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Symbol Name ID |
Wwtr1
WW domain containing transcription regulator 1 MGI:1917649 |
| Age | E0.5 | E1 | E2.5 | E3 | E3.5 | E4 | E8.5 | E9 | E9.5 | E10.5 | E11.5 | E12.5 | E13.5 | E14.5 | E15.5 | E16.5 | E17.5 | E18 | E18.5 | E | A |
| In situ protein (section) | 1 | 1 | 1 | 1 | 1 | 1 | 3 | ||||||||||||||
| In situ RNA (section) | 2 | 2 | 1 | 3 | 1 | 1 | 1 | 1 | |||||||||||||
| In situ protein (whole mount) | 1 | 1 | |||||||||||||||||||
| In situ RNA (whole mount) | 1 | 1 | 2 | 2 | 2 | 1 | 1 | 1 | |||||||||||||
| In situ reporter (knock in) | 1 | 1 | 1 | 1 | |||||||||||||||||
| Western blot | 1 | 1 | 1 | 1 | |||||||||||||||||
| RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | |||||||||
| cDNA clones | 1 |
| Wwtr1 WW domain containing transcription regulator 1 (Synonyms: 2310058J06Rik, 2610021I22Rik, TAZ, transcriptional coactivator with PDZ binding motif) | |
| Results | Reference |
| 13 | J:144755 Di Palma T, D'Andrea B, Liguori GL, Liguoro A, de Cristofaro T, Del Prete D, Pappalardo A, Mascia A, Zannini M, TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation. Exp Cell Res. 2009 Jan 15;315(2):162-75 |
| 1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
| 2 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
| 1* | J:171409 GUDMAP: the GenitoUrinary Development Molecular Anatomy Project, http://www.gudmap.org. 2004; |
| 5 | J:119488 Hossain Z, Ali SM, Ko HL, Xu J, Ng CP, Guo K, Qi Z, Ponniah S, Hong W, Hunziker W, Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1631-6 |
| 7 | J:132020 Makita R, Uchijima Y, Nishiyama K, Amano T, Chen Q, Takeuchi T, Mitani A, Nagase T, Yatomi Y, Aburatani H, Nakagawa O, Small EV, Cobo-Stark P, Igarashi P, Murakami M, Tominaga J, Sato T, Asano T, Kurihara Y, Kurihara H, Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ. Am J Physiol Renal Physiol. 2008 Mar;294(3):F542-53 |
| 3* | J:103937 Murakami M, Tominaga J, Makita R, Uchijima Y, Kurihara Y, Nakagawa O, Asano T, Kurihara H, Transcriptional activity of Pax3 is co-activated by TAZ. Biochem Biophys Res Commun. 2006 Jan 13;339(2):533-9 |
| 7 | J:147050 Nishioka N, Inoue K, Adachi K, Kiyonari H, Ota M, Ralston A, Yabuta N, Hirahara S, Stephenson RO, Ogonuki N, Makita R, Kurihara H, Morin-Kensicki EM, Nojima H, Rossant J, Nakao K, Niwa H, Sasaki H, The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell. 2009 Mar;16(3):398-410 |
| 12 | J:89484 Park KS, Whitsett JA, Di Palma T, Hong JH, Yaffe MB, Zannini M, TAZ interacts with TTF-1 and regulates expression of surfactant protein-C. J Biol Chem. 2004 Apr 23;279(17):17384-90 |
| 2 | J:160312 Varelas X, Miller BW, Sopko R, Song S, Gregorieff A, Fellouse FA, Sakuma R, Pawson T, Hunziker W, McNeill H, Wrana JL, Attisano L, The Hippo pathway regulates Wnt/beta-catenin signaling. Dev Cell. 2010 Apr 20;18(4):579-91 |
| 3* | J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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