Gene Expression Literature Summary

• Symbol: Usp7
• Name: ubiquitin specific peptidase 7
• ID: MGI:2182061

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E7.5	E8.5	E9.5	E10	E10.5	E11.5	E13.5	E14.5	E15.5	E18.5	P
Immunohistochemistry (section)		2					1	1	1		1	3
Immunohistochemistry (whole mount)	1											1
In situ reporter (knock in)	1	1	1	1		1
Western blot			1		1			2	2			2
RT-PCR										1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Usp7  ubiquitin specific peptidase 7   (Synonyms: 2210010O09Rik, Hausp)
Results	Reference
2	J:225041 Hasegawa K, Sin HS, Maezawa S, Broering TJ, Kartashov AV, Alavattam KG, Ichijima Y, Zhang F, Bacon WC, Greis KD, Andreassen PR, Barski A, Namekawa SH, SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination. Dev Cell. 2015 Mar 9;32(5):574-88
3	J:292609 Kim JM, Yang YS, Park KH, Ge X, Xu R, Li N, Song M, Chun H, Bok S, Charles JF, Filhol-Cochet O, Boldyreff B, Dinter T, Yu PB, Kon N, Gu W, Takarada T, Greenblatt MB, Shim JH, A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nat Commun. 2020 May 8;11(1):2289
7*	J:168184 Kon N, Kobayashi Y, Li M, Brooks CL, Ludwig T, Gu W, Inactivation of HAUSP in vivo modulates p53 function. Oncogene. 2010 Mar 4;29(9):1270-9
5	J:203102 Kon N, Zhong J, Kobayashi Y, Li M, Szabolcs M, Ludwig T, Canoll PD, Gu W, Roles of HAUSP-mediated p53 regulation in central nervous system development. Cell Death Differ. 2011 Aug;18(8):1366-75
1*	J:335625 Liu C, Sun L, Tan Y, Wang Q, Luo T, Li C, Yao N, Xie Y, Yi X, Zhu Y, Guo T, Ji J, USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Sci Adv. 2023 May 19;9(20):eade3888
1	J:222892 Luo M, Zhou J, Leu NA, Abreu CM, Wang J, Anguera MC, de Rooij DG, Jasin M, Wang PJ, Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis. PLoS Genet. 2015 Jan;11(1):e1004954
1	J:335488 Manea T, Nelson JK, Garrone CM, Hansson K, Evans I, Behrens A, Sancho R, USP7 controls NGN3 stability and pancreatic endocrine lineage development. Nat Commun. 2023 Apr 28;14(1):2457
2	J:326536 Qiao H, Tian Y, Huo Y, Man HY, Role of the DUB enzyme USP7 in dendritic arborization, neuronal migration, and autistic-like behaviors in mice. iScience. 2022 Jul 15;25(7):104595
3	J:240517 Tavana O, Li D, Dai C, Lopez G, Banerjee D, Kon N, Chen C, Califano A, Yamashiro DJ, Sun H, Gu W, HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma. Nat Med. 2016 Oct;22(10):1180-1186
1	J:195854 Zhu Y, Pires KM, Whitehead KJ, Olsen CD, Wayment B, Zhang YC, Bugger H, Ilkun O, Litwin SE, Thomas G, Kozma SC, Abel ED, Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth. PLoS One. 2013;8(1):e54221