Gene Expression Literature Summary

• Symbol: Gch1
• Name: GTP cyclohydrolase 1
• ID: MGI:95675

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14.5	E15.5	E18.5	P
In situ RNA (section)						1				1	2	2	1	2
RT-PCR	1	1	1	1	1	1	1	3	1					4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gch1  GTP cyclohydrolase 1   (Synonyms: GTPCH, GTP-CH)
Results	Reference
5*	J:219813 Douglas G, Hale AB, Crabtree MJ, Ryan BJ, Hansler A, Watschinger K, Gross SS, Lygate CA, Alp NJ, Channon KM, A requirement for Gch1 and tetrahydrobiopterin in embryonic development. Dev Biol. 2015 Mar 1;399(1):129-38
7*	J:122522 Gil M, McKinney C, Lee MK, Eells JB, Phyillaier MA, Nikodem VM, Regulation of GTP cyclohydrolase I expression by orphan receptor Nurr1 in cell culture and in vivo. J Neurochem. 2007 Apr;101(1):142-50
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
2	J:155057 Hwang DY, Hong S, Jeong JW, Choi S, Kim H, Kim J, Kim KS, Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons. J Neurochem. 2009 Dec;111(5):1202-12
1	J:165266 Liu C, Maejima T, Wyler SC, Casadesus G, Herlitze S, Deneris ES, Pet-1 is required across different stages of life to regulate serotonergic function. Nat Neurosci. 2010 Oct;13(10):1190-8
1	J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1*	J:237675 Wyler SC, Donovan LJ, Yeager M, Deneris E, Pet-1 Controls Tetrahydrobiopterin Pathway and Slc22a3 Transporter Genes in Serotonin Neurons. ACS Chem Neurosci. 2015 Jul 15;6(7):1198-205