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Gene Expression Literature Summary
Symbol
Name
ID
Fmr1
fragile X mental retardation syndrome 1
MGI:95564

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1 E2 E2.5 E3 E7 E7.5 E9 E9.5 E10.5 E11 E11.5 E12.5 E13.5 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E A
In situ protein (section) 1 1 1 3
In situ RNA (section) 1 1 1 1 1 1 1 1 1 1 3
Northern blot 1 1 1 1 1 1 1 2
Western blot 1 1 1 1 2
RT-PCR 1 1 1 1 1 1 1 1 3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Fmr1  fragile X mental retardation syndrome 1   (Synonyms: Fmr-1, FMRP)
Results  Reference
8J:16233 Bachner D, Manca A, Steinbach P, Wohrle D, Just W, Vogel W, Hameister H, Poustka A, Enhanced expression of the murine FMR1 gene during germ cell proliferation suggests a special function in both the male and the female gonad. Hum Mol Genet. 1993 Dec;2(12):2043-50
4J:199841 Brackett DM, Qing F, Amieux PS, Sellers DL, Horner PJ, Morris DR, FMR1 transcript isoforms: association with polyribosomes; regional and developmental expression in mouse brain. PLoS One. 2013;8(3):e58296
2J:148744 Chiba H, Hirasawa R, Kaneda M, Amakawa Y, Li E, Sado T, Sasaki H, De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes. Genesis. 2008 Dec;46(12):768-74
2J:170787 Cunningham CL, Martinez Cerdeno V, Navarro Porras E, Prakash AN, Angelastro JM, Willemsen R, Hagerman PJ, Pessah IN, Berman RF, Noctor SC, Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development. Hum Mol Genet. 2011 Jan 1;20(1):64-79
1J:88217 Hedlund E, Karsten SL, Kudo L, Geschwind DH, Carpenter EM, Identification of a Hoxd10-regulated transcriptional network and combinatorial interactions with Hoxa10 during spinal cord development. J Neurosci Res. 2004 Feb 1;75(3):307-19
1J:173577 Hoki Y, Ikeda R, Mise N, Sakata Y, Ohhata T, Sasaki H, Abe K, Sado T, Incomplete X-inactivation initiated by a hypomorphic Xist allele in the mouse. Development. 2011 Jul;138(13):2649-59
4J:150959 Kalantry S, Purushothaman S, Bowen RB, Starmer J, Magnuson T, Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation. Nature. 2009 Jul 30;460(7255):647-51
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
4*J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
2J:127940 Pacey LK, Doering LC, Developmental expression of FMRP in the astrocyte lineage: implications for fragile X syndrome. Glia. 2007 Nov 15;55(15):1601-9
4J:168545 Saffary R, Xie Z, FMRP Regulates the Transition from Radial Glial Cells to Intermediate Progenitor Cells during Neocortical Development. J Neurosci. 2011 Jan 26;31(4):1427-39
8J:150467 Xie W, Dolzhanskaya N, LaFauci G, Dobkin C, Denman RB, Tissue and developmental regulation of fragile X mental retardation 1 exon 12 and 15 isoforms. Neurobiol Dis. 2009 Jul;35(1):52-62
1J:176126 Xu XL, Zong R, Li Z, Biswas MH, Fang Z, Nelson DL, Gao FB, FXR1P But Not FMRP Regulates the Levels of Mammalian Brain-Specific microRNA-9 and microRNA-124. J Neurosci. 2011 Sep 28;31(39):13705-9
1J:194967 Zongaro S, Hukema R, D'Antoni S, Davidovic L, Barbry P, Catania MV, Willemsen R, Mari B, Bardoni B, The 3' UTR of FMR1 mRNA is a target of miR-101, miR-129-5p and miR-221: implications for the molecular pathology of FXTAS at the synapse. Hum Mol Genet. 2013 May 15;22(10):1971-82

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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory