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Gene Expression Literature Summary
Symbol
Name
ID
Insc
INSC spindle orientation adaptor protein
MGI:1917942

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E8 E9.5 E10.5 E11.5 E12.5 E13.5 E14 E14.5 E15.5 E16.5 E17.5 E P
Immunohistochemistry (section) 1 1 1 1
In situ RNA (section) 1 1 2 1
Immunohistochemistry (whole mount) 1 1
In situ RNA (whole mount) 1 1 1
In situ reporter (knock in) 1 1 1 1
Western blot 1 1 1 1
RT-PCR 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Insc  INSC spindle orientation adaptor protein   (Synonyms: 3830422K02Rik, Inscuteable)
Results  Reference
2J:112701 Bailey PJ, Klos JM, Andersson E, Karlen M, Kallstrom M, Ponjavic J, Muhr J, Lenhard B, Sandelin A, Ericson J, A global genomic transcriptional code associated with CNS-expressed genes. Exp Cell Res. 2006 Oct 1;312(16):3108-19
2*J:167828 El-Hashash AH, Warburton D, Cell polarity and spindle orientation in the distal epithelium of embryonic lung. Dev Dyn. 2011 Feb;240(2):441-5
2J:237485 Harris L, Zalucki O, Gobius I, McDonald H, Osinki J, Harvey TJ, Essebier A, Vidovic D, Gladwyn-Ng I, Burne TH, Heng JI, Richards LJ, Gronostajski RM, Piper M, Transcriptional regulation of intermediate progenitor cell generation during hippocampal development. Development. 2016 Dec 15;143(24):4620-4630
1J:308321 Lau EO, Damiani D, Chehade G, Ruiz-Reig N, Saade R, Jossin Y, Aittaleb M, Schakman O, Tajeddine N, Gailly P, Tissir F, DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction. Elife. 2021 Apr 26;10:e61974
2J:178712 Postiglione MP, Juschke C, Xie Y, Haas GA, Charalambous C, Knoblich JA, Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron. 2011 Oct 20;72(2):269-84
7J:214064 Tarchini B, Jolicoeur C, Cayouette M, A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells. Dev Cell. 2013 Oct 14;27(1):88-102
1J:222450 Uribe V, Badia-Careaga C, Casanova JC, Dominguez JN, de la Pompa JL, Sanz-Ezquerro JJ, Arid3b is essential for second heart field cell deployment and heart patterning. Development. 2014 Nov;141(21):4168-81
1*J:281175 Yorgan TA, Peters S, Amling M, Schinke T, Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling. Bone. 2019 Oct;127:155-163
7*J:107579 Zigman M, Cayouette M, Charalambous C, Schleiffer A, Hoeller O, Dunican D, McCudden CR, Firnberg N, Barres BA, Siderovski DP, Knoblich JA, Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina. Neuron. 2005 Nov 23;48(4):539-45

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory