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Symbol Name ID |
Rptor
regulatory associated protein of MTOR, complex 1 MGI:1921620 |
| Age | E0.5 | E9.5 | E10.5 | E11.5 | E15.5 | E | A |
| In situ RNA (section) | 1 | 1 | 1 | ||||
| In situ protein (whole mount) | 1 | ||||||
| Western blot | 1 | 1 | 1 | 2 |
| Rptor regulatory associated protein of MTOR, complex 1 (Synonyms: 4932417H02Rik, mKIAA1303, Rap, raptor) | |
| Results | Reference |
| 1 | J:137592 Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM, Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. Dev Cell. 2006 Dec;11(6):859-71 |
| 1* | J:154667 Hasumi Y, Baba M, Ajima R, Hasumi H, Valera VA, Klein ME, Haines DC, Merino MJ, Hong SB, Yamaguchi TP, Schmidt LS, Linehan WM, Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18722-7 |
| 1 | J:137601 Ikenoue T, Inoki K, Yang Q, Zhou X, Guan KL, Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling. EMBO J. 2008 Jul 23;27(14):1919-31 |
| 3* | J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86 |
| 1 | J:177840 Magri L, Cambiaghi M, Cominelli M, Alfaro-Cervello C, Cursi M, Pala M, Bulfone A, Garcia-Verdugo JM, Leocani L, Minicucci F, Poliani PL, Galli R, Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions. Cell Stem Cell. 2011 Nov 4;9(5):447-62 |
| 1 | J:153804 Vijayaraj P, Kroger C, Reuter U, Windoffer R, Leube RE, Magin TM, Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor. J Cell Biol. 2009 Oct 19;187(2):175-84 |
| 1* | J:154371 Xu XY, Zhang Z, Su WH, Zhang Y, Yu YQ, Li YX, Zong ZH, Yu BZ, Characterization of p70 S6 kinase 1 in early development of mouse embryos. Dev Dyn. 2009 Oct 29;238(12):3025-3034 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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