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Gene Expression Literature Summary
epidermal growth factor receptor

111 matching records from 111 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2.5 E3.5 E4 E4.5 E7.5 E8.5 E9 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19 E19.5 E20 E A
In situ protein (section) 1 1 1 2 4 2 3 1 3 4 6 3 10 3 14 2 8 1 4 1 6 3 14
In situ RNA (section) 1 2 1 1 3 1 2 3 3 4 2 2 1 1 1 3 8
In situ protein (whole mount) 1 1 1 1
In situ RNA (whole mount) 1 1
In situ reporter (knock in) 1 1 1
Northern blot 1 1 1 1 1 1 2 1 1 1 1 2 1
Western blot 1 1 1 3 4 5 2 1 1 3 2 1 2 5 1 1 1 14
RT-PCR 2 2 1 3 1 1 1 1 1 2 2 1 1 3 1 5 3 4 1 6 6 5 2 4 1 2 11
RNase protection 1 1 1 1 2 2 2 1 2
Nuclease S1 1 1 1 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Egfr  epidermal growth factor receptor   (Synonyms: 9030024J15Rik, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, Erbb, Errb1, Wa5)
Results  Reference
6J:152588 Abe Y, Namba H, Zheng Y, Nawa H, In situ hybridization reveals developmental regulation of ErbB1-4 mRNA expression in mouse midbrain: implication of ErbB receptors for dopaminergic neurons. Neuroscience. 2009 Jun 16;161(1):95-110
1J:142805 Alcalay NI, Sharma M, Vassmer D, Chapman B, Paul B, Zhou J, Brantley JG, Wallace DP, Maser RL, Vanden Heuvel GB, Acceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1. Am J Physiol Renal Physiol. 2008 Dec;295(6):F1725-34
3*J:36353 Berkowitz EA, Seroogy KB, Schroeder JA, Russell WE, Evans EP, Riedel RF, Phillips HK, Harrison CA, Lee DC, Luetteke NC, Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues. Cell Growth Differ. 1996 Sep;7(9):1271-82
2J:226335 Bhattacharya S, Wheeler H, Leid M, Ganguli-Indra G, Indra AK, Transcription Factor CTIP2 Maintains Hair Follicle Stem Cell Pool and Contributes to Altered Expression of LHX2 and NFATC1. J Invest Dermatol. 2015 Nov;135(11):2593-602
3J:106953 Bovetti S, De Marchis S, Gambarotta G, Fasolo A, Perroteau I, Puche AC, Bovolin P, Differential expression of neuregulins and their receptors in the olfactory bulb layers of the developing mouse. Brain Res. 2006 Mar 10;1077(1):37-47
4*J:94401 Brown N, Deb K, Paria BC, Das SK, Reese J, Embryo-uterine interactions via the neuregulin family of growth factors during implantation in the mouse. Biol Reprod. 2004 Dec;71(6):2003-11
6J:85878 Cai L, Zhang J, Duan E, Dynamic distribution of epidermal growth factor during mouse embryo peri-implantation. Cytokine. 2003 Sep 21;23(6):170-8
2*J:72302 Caric D, Raphael H, Viti J, Feathers A, Wancio D, Lillien L, EGFRs mediate chemotactic migration in the developing telencephalon. Development. 2001 Nov;128(21):4203-16
1J:146695 Carney RS, Cocas LA, Hirata T, Mansfield K, Corbin JG, Differential regulation of telencephalic pallial-subpallial boundary patterning by pax6 and gsh2. Cereb Cortex. 2009 Apr;19(4):745-59
2J:221296 Carrillo-Garcia C, Prochnow S, Simeonova IK, Strelau J, Holzl-Wenig G, Mandl C, Unsicker K, von Bohlen Und Halbach O, Ciccolini F, Growth/differentiation factor 15 promotes EGFR signalling, and regulates proliferation and migration in the hippocampus of neonatal and young adult mice. Development. 2014 Feb;141(4):773-83
1*J:94397 Chan R, Hardy WR, Dankort D, Laing MA, Muller WJ, Modulation of Erbb2 signaling during development: a threshold level of Erbb2 signaling is required for development. Development. 2004 Nov;131(22):5551-60
1J:184017 Chi Z, Zhang J, Tokunaga A, Harraz MM, Byrne ST, Dolinko A, Xu J, Blackshaw S, Gaiano N, Dawson TM, Dawson VL, Botch promotes neurogenesis by antagonizing Notch. Dev Cell. 2012 Apr 17;22(4):707-20
5J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14
15J:141339 Dackor J, Strunk KE, Wehmeyer MM, Threadgill DW, Altered trophoblast proliferation is insufficient to account for placental dysfunction in Egfr null embryos. Placenta. 2007 Nov-Dec;28(11-12):1211-8
1J:32190 Dardik A, Smith RM, Schultz RM, Colocalization of transforming growth factor-alpha and a functional epidermal growth factor receptor (EGFR) to the inner cell mass and preferential localization of the EGFR on the basolateral surface of the trophectoderm in the mouse blastocyst. Dev Biol. 1992 Dec;154(2):396-409
1J:178952 Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, Rank G, Srivastava S, Finlay MJ, Papenfuss AT, Pandolfi PP, Pearson RB, Jane SM, Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell. 2011 Nov 15;20(5):635-48
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:99497 Ellis P, Fagan BM, Magness ST, Hutton S, Taranova O, Hayashi S, McMahon A, Rao M, Pevny L, SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. Dev Neurosci. 2004 Mar-Aug;26(2-4):148-65
1J:118243 Fan X, Warner M, Gustafsson JA, Estrogen receptor beta expression in the embryonic brain regulates development of calretinin-immunoreactive GABAergic interneurons. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19338-43
1J:164437 Ferron SR, Pozo N, Laguna A, Aranda S, Porlan E, Moreno M, Fillat C, de la Luna S, Sanchez P, Arbones ML, Farinas I, Regulated segregation of kinase Dyrk1A during asymmetric neural stem cell division is critical for EGFR-mediated biased signaling. Cell Stem Cell. 2010 Sep 3;7(3):367-79
3J:97485 Fox IJ, Kornblum HI, Developmental profile of ErbB receptors in murine central nervous system: implications for functional interactions. J Neurosci Res. 2005 Mar 1;79(5):584-97
1J:84572 Francone OL, Subbaiah PV, van Tol A, Royer L, Haghpassand M, Abnormal phospholipid composition impairs HDL biogenesis and maturation in mice lacking Abca1. Biochemistry. 2003 Jul 22;42(28):8569-78
3J:149918 Fuchs S, Herzog D, Sumara G, Buchmann-Moller S, Civenni G, Wu X, Chrostek-Grashoff A, Suter U, Ricci R, Relvas JB, Brakebusch C, Sommer L, Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1. Cell Stem Cell. 2009 Mar 6;4(3):236-47
2J:83511 Fujino M, Osumi N, Ninomiya Y, Iseki S, Shibasaki Y, Eto K, Disappearance of epidermal growth factor receptor is essential in the fusion of the nasal epithelium. Anat Sci Int. 2003 Mar;78(1):25-35
1J:93503 Golding JP, Tsoni S, Dixon M, Yee KT, Partridge TA, Beauchamp JR, Gassmann M, Zammit PS, Heparin-binding EGF-like growth factor shows transient left-right asymmetrical expression in mouse myotome pairs. Gene Expr Patterns. 2004 Nov;5(1):3-9
5*J:44484 Gresik EW, Kashimata M, Kadoya Y, Mathews R, Minami N, Yamashina S, Expression of epidermal growth factor receptor in fetal mouse submandibular gland detected by a biotinyltyramide-based catalyzed signal amplification method. J Histochem Cytochem. 1997 Dec;45(12):1651-7
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
1J:214578 Hassemer EL, Endres B, Toonen JA, Ronchetti A, Dubielzig R, Sidjanin DJ, ADAM17 transactivates EGFR signaling during embryonic eyelid closure. Invest Ophthalmol Vis Sci. 2013 Jan;54(1):132-40
3J:123565 Hayakawa-Yano Y, Nishida K, Fukami S, Gotoh Y, Hirano T, Nakagawa T, Shimazaki T, Okano H, Epidermal growth factor signaling mediated by grb2 associated binder1 is required for the spatiotemporally regulated proliferation of olig2-expressing progenitors in the embryonic spinal cord. Stem Cells. 2007 Jun;25(6):1410-22
2J:95759 Hayashi Y, Liu CY, Jester JJ, Hayashi M, Wang IJ, Funderburgh JL, Saika S, Roughley PJ, Kao CW, Kao WW, Excess biglycan causes eyelid malformation by perturbing muscle development and TGF-alpha signaling. Dev Biol. 2005 Jan 1;277(1):222-34
3J:171969 He Y, Zhang H, Yu L, Gunel M, Boggon TJ, Chen H, Min W, Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development. Sci Signal. 2010;3(116):ra26
1J:99584 Hitz C, Vogt-Weisenhorn D, Ruiz P, Wurst W, Floss T, Progressive loss of the spongiotrophoblast layer of Birc6/Bruce mutants results in embryonic lethality. Genesis. 2005 Jun;42(2):91-103
1J:185615 Huang Z, Wang Y, Nayak PS, Dammann CE, Sanchez-Esteban J, Stretch-induced fetal type II cell differentiation is mediated via ErbB1-ErbB4 interactions. J Biol Chem. 2012 May 25;287(22):18091-102
2J:36699 Iamaroon A, Tait B, Diewert VM, Cell proliferation and expression of EGF, TGF-alpha, and EGF receptor in the developing primary palate. J Dent Res. 1996 Aug;75(8):1534-9
1J:199909 Im SK, Jeong H, Jeong HW, Kim KT, Hwang D, Ikegami M, Kong YY, Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice. PLoS One. 2013;8(3):e58511
6J:36479 Jaskoll T, Choy HA, Chen H, Melnick M, Developmental expression and CORT-regulation of TGF-beta and EGF receptor mRNA during mouse palatal morphogenesis: correlation between CORT-induced cleft palate and TGF-beta 2 mRNA expression. Teratology. 1996 Jul;54(1):34-44
1J:69420 Jaskoll T, Melnick M, Submandibular gland morphogenesis: stage-specific expression of TGF-alpha/EGF, IGF, TGF-beta, TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-beta2, TGF-beta3, and EGF-r null mutations. Anat Rec. 1999 Nov 1;256(3):252-68
3J:96480 Jiang FX, Harrison LC, Laminin-1 and epidermal growth factor family members co-stimulate fetal pancreas cell proliferation and colony formation. Differentiation. 2005 Feb;73(1):45-9
1J:104361 Jiang ST, Chiou YY, Wang E, Lin HK, Lin YT, Chi YC, Wang CK, Tang MJ, Li H, Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of pkd1. Am J Pathol. 2006 Jan;168(1):205-20
2J:99502 Jimenez-Farfan D, Guevara J, Zenteno E, Malagon H, Hernandez-Guerrero JC, EGF-R and erbB-2 in murine tooth development after ethanol exposure. Birth Defects Res A Clin Mol Teratol. 2005 Feb;73(2):65-71
1*J:141686 Jin C, Yin F, Lin M, Li H, Wang Z, Weng J, Liu M, Da Dong X, Qu J, Tu L, GPR48 regulates epithelial cell proliferation and migration by activating EGFR during eyelid development. Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4245-53
1*J:153715 Jin N, Cho SN, Raso MG, Wistuba I, Smith Y, Yang Y, Kurie JM, Yen R, Evans CM, Ludwig T, Jeong JW, DeMayo FJ, Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis. Development. 2009 Oct;136(19):3347-56
1J:178678 Karus M, Denecke B, Ffrench-Constant C, Wiese S, Faissner A, The extracellular matrix molecule tenascin C modulates expression levels and territories of key patterning genes during spinal cord astrocyte specification. Development. 2011 Dec;138(24):5321-31
8J:38205 Kashimata M, Gresik EW, Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the alpha6-integrin subunit. Dev Dyn. 1997 Feb;208(2):149-61
1J:126813 Kato S, Mohri Y, Matsuo T, Ogawa E, Umezawa A, Okuyama R, Nishimori K, Eye-open at birth phenotype with reduced keratinocyte motility in LGR4 null mice. FEBS Lett. 2007 Oct 2;581(24):4685-90
1J:224724 Kawaguchi D, Furutachi S, Kawai H, Hozumi K, Gotoh Y, Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis. Nat Commun. 2013;4:1880
4J:88398 Kumabe S, Immunohistochemical study of genesis of the mouse oral vestibule. Okajimas Folia Anat Jpn. 2003 Oct;80(4):93-102
2J:168643 Kusaka M, Katoh-Fukui Y, Ogawa H, Miyabayashi K, Baba T, Shima Y, Sugiyama N, Sugimoto Y, Okuno Y, Kodama R, Iizuka-Kogo A, Senda T, Sasaoka T, Kitamura K, Aizawa S, Morohashi K, Abnormal epithelial cell polarity and ectopic epidermal growth factor receptor (EGFR) expression induced in Emx2 KO embryonic gonads. Endocrinology. 2010 Dec;151(12):5893-904
1J:107400 Laurikkala J, Mikkola ML, James M, Tummers M, Mills AA, Thesleff I, p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development. 2006 Apr;133(8):1553-63
2J:200550 Le Pichon CE, Dominguez SL, Solanoy H, Ngu H, Lewin-Koh N, Chen M, Eastham-Anderson J, Watts R, Scearce-Levie K, EGFR inhibitor erlotinib delays disease progression but does not extend survival in the SOD1 mouse model of ALS. PLoS One. 2013;8(4):e62342
1J:84743 Li G, Gustafson-Brown C, Hanks SK, Nason K, Arbeit JM, Pogliano K, Wisdom RM, Johnson RS, c-Jun is essential for organization of the epidermal leading edge. Dev Cell. 2003 Jun;4(6):865-77
1J:184363 Li H, Chou SJ, Hamasaki T, Perez-Garcia CG, O'Leary DD, Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations. Neural Dev. 2012;7:10
2*J:174485 Lillien L, Gulacsi A, Environmental signals elicit multiple responses in dorsal telencephalic progenitors by threshold-dependent mechanisms. Cereb Cortex. 2006 Jul;16 Suppl 1:i74-81
1J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19
6J:102070 Liu J, Nethery D, Kern JA, Neuregulin-1 induces branching morphogenesis in the developing lung through a P13K signal pathway. Exp Lung Res. 2004 Sep;30(6):465-78
2J:164479 Lozovatsky L, Abayasekara N, Piawah S, Walther Z, CASK deletion in intestinal epithelia causes mislocalization of LIN7C and the DLG1/Scrib polarity complex without affecting cell polarity. Mol Biol Cell. 2009 Nov;20(21):4489-99
1J:208733 Ma A, Wang L, Gao Y, Chang Z, Peng H, Zeng N, Gui YS, Tian X, Li X, Cai B, Zhang H, Xu KF, Tsc1 deficiency-mediated mTOR hyperactivation in vascular endothelial cells causes angiogenesis defects and embryonic lethality. Hum Mol Genet. 2014 Feb 1;23(3):693-705
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5*J:91711 Miyazaki Y, Nakanishi Y, Hieda Y, Tissue interaction mediated by neuregulin-1 and ErbB receptors regulates epithelial morphogenesis of mouse embryonic submandibular gland. Dev Dyn. 2004 Aug;230(4):591-6
1J:77927 Muto S, Aiba A, Saito Y, Nakao K, Nakamura K, Tomita K, Kitamura T, Kurabayashi M, Nagai R, Higashihara E, Harris PC, Katsuki M, Horie S, Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant. Hum Mol Genet. 2002 Jul 15;11(15):1731-42
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1J:206807 Staal B, Williams BO, Beier F, Vande Woude GF, Zhang YW, Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2590-5
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1J:97661 Tadano M, Edamatsu H, Minamisawa S, Yokoyama U, Ishikawa Y, Suzuki N, Saito H, Wu D, Masago-Toda M, Yamawaki-Kataoka Y, Setsu T, Terashima T, Maeda S, Satoh T, Kataoka T, Congenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon. Mol Cell Biol. 2005 Mar;25(6):2191-9
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7J:157544 Tsai NP, Tsui YC, Pintar JE, Loh HH, Wei LN, Kappa opioid receptor contributes to EGF-stimulated neurite extension in development. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3216-21
3J:91730 Verma-Kurvari S, Parada LF, Identification of tyrosine kinases expressed in the male mouse gubernaculum during development. Dev Dyn. 2004 Aug;230(4):660-5
1J:45249 Volpe MV, Martin A, Vosatka RJ, Mazzoni CL, Nielsen HC, Hoxb-5 expression in the developing mouse lung suggests a role in branching morphogenesis and epithelial cell fate. Histochem Cell Biol. 1997 Dec;108(6):495-504
1J:64018 Wang CC, Biben C, Robb L, Nassir F, Barnett L, Davidson NO, Koentgen F, Tarlinton D, Harvey RP, Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera. Dev Biol. 2000 Aug 15;224(2):152-67
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