Gene Expression Literature Summary

• Symbol: Dnd1
• Name: DND microRNA-mediated repression inhibitor 1
• ID: MGI:2447763

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E18.5	P
Immunohistochemistry (section)							1	2	2
In situ RNA (section)						1	2	1				1
Immunohistochemistry (whole mount)	1	1	1							1
In situ RNA (whole mount)	1	1	1		1	1	1	3	1
In situ reporter (knock in)	1	1	1	1		1	1	2	1	2	2	1
Northern blot												1
Western blot						1	2	1	3			2
RT-PCR	1						3					3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dnd1  DND microRNA-mediated repression inhibitor 1   (Synonyms: MGC:41452, RBMS4, Ter)
Results	Reference
3*	J:118625 Bhattacharya C, Aggarwal S, Zhu R, Kumar M, Zhao M, Meistrich ML, Matin A, The mouse dead-end gene isoform alpha is necessary for germ cell and embryonic viability. Biochem Biophys Res Commun. 2007 Mar 30;355(1):194-9
2	J:149469 Cook MS, Coveney D, Batchvarov I, Nadeau JH, Capel B, BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice. Dev Biol. 2009 Apr 15;328(2):377-83
1	J:167041 Cook MS, Munger SC, Nadeau JH, Capel B, Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development. 2011 Jan;138(1):23-32
1*	J:288127 Imai A, Hagiwara Y, Niimi Y, Tokumoto T, Saga Y, Suzuki A, Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence. PLoS One. 2020;15(4):e0232047
4*	J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
1	J:214809 Moniot B, Ujjan S, Champagne J, Hirai H, Aritake K, Nagata K, Dubois E, Nidelet S, Nakamura M, Urade Y, Poulat F, Boizet-Bonhoure B, Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis. Development. 2014 Sep;141(18):3561-71
3	J:334114 Ruthig VA, Hatkevich T, Hardy J, Friedersdorf MB, Mayere C, Nef S, Keene JD, Capel B, The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation. PLoS Genet. 2023 Mar;19(3):e1010656
11	J:334500 Ruthig VA, Yokonishi T, Friedersdorf MB, Batchvarova S, Hardy J, Garness JA, Keene JD, Capel B, A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells. Biol Reprod. 2021 Apr 1;104(4):861-874
10	J:230058 Suzuki A, Niimi Y, Shinmyozu K, Zhou Z, Kiso M, Saga Y, Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development. EMBO Rep. 2016 Jan;17(1):37-46
1	J:156642 Weber S, Eckert D, Nettersheim D, Gillis AJ, Schafer S, Kuckenberg P, Ehlermann J, Werling U, Biermann K, Looijenga LH, Schorle H, Critical function of AP-2 gamma/TCFAP2C in mouse embryonic germ cell maintenance. Biol Reprod. 2010 Jan;82(1):214-23
3	J:86640 Weidinger G, Stebler J, Slanchev K, Dumstrei K, Wise C, Lovell-Badge R, Thisse C, Thisse B, Raz E, dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival. Curr Biol. 2003 Aug 19;13(16):1429-34
3	J:301042 Wright D, Kiso M, Saga Y, Genetic and structural analysis of the in vivo functional redundancy between murine NANOS2 and NANOS3. Development. 2021 Jan 11;148(1):dev191916
11*	J:98580 Youngren KK, Coveney D, Peng X, Bhattacharya C, Schmidt LS, Nickerson ML, Lamb BT, Deng JM, Behringer RR, Capel B, Rubin EM, Nadeau JH, Matin A, The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours. Nature. 2005 May 19;435(7040):360-4
1	J:164224 Zhu R, Heaney J, Nadeau JH, Ali S, Matin A, Deficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors. Cancer Res. 2010 Sep 15;70(18):7264-72