Gene Expression Literature Summary

• Symbol: Trpm6
• Name: transient receptor potential cation channel, subfamily M, member 6
• ID: MGI:2675603

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E4.5	E5.5	E6.5	E7.5	E8.5	E9.5	E10.5	E11.5	E12	E12.5	E13.5	E14	E14.5	E15.5	E16.5	E17	E17.5	E18	E18.5	P
Immunohistochemistry (section)																				1
In situ RNA (section)					1								1				1			2
In situ reporter (knock in)						1
Northern blot	1	1	1	1	1	1	1	1		1	1		1	1	1		1		1
RT-PCR							1	1	1	1		1	3		1	1	1	2	2	7

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Trpm6  transient receptor potential cation channel, subfamily M, member 6   (Synonyms: CHAK2)
Results	Reference
3*	J:161879 Asai Y, Holt JR, Geleoc GS, A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea. J Assoc Res Otolaryngol. 2010 Mar;11(1):27-37
5	J:239386 Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim OA, Sotlar K, Schurmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T, Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. Elife. 2016 Dec 19;5:e20914
5	J:229122 Cuffe JS, Steane S, Moritz KM, Paravicini TM, Differential mRNA expression and glucocorticoid-mediated regulation of TRPM6 and TRPM7 in the heart and kidney throughout murine pregnancy and development. PLoS One. 2015;10(2):e0117978
6	J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014
1*	J:306141 Franken GAC, Seker M, Bos C, Siemons LAH, van der Eerden BCJ, Christ A, Hoenderop JGJ, Bindels RJM, Muller D, Breiderhoff T, de Baaij JHF, Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects. Sci Rep. 2021 Apr 15;11(1):8217
3	J:148796 Lechner SG, Frenzel H, Wang R, Lewin GR, Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development. EMBO J. 2009 May 20;28(10):1479-91
1	J:286893 Ogata K, Tsumuraya T, Oka K, Shin M, Okamoto F, Kajiya H, Katagiri C, Ozaki M, Matsushita M, Okabe K, The crucial role of the TRPM7 kinase domain in the early stage of amelogenesis. Sci Rep. 2017 Dec 22;7(1):18099
4*	J:155900 Staaf S, Franck MC, Marmigere F, Mattsson JP, Ernfors P, Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons. Gene Expr Patterns. 2010 Jan;10(1):65-74
16*	J:153718 Walder RY, Yang B, Stokes JB, Kirby PA, Cao X, Shi P, Searby CC, Husted RF, Sheffield VC, Mice defective in Trpm6 show embryonic mortality and neural tube defects. Hum Mol Genet. 2009 Nov 15;18(22):4367-75