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Gene Expression Literature Summary
Symbol
Name
ID
Sun1
Sad1 and UNC84 domain containing 1
MGI:1924303

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E12.5 E13.5 E14.5 E15.5 E16.5 E18.5 P
Immunohistochemistry (section) 1 1 2 1 3 4
Immunohistochemistry (whole mount) 2
Western blot 1 1 1 1 1 3
RT-PCR 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Sun1  Sad1 and UNC84 domain containing 1   (Synonyms: 4632417G13Rik, 5730434D03Rik, mKIAA0810, Unc84a)
Results  Reference
1*J:304350 Carley E, Stewart RM, Zieman A, Jalilian I, King DE, Zubek A, Lin S, Horsley V, King MC, The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation. Elife. 2021 Mar;:e58541
1J:242462 Daniel K, Trankner D, Wojtasz L, Shibuya H, Watanabe Y, Alsheimer M, Toth A, Mouse CCDC79 (TERB1) is a meiosis-specific telomere associated protein. BMC Cell Biol. 2014 May 22;15:17
6J:263180 Dominguez Gonzalez B, Billion K, Rous S, Pavie B, Lange C, Goodchild R, Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease. Hum Mol Genet. 2018 Jun 15;27(12):2154-2170
2*J:150047 Lei K, Zhang X, Ding X, Guo X, Chen M, Zhu B, Xu T, Zhuang Y, Xu R, Han M, SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10207-12
1J:224364 Marjanovic M, Sanchez-Huertas C, Terre B, Gomez R, Scheel JF, Pacheco S, Knobel PA, Martinez-Marchal A, Aivio S, Palenzuela L, Wolfrum U, McKinnon PJ, Suja JA, Roig I, Costanzo V, Luders J, Stracker TH, CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination. Nat Commun. 2015;6:7676
1J:190404 Morimoto A, Shibuya H, Zhu X, Kim J, Ishiguro K, Han M, Watanabe Y, A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis. J Cell Biol. 2012 Jul 23;198(2):165-72
2J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167
3J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088
3J:246890 Stroud MJ, Feng W, Zhang J, Veevers J, Fang X, Gerace L, Chen J, Nesprin 1alpha2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle. J Cell Biol. 2017 Jul 03;216(7):1915-1924
1J:168852 Yu J, Lei K, Zhou M, Craft CM, Xu G, Xu T, Zhuang Y, Xu R, Han M, KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. Hum Mol Genet. 2011 Mar 15;20(6):1061-73
1J:346053 Zhang J, Ruiz M, Bergh PO, Henricsson M, Stojanovic N, Devkota R, Henn M, Bohlooly-Y M, Hernandez-Hernandez A, Alsheimer M, Boren J, Pilon M, Shibuya H, Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2. Nat Commun. 2024 Mar 14;15(1):2315
2J:155113 Zhang X, Lei K, Yuan X, Wu X, Zhuang Y, Xu T, Xu R, Han M, SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron. 2009 Oct 29;64(2):173-87

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory