendure J, Moskowitz IP, Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms. Hum Mol Genet. 2016 Jul 15;25(14):3011-3028 |
| 3* | J:39658 Buscher D, Bosse B, Heymer J, Ruther U, Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development. Mech Dev. 1997 Mar;62(2):175-82 |
| 1 | J:48982 Buscher D, Grotewold L, Ruther U, The XtJ allele generates a Gli3 fusion transcript. Mamm Genome. 1998 Aug;9(8):676-8 |
| 5* | J:45211 Buscher D, Ruther U, Expression profile of Gli family members and Shh in normal and mutant mouse limb development. Dev Dyn. 1998 Jan;211(1):88-96 |
| 3 | J:153595 Butterfield NC, Metzis V, McGlinn E, Bruce SJ, Wainwright BJ, Wicking C, Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb. Development. 2009 Oct;136(20):3515-24 |
| 1 | J:87223 Buttitta L, Mo R, Hui CC, Fan CM, Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction. Development. 2003 Dec;130(25):6233-43 |
| 2 | J:239074 Cai H, Liu A, Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14751-14756 |
| 2 | J:251822 Cai H, Liu A, Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord. Dev Biol. 2017 Dec 1;432(1):72-85 |
| 1 | J:148411 Cameron DA, Pennimpede T, Petkovich M, Tulp3 is a critical repressor of mouse hedgehog signaling. Dev Dyn. 2009 May;238(5):1140-9 |
| 1* | J:199480 Cao T, Wang C, Yang M, Wu C, Wang B, Mouse limbs expressing only the Gli3 repressor resemble those of Sonic hedgehog mutants. Dev Biol. 2013 Jul 15;379(2):221-8 |
| 3 | J:109528 Capellini TD, Di Giacomo G, Salsi V, Brendolan A, Ferretti E, Srivastava D, Zappavigna V, Selleri L, Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression. Development. 2006 Jun;133(11):2263-73 |
| 3 | J:169192 Capellini TD, Vaccari G, Ferretti E, Fantini S, He M, Pellegrini M, Quintana L, Di Giacomo G, Sharpe J, Selleri L, Zappavigna V, Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1. Development. 2010 Aug 1;137(15):2559-69 |
| 1 | J:120712 Caspary T, Larkins CE, Anderson KV, The graded response to sonic hedgehog depends on cilia architecture. Dev Cell. 2007 May;12(5):767-78 |
| 3* | J:340395 Castro JP, Yancoskie MN, Marchini M, Belohlavy S, Hiramatsu L, Kucka M, Beluch WH, Naumann R, Skuplik I, Cobb J, Barton NH, Rolian C, Chan YF, An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice. Elife. 2019 Jun 6;8 |
| 3 | J:150524 Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA, Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. Nat Neurosci. 2009 Apr;12(4):409-17 |
| 2* | J:308674 Chang CF, Brown KM, Yang Y, Brugmann SA, Centriolar Protein C2cd3 Is Required for Craniofacial Development. Front Cell Dev Biol. 2021;9:647391 |
| 1 | J:236864 Chang CF, Chang YT, Millington G, Brugmann SA, Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline. PLoS Genet. 2016 Nov;12(11):e1006351 |
| 2 | J:103829 Chen B, Schaevitz LR, McConnell SK, Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17184-9 |
| 1 | J:288298 Chen KQ, Tahara N, Anderson A, Kawakami H, Kawakami S, Nishinakamura R, Pandolfi PP, Kawakami Y, Development of the Proximal-Anterior Skeletal Elements in the Mouse Hindlimb Is Regulated by a Transcriptional and Signaling Network Controlled by Sall4. Genetics. 2020 May;215(1):129-141 |
| 1 | J:151923 Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT, Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. Genes Dev. 2009 Aug 15;23(16):1910-28 |
| 1 | J:339854 Chen SY, Liu FC, The Fgf9-Nolz1-Wnt2 axis regulates morphogenesis of the lung. Development. 2023 Aug 15;150(16):dev201827 |
| 2 | J:98432 Chen Y, Knezevic V, Ervin V, Hutson R, Ward Y, Mackem S, Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh. Development. 2004 May;131(10):2339-47 |
| 1 | J:141874 Cheng W, Yeung CK, Ng YK, Zhang JR, Hui CC, Kim PC, Sonic Hedgehog mediator Gli2 regulates bladder mesenchymal patterning. J Urol. 2008;180(4):1543-50 |
| 3 | J:152259 Cheung HO, Zhang X, Ribeiro A, Mo R, Makino S, Puviindran V, Law KK, Briscoe J, Hui CC, The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling. Sci Signal. 2009;2(76):ra29 |
| 1* | J:71186 Chiang C, Litingtung Y, Harris MP, Simandl BK, Li Y, Beachy PA, Fallon JF, Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function. Dev Biol. 2001 Aug 15;236(2):421-35 |
| 2 | J:155992 Ching S, Vilain E, Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia. Genesis. 2009 Sep;47(9):628-37 |
| 4 | J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037 |
| 1 | J:181474 Christ A, Christa A, Kur E, Lioubinski O, Bachmann S, Willnow TE, Hammes A, LRP2 Is an Auxiliary SHH Receptor Required to Condition the Forebrain Ventral Midline for Inductive Signals. Dev Cell. 2012 Feb 14;22(2):268-78 |
| 1 | J:186552 Christopher KJ, Wang B, Kong Y, Weatherbee SD, Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling. Dev Biol. 2012 Aug 15;368(2):382-92 |
| 1 | J:197449 Coles GL, Ackerman KG, Kif7 is required for the patterning and differentiation of the diaphragm in a model of syndromic congenital diaphragmatic hernia. Proc Natl Acad Sci U S A. 2013 May 21;110(21):E1898-905 |
| 1 | J:228894 Coles GL, Baglia LA, Ackerman KG, KIF7 Controls the Proliferation of Cells of the Respiratory Airway through Distinct Microtubule Dependent Mechanisms. PLoS Genet. 2015 Oct;11(10):e1005525 |
| 1* | J:203431 Collette NM, Yee CS, Murugesh D, Sebastian A, Taher L, Gale NW, Economides AN, Harland RM, Loots GG, Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner. Dev Biol. 2013 Nov 1;383(1):90-105 |
| 1 | J:110732 Compagni A, Logan M, Klein R, Adams RH, Control of skeletal patterning by ephrinB1-EphB interactions. Dev Cell. 2003 Aug;5(2):217-30 |
| 2 | J:291480 Constable S, Long AB, Floyd KA, Schurmans S, Caspary T, The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling. Development. 2020 Feb 3;147(3):dev183301 |
| 2 | J:284605 Coquenlorge S, Yin WC, Yung T, Pan J, Zhang X, Mo R, Belik J, Hui CC, Kim TH, GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis. Cell Rep. 2019 Jun 4;27(10):3006-3018.e4 |
| 2 | J:94461 Corrales JD, Rocco GL, Blaess S, Guo Q, Joyner AL, Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development. 2004 Nov;131(22):5581-90 |
| 3* | J:170598 Coy S, Caamano JH, Carvajal J, Cleary ML, Borycki AG, A Novel Gli3 Enhancer Controls the Gli3 Spatiotemporal Expression Pattern through a TALE Homeodomain Protein Binding Site. Mol Cell Biol. 2011 Apr;31(7):1432-43 |
| 2 | J:167534 Cui C, Chatterjee B, Francis D, Yu Q, SanAgustin JT, Francis R, Tansey T, Henry C, Wang B, Lemley B, Pazour GJ, Lo CW, Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome. Dis Model Mech. 2011 Jan;4(1):43-56 |
| 1 | J:205269 Cui C, Chatterjee B, Lozito TP, Zhang Z, Francis RJ, Yagi H, Swanhart LM, Sanker S, Francis D, Yu Q, San Agustin JT, Puligilla C, Chatterjee T, Tansey T, Liu X, Kelley MW, Spiliotis ET, Kwiatkowski AV, Tuan R, Pazour GJ, Hukriede NA, Lo CW, Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol. 2013 Nov;11(11):e1001720 |
| 3 | J:195725 D'Angelo A, De Angelis A, Avallone B, Piscopo I, Tammaro R, Studer M, Franco B, Ofd1 controls dorso-ventral patterning and axoneme elongation during embryonic brain development. PLoS One. 2012;7(12):e52937 |
| 2* | J:73075 Dahmane N, Sanchez P, Gitton Y, Palma V, Sun T, Beyna M, Weiner H, Ruiz i Altaba A, The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis. Development. 2001 Dec;128(24):5201-12 |
| 1 | J:205544 Dai D, Li L, Huebner A, Zeng H, Guevara E, Claypool DJ, Liu A, Chen J, Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia. Cell Death Differ. 2013 Jan;20(1):130-8 |
| 1* | J:159092 Dai P, Akimaru H, Tanaka Y, Maekawa T, Nakafuku M, Ishii S, Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. J Biol Chem. 1999 Mar 19;274(12):8143-52 |
| 1* | J:80205 Dai P, Shinagawa T, Nomura T, Harada J, Kaul SC, Wadhwa R, Khan MM, Akimaru H, Sasaki H, Colmenares C, Ishii S, Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3. Genes Dev. 2002 Nov 15;16(22):2843-8 |
| 2 | J:212081 Dai ZM, Sun S, Wang C, Huang H, Hu X, Zhang Z, Lu QR, Qiu M, Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling. J Neurosci. 2014 Jun 18;34(25):8467-73 |
| 1 | J:291486 Daniel E, Barlow HR, Sutton GI, Gu X, Htike Y, Cowdin MA, Cleaver O, Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560 |
| 1 | J:65294 Dassule HR, Lewis P, Bei M, Maas R, McMahon AP, Sonic hedgehog regulates growth and morphogenesis of the tooth. Development. 2000 Nov;127(22):4775-85 |
| 2* | J:114714 DeLaurier A, Schweitzer R, Logan M, Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb. Dev Biol. 2006 Nov 1;299(1):22-34 |
| 5 | J:195713 DeSouza KR, Saha M, Carpenter AR, Scott M, McHugh KM, Analysis of the Sonic Hedgehog signaling pathway in normal and abnormal bladder development. PLoS One. 2013;8(1):e53675 |
| 2 | J:313289 Dias JM, Alekseenko Z, Jeggari A, Boareto M, Vollmer J, Kozhevnikova M, Wang H, Matise MP, Alexeyenko A, Iber D, Ericson J, A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells. Sci Adv. 2020 Sep;6(38) |
| 1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
| 4* | J:49164 Ding Q, Motoyama J, Gasca S, Mo R, Sasaki H, Rossant J, Hui CC, Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development. 1998 Jul;125(14):2533-43 |
| 1* | J:178421 Dowdle WE, Robinson JF, Kneist A, Sirerol-Piquer MS, Frints SG, Corbit KC, Zaghloul NA, van Lijnschoten G, Mulders L, Verver DE, Zerres K, Reed RR, Attie-Bitach T, Johnson CA, Garcia-Verdugo JM, Katsanis N, Bergmann C, Reiter JF, Disruption of a ciliary B9 protein complex causes Meckel syndrome. Am J Hum Genet. 2011 Jul 15;89(1):94-110 |
| 2 | J:139256 Driver EC, Pryor SP, Hill P, Turner J, Ruther U, Biesecker LG, Griffith AJ, Kelley MW, Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. J Neurosci. 2008 Jul 16;28(29):7350-8 |
| 2 | J:317998 Du A, Wu X, Chen H, Bai QR, Han X, Liu B, Zhang X, Ding Z, Shen Q, Zhao C, Foxg1 Directly Represses Dbx1 to Confine the POA and Subsequently Regulate Ventral Telencephalic Patterning. Cereb Cortex. 2019 Dec 17;29(12):4968-4981 |
| 14* | J:186282 Du J, Fan Z, Ma X, Wu Y, Liu S, Gao Y, Wang J, Shen Y, Fan M, Wang S, Different expression patterns of Gli1-3 in mouse embryonic maxillofacial development. Acta Histochem. 2012 Oct;114(6):620-5 |
| 2 | J:302201 Duan S, Li H, Zhang Y, Yang S, Chen Y, Qiu B, Huang C, Wang J, Li J, Zhu X, Yan X, Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling. EMBO J. 2021 Jan 15;40(2):e105499 |
| 1 | J:104803 Eggenschwiler JT, Bulgakov OV, Qin J, Li T, Anderson KV, Mouse Rab23 regulates Hedgehog signaling from Smoothened to Gli proteins. Dev Biol. 2006 Feb 1;290(1):1-12 |
| 1* | J:215449 Eguether T, San Agustin JT, Keady BT, Jonassen JA, Liang Y, Francis R, Tobita K, Johnson CA, Abdelhamed ZA, Lo CW, Pazour GJ, IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment. Dev Cell. 2014;31:279-290 |
| 2* | J:296137 Elliott KH, Chen X, Salomone J, Chaturvedi P, Schultz PA, Balchand SK, Servetas JD, Zuniga A, Zeller R, Gebelein B, Weirauch MT, Peterson KA, Brugmann SA, Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks. Elife. 2020 Oct 2;9:e56450 |
| 4 | J:232111 Emechebe U, Kumar P P, Rozenberg JM, Moore B, Firment A, Mirshahi T, Moon AM, T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number. Elife. 2016;5:e07897 |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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