Gene Expression Literature Summary

• Symbol: Mir21a
• Name: microRNA 21a
• ID: MGI:2676885

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E18.5	E	P
In situ RNA (section)																1
Northern blot							1
RT-PCR	1	1	1	1	1	2	1	1	1	3	1	1	1	2	1	1	1	6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mir21a  microRNA 21a   (Synonyms: Mirn21, mmu-mir-21, mmu-mir-21a)
Results	Reference
1	J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26
5	J:197235 Bhandari A, Gordon W, Dizon D, Hopkin AS, Gordon E, Yu Z, Andersen B, The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: modulation of the miR-21 target MSH2 by RNA-binding protein DND1. Oncogene. 2013 Mar 21;32(12):1497-507
3*	J:152495 Carraro G, El-Hashash A, Guidolin D, Tiozzo C, Turcatel G, Young BM, De Langhe SP, Bellusci S, Shi W, Parnigotto PP, Warburton D, miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol. 2009 Sep 15;333(2):238-50
1	J:186203 Chen Z, Wu J, Yang C, Fan P, Balazs L, Jiao Y, Lu M, Gu W, Li C, Pfeffer LM, Tigyi G, Yue J, DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice. J Biol Chem. 2012 Jun 1;287(23):19018-28
1	J:151625 Cordes KR, Sheehy NT, White MP, Berry EC, Morton SU, Muth AN, Lee TH, Miano JM, Ivey KN, Srivastava D, miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature. 2009 Aug 6;460(7256):705-10
2	J:317152 Dehghan Z, Mohammadi-Yeganeh S, Rezaee D, Salehi M, MicroRNA-21 is involved in oocyte maturation, blastocyst formation, and pre-implantation embryo development. Dev Biol. 2021 Dec;480:69-77
3	J:138346 Dogini DB, Ribeiro PA, Rocha C, Pereira TC, Lopes-Cendes I, MicroRNA expression profile in murine central nervous system development. J Mol Neurosci. 2008 Jul;35(3):331-7
1	J:200563 Fan P, Chen Z, Tian P, Liu W, Jiao Y, Xue Y, Bhattacharya A, Wu J, Lu M, Guo Y, Cui Y, Gu W, Gu W, Yue J, miRNA biogenesis enzyme Drosha is required for vascular smooth muscle cell survival. PLoS One. 2013;8(4):e60888
2	J:182094 Huang ZP, Chen JF, Regan JN, Maguire CT, Tang RH, Dong XR, Majesky MW, Wang DZ, Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects. Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2575-86
2	J:316130 Knezevic I, Patel A, Sundaresan NR, Gupta MP, Solaro RJ, Nagalingam RS, Gupta M, A novel cardiomyocyte-enriched microRNA, miR-378, targets insulin-like growth factor 1 receptor: implications in postnatal cardiac remodeling and cell survival. J Biol Chem. 2012 Apr 13;287(16):12913-26
1	J:172088 Pan Y, Balazs L, Tigyi G, Yue J, Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality. Biochem Biophys Res Commun. 2011 May 13;408(3):369-74
5	J:119483 Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA, Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007 Mar 15;21(6):644-8
2	J:111684 Thomson JM, Newman M, Parker JS, Morin-Kensicki EM, Wright T, Hammond SM, Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev. 2006 Aug 15;20(16):2202-7