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Gene Expression Literature Summary
Symbol
Name
ID
Erbb3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
MGI:95411

74 matching records from 74 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2.5 E3.5 E4 E8.5 E9 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E A
In situ protein (section) 1 6 2 1 3 1 2 1 1 1 2 2
In situ RNA (section) 2 2 2 9 1 6 1 2 3 4 2 2 1 2 2 1 2 2
In situ protein (whole mount) 1 1
In situ RNA (whole mount) 1 3 3 2 4 1 5 1 1
Northern blot 1 2
Western blot 1 2 3 2 1 2 1 1 1 2 3 4
RT-PCR 1 1 1 1 2 3 3 4 1 2 1 2 1 2 1 1 5

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Erbb3  v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)   (Synonyms: Erbb-3, Erbb3r, HER3)
Results  Reference
6J:152588 Abe Y, Namba H, Zheng Y, Nawa H, In situ hybridization reveals developmental regulation of ErbB1-4 mRNA expression in mouse midbrain: implication of ErbB receptors for dopaminergic neurons. Neuroscience. 2009 Jun 16;161(1):95-110
1J:67296 Adams RH, Diella F, Hennig S, Helmbacher F, Deutsch U, Klein R, The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration. Cell. 2001 Jan 12;104(1):57-69
2J:171200 Adilakshmi T, Ness-Myers J, Madrid-Aliste C, Fiser A, Tapinos N, A Nuclear Variant of ErbB3 Receptor Tyrosine Kinase Regulates Ezrin Distribution and Schwann Cell Myelination. J Neurosci. 2011 Mar 30;31(13):5106-19
1J:194074 Ahn Y, Sims C, Logue JM, Weatherbee SD, Krumlauf R, Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling. Development. 2013 Feb 1;140(3):583-93
1J:89752 Akiyama H, Chaboissier MC, Behringer RR, Rowitch DH, Schedl A, Epstein JA, de Crombrugghe B, Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6502-7
1J:76593 Bamforth SD, Braganca J, Eloranta JJ, Murdoch JN, Marques FI, Kranc KR, Farza H, Henderson DJ, Hurst HC, Bhattacharya S, Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat Genet. 2001 Dec;29(4):469-74
4J:106953 Bovetti S, De Marchis S, Gambarotta G, Fasolo A, Perroteau I, Puche AC, Bovolin P, Differential expression of neuregulins and their receptors in the olfactory bulb layers of the developing mouse. Brain Res. 2006 Mar 10;1077(1):37-47
3J:154462 Breuskin I, Bodson M, Thelen N, Thiry M, Borgs L, Nguyen L, Lefebvre PP, Malgrange B, Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti. Dev Biol. 2009 Nov 15;335(2):327-39
2J:164699 Breuskin I, Bodson M, Thelen N, Thiry M, Borgs L, Nguyen L, Stolt C, Wegner M, Lefebvre PP, Malgrange B, Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10. J Neurochem. 2010 Sep;114(6):1827-39
3J:67383 Britsch S, Goerich DE, Riethmacher D, Peirano RI, Rossner M, Nave KA, Birchmeier C, Wegner M, The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev. 2001 Jan 1;15(1):66-78
2J:48515 Britsch S, Li L, Kirchhoff S, Theuring F, Brinkmann V, Birchmeier C, Riethmacher D, The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system. Genes Dev. 1998 Jun 15;12(12):1825-36
5*J:94401 Brown N, Deb K, Paria BC, Das SK, Reese J, Embryo-uterine interactions via the neuregulin family of growth factors during implantation in the mouse. Biol Reprod. 2004 Dec;71(6):2003-11
2J:138775 Buac K, Watkins-Chow DE, Loftus SK, Larson DM, Incao A, Gibney G, Pavan WJ, A Sox10 expression screen identifies an amino acid essential for Erbb3 function. PLoS Genet. 2008 Sep;4(9):e1000177
1J:160209 Buac K, Xu M, Cronin J, Weeraratna AT, Hewitt SM, Pavan WJ, NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation. Pigment Cell Melanoma Res. 2009 Dec;22(6):773-84
3J:70080 Calaora V, Rogister B, Bismuth K, Murray K, Brandt H, Leprince P, Marchionni M, Dubois-Dalcq M, Neuregulin signaling regulates neural precursor growth and the generation of oligodendrocytes in vitro. J Neurosci. 2001 Jul 1;21(13):4740-51
1*J:94397 Chan R, Hardy WR, Dankort D, Laing MA, Muller WJ, Modulation of Erbb2 signaling during development: a threshold level of Erbb2 signaling is required for development. Development. 2004 Nov;131(22):5551-60
1J:105025 Cheung M, Chaboissier MC, Mynett A, Hirst E, Schedl A, Briscoe J, The transcriptional control of trunk neural crest induction, survival, and delamination. Dev Cell. 2005 Feb;8(2):179-92
5J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14
6J:141339 Dackor J, Strunk KE, Wehmeyer MM, Threadgill DW, Altered trophoblast proliferation is insufficient to account for placental dysfunction in Egfr null embryos. Placenta. 2007 Nov-Dec;28(11-12):1211-8
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2*J:45302 Erickson SL, O'Shea KS, Ghaboosi N, Loverro L, Frantz G, Bauer M, Lu LH, Moore MW, ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice. Development. 1997 Dec;124(24):4999-5011
1J:162692 Finzsch M, Schreiner S, Kichko T, Reeh P, Tamm ER, Bosl MR, Meijer D, Wegner M, Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol. 2010 May 17;189(4):701-12
1*J:134429 Flagg AE, Earley JU, Svensson EC, FOG-2 attenuates endothelial-to-mesenchymal transformation in the endocardial cushions of the developing heart. Dev Biol. 2007 Apr 1;304(1):308-16
3J:97485 Fox IJ, Kornblum HI, Developmental profile of ErbB receptors in murine central nervous system: implications for functional interactions. J Neurosci Res. 2005 Mar 1;79(5):584-97
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1J:102479 Fu AK, Ip FC, Fu WY, Cheung J, Wang JH, Yung WH, Ip NY, Aberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null mice. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15224-9
1J:33098 Gautam M, Noakes PG, Moscoso L, Rupp F, Scheller RH, Merlie JP, Sanes JR, Defective neuromuscular synaptogenesis in agrin-deficient mutant mice. Cell. 1996 May 17;85(4):525-35
1J:199499 Gerhardt C, Lier JM, Kuschel S, Ruther U, The ciliary protein Ftm is required for ventricular wall and septal development. PLoS One. 2013;8(2):e57545
2*J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50
1J:60190 Golding JP, Trainor P, Krumlauf R, Gassmann M, Defects in pathfinding by cranial neural crest cells in mice lacking the neuregulin receptor ErbB4. Nat Cell Biol. 2000 Feb;2(2):103-9
2J:42441 Goodrich LV, Milenkovic L, Higgins KM, Scott MP, Altered neural cell fates and medulloblastoma in mouse patched mutants. Science. 1997 Aug 22;277(5329):1109-13
3J:119151 Grego-Bessa J, Luna-Zurita L, del Monte G, Bolos V, Melgar P, Arandilla A, Garratt AN, Zang H, Mukouyama YS, Chen H, Shou W, Ballestar E, Esteller M, Rojas A, Perez-Pomares JM, de la Pompa JL, Notch signaling is essential for ventricular chamber development. Dev Cell. 2007 Mar;12(3):415-29
1J:112274 Hart AW, Morgan JE, Schneider J, West K, McKie L, Bhattacharya S, Jackson IJ, Cross SH, Cardiac malformations and midline skeletal defects in mice lacking filamin A. Hum Mol Genet. 2006 Aug 15;15(16):2457-67
1J:74156 Henderson DJ, Conway SJ, Greene ND, Gerrelli D, Murdoch JN, Anderson RH, Copp AJ, Cardiovascular defects associated with abnormalities in midline development in the Loop-tail mouse mutant. Circ Res. 2001 Jul 6;89(1):6-12
2J:80793 Hippenmeyer S, Shneider NA, Birchmeier C, Burden SJ, Jessell TM, Arber S, A role for neuregulin1 signaling in muscle spindle differentiation. Neuron. 2002 Dec 19;36(6):1035-49
1J:175786 Ho AT, Hayashi S, Brohl D, Aurade F, Rattenbach R, Relaix F, Neural Crest Cell Lineage Restricts Skeletal Muscle Progenitor Cell Differentiation through Neuregulin1-ErbB3 Signaling. Dev Cell. 2011 Aug 16;21(2):273-87
1J:185615 Huang Z, Wang Y, Nayak PS, Dammann CE, Sanchez-Esteban J, Stretch-induced fetal type II cell differentiation is mediated via ErbB1-ErbB4 interactions. J Biol Chem. 2012 May 25;287(22):18091-102
1J:82307 Hulander M, Kiernan AE, Blomqvist SR, Carlsson P, Samuelsson EJ, Johansson BR, Steel KP, Enerback S, Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice. Development. 2003 May;130(9):2013-25
3J:96480 Jiang FX, Harrison LC, Laminin-1 and epidermal growth factor family members co-stimulate fetal pancreas cell proliferation and colony formation. Differentiation. 2005 Feb;73(1):45-9
1J:155405 Katayama K, Zine A, Ota M, Matsumoto Y, Inoue T, Fritzsch B, Aruga J, Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice. PLoS One. 2009;4(11):e7786
1J:140017 Komori T, Gyobu H, Ueno H, Kitamura T, Senba E, Morikawa Y, Expression of kin of irregular chiasm-like 3/mKirre in proprioceptive neurons of the dorsal root ganglia and its interaction with nephrin in muscle spindles. J Comp Neurol. 2008 Nov 1;511(1):92-108
1J:33038 Kramer R, Bucay N, Kane DJ, Martin LE, Tarpley JE, Theill LE, Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development. Proc Natl Acad Sci U S A. 1996 May 14;93(10):4833-8
1J:209780 Krcmery J, Gupta R, Sadleir RW, Ahrens MJ, Misener S, Kamide C, Fitchev P, Losordo DW, Crawford SE, Simon HG, Loss of the cytoskeletal protein Pdlim7 predisposes mice to heart defects and hemostatic dysfunction. PLoS One. 2013;8(11):e80809
1J:106261 Kurohara K, Komatsu K, Kurisaki T, Masuda A, Irie N, Asano M, Sudo K, Nabeshima Y, Iwakura Y, Sehara-Fujisawa A, Essential roles of Meltrin beta (ADAM19) in heart development. Dev Biol. 2004 Mar 1;267(1):14-28
1*J:50306 Lakkis MM, Epstein JA, Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart. Development. 1998 Nov;125(22):4359-67
1J:56680 Lakkis MM, Golden JA, O'Shea KS, Epstein JA, Neurofibromin deficiency in mice causes exencephaly and is a modifier for Splotch neural tube defects. Dev Biol. 1999 Aug 1;212(1):80-92
1J:173657 Lavery R, Lardenois A, Ranc-Jianmotamedi F, Pauper E, Gregoire EP, Vigier C, Moreilhon C, Primig M, Chaboissier MC, XY Sox9 embryonic loss-of-function mouse mutants show complete sex reversal and produce partially fertile XY oocytes. Dev Biol. 2011 Jun 1;354(1):111-22
1J:80266 Le Moine C, Fauchey V, Jaber M, Opioid receptor gene expression in dopamine transporter knock-out mice in adult and during development. Neuroscience. 2002;112(1):131-9
6J:102070 Liu J, Nethery D, Kern JA, Neuregulin-1 induces branching morphogenesis in the developing lung through a P13K signal pathway. Exp Lung Res. 2004 Sep;30(6):465-78
1*J:157352 Loftus SK, Baxter LL, Buac K, Watkins-Chow DE, Larson DM, Pavan WJ, Comparison of melanoblast expression patterns identifies distinct classes of genes. Pigment Cell Melanoma Res. 2009 Oct;22(5):611-22
2J:46668 Ma Q, Chen Z, del Barco Barrantes I, de la Pompa JL, Anderson DJ, neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia. Neuron. 1998 Mar;20(3):469-82
1J:92797 Maro GS, Vermeren M, Voiculescu O, Melton L, Cohen J, Charnay P, Topilko P, Neural crest boundary cap cells constitute a source of neuronal and glial cells of the PNS. Nat Neurosci. 2004 Sep;7(9):930-8
1*J:47724 McMahon JA, Takada S, Zimmerman LB, Fan CM, Harland RM, McMahon AP, Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev. 1998 May 15;12(10):1438-52
1J:175212 Meixner A, Karreth F, Kenner L, Penninger JM, Wagner EF, Jun and JunD-dependent functions in cell proliferation and stress response. Cell Death Differ. 2010 Sep;17(9):1409-19
2J:29971 Meyer D, Birchmeier C, Multiple essential functions of neuregulin in development [see comments] [published erratum appears in Nature 1995 Dec 14;378(6558):753]. Nature. 1995 Nov 23;378(6555):386-90
6*J:43309 Meyer D, Yamaai T, Garratt A, Riethmacher-Sonnenberg E, Kane D , Theill LE , Birchmeier C, Isoform-specific expression and function of neuregulin. Development. 1997 Sep;124(18):3575-86
1J:62160 Miettinen PJ, Huotari M, Koivisto T, Ustinov J, Palgi J, Rasilainen S, Lehtonen E, Keski-Oja J, Otonkoski T, Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors. Development. 2000 Jun;127(12):2617-27
5*J:91711 Miyazaki Y, Nakanishi Y, Hieda Y, Tissue interaction mediated by neuregulin-1 and ErbB receptors regulates epithelial morphogenesis of mouse embryonic submandibular gland. Dev Dyn. 2004 Aug;230(4):591-6
1J:190742 Nagashimada M, Ohta H, Li C, Nakao K, Uesaka T, Brunet JF, Amiel J, Trochet D, Wakayama T, Enomoto H, Autonomic neurocristopathy-associated mutations in PHOX2B dysregulate Sox10 expression. J Clin Invest. 2012 Sep 4;122(9):3145-58
1J:197299 Ngo ST, Cole RN, Sunn N, Phillips WD, Noakes PG, Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation. J Cell Sci. 2012 Mar 15;125(Pt 6):1531-43
2J:198779 Nitzan E, Pfaltzgraff ER, Labosky PA, Kalcheim C, Neural crest and Schwann cell progenitor-derived melanocytes are two spatially segregated populations similarly regulated by Foxd3. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12709-14
2J:187102 Ortega MC, Bribian A, Peregrin S, Gil MT, Marin O, de Castro F, Neuregulin-1/ErbB4 signaling controls the migration of oligodendrocyte precursor cells during development. Exp Neurol. 2012 Jun;235(2):610-20
1*J:71878 Paratore C, Goerich DE, Suter U, Wegner M, Sommer L, Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling. Development. 2001 Oct;128(20):3949-61
1J:55391 Pattyn A, Morin X, Cremer H, Goridis C, Brunet JF, The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature. 1999 May 27;399(6734):366-70
1J:43515 Riethmacher D, Sonnenberg-Riethmacher E, Brinkmann V, Yamaai T , Lewin GR , Birchmeier C, Severe neuropathies in mice with targeted mutations in the ErbB3 receptor. Nature. 1997 Oct 16;389(6652):725-30
1*J:87412 Salas-Vidal E, Lomeli H, Imaging filopodia dynamics in the mouse blastocyst. Dev Biol. 2004 Jan 1;265(1):75-89
1*J:38581 Sommer L, Ma Q, Anderson DJ, neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Mol Cell Neurosci. 1996;8(4):221-41
1J:130724 Svensson P, Williams C, Lundeberg J, Ryden P, Bergqvist I, Edlund H, Gene array identification of Ipf1/Pdx1-/- regulated genes in pancreatic progenitor cells. BMC Dev Biol. 2007;7:129
6*J:58414 Toyoda-Ohno H, Obinata M, Matsui Y, Members of the ErbB receptor tyrosine kinases are involved in germ cell development in fetal mouse gonads. Dev Biol. 1999 Nov 15;215(2):399-406
1J:125106 Van de Putte T, Francis A, Nelles L, van Grunsven LA, Huylebroeck D, Neural crest-specific removal of Zfhx1b in mouse leads to a wide range of neurocristopathies reminiscent of Mowat-Wilson syndrome. Hum Mol Genet. 2007 Jun 15;16(12):1423-36
1J:82071 Vermeren M, Maro GS, Bron R, McGonnell IM, Charnay P, Topilko P, Cohen J, Integrity of developing spinal motor columns is regulated by neural crest derivatives at motor exit points. Neuron. 2003 Feb 6;37(3):403-15
8J:135516 Wansbury O, Panchal H, James M, Parry S, Ashworth A, Howard B, Dynamic expression of Erbb pathway members during early mammary gland morphogenesis. J Invest Dermatol. 2008 Apr;128(4):1009-21
4J:60159 Wolpowitz D, Mason TB, Dietrich P, Mendelsohn M, Talmage DA, Role LW, Cysteine-rich domain isoforms of the neuregulin-1 gene are required for maintenance of peripheral synapses. Neuron. 2000 Jan;25(1):79-91
1J:68652 Zilian O, Saner C, Hagedorn L, Lee H, Sauberli E, Suter U, Sommer L, Aguet M, Multiple roles of mouse Numb in tuning developmental cell fates. Curr Biol. 2001 Apr 3;11(7):494-501

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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory