Gene Expression Literature Summary

• Symbol: Lrig3
• Name: leucine-rich repeats and immunoglobulin-like domains 3
• ID: MGI:2443955

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8.5	E9.5	E10	E10.5	E11.5	E12.5	E13	E14.5	E15.5	E16	E16.5	E17	P
Immunohistochemistry (section)												1		1
In situ RNA (section)					1	1			3	1		1		2
In situ RNA (whole mount)	1	2	1	1	2
In situ reporter (knock in)			1		1		2	1			1			1
Western blot														1
RT-PCR										1			1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lrig3  leucine-rich repeats and immunoglobulin-like domains 3   (Synonyms: 9030421L11Rik, 9130004I02Rik, 9430095K15Rik, mKIAA3016)
Results	Reference
5	J:142510 Abraira VE, Del Rio T, Tucker AF, Slonimsky J, Keirnes HL, Goodrich LV, Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear. Development. 2008 Dec;135(24):4091-9
4*	J:308929 De Vincenti AP, Alsina FC, Ferrero Restelli F, Hedman H, Ledda F, Paratcha G, Lrig1 and Lrig3 cooperate to control Ret receptor signaling, sensory axonal growth and epidermal innervation. Development. 2021 Aug 15;148(16):dev197020
1*	J:202451 Del Rio T, Nishitani AM, Yu WM, Goodrich LV, In vivo analysis of lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013 Sep;9(9):e1003824
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
2*	J:143398 Homma S, Shimada T, Hikake T, Yaginuma H, Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo. Gene Expr Patterns. 2009 Jan;9(1):1-26
3	J:149994 Hughes DS, Keynes RJ, Tannahill D, Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation. BMC Dev Biol. 2009;9:30
1	J:67920 Leighton PA, Mitchell KJ, Goodrich LV, Lu X, Pinson K, Scherz P, Skarnes WC, Tessier-Lavigne M, Defining brain wiring patterns and mechanisms through gene trapping in mice. Nature. 2001 Mar 8;410(6825):174-9
1*	J:217538 Lui JH, Nowakowski TJ, Pollen AA, Javaherian A, Kriegstein AR, Oldham MC, Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex. Nature. 2014 Nov 13;515(7526):264-8
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:330740 Narayanan R, Pham L, Kerimoglu C, Watanabe T, Castro Hernandez R, Sokpor G, Ulmke PA, Kiszka KA, Tonchev AB, Rosenbusch J, Seong RH, Teichmann U, Frahm J, Fischer A, Bonn S, Stoykova A, Staiger JF, Tuoc T, Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex. iScience. 2018 Jun 29;4:109-126
1*	J:143778 Tamplin OJ, Cox BJ, Rossant J, Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Dev Biol. 2011 Dec 15;360(2):415-25
2*	J:141291 Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H, Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics. 2008;9(1):511
4	J:227692 van Erp S, van den Heuvel DM, Fujita Y, Robinson RA, Hellemons AJ, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ, Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases. Dev Cell. 2015 Dec 7;35(5):537-52