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Gene Expression Literature Summary
Symbol
Name
ID
Ext1
exostoses (multiple) 1
MGI:894663

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E5.5 E6.5 E7.5 E8.5 E9.5 E10.5 E11.5 E12.5 E13 E13.5 E14.5 E16 E16.5 E18 E18.5 A
In situ RNA (section) 1 1 1 1 1 1 2 1 2 1
In situ RNA (whole mount) 1 3 2 3 1
Northern blot 1
RT-PCR 1 1 1 1 1 1 1 1 2
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Ext1  exostoses (multiple) 1  
Results  Reference
1J:150524 Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA, Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. Nat Neurosci. 2009 Apr;12(4):409-17
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:104933 Hilton MJ, Gutierrez L, Martinez DA, Wells DE, EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development. Bone. 2005 Mar;36(3):379-86
2J:86465 Inatani M, Irie F, Plump AS, Tessier-Lavigne M, Yamaguchi Y, Mammalian brain morphogenesis and midline axon guidance require heparan sulfate. Science. 2003 Nov 7;302(5647):1044-6
7J:82657 Inatani M, Yamaguchi Y, Gene expression of EXT1 and EXT2 during mouse brain development. Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):129-36
2J:152572 Iwao K, Inatani M, Matsumoto Y, Ogata-Iwao M, Takihara Y, Irie F, Yamaguchi Y, Okinami S, Tanihara H, Heparan sulfate deficiency leads to Peters anomaly in mice by disturbing neural crest TGF-beta2 signaling. J Clin Invest. 2009 Jul;119(7):1997-2008
1J:158330 Iwao K, Inatani M, Ogata-Iwao M, Yamaguchi Y, Okinami S, Tanihara H, Heparan sulfate deficiency in periocular mesenchyme causes microphthalmia and ciliary body dysgenesis. Exp Eye Res. 2010 Jan;90(1):81-8
7J:49122 Lin X, Gan L, Klein WH, Wells D, Expression and functional analysis of mouse EXT1, a homolog of the human multiple exostoses type 1 gene. Biochem Biophys Res Commun. 1998 Jul 30;248(3):738-43
2*J:64021 Lin X, Wei G, Shi Z, Dryer L, Esko JD, Wells DE, Matzuk MM, Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. Dev Biol. 2000 Aug 15;224(2):299-311
1J:42532 Lin X, Wells D, Isolation of the mouse cDNA homologous to the human EXT1 gene responsible for Hereditary Multiple Exostoses. DNA Seq. 1997;7(3-4):199-202
1J:170582 Mundy C, Yasuda T, Kinumatsu T, Yamaguchi Y, Iwamoto M, Enomoto-Iwamoto M, Koyama E, Pacifici M, Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol. 2011 Mar 1;351(1):70-81
7*J:63309 Stickens D, Brown D, Evans GA, EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis. Dev Dyn. 2000 Jul;218(3):452-64
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6

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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory