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Gene Expression Literature Summary
Symbol
Name
ID
Vangl1
VANGL planar cell polarity 1
MGI:2159344

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7.5 E8 E8.5 E9.5 E10.5 E11.5 E12.5 E13.5 E14.5 E15.5 E17.5 E18.5 E19.5 E P
Immunohistochemistry (section) 2 4 2 1 2 1 4 1
In situ RNA (section) 1 1 2 2 1 1 1 1
Immunohistochemistry (whole mount) 1
In situ RNA (whole mount) 1 1 1 1 1
In situ reporter (knock in) 1 1 2 3 1 1 1 2
Western blot 1 1 1
RT-PCR 1 1 1 1 2 1 1 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Vangl1  VANGL planar cell polarity 1   (Synonyms: KITENIN, Lpp2, mStbm, stbm)
Results  Reference
2J:220460 Andre P, Song H, Kim W, Kispert A, Yang Y, Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation. Development. 2015 Apr 15;142(8):1516-27
6J:157938 Antic D, Stubbs JL, Suyama K, Kintner C, Scott MP, Axelrod JD, Planar cell polarity enables posterior localization of nodal cilia and left-right axis determination during mouse and Xenopus embryogenesis. PLoS One. 2010;5(2):e8999
1J:168261 Babayeva S, Zilber Y, Torban E, Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes. Am J Physiol Renal Physiol. 2011 Feb;300(2):F549-60
1J:218613 Chen J, Laclef C, Moncayo A, Snedecor ER, Yang N, Li L, Takemaru K, Paus R, Schneider-Maunoury S, Clark RA, The ciliopathy gene rpgrip1l is essential for hair follicle development. J Invest Dermatol. 2015 Mar;135(3):701-9
1J:201321 Copley CO, Duncan JS, Liu C, Cheng H, Deans MR, Postnatal refinement of auditory hair cell planar polarity deficits occurs in the absence of Vangl2. J Neurosci. 2013 Aug 28;33(35):14001-16
1J:205269 Cui C, Chatterjee B, Lozito TP, Zhang Z, Francis RJ, Yagi H, Swanhart LM, Sanker S, Francis D, Yu Q, San Agustin JT, Puligilla C, Chatterjee T, Tansey T, Liu X, Kelley MW, Spiliotis ET, Kwiatkowski AV, Tuan R, Pazour GJ, Hukriede NA, Lo CW, Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol. 2013 Nov;11(11):e1001720
1J:205544 Dai D, Li L, Huebner A, Zeng H, Guevara E, Claypool DJ, Liu A, Chen J, Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia. Cell Death Differ. 2013 Jan;20(1):130-8
1J:173143 Dai D, Zhu H, Wlodarczyk B, Zhang L, Li L, Li AG, Finnell RH, Roop DR, Chen J, Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. J Invest Dermatol. 2011 Feb;131(2):302-10
1J:206576 Fukuda T, Kominami K, Wang S, Togashi H, Hirata K, Mizoguchi A, Rikitake Y, Takai Y, Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities. Development. 2014 Jan;141(2):399-409
1J:139139 Garcia-Garcia MJ, Shibata M, Anderson KV, Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo. Development. 2008 Sep;135(18):3053-62
1J:215971 Gegg M, Bottcher A, Burtscher I, Hasenoeder S, Van Campenhout C, Aichler M, Walch A, Grant SG, Lickert H, Flattop regulates basal body docking and positioning in mono- and multiciliated cells. Elife. 2014;3
9J:148751 Liu J, Qi J, Zhu J, Zhang L, Liang Y, Ning Q, Luo X, Effects of Retinoic Acid on the Expressions of Vangl1 and Vangl2 in Mouse Fetuses. J Neurogenet. 2008 Nov 15;22(3):167-179
1J:240026 Minegishi K, Hashimoto M, Ajima R, Takaoka K, Shinohara K, Ikawa Y, Nishimura H, McMahon AP, Willert K, Okada Y, Sasaki H, Shi D, Fujimori T, Ohtsuka T, Igarashi Y, Yamaguchi TP, Shimono A, Shiratori H, Hamada H, A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking. Dev Cell. 2017 Mar 13;40(5):439-452.e4
4J:213956 Pryor SE, Massa V, Savery D, Andre P, Yang Y, Greene ND, Copp AJ, Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals. Development. 2014 Aug;141(16):3153-8
1J:169765 Shafer B, Onishi K, Lo C, Colakoglu G, Zou Y, Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance. Dev Cell. 2011 Feb 15;20(2):177-91
10J:162640 Song H, Hu J, Chen W, Elliott G, Andre P, Gao B, Yang Y, Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning. Nature. 2010 Jul 15;466(7304):378-82
1J:119655 Song MR, Shirasaki R, Cai CL, Ruiz EC, Evans SM, Lee SK, Pfaff SL, T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration. Development. 2006 Dec;133(24):4945-55
5*J:106092 Tissir F, Goffinet AM, Expression of planar cell polarity genes during development of the mouse CNS. Eur J Neurosci. 2006 Feb;23(3):597-607
10*J:132697 Torban E, Patenaude AM, Leclerc S, Rakowiecki S, Gauthier S, Andelfinger G, Epstein DJ, Gros P, Genetic interaction between members of the Vangl family causes neural tube defects in mice. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3449-54
2J:185311 Yin H, Copley CO, Goodrich LV, Deans MR, Comparison of phenotypes between different vangl2 mutants demonstrates dominant effects of the Looptail mutation during hair cell development. PLoS One. 2012;7(2):e31988

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last database update
12/13/2017
MGI 6.11
The Jackson Laboratory