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Gene Expression Literature Summary
Symbol
Name
ID
Cul4b
cullin 4B
MGI:1919834

6 matching records from 6 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2 E3 E3.5 E4 E4.5 E5 E7.5 E9.5 E10.5 A
In situ protein (section) 1 3 2
In situ protein (whole mount) 1 1 1 1 1
Western blot 3
RT-PCR 1 1 1 1 1 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
Cul4b  cullin 4B   (Synonyms: 2700050M05Rik)
Results  Reference
1J:204566 Gendrel AV, Tang YA, Suzuki M, Godwin J, Nesterova TB, Greally JM, Heard E, Brockdorff N, Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
4J:199139 Jiang B, Zhao W, Yuan J, Qian Y, Sun W, Zou Y, Guo C, Chen B, Shao C, Gong Y, Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development. PLoS One. 2012;7(5):e37070
6J:199210 Liu L, Yin Y, Li Y, Prevedel L, Lacy EH, Ma L, Zhou P, Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis. Cell Res. 2012 Aug;22(8):1258-69
1J:116773 Oda M, Yamagiwa A, Yamamoto S, Nakayama T, Tsumura A, Sasaki H, Nakao K, Li E, Okano M, DNA methylation regulates long-range gene silencing of an X-linked homeobox gene cluster in a lineage-specific manner. Genes Dev. 2006 Dec 15;20(24):3382-94
9J:205485 Yu C, Zhang YL, Pan WW, Li XM, Wang ZW, Ge ZJ, Zhou JJ, Cang Y, Tong C, Sun QY, Fan HY, CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science. 2013 Dec 20;342(6165):1518-21
2J:196602 Zou Y, Mi J, Wang W, Lu J, Zhao W, Liu Z, Hu H, Yang Y, Gao X, Jiang B, Shao C, Gong Y, CUL4B promotes replication licensing by up-regulating the CDK2-CDC6 cascade. J Cell Biol. 2013 Mar 18;200(6):743-56

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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory