Gene Expression Literature Summary

• Symbol: Dnm1l
• Name: dynamin 1-like
• ID: MGI:1921256

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E4.5	E5.5	E9.5	E10.5	E13.5	E14.5	E16.5	E18	E	P
Immunohistochemistry (section)	1	1	1	1						2
In situ RNA (section)						1				1
Immunohistochemistry (whole mount)										1
Western blot					1		1		1	10
RT-PCR						1	1	1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dnm1l  dynamin 1-like   (Synonyms: 6330417M19Rik, Dnmlp1, Drp1, python)
Results	Reference
3	J:326254 Adhikari D, Lee IW, Al-Zubaidi U, Liu J, Zhang QH, Yuen WS, He L, Winstanley Y, Sesaki H, Mann JR, Robker RL, Carroll J, Depletion of oocyte dynamin-related protein 1 shows maternal-effect abnormalities in embryonic development. Sci Adv. 2022 Jun 17;8(24):eabl8070
2	J:100324 Bulfone A, Carotenuto P, Faedo A, Aglio V, Garzia L, Bello AM, Basile A, Andre A, Cocchia M, Guardiola O, Ballabio A, Rubenstein JL, Zollo M, Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. J Neurosci. 2005 Aug 17;25(33):7586-600
1	J:343469 Ding Y, He Z, Sha Y, Kee K, Li L, Eif4enif1 haploinsufficiency disrupts oocyte mitochondrial dynamics and leads to subfertility. Development. 2023 Dec 1;150(23):dev202151
1*	J:228859 Fu J, Yu HM, Chiu SY, Mirando AJ, Maruyama EO, Cheng JG, Hsu W, Disruption of SUMO-specific protease 2 induces mitochondria mediated neurodegeneration. PLoS Genet. 2014 Oct;10(10):e1004579
1	J:330579 Gambarotto L, Metti S, Chrisam M, Cerqua C, Sabatelli P, Armani A, Zanon C, Spizzotin M, Castagnaro S, Strappazzon F, Grumati P, Cescon M, Braghetta P, Trevisson E, Cecconi F, Bonaldo P, Ambra1 deficiency impairs mitophagy in skeletal muscle. J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2211-2224
1	J:158142 Ishihara N, Nomura M, Jofuku A, Kato H, Suzuki SO, Masuda K, Otera H, Nakanishi Y, Nonaka I, Goto Y, Taguchi N, Morinaga H, Maeda M, Takayanagi R, Yokota S, Mihara K, Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat Cell Biol. 2009 Aug;11(8):958-66
2	J:224310 Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N, Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. Mol Cell Biol. 2015 Jan;35(1):211-23
1	J:341543 Meng TG, Guo JN, Zhu L, Yin Y, Wang F, Han ZM, Lei L, Ma XS, Xue Y, Yue W, Nie XQ, Zhao ZH, Zhang HY, Sun SM, Ouyang YC, Hou Y, Schatten H, Ju Z, Ou XH, Wang ZB, Wong CCL, Li Z, Sun QY, NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition. Adv Sci (Weinh). 2023 Sep;10(27):e2301940
1	J:307395 Mirra S, Garcia-Arroyo R, B Domenech E, Gavalda-Navarro A, Herrera-Ubeda C, Oliva C, Garcia-Fernandez J, Artuch R, Villarroya F, Marfany G, CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina. Neurobiol Dis. 2021 Aug;156:105405
1*	J:226977 Moriya M, Inoue S, Miyagawa-Tomita S, Nakashima Y, Oba D, Niihori T, Hashi M, Ohnishi H, Kure S, Matsubara Y, Aoki Y, Adult mice expressing a Braf Q241R mutation on an ICR/CD-1 background exhibit a cardio-facio-cutaneous syndrome phenotype. Hum Mol Genet. 2015 Dec 20;24(25):7349-60
2	J:325556 Pernaute B, Perez-Montero S, Sanchez Nieto JM, Di Gregorio A, Lima A, Lawlor K, Bowling S, Liccardi G, Tomas A, Meier P, Sesaki H, Rutter GA, Barbaric I, Rodriguez TA, DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism. Dev Cell. 2022 Jun 6;57(11):1316-1330.e7
1	J:304183 Ponce JM, Coen G, Spitler KM, Dragisic N, Martins I, Hinton A Jr, Mungai M, Tadinada SM, Zhang H, Oudit GY, Song LS, Li N, Sicinski P, Strack S, Abel ED, Mitchell C, Hall DD, Grueter CE, Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics. J Am Heart Assoc. 2020 Apr 7;9(7):e014366
1	J:331835 Salazar-Petres E, Pereira-Carvalho D, Lopez-Tello J, Sferruzzi-Perri AN, Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice. Biol Reprod. 2022 Jun 13;106(6):1292-1311
3	J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7
3	J:153835 Wakabayashi J, Zhang Z, Wakabayashi N, Tamura Y, Fukaya M, Kensler TW, Iijima M, Sesaki H, The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice. J Cell Biol. 2009 Sep 21;186(6):805-16
2*	J:324720 Zhao Q, Yan S, Lu J, Parker DJ, Wu H, Sun Q, Crossman DK, Liu S, Wang Q, Sesaki H, Mitra K, Liu K, Jiao K, Drp1 regulates transcription of ribosomal protein genes in embryonic hearts. J Cell Sci. 2022 Feb 15;135(4):jcs258956